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Martin Kortuem, MD
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Journal Articles

Real-World Experience with Minimal Residual Disease Testing with Next Generation Flow Cytometry and Functional Imaging in Multiple Myeloma

David Böckle, MD, Paula Tabares Gaviria, Xiang Zhou, MD, Janin Messerschmidt, MD, Lukas Scheller, Maximilian Johannes Steinhardt, MD, Elena Seebacher, Maria Ulbrich, Anke Heidemeier, MD, Andreas Buck, MD, Hermann Einsele, MD, Andreas Beilhack, MD, Martin Kortuem, MD, Leo Rasche, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-140772
Published: 2020
Journal Articles

Mimicking the Myeloma Niche: A 3D Bone-Derived Co-Culture System to Selectively Assess Bystander BMSCs and to Perform High-Throughput Drug Screening in Multiple Myeloma

Johannes M. Waldschmidt, MD, Dagmar Wider, Andreas R. Thomsen, MD, Claudius Klein, Christine Aldrian, Martin Kortuem, MD, Marie Follo, PhD, Julia Schüler, DVM, PhD, Justus Duyster, MD PhD, Monika Engelhardt, MD PhD, Ralph Wäsch, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1822.
https://doi.org/10.1182/blood.V126.23.1822.1822
Published: 2015
Journal Articles

Targeted Sequencing of Relapsed/Refractory Myeloma Patients Identifies an Enrichment of Mutations in Cereblon and MAPK Pathways

Elias Karl Mai, MD, K. Martin Kortuem, MD, Nur Hanafiah, Santiago Barrio, Laura Ann Bruins, Maximilian Merz, MD, Jing Xu, Koenuel Pashayeva, MD, Yuan-Xiao Zhu, Chang-Xin Shi, PhD, R. Alexander Stewart, Patrick Jedlowski, Mindaugas Andrulis, MD, Anna Jauch, Prof., Jens Hillengass, MD, Hartmut Goldschmidt, MD, P. Leif Bergsagel, MD PhD, Esteban Braggio, PhD, A. Keith Stewart, MD, Marc Steffen Raab, MD PhD
Journal: Blood
Blood (2015) 126 (23): 723.
https://doi.org/10.1182/blood.V126.23.723.723
Published: 2015
Journal Articles

Ikaros Degradation Efficiency Correlates with Response of Multiple Myeloma (MM) Cells to IMiD Therapy and Is Blocked By Proteasome Inhibitors

Chang-Xin Shi, PhD, Yuan Xiao Zhu, PhD, Patrick Jedlowski, Laura Bruins, Martin Kortuem, MD, A. Keith Stewart, MD
Journal: Blood
Blood (2014) 124 (21): 2247.
https://doi.org/10.1182/blood.V124.21.2247.2247
Published: 2014
Journal Articles

Development and Results of a Multiple Myeloma Specific Custom 77-Gene Mutation Panel for Clinical Targeted Sequencing

K. Martin Kortuem, MD, A. Keith Stewart, MD, Laura Ann Bruins, Gregory Ahmann, BS, George Vasmatzis, PhD, S. Vincent Rajkumar, MD, Shaji Kumar, MD, Angela Dispenzieri, MD, Martha Q Lacy, MD, Morie A Gertz, MD, Rafael Fonseca, MD, Mia Champion, PhD, P. Leif Bergsagel, MD, Esteban Braggio, PhD
Journal: Blood
Blood (2014) 124 (21): 169.
https://doi.org/10.1182/blood.V124.21.169.169
Published: 2014
Journal Articles

Development Of a 47 Gene Sequencing Panel For Common Mutations Present In Multiple Myeloma : Preliminary Results In 77 p53 Deleted Patients

K. Martin Kortuem, MD, Christian Langer, MD, Esteban Braggio, Ph.D., Scott Van Wier, Jan Egan, PhD, Laura Bruins, Jessica Schmidt, Lars Bullinger, MD, PhD, Miriam Kull, MD, Stefan Knop, MD, Hermann Einsele, MD, A. Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2013) 122 (21): 4449.
https://doi.org/10.1182/blood.V122.21.4449.4449
Published: 2013
Journal Articles

Cereblon Expression Predicts Response, Progression Free and Overall Survival After Pomalidomide and Dexamethasone Therapy in Multiple Myeloma

Steven R. Schuster, MD, Klaus Martin Kortuem, MD, Yuan Xiao Zhu, PhD, Esteban Braggio, Ph.D., Chang-Xin Shi, PhD, Laura Bruins, Jessica Schmidt, Gregory Ahmann, BS, Shaji K. Kumar, MD, S. Vincent Rajkumar, Joseph R. Mikhael, MD, Vivek Roy, M.D., Betsy R. LaPlant, Kristina Laumann, Bart Barlogie, MD, John D Shaughnessy, Jr., PhD, Rafael Fonseca, MD, Leif Bergsagel, MD, Martha Q Lacy, MD, Keith Stewart, MD
Journal: Blood
Blood (2012) 120 (21): 194.
https://doi.org/10.1182/blood.V120.21.194.194
Published: 2012
Journal Articles

The Myeloma Genome in Drug Refractory Extra-Medullary Disease Identifies Mutations in Proteasome, Cereblon and Glucocorticoid Pathways

Jan Egan, PhD, Klaus Martin Kortuem, MD, Chang-Xin Shi, PhD, Jessica Schmidt, David Craig, PhD, John Carpten, PhD, Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 3968.
https://doi.org/10.1182/blood.V120.21.3968.3968
Published: 2012
Journal Articles

Activity of Single Agent Drugs in Phase I and II Trials Best Predicts Future Clinical Utility in Multiple Myeloma

Klaus Martin Kortuem, MD, Steven R Schuster, MD, Meaghan L. Khan, MD, Kaitlyn E. Zidich, Victor H Jimenez-Zepeda, MD, Rafael Fonseca, MD, Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 4034.
https://doi.org/10.1182/blood.V120.21.4034.4034
Published: 2012
Journal Articles

Cereblon Binding IMiD Small Molecules Mediate Myeloma Cell Death Via IRF4

Yuan Xiao Zhu, Ph.D., Chang-Xin Shi, Ph.D., Laura Bruins, Klaus Martin Kortuem, MD, Jessica Schmidt, Xiu-Bao Chang, Ph.D., Esteban Braggio, Ph.D., Leif Bergsagel, M.D., Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 1807.
https://doi.org/10.1182/blood.V120.21.1807.1807
Published: 2012