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Journal Articles

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-142314

Published: 2020

Journal Articles

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Laura Hinze, Sabine Schreek, Andre Zeug, PhD, Evgeni Ponimaskin, PhD, Roxane Labrosse, MD FRCPC, James Degar, Gabriela Chiosis, PhD, Sung-Yun Pai, MD, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Martin Stanulla, MD, Alejandro Gutierrez, MD

Blood (2019) 134 (Supplement_1): 169.

https://doi.org/10.1182/blood-2019-126633

Published: 2019

Journal Articles

Longitudinal Multilevel Omic Analysis of Pediatric T-ALL Reveals Distinct Mechanisms for Disease Progression in Type 1 and in Type 2 Relapses

Blood (2018) 132 (Supplement 1): 2826.

https://doi.org/10.1182/blood-2018-99-117978

Published: 2018

Journal Articles

Methotrexate-Associated Toxicity in Children with Down Syndrome and Acute Lymphoblastic Leukemia during Consolidation Therapy with High Dose Methotrexate According to ALL-BFM Treatment Regimen

Mirko Kroll, Kirsten Bleckmann, MD, Anja Möricke, MD, Denis Martin Schewe, MD, Martin Stanulla, MD PhD, Martin Zimmermann, PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD

Blood (2018) 132 (Supplement 1): 1378.

https://doi.org/10.1182/blood-2018-99-112114

Published: 2018

Journal Articles

Pediatric T-ALLs Developing into a Type 2 Relapse Originate from Cells That Carry the Potential of Variable Maturation into Subclones with Distinct Chromatin Landscapes

Blood (2018) 132 (Supplement 1): 1545.

https://doi.org/10.1182/blood-2018-99-118255

Published: 2018

Journal Articles

TCF3-Hlf Hijacks ERG to Activate Leukemia-Critical Super-Enhancers in t(17;19) Leukemia

Yun Huang, PhD, Brice Mouttet, Hans-Jörg Warnatz, PhD, Maria Pamela Dobay, PhD, Blerim Marovca, Silvia Jenni, PhD, Martin Schrappe, MD PhD, Martin Stanulla, MD PhD, Marie-Laure Yaspo, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD

Blood (2017) 130 (Supplement 1): 561.

https://doi.org/10.1182/blood.V130.Suppl_1.561.561

Published: 2017

Journal Articles

The Impact of Sex on Clinical Outcome and Toxicity in Children and Adolescents with Acute Lymphoblastic Leukemia. a Report from the BFM Study Group

Alexander Claviez, MD, Nina Brinkmeier, Martin Stanulla, MD PhD, Martin Zimmermann, PhD, Martin Schrappe, MD PhD, Anja Moericke, MD

Blood (2017) 130 (Supplement 1): 2555.

https://doi.org/10.1182/blood.V130.Suppl_1.2555.2555

Published: 2017

Journal Articles

Genome-Wide Association Study (GWAS) of High-Risk Minimal Residual Disease and Relapse in B-Cell Acute Lymphoblastic Leukemia on Trial AIEOP-BFM ALL 2000

Laura Hinze, Stefanie V. Junk, PhD, Norman Klein, Anja Moricke, MD, Gunnar Cario, MD, Christian P. Kratz, MD, Richard S Houlston, MD PhD, Claus R Bartam, MD, Rolf Koehler, PhD, Martin Zimmermann, PhD, Martin Schrappe, MD PhD, Martin Stanulla, MD PhD

Blood (2017) 130 (Supplement 1): 3981.

https://doi.org/10.1182/blood.V130.Suppl_1.3981.3981

Published: 2017

Journal Articles

PDX Models Recapitulate Genetics and Epigenetics of Pediatric T-Cell Leukemia

Blood (2017) 130 (Supplement 1): 2723.

https://doi.org/10.1182/blood.V130.Suppl_1.2723.2723

Published: 2017

Journal Articles

Relapsing Pediatric T-Cell Acute Lymphoblastic Leukemia Downregulates T-Cell Properties and Upregulates Cell Adhesion

Blood (2017) 130 (Supplement 1): 2726.

https://doi.org/10.1182/blood.V130.Suppl_1.2726.2726

Published: 2017

Journal Articles

MAP3K7 Is Recurrently Deleted in Pediatric T-Lymphoblastic Leukemia and Affects Cell Proliferation Independently of NF-κB

David M. Cordas dos Santos, Juliane Eilers, Alfonso Vizcaino, Elena Orlova, Martin Zimmermann, PhD, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Kathleen Börner, PhD, Dirk Grimm, PhD, Martina Muckenthaler, Andreas E. Kulozik, MD PhD, Joachim B. Kunz, MD

Blood (2017) 130 (Supplement 1): 1447.

https://doi.org/10.1182/blood.V130.Suppl_1.1447.1447

Published: 2017

Journal Articles

TP53 , ETV6 and RUNX1 Germline Variants in Patients Developing Secondary Neoplasms after Treatment for Childhood Acute Lymphoblastic Leukemia

Stefanie V. Junk, PhD, Norman Klein, Sabine Schreek, Martin Zimmermann, PhD, Anja Möricke, MD, Kirsten Bleckmann, Gunnar Cario, MD, Martin Schrappe, MD PhD, Christian P. Kratz, MD, Martin Stanulla, MD PhD

Blood (2017) 130 (Supplement 1): 884.

https://doi.org/10.1182/blood.V130.Suppl_1.884.884

Published: 2017

Journal Articles

Common Genetic Variants in Trypsin Regulating Genes Are Associated with AsparAginase-Associated Pancreatitis in Children with Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Study

Benjamin Ole Wolthers, MD, Thomas Leth Frandsen, MD PhD, Andishe Attarbaschi, MD, Shlomit Barzilai, MD, Antonella Colombini, Gabriele Escherich, MD, Marie Grosjean, Ramneek Gupta, PhD, Der-Cherng Liang, MD, Anja Moricke, MD, Chirag J Patel, PhD, Kirsten K Rasmussen, Sujith Samarasinghe, Inge M. Van Der Sluis, MD PhD, Martin Stanulla, MD PhD, Morten Tulstrup, MD, Ester Zapotocka, MD, Kjeld Schmiegelow, MD DMSc

Blood (2017) 130 (Supplement 1): 885.

https://doi.org/10.1182/blood.V130.Suppl_1.885.885

Published: 2017

Journal Articles

The Combination of MRD and Copy Number Alterations (CNAs) Defines an Ultra-High Risk Group of Children with Primary T-Lymphoblastic Leukemia (T-ALL)

Joachim B. Kunz, MD, Julia Seemann, Martin Zimmermann, PhD, Paulina Richter-Pechanska, Obul Reddy Bandapalli, PhD, Elena Orlova, Gunnar Cario, Martin Stanulla, MD, Martin Schrappe, MD PhD, Marketa Zaliova, Jan Trka, MD PhD, Renate Panzer-Grümayer, MD, Georg Mann, MD, Martina U. Muckenthaler, PhD, Jan O. Korbel, PhD, Andreas E Kulozik, MD PhD

Blood (2016) 128 (22): 2911.

https://doi.org/10.1182/blood.V128.22.2911.2911

Published: 2016

Journal Articles

2% of Healthy Newborns Reveal ETV6-RUNX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Daniel Schaefer, MSc, Marianne Olsen, MD, Ulrik Lausten-Thomsen, MD PhD, Cyrill Schipp, MSc, Martin Stanulla, MD, Robert K. Slany, PhD, Kjeld Schmiegelow, MD DMSc, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2016) 128 (22): 4082.

https://doi.org/10.1182/blood.V128.22.4082.4082

Published: 2016

Journal Articles

Identification of an Ultra High-Risk and Targetable Molecular Signature in Relapsed Pediatric T-ALL

Paulina Richter-Pechanska, PhD, Joachim B. Kunz, MD, Jana Hof, Martin Zimmermann, PhD, Tobias Rausch, PhD, Obul Reddy Bandapalli, PhD, Elena Orlova, Greta Scapinello, Judit Sagi, Martin Stanulla, MD, Martin Schrappe, MD PhD, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Vladimir Benes, PhD, Jan O. Korbel, PhD, Martina U. Muckenthaler, PhD, Andreas E Kulozik, MD PhD

Blood (2016) 128 (22): 1084.

https://doi.org/10.1182/blood.V128.22.1084.1084

Published: 2016

Journal Articles

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia Relapsing after Allogeneic Stem Cell Transplantation

Jessica I Hoell, MD, Sebastian Ginzel, MSc, Cornelia Eckert, PhD, Michael Gombert, PhD, Ute Fischer, PhD, Martin Stanulla, MD, Martin Schrappe, MD PhD, Udo zur Stadt, PhD, Peter Bader, MD, Brigitte Strahm, MD, Julia Alten, Anja Moericke, MD, Gabriele Escherich, MD, Arend Stackelberg, MD, Christina Peters, MD, Arndt Borkhardt, MD, Roland Meisel, MD

Blood (2016) 128 (22): 601.

https://doi.org/10.1182/blood.V128.22.601.601

Published: 2016

Journal Articles

Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Report on Clinical Presentation and Outcome

Blood (2016) 128 (22): 585.

https://doi.org/10.1182/blood.V128.22.585.585

Published: 2016

Journal Articles

Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Blood (2016) 128 (22): LBA-2.

https://doi.org/10.1182/blood.V128.22.LBA-2.LBA-2

Published: 2016

Journal Articles

Drug Response Profiling to Identify Selective Pharmacological Activity in Drug Resistant ALL

Viktoras Frismantas, MSc, Maria Pamela Dobay, PhD, Anna Rinaldi, PhD, Kunz Joachim, MD, Blerim Marovca, Peter Horvath, PhD, Mauro Delorenzi, PhD, Gunnar Cario, MD, Martin Schrappe, MD, Martin Stanulla, MD, Andreas E. Kulozik, MD PhD, Martina U. Muckenthaler, PhD, Arend Stackelberg, MD, Cornelia Eckert, Thomas Radimerski, PhD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD

Blood (2015) 126 (23): 2532.

https://doi.org/10.1182/blood.V126.23.2532.2532

Published: 2015

NARROW

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Longitudinal Multilevel Omic Analysis of Pediatric T-ALL Reveals Distinct Mechanisms for Disease Progression in Type 1 and in Type 2 Relapses

Methotrexate-Associated Toxicity in Children with Down Syndrome and Acute Lymphoblastic Leukemia during Consolidation Therapy with High Dose Methotrexate According to ALL-BFM Treatment Regimen

Pediatric T-ALLs Developing into a Type 2 Relapse Originate from Cells That Carry the Potential of Variable Maturation into Subclones with Distinct Chromatin Landscapes

TCF3-Hlf Hijacks ERG to Activate Leukemia-Critical Super-Enhancers in t(17;19) Leukemia

The Impact of Sex on Clinical Outcome and Toxicity in Children and Adolescents with Acute Lymphoblastic Leukemia. a Report from the BFM Study Group

Genome-Wide Association Study (GWAS) of High-Risk Minimal Residual Disease and Relapse in B-Cell Acute Lymphoblastic Leukemia on Trial AIEOP-BFM ALL 2000

PDX Models Recapitulate Genetics and Epigenetics of Pediatric T-Cell Leukemia

Relapsing Pediatric T-Cell Acute Lymphoblastic Leukemia Downregulates T-Cell Properties and Upregulates Cell Adhesion

MAP3K7 Is Recurrently Deleted in Pediatric T-Lymphoblastic Leukemia and Affects Cell Proliferation Independently of NF-κB

TP53 , ETV6 and RUNX1 Germline Variants in Patients Developing Secondary Neoplasms after Treatment for Childhood Acute Lymphoblastic Leukemia

Common Genetic Variants in Trypsin Regulating Genes Are Associated with AsparAginase-Associated Pancreatitis in Children with Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Study

The Combination of MRD and Copy Number Alterations (CNAs) Defines an Ultra-High Risk Group of Children with Primary T-Lymphoblastic Leukemia (T-ALL)

2% of Healthy Newborns Reveal ETV6-RUNX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Identification of an Ultra High-Risk and Targetable Molecular Signature in Relapsed Pediatric T-ALL

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia Relapsing after Allogeneic Stem Cell Transplantation

Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia: A Ponte Di Legno Toxicity Working Group Report on Clinical Presentation and Outcome

Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Drug Response Profiling to Identify Selective Pharmacological Activity in Drug Resistant ALL

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American Society of Hematology

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American Society of Hematology

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