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Martin Stogniew
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Journal Articles

Dual Targeting of Mitochondrial Unfolded Protein Response and BCL2 in Acute Myeloid Leukemia

Free
Ran Zhao, BS, Sarah Zarabi, MD, Takenobu Nii, PhD, Ondrej Halgas, PhD, Yulia Jitkova, PhD, Vivian Ruvolo, Lauren Heese, Yuki Nishida, MD PhD, Gautam M. Borthakur, MD, Kensuke Kojima, MD PhD, Martin Stogniew, Wolfgang Oster, MD, Emil Pai, PhD, Eric Davis, MD, Hagop M. Kantarjian, MD, Aaron D Schimmer, MD PhD, Michael Andreeff, MD PhD, Jo Ishizawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2562.
https://doi.org/10.1182/blood-2019-127101
Published: 2019
Journal Articles

Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia

Free
Yongwei Su, Xinyu Li, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Katie Hege, Yu Fukuda, John D. Schuetz, PhD, Joshua E. Allen, PhD, Martin Stogniew, Varun Vijay Prabhu, BPharm, MS, PhD, Jeffrey W. Taub, MD, Hai Lin, MD, Yubin Ge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3936.
https://doi.org/10.1182/blood-2018-99-116997
Published: 2018
Journal Articles

ONC213, a Novel Second Generation Analog of ONC201, Shows Promising Anti-Leukemic Activity Against AML Cells In Vitro and In Vivo

Free
Yongwei Su, Xinyu Li, Holly Edwards, Joshua E. Allen, PhD, Martin Stogniew, Varun Vijay Prabhu, BPharm, MS, PhD, Jeffrey W. Taub, MD, Hai Lin, Yubin Ge, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3822.
https://doi.org/10.1182/blood.V130.Suppl_1.3822.3822
Published: 2017
Journal Articles

The Novel Imipridone ONC212 Induces Pronounced Anti-Leukemia Effects in Vitro and In Vivo and Is Highly Synergistic with the BCL-2 Inhibitor ABT-199

Free
Takenobu Nii, PhD, Jo Ishizawa, MD PhD, Varun Vijay Prabhu, BPharm, MS, PhD, Vivian Ruvolo, PhD, Neel Madhukar, Ran Zhao, Hong Mu, MD PhD, Lauren Heese, Kensuke Kojima, MD PhD, Mathew Garnett, Ultan McDermott, Cyril H Benes, Neil Charter, Sean Deacon, Olivier Elemento, PhD, Joshua E. Allen, PhD, Wolfgang Oster, MD, Martin Stogniew, Michael Andreeff, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2616.
https://doi.org/10.1182/blood.V130.Suppl_1.2616.2616
Published: 2017
Journal Articles

Potent Anti-Leukemic Effects of Small Molecule ONC212, a Member of the Imipridone Class of Anti-Cancer Compounds

Free
Varun V Prabhu, PhD, Rohinton S Tarapore, PhD, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jessica M Wagner, Wafik S. El-Deiry, MD PhD, Martin Stogniew, PhD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD
Journal: Blood
Blood (2016) 128 (22): 5133.
https://doi.org/10.1182/blood.V128.22.5133.5133
Published: 2016
Journal Articles

ONC212 Is a Potent Member of the Imipridone Class of Anti-Cancer Compounds That Induces p53-Independent Apoptosis in Hematological Malignancies

Free
Takenobu Nii, PhD, Jo Ishizawa, MD PhD, Ran Zhao, Jianfang Zeng, MD PhD, Dhruv Chachad, Kensuke Kojima, MD PhD, Marina Konopleva, MD PhD, Richard Eric Davis, MD, Joshua E Allen, PhD, Martin Stogniew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4059.
https://doi.org/10.1182/blood.V128.22.4059.4059
Published: 2016