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Journal Articles

Phase 1b Trial of Anti-Immunoglobulin-like Transcript 3 Monoclonal Antibody MK-0482 Monotherapy in Relapsed/Refractory Acute Myeloid Leukemia and Chronic Myelomonocytic Leukemia

Ghayas C. Issa, David Lavie, Amanda Przespolewski, Suraj Konnath George, Mo Huang, Mei Chen

Blood (2022) 140 (Supplement 1): 11759–11760.

https://doi.org/10.1182/blood-2022-169227

Published: 2022

Journal Articles

Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis

Yiqing Yang, Melanie Mumau, Joanna Tober, Qin Zhu, Laura Bennett, Courtney Hong, Derek Sung, Thomas Keller, Yasin Uzun, Peng Gao, Swapnil Shewale, Mei Chen, Jisheng Yang, Xiaowen Chen, Steven A. Thomas, Kai Tan, Nancy A. Speck, Mark L. Kahn

Blood (2022) 139 (19): 2942–2957.

https://doi.org/10.1182/blood.2021013934

Published: 2022

Includes: Supplemental data

Journal Articles

Subcutaneous Epcoritamab Induces Complete Responses with an Encouraging Safety Profile across Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Subtypes, Including Patients with Prior CAR-T Therapy: Updated Dose Escalation Data

Martin Hutchings, MD PhD, Rogier Mous, MD PhD, Michael Roost Clausen, MD PhD, Peter Johnson, MD FRCP, Kim M Linton, MBChB, PhD, Martine E.D. Chamuleau, MD PhD, David John Lewis, MD, Anna Sureda Balari, MD PhD, David Cunningham, MD FRCP, FMedSci, Roberto S Oliveri, MD PhD, Dena DeMarco, Brian Elliott, MD, Kuo-mei Chen, PhD, Pieternella J. Lugtenburg, MD PhD

Blood (2020) 136 (Supplement 1): 45–46.

https://doi.org/10.1182/blood-2020-133820

Published: 2020

Journal Articles

Hemostasis stimulates lymphangiogenesis through release and activation of VEGFC

Lillian Lim, Hung Bui, Olivia Farrelly, Jisheng Yang, Li Li, David Enis, Wanshu Ma, Mei Chen, Guillermo Oliver, John D. Welsh, Mark L. Kahn

Blood (2019) 134 (20): 1764–1775.

https://doi.org/10.1182/blood.2019001736

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Reduced Intensity Conditioned Bone Marrow Transplant with Post-Transplant Cyclophosphamide and Donor-Derived Mesenchymal Stromal Cell Infusions for Recessive Dystrophic Epidermolysis Bullosa

Christen L. Ebens, MD MPH, John A McGrath, MD FRCP, FMedSci, Katsuto Tamai, MD PhD, Hovnanian Alain, MD PhD, John E. Wagner, MD, Megan Riddle, Douglas R Keene, BS, Todd E. DeFor, MS, Rebecca Tryon, MS, Mei Chen, PhD, David T Woodley, MD, Kristin Hook, MD, Jakub L Tolar, MD PhD

Blood (2018) 132 (Supplement 1): 2165.

https://doi.org/10.1182/blood-2018-99-113035

Published: 2018

Journal Articles

Mucocutaneous Engraftment and Type VII Collagen (C7) Replacement after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Jakub Tolar, MD, PhD, John A McGrath, MD, Mark J. Osborn, PhD, Douglas R Keene, BS, Kristen Hook, MD, Maria Hordinsky, MD, David Woodley, MD, Mei Chen, PhD, Alain Hovnanian, MD PhD, Katsuto Tamai, MD PhD, Bruce R. Blazar, MD, John E Wagner, MD

Blood (2015) 126 (23): 402.

https://doi.org/10.1182/blood.V126.23.402.402

Published: 2015

Journal Articles

The Effect of the R882H DNMT3a Mutation on Megakaryocyte Cell Lines

Yang Lu, MD, Dan Wang, Yifang Yuan, Li mei Chen, Yi ke Huang, Hao Huang, MD, Kefeng Shen, MD, Yanyan Ye, Jing Sun, MD, Qianli Jiang, MD PhD

Blood (2014) 124 (21): 5186.

https://doi.org/10.1182/blood.V124.21.5186.5186

Published: 2014

Journal Articles

The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis

Zhiying Zou, David R. Enis, Hung Bui, Eugene Khandros, Vinayak Kumar, Zoltan Jakus, Christopher Thom, Yiqing Yang, Veerpal Dhillon, Mei Chen, MinMin Lu, Mitchell J. Weiss, Mark L. Kahn

Blood (2013) 121 (16): 3228–3236.

https://doi.org/10.1182/blood-2012-10-462689

Published: 2013

Includes: Supplemental data

Journal Articles

Bortezomib with Dexamethasone in Newly Diagnosed Patients with Primary Systemic Light Chain Amyloidosis or Multiple Myeloma-Associated AL Amyloidosis

Beihui Huang, M.D., Juan Li, MD, PhD, Junru Liu, M.D., Dong Zheng, MD, PhD, Mei Chen, M.D., Zhenhai Zhou, M.D., Duorong Xu, M.D., Waiyi Zou, M.D.

Blood (2012) 120 (21): 5036.

https://doi.org/10.1182/blood.V120.21.5036.5036

Published: 2012

Journal Articles

PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability

Yasuko Furumoto, Nicolas Charles, Ana Olivera, Wai Hang Leung, Sandra Dillahunt, Jennifer L. Sargent, Kevin Tinsley, Sandra Odom, Eric Scott, Todd M. Wilson, Kamran Ghoreschi, Manfred Kneilling, Mei Chen, David M. Lee, Silvia Bolland, Juan Rivera

Blood (2011) 118 (20): 5466–5475.

https://doi.org/10.1182/blood-2010-09-309955

Published: 2011

Includes: Supplemental data

Journal Articles

Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease

Alec A. Schmaier, Timothy J. Stalker, Jeffrey J. Runge, Dooyoung Lee, Chandrasekaran Nagaswami, Patricia Mericko, Mei Chen, Simon Cliché, Claude Gariépy, Lawrence F. Brass, Daniel A. Hammer, John W. Weisel, Karen Rosenthal, Mark L. Kahn

Blood (2011) 118 (13): 3661–3669.

https://doi.org/10.1182/blood-2011-02-338244

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Platelets regulate lymphatic vascular development through CLEC-2–SLP-76 signaling

Blood (2010) 116 (4): 661–670.

https://doi.org/10.1182/blood-2010-02-270876

Published: 2010

Includes: Supplemental data

Journal Articles

Synergistic Activity of Adenosine A2A and Beta-2 Adrenergic Receptor Agonists in Myeloma Cells in the Context of Tumor-Stromal Interactions

Douglas W. McMillin, PhD, Richard Rickles, Joseph Negri, Jake Delmore, Melissa G. Ooi, MD, Melissa Farwell, David Crowe, Mei Chen, William Avery, Vikram Kansra, PhD, Kenneth C. Anderson, MD, Margaret S. Lee, PhD, Constantine S. Mitsiades, MD, PhD

Blood (2008) 112 (11): 2663.

https://doi.org/10.1182/blood.V112.11.2663.2663

Published: 2008

Journal Articles

Preclinical Evaluation of CRx-501, a Potent Selective A2A Agonist as a Novel Drug Candidate for the Treatment of Multiple Myeloma

Richard J Rickles, Ph.D., Laura Pierce, Thomas Giordano, William Avery, Melissa Farwell, David Crowe, Winnie F. Tam, Ph.D., Mei Chen, Ph.D., Vikram Kansra, PhD, Douglas W. McMillin, BSc, PhD, Kenneth C Anderson, MD, Constantine Mitsiades, M.D., Ph.D., Margaret S. Lee, PhD

Blood (2008) 112 (11): 252.

https://doi.org/10.1182/blood.V112.11.252.252

Published: 2008

Journal Articles

Adenosine A2A and Beta-2 Adrenergic Receptor Agonism: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening

Richard J. Rickles, Ph.D., Laura Pierce, Thomas Giordano, Winnie F. Tam, Ph.D., William Avery, Melissa Farwell, David Crowe, Mei Chen, Ph.D., Alexander Brown, Vikram Kansra, PhD, Steffan T. Nawrocki, PhD, Jennifer S Carew, Ph.D., Francis J Giles, MD, Margaret S Lee, PhD

Blood (2008) 112 (11): 384.

https://doi.org/10.1182/blood.V112.11.384.384

Published: 2008

Journal Articles

BCL11B participates in the activation of IL2 gene expression in CD4 + T lymphocytes

Valeriu B. Cismasiu, Sailaja Ghanta, Javier Duque, Diana I. Albu, Hong-Mei Chen, Rohini Kasturi, Dorina Avram

Blood (2006) 108 (8): 2695–2702.

https://doi.org/10.1182/blood-2006-05-021790

Published: 2006

Includes: Supplemental data

Journal Articles

Cytogenetic Abnormalities Predict Disease Progression in Primary Myelodysplastic Syndrome: A Multicentric Study in 508 Chinese Patients.

Bing Chen, Wei-Li Zhao, Jie Jin, Yong-Quan Xue, Xin Cheng, Xiao-Ting Chen, Jing Cui, Zhi-Mei Chen, Qi Cao, Guang Yang, Ying Yao, Jian-Hua Tong, Jun-Min Li, Jue Chen, Shu-Min Xiong, Zhi-Xiang Shen, Zhu Chen, Sai-Juan Chen

Blood (2004) 104 (11): 1451.

https://doi.org/10.1182/blood.V104.11.1451.1451

Published: 2004

Journal Articles

Blockage of the Early Events of Mitogenic Signaling by Interferon-γ in Macrophages in Response to Colony-Stimulating Factor-1

Jianhua Xu, Steven Kim, Mei Chen, Shayna Rockow, Soyun Elizabeth Yi, Andrew J. Wagner, Nissim Hay, Ralph R. Weichselbaum, Wei Li

Blood (1995) 86 (7): 2774–2788.

https://doi.org/10.1182/blood.V86.7.2774.2774

Published: 1995

NARROW

Phase 1b Trial of Anti-Immunoglobulin-like Transcript 3 Monoclonal Antibody MK-0482 Monotherapy in Relapsed/Refractory Acute Myeloid Leukemia and Chronic Myelomonocytic Leukemia

Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis

Subcutaneous Epcoritamab Induces Complete Responses with an Encouraging Safety Profile across Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Subtypes, Including Patients with Prior CAR-T Therapy: Updated Dose Escalation Data

Hemostasis stimulates lymphangiogenesis through release and activation of VEGFC

Reduced Intensity Conditioned Bone Marrow Transplant with Post-Transplant Cyclophosphamide and Donor-Derived Mesenchymal Stromal Cell Infusions for Recessive Dystrophic Epidermolysis Bullosa

Mucocutaneous Engraftment and Type VII Collagen (C7) Replacement after Allogeneic Hematopoietic Cell Transplantation (HCT) in Patients with Recessive Dystrophic Epidermolysis Bullosa (RDEB)

The Effect of the R882H DNMT3a Mutation on Megakaryocyte Cell Lines

The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis

Bortezomib with Dexamethasone in Newly Diagnosed Patients with Primary Systemic Light Chain Amyloidosis or Multiple Myeloma-Associated AL Amyloidosis

PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability

Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease

Platelets regulate lymphatic vascular development through CLEC-2–SLP-76 signaling

Synergistic Activity of Adenosine A2A and Beta-2 Adrenergic Receptor Agonists in Myeloma Cells in the Context of Tumor-Stromal Interactions

Preclinical Evaluation of CRx-501, a Potent Selective A2A Agonist as a Novel Drug Candidate for the Treatment of Multiple Myeloma

Adenosine A2A and Beta-2 Adrenergic Receptor Agonism: Novel Selective and Synergistic Multiple Myeloma Targets Discovered through Systematic Combination Screening

BCL11B participates in the activation of IL2 gene expression in CD4 + T lymphocytes

Cytogenetic Abnormalities Predict Disease Progression in Primary Myelodysplastic Syndrome: A Multicentric Study in 508 Chinese Patients.

Blockage of the Early Events of Mitogenic Signaling by Interferon-γ in Macrophages in Response to Colony-Stimulating Factor-1

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American Society of Hematology

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American Society of Hematology

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