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Neil L. Kelleher
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Journal Articles

Development of First-in-Class Histone Acetyltransferase (HAT) Activators for Precision Targeting of Epigenetic Derangements in Lymphoma

Yuxuan Liu, PhD, Jole Fiorito, PhD, Yulissa Gonzalez, Elisa Zuccarello, PhD, Elisa Calcagno, Adolfo Mazzeo, Nebiyu Ali Abshiru, PhD, Jeannie Camarillo, PhD, Neil L Kelleher, PhD, Changhong Qiao, Renu Nandakumar, PhD, Cremers Serge, PhD PharmD, Shixian Deng, PhD, Donald Landry, MD PhD, Owen A. O'Connor, MD, PhD, Ottavio Arancio, PhD, Jennifer E Amengual, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 37.
https://doi.org/10.1182/blood-2018-99-110447
Published: 2018
Journal Articles

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Te Ling, PhD, Yehudit Birger, PhD, Monika Stankiewicz, PhD, Nissim Ben-Haim, Itamar Kanter, Tomer Kalisky, Avigail Rein Gil, MD, Neil L Kelleher, PhD, Lihua Zou, PhD, Shai Izraeli, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2018) 132 (Supplement 1): 533.
https://doi.org/10.1182/blood-2018-99-115338
Published: 2018
Journal Articles

Therapeutic Targeting of the Histone Ubiquitination-Methylation Axis in T Cell Leukemia

Panagiotis Ntziachristos, PhD, Kelly Arcipowski, PhD, Carlos Alberto Martinez, Yixing Zhu, Andrew G. Volk, PhD, Suresh Kumar, Paul M Thomas, PhD, Pieter Van Vlierberghe, PhD, Nobuko Hijiya, MD, Stacy Marshall, Jack Wang, Jian Wu, Neil L Kelleher, PhD, John Crispino, PhD MBA
Journal: Blood
Blood (2016) 128 (22): 1532.
https://doi.org/10.1182/blood.V128.22.1532.1532
Published: 2016
Journal Articles

Allele-Specific Crispr Targeting Reveals Epigenetic and Phenotypic Effects of a MMSET Gain of Function Mutation Found in Relapsed Acute Lymphoblastic Leukemia

Jon Oyer, PhD, Christine Will, M.S., Xiaoxiao Huang, Teresa Ezponda, PhD, Relja Popovic, PhD, Yupeng Zheng, PhD, Neil L Kelleher, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2015) 126 (23): 437.
https://doi.org/10.1182/blood.V126.23.437.437
Published: 2015
Journal Articles

BAP1 Loss Results in EZH2-Dependent Transformation in Myelodysplastic Syndromes

Lindsay M LaFave, PhD, Wendy Béguelin, PhD, Richard Koche, PhD, Matt Teater, Efthymia Papalexi, Barbara Spitzer, MD, Sarah Knutson, PhD, John Campbell, PhD, Heike Keilhack, PhD, Paul M Thomas, PhD, Neil L Kelleher, PhD, Omar Abdel-Wahab, Ari M. Melnick, MD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD
Journal: Blood
Blood (2015) 126 (23): 713.
https://doi.org/10.1182/blood.V126.23.713.713
Published: 2015
Journal Articles

Loss of the Histone Demethylase UTX Contributes to Multiple Myeloma and Sensitizes Cells to EZH2 Inhibitors

Teresa Ezponda, PhD, Relja Popovic, PhD, Yupeng Zheng, PhD, Behnam Nabet, Christine Will, MS, Eliza C Small, PhD, Manuela Occhionorelli, PhD, Giovanni Tonon, MDPhD, Jonathan J. Keats, PhD, Neil L Kelleher, PhD, Jonathan D. Licht
Journal: Blood
Blood (2014) 124 (21): 611.
https://doi.org/10.1182/blood.V124.21.611.611
Published: 2014
Journal Articles

MMSET Contributes to Multiple Myeloma Oncogenesis Through Induction of Global Epigenetic Changes and Alteration of the DNA Damage Response,

Relja Popovic, PhD, Eva Martinez-Garcia, PhD, Steve M.M Sweet, PhD, Yupeng Zheng, PhD, Neil L Kelleher, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2011) 118 (21): 3475.
https://doi.org/10.1182/blood.V118.21.3475.3475
Published: 2011
Journal Articles

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

Eva Martinez-Garcia, Relja Popovic, Dong-Joon Min, Steve M. M. Sweet, Paul M. Thomas, Leonid Zamdborg, Aaron Heffner, Christine Will, Laurence Lamy, Louis M. Staudt, David L. Levens, Neil L. Kelleher, Jonathan D. Licht
Journal: Blood
Blood (2011) 117 (1): 211–220.
https://doi.org/10.1182/blood-2010-07-298349
Published: 2011
Includes: Supplemental data