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Journal Articles

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

Brian A. Walker, Paola E. Leone, Laura Chiecchio, Nicholas J. Dickens, Matthew W. Jenner, Kevin D. Boyd, David C. Johnson, David Gonzalez, Gian Paolo Dagrada, Rebecca K. M. Protheroe, Zoe J. Konn, David M. Stockley, Walter M. Gregory, Faith E. Davies, Fiona M. Ross, Gareth J. Morgan

Blood (2010) 116 (15): e56–e65.

https://doi.org/10.1182/blood-2010-04-279596

Published: 2010

Includes: Supplemental data

Journal Articles

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

Tina Bagratuni, Ping Wu, David Gonzalez de Castro, Emma L. Davenport, Nicholas J. Dickens, Brian A. Walker, Kevin Boyd, David C. Johnson, Walter Gregory, Gareth J. Morgan, Faith E. Davies

Blood (2010) 116 (2): 250–253.

https://doi.org/10.1182/blood-2010-01-263236

Published: 2010

Journal Articles

Molecular Characterization of Human Multiple Myeloma Cell Lines by Genome-Wide Profiling.

Carolina Elosua, Purificacion Catalina, Cristina Palma, PhD, Brian A Walker, PhD, Nicholas J Dickens, DPhil, David Gonzalez, PhD, Faith E Davies, MD, Gareth J Morgan, Paola E. Leone, PhD

Blood (2009) 114 (22): 1793.

https://doi.org/10.1182/blood.V114.22.1793.1793

Published: 2009

Journal Articles

UTX , a Histone Demethylase, Is Inactivated through Homozygous Deletion, Mutation, and DNA Methylation in Multiple Myeloma.

Brian A Walker, PhD, Paola E. Leone, PhD, Nicholas J Dickens, DPhil, Kevin D Boyd, MB.BS, David Gonzalez, PhD, Faith E Davies, MD, Gareth J Morgan

Blood (2009) 114 (22): 1798.

https://doi.org/10.1182/blood.V114.22.1798.1798

Published: 2009

Journal Articles

Gene Expression Profiling Classifies Splenic Marginal Zone Lymphoma and Hairy Cell Leukemia-Variant as Related Diseases That Are Distinct From Typical Hairy Cell Leukemia.

Sarah L Hockley, PhD, Alison Morilla, Andrew Wotherspoon, MD, PhD, Brian A Walker, PhD, Nicholas J Dickens, PhD, Daniel Catovsky, MD, DSc(Med), Gareth J Morgan, MD, PhD, Estella Matutes, MD, PhD, David Gonzalez, PhD

Blood (2009) 114 (22): 3467.

https://doi.org/10.1182/blood.V114.22.3467.3467

Published: 2009

Journal Articles

Genetic Variations Associated with Overall and Progression-Free Survival in Multiple Myeloma Patients Treated with Thalidomide Combinations.

David C Johnson, BSc, Walter M Gregory, PhD, Nicholas J Dickens, DPhil, Brian A Walker, PhD, Alex J Szubert, MSc, Faith E Davies, MD, Brian G M Durie, MD, Brian G Van Ness, PhD, Gareth J Morgan, MD, PhD

Blood (2009) 114 (22): 426.

https://doi.org/10.1182/blood.V114.22.426.426

Published: 2009

Journal Articles

Global Methylation Array Analysis of Multiple Myeloma Samples Indicate An Alteration of Epigenetics During the Transition From MGUS to Myeloma and An Increased Frequency of Gene Methylation in t(4;14) Myeloma.

Brian A Walker, PhD, Emma M Smith, PhD, Nicholas J Dickens, DPhil, Fiona M Ross, DPhil, Faith E Davies, MD, Gareth J Morgan

Blood (2009) 114 (22): 121.

https://doi.org/10.1182/blood.V114.22.121.121

Published: 2009

Journal Articles

Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping

David C. Johnson, Sophie Corthals, Christine Ramos, Antje Hoering, Kim Cocks, Nicholas J. Dickens, Jeff Haessler, Harmut Goldschmidt, J. Anthony Child, Sue E. Bell, Graham Jackson, Dalsu Baris, S. Vincent Rajkumar, Faith E. Davies, Brian G. M. Durie, John Crowley, Pieter Sonneveld, Brian Van Ness, Gareth J. Morgan

Blood (2008) 112 (13): 4924–4934.

https://doi.org/10.1182/blood-2008-02-140434

Published: 2008

Includes: Supplemental data

Journal Articles

Homozygous Deletions Can Be Used to Define a Cell Death Specific Gene Expression Signature Able to Predict Outcome in Myeloma

Nicholas J Dickens, DPhil, Brian Walker, PhD, Paola E Leone, PhD, Matthew W Jenner, Faith Davies, MD, Gareth J Morgan, MD, PhD

Blood (2008) 112 (11): 2725.

https://doi.org/10.1182/blood.V112.11.2725.2725

Published: 2008

Journal Articles

Molecular Characterization of Human Multiple Myeloma Cell Lines by Genome-Wide Profiling Identifies Kinase Pathway Alterations.

Carolina Elosua, Purificacion Catalina, Brian A Walker, Nicholas J Dickens, Athanasia Avramidou, Luis Brito, Emma Davenport, PhD, Matthew W Jenner, David Gonzalez, PhD, Faith Davies, MD, Gareth J Morgan, MD, PhD, Paola E Leone, PhD

Blood (2008) 112 (11): 1694.

https://doi.org/10.1182/blood.V112.11.1694.1694

Published: 2008

Journal Articles

High Resolution Genomic Profiling Using Single Nucleotide Polymorphism Microarrays Identifies Multiple Novel Genomic Minimally Deleted Regions in Multiple Myeloma

Brian A WalKer, PhD, Paola E Leone, PhD, Nicholas J Dickens, DPhil, Matthew W Jenner, MD, Laura Chiecchio, GianPaolo Dagrada, Fiona M Ross, DPhil, Faith E Davies, MD, Gareth J Morgan, MD, PhD

Blood (2008) 112 (11): 625.

https://doi.org/10.1182/blood.V112.11.625.625

Published: 2008

Journal Articles

The Impact of Constitutional Copy Number Variants in Myeloma

Matthew W Jenner, David C Johnson, Paola E Leone, Brian A Walker, David Gonzalez, Nicholas J Dickens, Faith E Davies, Gareth J. Morgan

Blood (2008) 112 (11): 496.

https://doi.org/10.1182/blood.V112.11.496.496

Published: 2008

Journal Articles

An Integrated Pharmacogenomic Strategy for the Definition of Thalidomide Response Signatures in Presenting Cases of Multiple Myeloma.

Gareth J. Morgan, MD, PhD, Matthew W. Jenner, MD, Brian A. Walker, PhD, David C. Johnson, BSc, Paola A. Leone, PhD, Fiona M. Ross, PhD, Mark T. Drayson, MD, PhD, Brian G. Van Ness, Brian G. Durie, Nicholas J. Dickens, PhD, J. Anthony Child, R.G. Owen, Faith E. Davies, MD

Blood (2007) 110 (11): 2493.

https://doi.org/10.1182/blood.V110.11.2493.2493

Published: 2007

Journal Articles

Genome-Wide Identification of Gene Expression Networks Affected by Genomic Changes in Multiple Myeloma.

Nicholas J. Dickens, DPhil, Paola E. Leone, PhD, Brian A. Walker, PhD, Matthew W. Jenner, MD, Faith E. Davies, MD, Gareth J. Morgan, MD, PhD

Blood (2007) 110 (11): 2494.

https://doi.org/10.1182/blood.V110.11.2494.2494

Published: 2007

Journal Articles

Integration of Gene Mapping and Expression Arrays Identifies Mechanisms by Which Genes Are Dysregulated as a Result of Copy Number Loss and Gain Associated with IgH Translocations in Multiple Myeloma.

Matthew W. Jenner, MD, Gonzalez David, PhD, Paola E. Leone, PhD, Brian A. Walker, PhD, David C. Johnson, BSc, Nicholas J. Dickens, PhD, Fiona M. Ross, PhD, Faith E. Davies, MD, Gareth J. Morgan, MD, PhD

Blood (2007) 110 (11): 395.

https://doi.org/10.1182/blood.V110.11.395.395

Published: 2007

Journal Articles

Mutation and Methylation Analysis of WWOX and CYLD on 16q; Potential Tumor Suppressor Genes in Myeloma.

Brian A. Walker, PhD, Matthew W. Jenner, MD, Poala E. Leone, PhD, Nicholas J. Dickens, DPhil, David C. Johnson, BSc, Fiona M. Ross, DPhil, Faith E. Davies, MD, Gareth J. Morgan, MD, PhD

Blood (2007) 110 (11): 2473.

https://doi.org/10.1182/blood.V110.11.2473.2473

Published: 2007

Journal Articles

Screening of Homozygous Deletions Identifies Key Deregulated Genes and Pathways in Multiple Myeloma.

Paola E. Leone, PhD, Brian A. Walker, PhD, Nicholas J. Dickens, DPhil, Matthew W. Jenner, MD, David C. Johnson, BSc, Fiona M. Ross, DPhil, Faith E. Davies, MD, Gareth J. Morgan, MD, PhD

Blood (2007) 110 (11): 2474.

https://doi.org/10.1182/blood.V110.11.2474.2474

Published: 2007

Journal Articles

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

Matthew W. Jenner, Paola E. Leone, Brian A. Walker, Fiona M. Ross, David C. Johnson, David Gonzalez, Laura Chiecchio, Elisabet Dachs Cabanas, Gian Paolo Dagrada, Mathew Nightingale, Rebecca K. M. Protheroe, David Stockley, Monica Else, Nicholas J. Dickens, Nicholas C. P. Cross, Faith E. Davies, Gareth J. Morgan

Blood (2007) 110 (9): 3291–3300.

https://doi.org/10.1182/blood-2007-02-075069

Published: 2007

Includes: Supplemental data

NARROW

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

Molecular Characterization of Human Multiple Myeloma Cell Lines by Genome-Wide Profiling.

UTX , a Histone Demethylase, Is Inactivated through Homozygous Deletion, Mutation, and DNA Methylation in Multiple Myeloma.

Gene Expression Profiling Classifies Splenic Marginal Zone Lymphoma and Hairy Cell Leukemia-Variant as Related Diseases That Are Distinct From Typical Hairy Cell Leukemia.

Genetic Variations Associated with Overall and Progression-Free Survival in Multiple Myeloma Patients Treated with Thalidomide Combinations.

Global Methylation Array Analysis of Multiple Myeloma Samples Indicate An Alteration of Epigenetics During the Transition From MGUS to Myeloma and An Increased Frequency of Gene Methylation in t(4;14) Myeloma.

Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping

Homozygous Deletions Can Be Used to Define a Cell Death Specific Gene Expression Signature Able to Predict Outcome in Myeloma

Molecular Characterization of Human Multiple Myeloma Cell Lines by Genome-Wide Profiling Identifies Kinase Pathway Alterations.

High Resolution Genomic Profiling Using Single Nucleotide Polymorphism Microarrays Identifies Multiple Novel Genomic Minimally Deleted Regions in Multiple Myeloma

The Impact of Constitutional Copy Number Variants in Myeloma

An Integrated Pharmacogenomic Strategy for the Definition of Thalidomide Response Signatures in Presenting Cases of Multiple Myeloma.

Genome-Wide Identification of Gene Expression Networks Affected by Genomic Changes in Multiple Myeloma.

Integration of Gene Mapping and Expression Arrays Identifies Mechanisms by Which Genes Are Dysregulated as a Result of Copy Number Loss and Gain Associated with IgH Translocations in Multiple Myeloma.

Mutation and Methylation Analysis of WWOX and CYLD on 16q; Potential Tumor Suppressor Genes in Myeloma.

Screening of Homozygous Deletions Identifies Key Deregulated Genes and Pathways in Multiple Myeloma.

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

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American Society of Hematology

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American Society of Hematology

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