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Journal Articles

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Johann-Christoph Jann, Johanna Flach, PhD, Antje Knaflic, Eva Altrock, PhD, Nanni Schmitt, MSc, Alexander Streuer, Justine Danner, Franziska Hofmann, Verena Nowak, Nina Draeger, Julia Obländer, Iris Palme, Patrick Wuchter, MD, Ahmed Jawhar, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, MD PhD, Daniel Nowak, MD

Blood (2019) 134 (Supplement_1): 4218.

https://doi.org/10.1182/blood-2019-126431

Published: 2019

Journal Articles

Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

Ruben A. Gößmann, Lei Wang, MD, Ming Ni, Mingya Yang, MD, Thomas Luft, Ute Hegenbart, MD, Stefan O. Schönland, MD, Patrick Wuchter, MD, Volker Eckstein, William Hermann Krüger, MD PhD, Ronit Yerushalmi, MD, Katia Beider, Arnon Nagler, MD MSc, Carsten Müller-Tidow, MD, Peter Dreger, Michael Schmitt, MD, Anita Schmitt, MD

Blood (2019) 134 (Supplement_1): 3287.

https://doi.org/10.1182/blood-2019-125049

Published: 2019

Journal Articles

No Inhibition of Anti-Viral and Anti-Leukemia Effects By Extracorporeal Photopheresis Therapy

Blood (2018) 132 (Supplement 1): 3399.

https://doi.org/10.1182/blood-2018-99-113277

Published: 2018

Journal Articles

Cohesin Subunit SMC3 Levels Impact on Karyotype and Outcome in Acute Myeloid Leukemia

Bianca Kraft, PhD, Jan Lombard, Michael Kirsch, Patrick Wuchter, MD, Peter Bugert, MD, Thomas Hielscher, Norbert Blank, MD, Alwin Kraemer, MD

Blood (2018) 132 (Supplement 1): 2786.

https://doi.org/10.1182/blood-2018-99-118454

Published: 2018

Journal Articles

Biomarkers for Clinical Response of Extracorporeal Photopheresis

Blood (2017) 130 (Supplement 1): 3264.

https://doi.org/10.1182/blood.V130.Suppl_1.3264.3264

Published: 2017

Journal Articles

Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDH mut -Driven DNA Hypermethylation in AML Stem Cells

Blood (2017) 130 (Supplement 1): 472.

https://doi.org/10.1182/blood.V130.Suppl_1.472.472

Published: 2017

Journal Articles

Chemotherapy-Based Stem Cell Mobilization Does Not Result in Significant Paraprotein Reduction in Myeloma Patients in the Era of Novel Induction Regimens

Anthony Oyekunle, MD FMCPath, Evgenii Shumilov, MD, Philippe Kostrewa, Andreas Burchert, MD, Patrick Wuchter, MD, Ulrike Bacher, MD, Gerald Wulf, MD, Nicolaus Kroeger, MD Prof

Blood (2016) 128 (22): 2176.

https://doi.org/10.1182/blood.V128.22.2176.2176

Published: 2016

Journal Articles

Evaluation of Stem Cell Mobilization in Patients with Multiple Myeloma after Lenalidomide-Based Induction Chemotherapy within the GMMG-HD6 Trial

Blood (2016) 128 (22): 3373.

https://doi.org/10.1182/blood.V128.22.3373.3373

Published: 2016

Journal Articles

Marked Impact of Different Cytokines on Phenotype and Cytotoxic Activity of CD19-Specific CAR T Cells

Jean-Marc Hoffmann, Lei Wang, Angela Hückelhoven, PhD, Anita Schmitt, MD, Ulrike Gern, Leopold Sellner, MD, Christian Kleist, PhD, Jessica Wenthe, Patrick Wuchter, MD, Maria-Luisa Schubert, MD, Hyeon Joo Yoo, Ming Ni, Susanne Hofmann, MD, Peter Dreger, MD, Anthony D. Ho, MD, Angelica Loskog, PhD, Michael Schmitt, MD

Blood (2016) 128 (22): 3509.

https://doi.org/10.1182/blood.V128.22.3509.3509

Published: 2016

Journal Articles

Peptide Vaccination Against Cytomegalovirus (CMV) Elicits Immunological and Clinical Responses after Allogeneic Stem Cell Transplantation Even from a CMV Seronegative Donor

Blood (2016) 128 (22): 2519.

https://doi.org/10.1182/blood.V128.22.2519.2519

Published: 2016

Journal Articles

A Single Center Comparison Between Two Different Apheresis Systems for Peripheral Blood Stem Cell Collections

Katharina Lisenko, MD, Thomas Bruckner, PhD, Michael Hundemer, MD, Anita Schmitt, MD, Joe Puthenparambil, MD, Petra Pavel, MD, Jens Hillengass, MD, Mathias Witzens-Harig, MD, Hartmut Goldschmidt, MD, Anthony D Ho, MD, Patrick Wuchter, MD

Blood (2015) 126 (23): 1900.

https://doi.org/10.1182/blood.V126.23.1900.1900

Published: 2015

Journal Articles

Validation of a Predictive Formula for Collection of Hematopoietic Progenitor Cells (HPC) By Leukapheresis at 2 Institutions Using 4 Different Machine Protocols

Eric R Rosenbaum, MD MPH, Patrick Wuchter, MD, Michael Hundemer, MD, Petra Pavel, MD, Mathias Witzens-Harig, MD, Hartmut Goldschmidt, MD, Bart Barlogie, MD PhD, Anthony Ho, MD, Michele H. Cottler-Fox, MD

Blood (2014) 124 (21): 2458.

https://doi.org/10.1182/blood.V124.21.2458.2458

Published: 2014

Journal Articles

Understanding The Marrow Niche: Advanced 3D Model System Allows Functional Analysis Of The Interaction With Human Hematopoietic Progenitor Cells

Patrick Wuchter, MD, Rainer Saffrich, PhD, Stefan Giselbrecht, PhD, Patrick Horn, PhD, Anthony D. Ho, MD, Eric Gottwald, PhD

Blood (2013) 122 (21): 2462.

https://doi.org/10.1182/blood.V122.21.2462.2462

Published: 2013

Journal Articles

Plerixafor Abrogates the Supportive Function of MSC for Self-Renewal of Human Hematopoietic Stem Cells,

Annette Ludwig, Rainer Saffrich, PhD, Volker Eckstein, PhD, Angela Lenze, Anke Diehlmann, Anthony D. Ho, MD, Patrick Wuchter, MD

Blood (2011) 118 (21): 3408.

https://doi.org/10.1182/blood.V118.21.3408.3408

Published: 2011

Journal Articles

Novel 3D-Model for the Hematopoietic Stem Cell Niche Using MSC in a KITChip Based Bioreactor

Patrick Wuchter, MD, Rainer Saffrich, PhD, Stefan Giselbrecht, PhD, Anthony D. Ho, MD, Eric Gottwald, PhD

Blood (2011) 118 (21): 1331.

https://doi.org/10.1182/blood.V118.21.1331.1331

Published: 2011

Journal Articles

Frequency of Leukemia Stem Cell Candidates Predicts Refractoriness to Conventional Chemotherapy and Adverse Clinical Outcome

Dan Ran, MD, Isabel Taubert, Volker Eckstein, PhD, Frauke Bellos, MD, Patrick Wuchter, MD, Rainer Saffrich, PhD, Mario Schubert, MD, Anthony D. Ho, MD, FRCPC

Blood (2010) 116 (21): 2160.

https://doi.org/10.1182/blood.V116.21.2160.2160

Published: 2010

Journal Articles

Cellular Interaction Between Human Mesenchymal Stem Cells and Hematopoietic Stem Cells in 2D- and 3D-Culture-Systems.

Patrick Wuchter, MD, Rainer Saffrich, PhD, Annette Ludwig, Mario Schubert, MD, Volker Eckstein, PhD, Anthony D. Ho, MD, PhD

Blood (2009) 114 (22): 1442.

https://doi.org/10.1182/blood.V114.22.1442.1442

Published: 2009

Journal Articles

Molecular Determinants and Functional Characteristics of Leukemic Stem Cells and Their Interaction with the Niche.

Dan Ran, Isabel Taubert, Larissa Pietsch, Patrick Wuchter, MD, Isabelle Hellwig, Rainer Saffrich, PhD, Volker Eckstein, PhD, Anthony D. Ho, MD, PhD and, Mario Schubert, MD

Blood (2009) 114 (22): 1427.

https://doi.org/10.1182/blood.V114.22.1427.1427

Published: 2009

Journal Articles

Comparative in-Vitro Evaluation of the Myeloid Toxicity of Pentostatin and the Novel PNP-Inhibitor Forodesine.

Mario Schubert, MD, Christian Wallenwein, Larissa Pietsch, Dan Ran, Isabel Taubert, Katrin Miesala, Patrick Wuchter, MD, Volker Eckstein, PhD, Anthony D. Ho, MD, PhD

Blood (2009) 114 (22): 3766.

https://doi.org/10.1182/blood.V114.22.3766.3766

Published: 2009

Journal Articles

Poor Mobilization of Hematopoietic Stem Cells – Definitions, Incidence, Risk Factors and Impact On Outcome of Autologous Transplantation.

Patrick Wuchter, MD, Dan Ran, Thomas Schmitt, MD, Tom Bruckner, PhD, Mathias Witzens-Harig, MD, Hartmut Goldschmidt, MD, Anthony D. Ho, MD, PhD

Blood (2009) 114 (22): 2153.

https://doi.org/10.1182/blood.V114.22.2153.2153

Published: 2009

NARROW

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

No Inhibition of Anti-Viral and Anti-Leukemia Effects By Extracorporeal Photopheresis Therapy

Cohesin Subunit SMC3 Levels Impact on Karyotype and Outcome in Acute Myeloid Leukemia

Biomarkers for Clinical Response of Extracorporeal Photopheresis

Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDH mut -Driven DNA Hypermethylation in AML Stem Cells

Chemotherapy-Based Stem Cell Mobilization Does Not Result in Significant Paraprotein Reduction in Myeloma Patients in the Era of Novel Induction Regimens

Evaluation of Stem Cell Mobilization in Patients with Multiple Myeloma after Lenalidomide-Based Induction Chemotherapy within the GMMG-HD6 Trial

Marked Impact of Different Cytokines on Phenotype and Cytotoxic Activity of CD19-Specific CAR T Cells

Peptide Vaccination Against Cytomegalovirus (CMV) Elicits Immunological and Clinical Responses after Allogeneic Stem Cell Transplantation Even from a CMV Seronegative Donor

A Single Center Comparison Between Two Different Apheresis Systems for Peripheral Blood Stem Cell Collections

Validation of a Predictive Formula for Collection of Hematopoietic Progenitor Cells (HPC) By Leukapheresis at 2 Institutions Using 4 Different Machine Protocols

Understanding The Marrow Niche: Advanced 3D Model System Allows Functional Analysis Of The Interaction With Human Hematopoietic Progenitor Cells

Plerixafor Abrogates the Supportive Function of MSC for Self-Renewal of Human Hematopoietic Stem Cells,

Novel 3D-Model for the Hematopoietic Stem Cell Niche Using MSC in a KITChip Based Bioreactor

Frequency of Leukemia Stem Cell Candidates Predicts Refractoriness to Conventional Chemotherapy and Adverse Clinical Outcome

Cellular Interaction Between Human Mesenchymal Stem Cells and Hematopoietic Stem Cells in 2D- and 3D-Culture-Systems.

Molecular Determinants and Functional Characteristics of Leukemic Stem Cells and Their Interaction with the Niche.

Comparative in-Vitro Evaluation of the Myeloid Toxicity of Pentostatin and the Novel PNP-Inhibitor Forodesine.

Poor Mobilization of Hematopoietic Stem Cells – Definitions, Incidence, Risk Factors and Impact On Outcome of Autologous Transplantation.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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