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Paul Sims
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Journal Articles

Pharmacokinetic and Pharmacodynamic Study of NKTR-255, a Polymer-Conjugated Human IL-15, in Cynomolgus Monkey

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Takahiro Miyazaki, Peiwen Kuo, Mekhala Maiti, Palakshi Obalapur, Murali Addepalli, Werner Rubas, Paul Sims, Ping Zhang, Mario Q. Marcondes, MD PhD, Loui Madakamutil, Jonathan Zalevsky
Journal: Blood
Blood (2018) 132 (Supplement 1): 2952.
https://doi.org/10.1182/blood-2018-99-115638
Published: 2018
Journal Articles

Dose Finding in Human Trials of TLR9 Agonists: Induction of Interferon-α Inducible Genes in Blood Mononuclear Cells as a Measure of Biologic Activity of 1018 ISS.

Free
James N. Lowder, MD, Jonathan W. Freidberg, MD, Jennifer Kelly, Arnold S. Freedman, MD, Robert Coffman, PhD, Holger Kanzler, PhD, Paul Sims, Jimmy Hwang, MD, Nicholas Haining
Journal: Blood
Blood (2007) 110 (11): 3844.
https://doi.org/10.1182/blood.V110.11.3844.3844
Published: 2007
Journal Articles

Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-α/β–inducible gene expression, without significant toxicity

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Clinical Trials & Observations
Jonathan W. Friedberg, Helen Kim, Mary McCauley, Edith M. Hessel, Paul Sims, David C. Fisher, Lee M. Nadler, Robert L. Coffman, Arnold S. Freedman
Journal: Blood
Blood (2005) 105 (2): 489–495.
https://doi.org/10.1182/blood-2004-06-2156
Published: 2005