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Journal Articles

Thrombosis risk in single- and double-heterozygous carriers of factor V Leiden and prothrombin G20210A in FinnGen and the UK Biobank

Justine Ryu, Joel T. Rämö, Sean J. Jurgens, Teemu Niiranen, Simone Sanna-Cherchi, Kenneth A. Bauer, Amelia Haj, Seung Hoan Choi, Aarno Palotie, Mark Daly, Patrick T. Ellinor, Pavan K. Bendapudi

Blood (2024) 143 (23): 2425–2432.

https://doi.org/10.1182/blood.2023023326

Published: 2024

Includes: Supplemental data

Journal Articles

Low-frequency inherited complement receptor variants are associated with purpura fulminans

Blood (2024) 143 (11): 1032–1044.

https://doi.org/10.1182/blood.2023021231

Published: 2024

Includes: Supplemental data

Journal Articles

Coagulation Factor XII ( F12 ) Haploinsufficiency Is Protective Against Venous Thromboembolism in 415,921 Individuals

Amelia K Haj, Justine Ryu, Satoshi Koyama, Sean J. Jurgens, Xin Wang, Seung Hoan Choi, Sharjeel Chaudhry, Simone Sanna-Cherchi, Steven P Grover, Patrick Ellinor, Pavan K Bendapudi

Blood (2023) 142 (Supplement 1): 805.

https://doi.org/10.1182/blood-2023-189823

Published: 2023

Journal Articles

Clinical Consequences of Rare Germline Variation in Genes Associated with Coagulation across 451,958 Individuals

Justine Ryu, Amelia K Haj, Satoshi Koyama, Sean J. Jurgens, Simone Sanna-Cherchi, Patrick Ellinor, Pavan K Bendapudi

Blood (2023) 142 (Supplement 1): 3972.

https://doi.org/10.1182/blood-2023-186786

Published: 2023

Journal Articles

Protein Z ( PROZ ) Loss of Function Is Associated with Increased Risk of Ischemic Stroke in 416,767 UK Biobank Participants

Amelia K Haj, Sean J. Jurgens, Xin Wang, Justine Ryu, Seung Hoan Choi, Simone Sanna-Cherchi, Patrick Ellinor, Pavan K Bendapudi

Blood (2023) 142 (Supplement 1): 2611.

https://doi.org/10.1182/blood-2023-182861

Published: 2023

Journal Articles

Meta-Analysis of National-Level Genotyping Datasets to Determine the Risk of Thrombosis in Double Heterozygous Carriers of Factor V Leiden and the Prothrombin G20210A Mutation across 876,417 Individuals

Justine Ryu, Joel Rämö, Sean J. Jurgens, Teemu Niiranen, Aarno Palotie, Mark Daly, Simone Sanna-Cherchi, Patrick Ellinor, Kenneth A Bauer, Pavan K Bendapudi

Blood (2023) 142 (Supplement 1): 806.

https://doi.org/10.1182/blood-2023-187105

Published: 2023

Journal Articles

Determinants and Clinical Impact of Time to Plasma Exchange in Patients with Immune Thrombotic Thrombocytopenic Purpura

Ishan J Tatake, Shelby C Wilkinson, Kristen N Ruby, Julia N Collins, Walter Dzik, Lynne Uhl, Richard M Kaufman, Brian J Carney, Robert Makar, Pavan K Bendapudi

Blood (2023) 142 (Supplement 1): 4004.

https://doi.org/10.1182/blood-2023-182251

Published: 2023

Journal Articles

Association between Hereditary Angioedema and Venous Thromboembolism in a Large Population-Based Case-Control Study

Linda Sundler Bjorkman, Alexandru Dregan, Harish Eswaran, Bengt Zoller, Pavan K Bendapudi, Prakash Saha, Steven P Grover

Blood (2023) 142 (Supplement 1): 1266.

https://doi.org/10.1182/blood-2023-174693

Published: 2023

Journal Articles

Rare Germline Loss-of-Function Variants in HSP47 ( SERPINH1 ) Are Associated with an Intermediate Osteogenesis Imperfecta Phenotype Characterized By Atopic Inflammation and Increased Risk of Thrombosis

Amelia K Haj, Sean J. Jurgens, Xin Wang, Justine Ryu, Seung Hoan Choi, Steven P Grover, Simone Sanna-Cherchi, Alec A Schmaier, Patrick Ellinor, Pavan K Bendapudi

Blood (2023) 142 (Supplement 1): 3934.

https://doi.org/10.1182/blood-2023-189896

Published: 2023

Journal Articles

C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis

Steven P. Grover, Tomohiro Kawano, Jun Wan, Pansakorn Tanratana, Zsofia Polai, Young J. Shim, Omri Snir, Sigrid Brækkan, Sophia Dhrolia, Rohan R. Kasthuri, Pavan K. Bendapudi, Keith R. McCrae, Alisa S. Wolberg, John-Bjarne Hansen, Henriette Farkas, Nigel Mackman

Blood (2023) 141 (19): 2390–2401.

https://doi.org/10.1182/blood.2022018849

Published: 2023

Includes: Supplemental data

Journal Articles

Use of Plasmic Scores to Aid Diagnosis of aHUS: A Real-World Analysis of Hospitalized Patients from the Premier Healthcare Database

Christoph Gasteyger, Miguel G Uriol-Rivera, Ana I Ávila, Robert S Makar, Frank R Ernst, John N Booth III, Angels Comas, Ching Lum, Ioannis Tomazos, Yan Wang, Pavan K. Bendapudi

Blood (2022) 140 (Supplement 1): 2780–2781.

https://doi.org/10.1182/blood-2022-155843

Published: 2022

Journal Articles

Coagulation Factor XII Is Activated Via Noncanonical Binding to Platelet Integrin αIIbβ3

Sharjeel Chaudhry, Randall Burton, Matthew Serrata, Louis Feingold, Lindsay Tomczak, Lindsay Collier, Dylan Laprise, Keiichi Enjyoji, Virendar Kaushik, Dylan Bertovich, Alex Burgin, Pavan K. Bendapudi

Blood (2022) 140 (Supplement 1): 971–972.

https://doi.org/10.1182/blood-2022-170622

Published: 2022

Journal Articles

A Machine-Learning Derived Red Blood Cell Morphology Tool Enables Differential Diagnosis and Novel Single-Cell Analyses

Brody Foy, Jonathan Stefely, Pavan K. Bendapudi, Robert P. Hasserjian, Hanny Al-Samkari, Abner Louissaint, Jr., Megan J Fitzpatrick, Bailey Hutchison, Christopher Mow, Julia Collins, Hasmukh P. Patel, Chhaya Patel, Nikita Patel, Samantha Ho, Richard M Kaufman, Walter Dzik, John M. Higgins, Robert S Makar

Blood (2022) 140 (Supplement 1): 10704–10705.

https://doi.org/10.1182/blood-2022-170422

Published: 2022

Journal Articles

Rare Variant Genetic Association Study for Transplant-Associated Thrombotic Microangiopathy (TA-TMA) Via Whole Exome Sequencing

Zhihui Zhang, Qian Vicky Wu, Christopher I Amos, Yanhong Liu, Hong Wei, Chao Cheng, Spiridon Tsavachidis, Angela Bryce, Sarah E Sartain, Caridad A. Martinez, Vahid Afshar-Kharghan, Jing-fei Dong, Pavan Bhatraju, Paul J Martin, Stephanie J. Lee, Robert S. Makar, Pavan K. Bendapudi, Ang Li

Blood (2021) 138 (Supplement 1): 745.

https://doi.org/10.1182/blood-2021-149438

Published: 2021

Journal Articles

Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura

George Goshua, Pranay Sinha, Jeanne E. Hendrickson, Christopher Tormey, Pavan K. Bendapudi, Alfred Ian Lee

Blood (2021) 137 (7): 969–976.

https://doi.org/10.1182/blood.2020006052

Published: 2021

Includes: Supplemental data

Journal Articles

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection

Hanny Al-Samkari, Rebecca S. Karp Leaf, Walter H. Dzik, Jonathan C. T. Carlson, Annemarie E. Fogerty, Anem Waheed, Katayoon Goodarzi, Pavan K. Bendapudi, Larissa Bornikova, Shruti Gupta, David E. Leaf, David J. Kuter, Rachel P. Rosovsky

Blood (2020) 136 (4): 489–500.

https://doi.org/10.1182/blood.2020006520

Published: 2020

Includes: Supplemental data

Journal Articles

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

Pavan K. Bendapudi, MD, Karen Deceunynck, PhD, Secil Koseoglu, PhD, Roelof Hendrik Bekendam, MD, Shauna D Mason, Jon Kenniston, Robert C. Flaumenhaft, MD PhD

Blood (2016) 128 (22): 258.

https://doi.org/10.1182/blood.V128.22.258.258

Published: 2016

Journal Articles

Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation

Roelof H Bekendam, MD, Gopal Srila, MD, Pavan K Bendapudi, MD, James R Dilks, Lin Lin, PhD, Sheryl Bowley, PhD, Jack Stopa, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Kevin Croce, MD/ PhD, Robert Flaumenhaft, MD/ PhD

Blood (2014) 124 (21): 93.

https://doi.org/10.1182/blood.V124.21.93.93

Published: 2014

Journal Articles

Derivation and Prospective Validation of a Predictive Score for the Rapid Diagnosis of Thrombotic Thrombocytopenic Purpura: The Plasmic Score

Pavan K Bendapudi, MD, Ang Li, MD, Ayad Hamdan, MD, Ashley Michelle Fry, MD, Lynne Uhl, MD, Marisa Marques, MD, Richard Kaufman, MD, Christopher P. Stowell, MD PhD, Walter Sunny Dzik, MD, Robert S Makar, MD PhD

Blood (2014) 124 (21): 231.

https://doi.org/10.1182/blood.V124.21.231.231

Published: 2014

Journal Articles

ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity

Pavan K Bendapudi, MD, Roelof H Bekendam, MD, Lin Lin, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Robert Flaumenhaft, MD/ PhD

Blood (2014) 124 (21): 2880.

https://doi.org/10.1182/blood.V124.21.2880.2880

Published: 2014

NARROW

Thrombosis risk in single- and double-heterozygous carriers of factor V Leiden and prothrombin G20210A in FinnGen and the UK Biobank

Low-frequency inherited complement receptor variants are associated with purpura fulminans

Coagulation Factor XII ( F12 ) Haploinsufficiency Is Protective Against Venous Thromboembolism in 415,921 Individuals

Clinical Consequences of Rare Germline Variation in Genes Associated with Coagulation across 451,958 Individuals

Protein Z ( PROZ ) Loss of Function Is Associated with Increased Risk of Ischemic Stroke in 416,767 UK Biobank Participants

Meta-Analysis of National-Level Genotyping Datasets to Determine the Risk of Thrombosis in Double Heterozygous Carriers of Factor V Leiden and the Prothrombin G20210A Mutation across 876,417 Individuals

Determinants and Clinical Impact of Time to Plasma Exchange in Patients with Immune Thrombotic Thrombocytopenic Purpura

Association between Hereditary Angioedema and Venous Thromboembolism in a Large Population-Based Case-Control Study

Rare Germline Loss-of-Function Variants in HSP47 ( SERPINH1 ) Are Associated with an Intermediate Osteogenesis Imperfecta Phenotype Characterized By Atopic Inflammation and Increased Risk of Thrombosis

C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis

Use of Plasmic Scores to Aid Diagnosis of aHUS: A Real-World Analysis of Hospitalized Patients from the Premier Healthcare Database

Coagulation Factor XII Is Activated Via Noncanonical Binding to Platelet Integrin αIIbβ3

A Machine-Learning Derived Red Blood Cell Morphology Tool Enables Differential Diagnosis and Novel Single-Cell Analyses

Rare Variant Genetic Association Study for Transplant-Associated Thrombotic Microangiopathy (TA-TMA) Via Whole Exome Sequencing

Cost effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation

Derivation and Prospective Validation of a Predictive Score for the Rapid Diagnosis of Thrombotic Thrombocytopenic Purpura: The Plasmic Score

ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity

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American Society of Hematology

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ASH Publications

American Society of Hematology

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