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Peter P. Sayeski
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Journal Articles

Whole Exome Sequencing and Extended Thrombophilia Testing in Patients with Venous Thromboembolism

Free
Lauren Marsh Shevell, MD MPH, Eun-Ju Lee, MD, Rahul Dhodapkar, MBBS, Daniel Dykas, BS, MBA, Andreea Popa, MD PhD, Deqiong Ma, MD PhD, Noffar Bar, MD, Audrey Baluha, RN, Adrienne J. Burns, MMS, PA-C, Cassius Ilya Ochoa Chaar, MD, Anne Dupont, RN, Sean Gu, MD PhD, Stephanie Halene, MD, Randy Luciano, MD PhD, Rebecca Marien, RN, Natalia Neparidze, MD, Terri L Parker, MD, Xiaopan Yao, PhD, Rodney M. Camire, PhD, Eduard Ebberink, PhD, Pablo Garcia de Frutos, Kavitha Gnanasambandan, PhD, Peter P. Sayeski, PhD, James A. Huntington, PhD, Steven R. Lentz, MD PhD, Koen Mertens, PhD, Christopher Parish, PhD, Ray Rezaie, PhD, Jean M. Connors, BA, MD, Andrew Leavitt, MD, Allen Bale, MD, Alfred Ian Lee, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2506.
https://doi.org/10.1182/blood-2018-99-115529
Published: 2018
Journal Articles

Predictive Simulation Modeling in JAK2-Mutant MPNs Identified Ruxolitinib and Sorafenib As a Synergistic Drug Combination for Disease Modifying Therapy

Free
Peter P. Sayeski, PhD, Leylah M. Drusbosky, PhD, Neeraj Kumar Singh, B.Tech, Anusha Pampana, Shahabuddin Usmani, MS, Mohammed Sauban, BE, Abha Kushwaha, Anu Ramakrishnan, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5287.
https://doi.org/10.1182/blood.V130.Suppl_1.5287.5287
Published: 2017
Journal Articles

A Novel Method of Using Molecular Profiling in Myelodysplastic Syndromes to Predict Patient-Specific Potential Therapeutics

Free
Christopher R. Cogle, MD, Gaurav Trikha, MBBS, MD, Peter P. Sayeski, PhD, Shireen Vali, PhD, Ansu Kumar, Neeraj Kumar Singh, Prashant R Nair, Deepak Anil Lala, Kabya Basu, Taher Abbasi, MS, Maher Albitar, MD
Journal: Blood
Blood (2014) 124 (21): 5591.
https://doi.org/10.1182/blood.V124.21.5591.5591
Published: 2014
Journal Articles

A Novel Simulation Method for Mapping Dysregulated Pathways and Predicting Effective Therapeutics in the Myelodysplastic Syndromes

Free
Christopher R. Cogle, MD, Kaoru Tohyama, MD PhD, Shireen Vali, PhD, Ansu Kumar, Neeraj Kumar Singh, Krishna Kumar Tiwari, Anuj Tyagi, Taher Abbasi, MS, Peter P. Sayeski, PhD
Journal: Blood
Blood (2014) 124 (21): 5595.
https://doi.org/10.1182/blood.V124.21.5595.5595
Published: 2014
Journal Articles

Personalized Therapy Design for MPN Using Predictive Simulation Methodology with in Vitro, Ex Vivo, and in Vivo Validatio

Free
Peter P. Sayeski, PhD, Shireen Vali, PhD, Ansu Kumar, Sung Park, PhD, Neeraj Kumar Singh, Anuj Tyagi, Taher Abbasi, MS, Christopher R. Cogle, MD
Journal: Blood
Blood (2014) 124 (21): 3212.
https://doi.org/10.1182/blood.V124.21.3212.3212
Published: 2014
Journal Articles

Aberrant Functions of Mast Cells Are Involved in Pruritus Associated with Polycythemia Vera

Free
Xi Jin, Wanke Zhao, Annet Kirabo, Sung Park, Ph.D., Wanting Ho, Peter P. Sayeski, Ph.D., Zhizhuang Joe Zhao, PhD
Journal: Blood
Blood (2012) 120 (21): 1756.
https://doi.org/10.1182/blood.V120.21.1756.1756
Published: 2012
Journal Articles

The Jak2 Kinase Inhibitor, G6, Reduces the Mutant Burden and Reverses Marrow Fibrosis in a Mouse Model of Jak2-V617F Mediated PMF,

Free
Peter P. Sayeski, Ph.D., Annet Kirabo, Sung Park, Ph.D., Meghanath Gali, Mary Reinhard, DVM, DACLAM, Heather L Wamsley, Zhizhuang Joe Zhao, PhD, Kirpal S Bisht, Christopher R Cogle, M.D., Gyorgy M Keseru
Journal: Blood
Blood (2011) 118 (21): 3858.
https://doi.org/10.1182/blood.V118.21.3858.3858
Published: 2011
Journal Articles

Jak2 Plays a Critical and Non-Redundant Role In Hematopoiesis throughout Pre- and Post-Natal Life

Free
Sung Park, Ph.D., Kavitha Gnanasambandan, Peter P. Sayeski, Ph.D.
Journal: Blood
Blood (2010) 116 (21): 2238.
https://doi.org/10.1182/blood.V116.21.2238.2238
Published: 2010
Journal Articles

Transforming and Tumorogenic Activity of JAK2 by Fusion to BCR: Molecular Mechanisms of Action of a Novel BCR-JAK2 Tyrosin-Kinase.

Free
Álvaro Cuesta-Domínguez, Mara Ortega, Cristina Ormazabal, Matilde Santos-Roncero, Marta Galán-Díez, Juan Luis Steegmann, MD, PhD, Eva Arranz, María Ángeles Figuera, Jaqueline Sayyah, MS, Peter P. Sayeski, PhD, José Luis Vizmanos, Juan A. Bueren, Paula Rio, Elena Fernandez-Ruiz
Journal: Blood
Blood (2009) 114 (22): 4683.
https://doi.org/10.1182/blood.V114.22.4683.4683
Published: 2009
Journal Articles

Identification and Characterization of a Series of Novel Jak2 Small Molecule Inhibitor Compounds.

Free
Jacqueline Sayyah, MS, Robert W. Allen, M.D., Raul C. Braylan, M.D., Gyorgy M. Keseru, Ph.D., Peter P. Sayeski, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 539.
https://doi.org/10.1182/blood.V110.11.539.539
Published: 2007