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Deepak Anil Lala
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Journal Articles

Therapy Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Is Predictive of Individual Acute Myeloid Leukemia (AML) Patient Probability of Clinical Response (CR) and Overall Survival (OS): Mycare-023

Scott C Howard, Drew Watson, Michael Castro, Shweta Kapoor, Prashant Ramachandran Nair, Samiksha Avinash Prasad, Swaminathan Rajagopalan, Aftab Alam, Kunal Ghosh Roy, Diwyanshu Sahu, Deepak Anil Lala, Kabya Basu, Yashaswini S Ullal, Yugandhara Narvekar, Adity Ghosh, Mohammed Sauban, Poornachandra G, Ashish Kumar Agrawal, Anuj Tyagi, Rakhi Purushothaman Suseela, Karthik Sundara Raju, Anusha Pampana, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 689.
https://doi.org/10.1182/blood-2021-154023
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Predicted Novel Biomarkers for Hyper-CVAD (CVAD) Treatment Response and Combination of Rituximab and Cladribine (RC) in CVAD Resistant Cases of Mantle Cell Lymphoma (MCL)

Guido Marcucci, Ansu Kumar, Michael Castro, Swati Khandelwal, Subrat Mohapatra, Shweta Kapoor, Ashish Kumar Agrawal, Mohammed Sauban, Kabya Basu, Vijayashree P Shyamasundar, Deepak Anil Lala, Karthik Sundara Raju, Naga Ganesh Palaniyeppa, Yashaswini S Ullal, Vishwas Joseph, Liptimayee Behura, Diwyanshu Sahu, Annapoorna Prakash, Upasana Mitra, Ashokraja Balla, Mamatha Patil, Jharana Mohanty, Sanjana Patel, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 3550.
https://doi.org/10.1182/blood-2021-152423
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Immune Modulation As a Key Pathway for Predicting Azacitidine (AZA) Response in Myelodysplastic Syndromes (MDS)

Scott C Howard, Ansu Kumar, Michael Castro, Himanshu Grover, Subrat Mohapatra, Shweta Kapoor, Anuj Tyagi, Prashant Ramachandran Nair, Rakhi Purushothaman Suseela, Anusha Pampana, Deepak Anil Lala, Divya Singh, Vijayashree P Shyamasundar, Shruthi Kulkarni, Yugandhara Narvekar, Kritika Sahni, Rahul K Raman, Veena Balakrishnan, Mamatha Patil, Naga Ganesh Palaniyeppa, Ashokraja Balla, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 3690.
https://doi.org/10.1182/blood-2021-153539
Published: 2021
Journal Articles

Predicting Resistance to the Combination of ATO and ATRA in APL Patients with PML-Rara Fusions, Using a Computational Biology Modeling Approach: Mycare-021-01

Scott Howard, MD, Prashant Ramachandran Nair, B.Tech., Himanshu Grover, M.S., Anuj Tyagi, M.Sc., Pallavi Kumari, M.Sc., Samiksha Avinash Prasad, M.Sc., Upasana Mitra, M.Sc., Deepak Anil Lala, B.Tech., Humera Azam, M.Sc., Neha Gupta, M.Sc., Subrat Mohapatra, M.Sc., Poornachandra G, B.Tech., Nirjhar Mundkur, Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc.
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-140617
Published: 2020
Journal Articles

Comparative Analysis for Differential Drug Response between Early T-Cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) and T-Cell Acute Lymphoblastic Leukemia (T-ALL) Patients Using the Cellworks Omics Biology Model (CBM): Mycare-021-03

Scott Howard, MD, Ansu Kumar, M.Sc., Anusha Pampana, M.Sc., Yashaswini S Ullal, M.Tech., Anuj Tyagi, M.Sc., Deepak Anil Lala, B.Tech., Pallavi Kumari, M.Sc., Vishwas Joseph, M.Sc., Karthik Sundara Raju, M.Sc., Veena Balakrishnan, M.Sc., Nirjhar Mundkur, B.S., Michele Dundas Macpherson, B.A.Sc., Prashant Ramachandran Nair, B.Tech., Shweta Kapoor, M.Sc.
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-139997
Published: 2020
Journal Articles

Analysis of the Evolving MDS/AML Clones to Identify Resistance Mechanisms and Predict New Therapy Options at Relapse Using Computational Biology Modeling: Case-Studies from iCare1 Clinical Study

Shireen Vali, PhD, Taher Abbasi, MS, MBA, Neeraj Kumar Singh, B.Tech, Shahabuddin Usmani, M.Sc., Deepak Anil Lala, B.Tech, Poornachandra G, B.Tech, Saumya Radhakrishnan, B.Tech, Shivgonda C Birajdar, MCA, Ganesh Naga, B.Tech, Leylah M. Drusbosky, PhD, Christopher R. Cogle, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3086.
https://doi.org/10.1182/blood-2018-99-115821
Published: 2018
Journal Articles

Digital Drug Screening and Computational Modeling Identifies Treatment Opportunities Despite Lack of Directly Actionable Mutations in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS)

Leylah M. Drusbosky, PhD, Kimberly E. Hawkins, PhD BS, Madeleine Turcotte, MS, Hemant S. Murthy, MD, Helen L. Leather, Nosha Farhadfar, MD, Maxim Norkin, MD, John R. Wingard, MD, John W. Hiemenz, MD, Paul Castillo, MD, Randy A. Brown, MD, William Slayton, MD, Biljana N. Horn, MD, Sumanth Vasista, BE, Kabya Basu, MS, Shahabuddin Usmani, MS, Kunal Ghosh Roy, MS, Deepak Anil Lala, BT, Saumya Radhakrishnan, BT, Rajeev Kumar, BT, Swaminathan Rajagopalan, MT, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3910.
https://doi.org/10.1182/blood.V130.Suppl_1.3910.3910
Published: 2017
Journal Articles

A Novel Method of Using Molecular Profiling in Myelodysplastic Syndromes to Predict Patient-Specific Potential Therapeutics

Christopher R. Cogle, MD, Gaurav Trikha, MBBS, MD, Peter P. Sayeski, PhD, Shireen Vali, PhD, Ansu Kumar, Neeraj Kumar Singh, Prashant R Nair, Deepak Anil Lala, Kabya Basu, Taher Abbasi, MS, Maher Albitar, MD
Journal: Blood
Blood (2014) 124 (21): 5591.
https://doi.org/10.1182/blood.V124.21.5591.5591
Published: 2014