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Journal Articles

Therapy Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Is Predictive of Individual Acute Myeloid Leukemia (AML) Patient Probability of Clinical Response (CR) and Overall Survival (OS): Mycare-023

Scott C Howard, Drew Watson, Michael Castro, Shweta Kapoor, Prashant Ramachandran Nair, Samiksha Avinash Prasad, Swaminathan Rajagopalan, Aftab Alam, Kunal Ghosh Roy, Diwyanshu Sahu, Deepak Anil Lala, Kabya Basu, Yashaswini S Ullal, Yugandhara Narvekar, Adity Ghosh, Mohammed Sauban, Poornachandra G, Ashish Kumar Agrawal, Anuj Tyagi, Rakhi Purushothaman Suseela, Karthik Sundara Raju, Anusha Pampana, Sanjana Patel, Nirjhar Mundkur, James Christie, Michele Dundas Macpherson, Guido Marcucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 689.
https://doi.org/10.1182/blood-2021-154023
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Identifies Genomic and Molecular Markers for Decitabine (DAC) Plus Valproic-Acid (VPA) Treatment Response in Patients with Myelodysplastic Syndromes (MDS)

Michael Castro, Ansu Kumar, Himanshu Grover, Vivek Patil, Shweta Kapoor, Ashish Kumar Agrawal, Mohammed Sauban, Samiksha Avinash Prasad, Kabya Basu, Rakhi Purushothaman Suseela, Chandan Kumar, Prashant Ramachandran Nair, Pallavi Kumari, Anusha Pampana, Yashaswini S Ullal, Humera Azam, Nagendra Prasad, Anish Raju R Amara, Diwyanshu Sahu, Nithya T Raveendaran, Archana Palillam Veedu, Nirjhar Mundkur, Sanjana Patel, James Christie, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 2615.
https://doi.org/10.1182/blood-2021-153220
Published: 2021
Journal Articles

Biosimulation Using the Cellworks Computational Omics Biology Model (CBM) Predicted Novel Biomarkers for Hyper-CVAD (CVAD) Treatment Response and Combination of Rituximab and Cladribine (RC) in CVAD Resistant Cases of Mantle Cell Lymphoma (MCL)

Guido Marcucci, Ansu Kumar, Michael Castro, Swati Khandelwal, Subrat Mohapatra, Shweta Kapoor, Ashish Kumar Agrawal, Mohammed Sauban, Kabya Basu, Vijayashree P Shyamasundar, Deepak Anil Lala, Karthik Sundara Raju, Naga Ganesh Palaniyeppa, Yashaswini S Ullal, Vishwas Joseph, Liptimayee Behura, Diwyanshu Sahu, Annapoorna Prakash, Upasana Mitra, Ashokraja Balla, Mamatha Patil, Jharana Mohanty, Sanjana Patel, Michele Dundas Macpherson, Scott C Howard
Journal: Blood
Blood (2021) 138 (Supplement 1): 3550.
https://doi.org/10.1182/blood-2021-152423
Published: 2021
Journal Articles

Superior Therapy Response Predictions for Patients with Myelodysplastic Syndrome (MDS) Using Cellworks Singula™: Mycare-020-02

Anthony S. Stein, MD, Drew Watson, PhD, Prashant Ramachandran Nair, B.Tech., Kabya Basu, M.Sc., Yashaswini S Ullal, M.Tech., Adity Ghosh, M.Sc., Yugandhara Narvekar, M.Sc., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Annapoorna Prakash, M.Tech., Liptimayee Behura, B.E., Veena Balakrishnan, M.Sc., Kunal Ghosh Roy, M.Sc., Swaminathan Rajagopalan, M.Tech., Aftab Alam, M.Sc., Rajan Parashar, B.Tech., Nirjhar Mundkur, James Christie, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Guido Marcucci, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-142214
Published: 2020
Journal Articles

Assessment of Cellworks Omics Biosimulation Therapy Response Predictions for Patients with Acute Myeloid Leukemia (AML) Using Cellworks Singula™: Mycare-020-01

Guido Marcucci, MD, Drew Watson, PhD, Prashant Ramachandran Nair, B.Tech., Kabya Basu, M.Sc., Yashaswini S Ullal, M.Tech., Adity Ghosh, M.Sc., Yugandhara Narvekar, M.Sc., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Anish Raju R Amara, B.E., Anusha Pampana, M.Sc., Kunal Ghosh Roy, M.Sc., Swaminathan Rajagopalan, M.Tech., Aftab Alam, M.Sc., Rajan Parashar, B.Tech., Nirjhar Mundkur, James Christie, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Anthony S. Stein, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-142184
Published: 2020
Journal Articles

Monosomy 7 and Co-Occurrent Genomic Aberrations Determine Chemotherapy Response in Acute Myeloid Leukemia (AML) Patients Using the Cellworks Omics Biology Model (CBM): Mycare-021-04

Michael Castro, MD, Drew Watson, PhD, Ansu Kumar, M.Sc., Prashant Ramachandran Nair, B.Tech., Himanshu Grover, M.S., Diwyanshu Sahu, M.Sc., Subrat Mohapatra, M.Sc., Poornachandra G, B.Tech., Ashish Agarwal, B.V.Sc., Rakhi Purushothaman Suseela, B.Tech., Naga Ganesh, B.Tech., Mohammed Sauban, B.E., Chandan Kumar, M.Tech., Rahul K Raman, M.Sc., Divya Singh, M.S., Sayani Basu, M.Tech., Neelesh Lunkad, M.Tech., Nirjhar Mundkur, B.S., Michele Dundas Macpherson, B.A.Sc., Shweta Kapoor, M.Sc., Scott Howard, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9.
https://doi.org/10.1182/blood-2020-140087
Published: 2020
Journal Articles

Predicting Response to Dasatinib Using a Computational Model and Its Validation: A Beat AML Project Study

Jeffrey W. Tyner, PhD, Brian J. Druker, MD, Cristina E. Tognon, PhD, Stephen E Kurtz, PhD, Leylah M. Drusbosky, PhD, Diwyanshu Sahu, M.Sc., Robinson Vidva, B.Tech, Shweta Kapoor, M.Sc., Humera Azam, M.Sc., Rajeev Kumar, B.Tech, Padmagiri G Chickdipatti, B.E, Nithya T Raveendaran, M.Tech, Reshma P Gopi, M.Sc., Taher Abbasi, MS, MBA, Shireen Vali, PhD, Christopher R. Cogle, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1541.
https://doi.org/10.1182/blood-2018-99-115678
Published: 2018
Journal Articles

A Study to Predict Response to Azacitidine or Lenalidomide/Azacitidine Combination Therapy in MDS and AML Patients Using a Computational Biological Modeling (CBM) Approach

Ravi Vij, MDMBA, Mark A. Fiala, BS, Mathew A. Cherian, MBBS, Neeraj Kumar Singh, B.Tech, Diwyanshu Sahu, M.Sc., Ilu Kumari, M.Sc., Ankitha Narayan, B.E, Poornachandra G, B.Tech, Shireen Vali, PhD, Taher Abbasi, MS, MBA
Journal: Blood
Blood (2017) 130 (Supplement 1): 2978.
https://doi.org/10.1182/blood.V130.Suppl_1.2978.2978
Published: 2017
Journal Articles

Computational Biology Approach to Predict Hypomethylating Agent (HMA) Response Using Genomic and Clinical Characteristics in Myelodsyplastic Syndromes (MDS)

Leylah M. Drusbosky, PhD, Salah-Eddin Komrokji, Najla Al Ali, M.Sc, Neeraj Kumar Singh, B.Tech, Chandan Kumar, MT, Sumanth Vasista, BE, Diwyanshu Sahu, M.Sc., Ganesh Naga, BT, Patil Dattatraya, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, David A Sallman, MD, Rami S. Komrokji, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2954.
https://doi.org/10.1182/blood.V130.Suppl_1.2954.2954
Published: 2017