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Journal Articles

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Weiqing Jing, MD PhD, Juan Chen, PhD, Yuanhua Cai, MD, Yingyu Chen, PhD, Jocelyn A. Schroeder, Weiguo Cui, MD PhD, Qizhen Shi, MD PhD

Blood (2019) 134 (Supplement_1): 92.

https://doi.org/10.1182/blood-2019-123777

Published: 2019

Journal Articles

Fludarabine in Combination with Busulfan As Pretransplant Conditioning for Platelet Gene Therapy in Murine Hemophilia a with Inhibitors

Yingyu Chen, PhD, Jing Li, MD PhD, Jocelyn A. Schroeder, Weiqing Jing, MD PhD, Jianda Hu, PhD, Qizhen Shi, MD PhD

Blood (2019) 134 (Supplement_1): 1108.

https://doi.org/10.1182/blood-2019-127410

Published: 2019

Journal Articles

Animal Models Demonstrate a Critical Role of Factor VIII in Par4- and Platelet-Mediated Pathology

Michelle Castillo, BS, Quihui Yang, MD PhD, Dosia McKinney, Qizhen Shi, MD PhD, Rashmi Sood, PhD

Blood (2019) 134 (Supplement_1): 1057.

https://doi.org/10.1182/blood-2019-123290

Published: 2019

Journal Articles

Platelet-Targeted Gene Therapy of Hemophilia a Using Hematopoietic Stem Cells Derived from Genome-Edited Induced Pluripotent Stem Cells

Dawei Wang, Guowei Zhang, Junjie Gu, Xiaohu Shao, Xiaohong Pan, Shuxian Yao, Ying Jin, Qizhen Shi, MD PhD, Zhu Chen, PhD, Sai-Juan Chen, PhD

Blood (2017) 130 (Supplement 1): 2063.

https://doi.org/10.1182/blood.V130.Suppl_1.2063.2063

Published: 2017

Journal Articles

Platelet-Targeted Gene Transfer Induces Immune Tolerance in a Primed Model

Jing Li, MD PhD, Juan Chen, PhD, Jocelyn Schroeder, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2017) 130 (Supplement 1): 4612.

https://doi.org/10.1182/blood.V130.Suppl_1.4612.4612

Published: 2017

Journal Articles

E35, a Novel Analog of Emodin, Selectively Eliminates Acute Leukemia Stem and Progenitor Cells

Yingyu Chen, PhD, Jing Zheng, PhD, Zhenxing Lin, Jing Li, PhD, Qizhen Shi, MD PhD, Jianda Hu, MD PhD

Blood (2016) 128 (22): 5213.

https://doi.org/10.1182/blood.V128.22.5213.5213

Published: 2016

Journal Articles

The Impact of VWF on FVIII Immune Responses in Hemophilia a Mice with Pre-Existing Anti-FVIII Immunity

Juan Chen, PhD, Jocelyn A. Schroeder, Xiaofeng Luo, MD PhD, Robert R. Montgomery, MD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 84.

https://doi.org/10.1182/blood.V128.22.84.84

Published: 2016

Journal Articles

Platelet-Targeted Gene Transfer Prevents Graft Rejection and Induces Immune Tolerance Even in a Primed Model

Xiaofeng Luo, MD, PhD, Jing Li, MD PhD, Juan Chen, PhD, Jocelyn A. Schroeder, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 2315.

https://doi.org/10.1182/blood.V128.22.2315.2315

Published: 2016

Journal Articles

Platelet-Derived Codon-Optimized Hyperfunctional FIX Gene Therapy of Hemophilia B Mice

Jocelyn A. Schroeder, Mary A. Jozwiak, Paul E. Monahan, MD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 3751.

https://doi.org/10.1182/blood.V128.22.3751.3751

Published: 2016

Journal Articles

The Impact of GPIba on the Efficacy of Platelet-Targeted FVIII Gene Therapy in Hemophilia a with Pre-Existing Anti-FVIII Immunity

Juan Chen, PhD, Jocelyn Schroeder, Xiaofeng Luo, MD, Robert R Montgomery, MD, Qizhen Shi, MD PhD

Blood (2015) 126 (23): 1067.

https://doi.org/10.1182/blood.V126.23.1067.1067

Published: 2015

Journal Articles

Immune Tolerance Developed in Platelet-Targeted FVIII Gene Therapy in Hemophilia Mice Is CD4 + T Cell-Mediated

Yingyu Chen, PhD, Xiaofeng Luo, MD, Juan Chen, PhD, Jocelyn Schroeder, Christina K Baumgartner, PhD, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2015) 126 (23): 1071.

https://doi.org/10.1182/blood.V126.23.1071.1071

Published: 2015

Journal Articles

Platelet-Targeted Gene Transfer Induces Immune Tolerance through Two Distinct Pathways

Xiaofeng Luo, MD, Juan Chen, PhD, Jocelyn Schroeder, Christina K Baumgartner, PhD, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2015) 126 (23): 4423.

https://doi.org/10.1182/blood.V126.23.4423.4423

Published: 2015

Journal Articles

Platelet-Targeted Gene Transfer Induces Antigen-Specific Immune Tolerance

Luo Xiaofeng, Jocelyn A. Schroeder, Christina Baumgartner, PhD, Juan Chen, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2014) 124 (21): 2154.

https://doi.org/10.1182/blood.V124.21.2154.2154

Published: 2014

Journal Articles

The Immunogenicity of Platelet-Derived FVIII in Hemophilia a Mice with or without Pre-Existing Anti-FVIII Immunity

Yingyu Chen, PhD, Jocelyn Schroeder, Juan Chen, Xiaofeng Luo, MD, Christina Baumgartner, PhD, Robert R Montgomery, MD, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2014) 124 (21): 2809.

https://doi.org/10.1182/blood.V124.21.2809.2809

Published: 2014

Journal Articles

Lentivirus-Mediated Platelet Gene Therapy Corrects Bleeding Diathesis and Induces Immune Tolerance in Murine Hemophilia B Mice

Yingyu Chen, PhD, Jocelyn A. Schroeder, Erin L. Kuether, Guowei Zhang, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD

Blood (2012) 120 (21): 1101.

https://doi.org/10.1182/blood.V120.21.1101.1101

Published: 2012

Journal Articles

Bleeding Phenotype of Murine Bernard Soulier Syndrome Is Potentially Corrected by Non-Myeloablative Hematopoietic Stem Cell Transplantation

Sachiko Kanaji, MD, PhD, Scot A. Fahs, Jerry Ware, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD

Blood (2012) 120 (21): 3340.

https://doi.org/10.1182/blood.V120.21.3340.3340

Published: 2012

Journal Articles

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Qizhen Shi, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Robert R. Montgomery, MD

Blood (2011) 118 (21): 20.

https://doi.org/10.1182/blood.V118.21.20.20

Published: 2011

Journal Articles

Targeting FVIII Expression to Platelets Induces Immune Tolerance in Hemophilia A Mice with or without Pre-Existing Anti-FVIII Immunity,

Yingyu Chen, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Robert R. Montgomery, MD, David W. Scott, PhD, Qizhen Shi, MD, PhD

Blood (2011) 118 (21): 4170.

https://doi.org/10.1182/blood.V118.21.4170.4170

Published: 2011

Journal Articles

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

Lily M. Du, MD, Helen W.G. Franck, BS, Elizabeth P. Merricks, PhD, Paquita Nurden, MD, Eric S. Jensen, DVM, Sandra L. Haberichter, PhD, Troy B. Hawkins, PhD, Paula M. Jacobi, BS, Juan Fang, MD, Timothy C. Nichols, MD, Sevasti B. Koukouritaki, PhD, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD, Kenneth Cornetta, MD, Alan T. Nurden, PhD, David A. Wilcox, PhD

Blood (2010) 116 (21): 2198.

https://doi.org/10.1182/blood.V116.21.2198.2198

Published: 2010

Journal Articles

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Scot A. Fahs, David A. Wilcox, PhD, Robert R. Montgomery, MD

Blood (2010) 116 (21): 2201.

https://doi.org/10.1182/blood.V116.21.2201.2201

Published: 2010

NARROW

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Fludarabine in Combination with Busulfan As Pretransplant Conditioning for Platelet Gene Therapy in Murine Hemophilia a with Inhibitors

Animal Models Demonstrate a Critical Role of Factor VIII in Par4- and Platelet-Mediated Pathology

Platelet-Targeted Gene Therapy of Hemophilia a Using Hematopoietic Stem Cells Derived from Genome-Edited Induced Pluripotent Stem Cells

Platelet-Targeted Gene Transfer Induces Immune Tolerance in a Primed Model

E35, a Novel Analog of Emodin, Selectively Eliminates Acute Leukemia Stem and Progenitor Cells

The Impact of VWF on FVIII Immune Responses in Hemophilia a Mice with Pre-Existing Anti-FVIII Immunity

Platelet-Targeted Gene Transfer Prevents Graft Rejection and Induces Immune Tolerance Even in a Primed Model

Platelet-Derived Codon-Optimized Hyperfunctional FIX Gene Therapy of Hemophilia B Mice

The Impact of GPIba on the Efficacy of Platelet-Targeted FVIII Gene Therapy in Hemophilia a with Pre-Existing Anti-FVIII Immunity

Immune Tolerance Developed in Platelet-Targeted FVIII Gene Therapy in Hemophilia Mice Is CD4 + T Cell-Mediated

Platelet-Targeted Gene Transfer Induces Immune Tolerance through Two Distinct Pathways

Platelet-Targeted Gene Transfer Induces Antigen-Specific Immune Tolerance

The Immunogenicity of Platelet-Derived FVIII in Hemophilia a Mice with or without Pre-Existing Anti-FVIII Immunity

Lentivirus-Mediated Platelet Gene Therapy Corrects Bleeding Diathesis and Induces Immune Tolerance in Murine Hemophilia B Mice

Bleeding Phenotype of Murine Bernard Soulier Syndrome Is Potentially Corrected by Non-Myeloablative Hematopoietic Stem Cell Transplantation

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Targeting FVIII Expression to Platelets Induces Immune Tolerance in Hemophilia A Mice with or without Pre-Existing Anti-FVIII Immunity,

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

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American Society of Hematology

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American Society of Hematology

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