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Robert A Hromas
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Journal Articles

DT2216, a Synthetic Proteolytic Selectively Targeting Bcl-X L for Ubiquitination and Degradation in Tumor Cells but Not in Platelets, Is a Safer and More Potent Antitumor Agent Than Navitoclax

Sajid Khan, PhD, Xuan Zhang, BMBS, Dongwen Lv, PhD, Yonghan He, MD, Peiyi Zhang, MS, Xingui Liu, PhD, Dinesh Thummuri, PhD, Qi Zhang, PhD, Marina Y. Konopleva, MD PhD, Robert A. Hromas, MD, Guangrong Zheng, Daohong Zhou, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2698.
https://doi.org/10.1182/blood-2018-99-114762
Published: 2018
Journal Articles

Identification of a Small Molecule Inhibitor of RAD52 to Induce Synthetic Lethality in BRCA-Deficient Leukemias

Katherine Sullivan, Kimberly Cramer-Morales, Daniel L McElroy, David Ostrov, Kimberly Haas, Margaret Nieborowska-Skorska, Wayne Childers, Alexander Mazin, Robert A Hromas, Richard Pomerantz, Tomasz Skorski
Journal: Blood
Blood (2015) 126 (23): 4434.
https://doi.org/10.1182/blood.V126.23.4434.4434
Published: 2015
Journal Articles

Oct-4 Is Crucial for Stress-Induced Murine Embryonic Stem Cell Survival/Anti-Apoptosis Mediated by STAT3/Survivin.

Ying Guo, MD, MS, Charlie Mantel, B.S., Robert A. Hromas, M.D., Hal E. Broxmeyer, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 277.
https://doi.org/10.1182/blood.V108.11.277.277
Published: 2006
Journal Articles

oct-4 Is Essential for Aneuploidy/Polyploidy-Tolerance in Embryonic Stem (ES) Cells and the Fate of Tetraploid ES Cells during Early Differentiation.

Charlie R. Mantel, Ying Guo, Myung-Kwan Han, Sara Roharbaugh, Barbara Graham-Evans, Mervin C. Yoder, Robert A. Hromas, Hal E. Broxmeyer
Journal: Blood
Blood (2005) 106 (11): 311.
https://doi.org/10.1182/blood.V106.11.311.311
Published: 2005
Journal Articles

Oct-4 Is Crucial for Murine Embryonic Stem Cell Secretion of Cytokines/Growth Modulators That Enhance Cell Survival/Anti-Apoptosis of Murine ES Cells and Bone Marrow Hematopoietic Progenitor Cells.

Ying Guo, MD, Barbara Graham-Evans, PhD, Charlie R. Mantal, Robert A. Hromas, M.D, Hal E. Broxmeyer, PhD
Journal: Blood
Blood (2005) 106 (11): 1359.
https://doi.org/10.1182/blood.V106.11.1359.1359
Published: 2005
Journal Articles

AML1-FOG2 fusion protein in myelodysplasia

Brief Report
Edward M. Chan, Elisha M. Comer, Frank C. Brown, Kathleen E. Richkind, Melissa L. Holmes, Beng H. Chong, Roger Shiffman, Dong-Er Zhang, Marilyn L. Slovak, Cheryl L. Willman, Constance T. Noguchi, Yanjun Li, Devan J. Heiber, Lori Kwan, Rebecca J. Chan, Gail H. Vance, Heather C. Ramsey, Robert A. Hromas
Journal: Blood
Blood (2005) 105 (11): 4523–4526.
https://doi.org/10.1182/blood-2004-07-2762
Published: 2005
Journal Articles

Endothelial induction of the T-cell chemokine CCL21 in T-cell autoimmune diseases

Clinical Trials & Observations
Kent W. Christopherson, II, Antoinette F. Hood, Jeffrey B. Travers, Heather Ramsey, Robert A. Hromas
Journal: Blood
Blood (2003) 101 (3): 801–806.
https://doi.org/10.1182/blood-2002-05-1586
Published: 2003
Journal Articles

Transgenic overexpression of the CC chemokine CCL21 disrupts T-cell migration

Kent W. Christopherson, II, James J. Campbell, Robert A. Hromas
Journal: Blood
Blood (2001) 98 (13): 3562–3568.
https://doi.org/10.1182/blood.V98.13.3562
Published: 2001