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Journal Articles

Innate capability of clot contraction

Robert A. S. Ariëns

Blood (2024) 143 (6): 481–482.

https://doi.org/10.1182/blood.2023023200

Published: 2024

Journal Articles

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Alexandre Slater, Ying Di, Joanne C. Clark, Natalie J. Jooss, Eleyna M. Martin, Fawaz Alenazy, Mark R. Thomas, Robert A. S. Ariëns, Andrew B. Herr, Natalie S. Poulter, Jonas Emsley, Steve P. Watson

Blood (2021) 137 (24): 3443–3453.

https://doi.org/10.1182/blood.2020009440

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

Katherine J. Kearney, Nikoletta Pechlivani, Rhodri King, Christian Tiede, Fladia Phoenix, Ramsah Cheah, Fraser L. Macrae, Katie J. Simmons, Iain W. Manfield, Kerrie A. Smith, Benjamin E. J. Spurgeon, Khalid M. Naseem, Robert A. S. Ariens, Michael J. McPherson, Darren C. Tomlinson, Ramzi A. Ajjan

Blood (2019) 133 (11): 1233–1244.

https://doi.org/10.1182/blood-2018-06-856195

Published: 2019

Includes: Supplemental data

Journal Articles

Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII

Kelly Njine Mouapi, Jacob D. Bell, Kerrie A. Smith, Robert A. S. Ariëns, Helen Philippou, Muriel C. Maurer

Blood (2016) 127 (18): 2241–2248.

https://doi.org/10.1182/blood-2015-09-672303

Published: 2016

Includes: Supplemental data

Journal Articles

Thrombin and fibrinogen γ′ impact clot structure by marked effects on intrafibrillar structure and protofibril packing

Marco M. Domingues, Fraser L. Macrae, Cédric Duval, Helen R. McPherson, Katherine I. Bridge, Ramzi A. Ajjan, Victoria C. Ridger, Simon D. Connell, Helen Philippou, Robert A. S. Ariëns

Blood (2016) 127 (4): 487–495.

https://doi.org/10.1182/blood-2015-06-652214

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

Contribution of Red Blood Cells and Clot Structure to Thrombosis

Robert A S Ariens, PhD

Blood (2015) 126 (23): SCI-15.

https://doi.org/10.1182/blood.V126.23.SCI-15.SCI-15

Published: 2015

Journal Articles

Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

James R. Byrnes, Cédric Duval, Yiming Wang, Caroline E. Hansen, Byungwook Ahn, Micah J. Mooberry, Martha A. Clark, Jill M. Johnsen, Susan T. Lord, Wilbur A. Lam, Joost C. M. Meijers, Heyu Ni, Robert A. S. Ariëns, Alisa S. Wolberg

Blood (2015) 126 (16): 1940–1948.

https://doi.org/10.1182/blood-2015-06-652263

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Fibrinogen γ′ increases the sensitivity to activated protein C in normal and factor V Leiden plasma

Farida Omarova, Shirley Uitte de Willige, Paolo Simioni, Robert A. S. Ariëns, Rogier M. Bertina, Jan Rosing, Elisabetta Castoldi

Blood (2014) 124 (9): 1531–1538.

https://doi.org/10.1182/blood-2014-02-554055

Published: 2014

Journal Articles

A new red cell shape helps the clot

Robert A. S. Ariëns

Blood (2014) 123 (10): 1442–1443.

https://doi.org/10.1182/blood-2014-01-545459

Published: 2014

Journal Articles

Evidence that fibrinogen γ′ regulates plasma clot structure and lysis and relationship to cardiovascular risk factors in black Africans

Marlien Pieters, Retha C. Kotze, Johann C. Jerling, Annamarie Kruger, Robert A. S. Ariëns

Blood (2013) 121 (16): 3254–3260.

https://doi.org/10.1182/blood-2012-12-471482

Published: 2013

Includes: Supplemental data

Journal Articles

The activation peptide cleft exposed by thrombin cleavage of FXIII-A 2 contains a recognition site for the fibrinogen α chain

Kerrie A. Smith, Richard J. Pease, Craig A. Avery, Jane M. Brown, Penelope J. Adamson, Esther J. Cooke, Søs Neergaard-Petersen, Paul A. Cordell, Robert A. S. Ariëns, Colin W. G. Fishwick, Helen Philippou, Peter J. Grant

Blood (2013) 121 (11): 2117–2126.

https://doi.org/10.1182/blood-2012-07-446393

Published: 2013

Includes: Supplemental data

Journal Articles

Counting 1 fibrin molecule at a time

Robert A. S. Ariëns

Blood (2013) 121 (8): 1251–1252.

https://doi.org/10.1182/blood-2013-01-474635

Published: 2013

Journal Articles

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

Joke Konings, José W. P. Govers-Riemslag, Helen Philippou, Nicola J. Mutch, Julian I. Borissoff, Peter Allan, Sumitra Mohan, Guido Tans, Hugo ten Cate, Robert A. S. Ariëns

Blood (2011) 118 (14): 3942–3951.

https://doi.org/10.1182/blood-2011-03-339572

Published: 2011

Includes: Supplemental data

Journal Articles

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction

Shirley Uitte de Willige, Megan Miedzak, Angela M. Carter, Ton Lisman, Frits R. Rosendaal, Peter J. Grant, Helen Philippou, Robert A. S. Ariëns

Blood (2011) 117 (24): 6694–6701.

https://doi.org/10.1182/blood-2010-11-320325

Published: 2011

Journal Articles

Elevated fibrinogen causes thrombosis

Robert A. S. Ariëns

Blood (2011) 117 (18): 4687–4688.

https://doi.org/10.1182/blood-2011-03-340422

Published: 2011

Journal Articles

Interactions between factor XIII and the αC region of fibrinogen

Kerrie A. Smith, Penelope J. Adamson, Richard J. Pease, Jane M. Brown, Anthony J. Balmforth, Paul A. Cordell, Robert A. S. Ariëns, Helen Philippou, Peter J. Grant

Blood (2011) 117 (12): 3460–3468.

https://doi.org/10.1182/blood-2010-10-313601

Published: 2011

Includes: Supplemental data

Journal Articles

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

Nicola J. Mutch, Ruchira Engel, Shirley Uitte de Willige, Helen Philippou, Robert A. S. Ariëns

Blood (2010) 115 (19): 3980–3988.

https://doi.org/10.1182/blood-2009-11-254029

Published: 2010

Journal Articles

The pleiotropic role of the fibrinogen γ′ chain in hemostasis

Shirley Uitte de Willige, Kristina F. Standeven, Helen Philippou, Robert A. S. Ariëns

Blood (2009) 114 (19): 3994–4001.

https://doi.org/10.1182/blood-2009-05-217968

Published: 2009

Journal Articles

Denser matters

Robert A. S. Ariëns

Blood (2009) 114 (19): 3978–3979.

https://doi.org/10.1182/blood-2009-09-239921

Published: 2009

Journal Articles

Common variation in the C-terminal region of the fibrinogen β-chain: effects on fibrin structure, fibrinolysis and clot rigidity

Ramzi Ajjan, Bernard C. B. Lim, Kristina F. Standeven, Robert Harrand, Sarah Dolling, Fladia Phoenix, Richard Greaves, Radwa H. Abou-Saleh, Simon Connell, D. Alastair M. Smith, John W. Weisel, Peter J. Grant, Robert A. S. Ariëns

Blood (2008) 111 (2): 643–650.

https://doi.org/10.1182/blood-2007-05-091231

Published: 2008

NARROW

Innate capability of clot contraction

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII

Thrombin and fibrinogen γ′ impact clot structure by marked effects on intrafibrillar structure and protofibril packing

Contribution of Red Blood Cells and Clot Structure to Thrombosis

Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

Fibrinogen γ′ increases the sensitivity to activated protein C in normal and factor V Leiden plasma

A new red cell shape helps the clot

Evidence that fibrinogen γ′ regulates plasma clot structure and lysis and relationship to cardiovascular risk factors in black Africans

The activation peptide cleft exposed by thrombin cleavage of FXIII-A 2 contains a recognition site for the fibrinogen α chain

Counting 1 fibrin molecule at a time

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction

Elevated fibrinogen causes thrombosis

Interactions between factor XIII and the αC region of fibrinogen

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

The pleiotropic role of the fibrinogen γ′ chain in hemostasis

Denser matters

Common variation in the C-terminal region of the fibrinogen β-chain: effects on fibrin structure, fibrinolysis and clot rigidity

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American Society of Hematology

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ASH Publications

American Society of Hematology

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