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Journal Articles

Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity

Ramzi A. Ajjan, Toby Gamlen, Kristina F. Standeven, Salihah Mughal, Katharina Hess, Kerrie A. Smith, Emma J. Dunn, M. Maqsud Anwar, Naila Rabbani, Paul J. Thornalley, Helen Philippou, Peter J. Grant

Blood (2013) 122 (1): 134–142.

https://doi.org/10.1182/blood-2013-04-494641

Published: 2013

Journal Articles

The activation peptide cleft exposed by thrombin cleavage of FXIII-A 2 contains a recognition site for the fibrinogen α chain

Kerrie A. Smith, Richard J. Pease, Craig A. Avery, Jane M. Brown, Penelope J. Adamson, Esther J. Cooke, Søs Neergaard-Petersen, Paul A. Cordell, Robert A. S. Ariëns, Colin W. G. Fishwick, Helen Philippou, Peter J. Grant

Blood (2013) 121 (11): 2117–2126.

https://doi.org/10.1182/blood-2012-07-446393

Published: 2013

Includes: Supplemental data

Journal Articles

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

Jie Huang, Maria Sabater-Lleal, Folkert W. Asselbergs, David Tregouet, So-Youn Shin, Jingzhong Ding, Jens Baumert, Tiphaine Oudot-Mellakh, Lasse Folkersen, Andrew D. Johnson, Nicholas L. Smith, Scott M. Williams, Mohammad A. Ikram, Marcus E. Kleber, Diane M. Becker, Vinh Truong, Josyf C. Mychaleckyj, Weihong Tang, Qiong Yang, Bengt Sennblad, Jason H. Moore, Frances M. K. Williams, Abbas Dehghan, Günther Silbernagel, Elisabeth M. C. Schrijvers, Shelly Smith, Mahir Karakas, Geoffrey H. Tofler, Angela Silveira, Gerjan J. Navis, Kurt Lohman, Ming-Huei Chen, Annette Peters, Anuj Goel, Jemma C. Hopewell, John C. Chambers, Danish Saleheen, Per Lundmark, Bruce M. Psaty, Rona J. Strawbridge, Bernhard O. Boehm, Angela M. Carter, Christa Meisinger, John F. Peden, Joshua C. Bis, Barbara McKnight, John Öhrvik, Kent Taylor, Maria Grazia Franzosi, Udo Seedorf, Rory Collins, Anders Franco-Cereceda, Ann-Christine Syvänen, Alison H. Goodall, Lisa R. Yanek, Mary Cushman, Martina Müller-Nurasyid, Aaron R. Folsom, Saonli Basu, Nena Matijevic, Wiek H. van Gilst, Jaspal S. Kooner, Albert Hofman, John Danesh, Robert Clarke, James B. Meigs, DIAGRAM Consortium, Sekar Kathiresan, Muredach P. Reilly, CARDIoGRAM Consortium, Norman Klopp, Tamara B. Harris, Bernhard R. Winkelmann, Peter J. Grant, Hans L. Hillege, Hugh Watkins, C4D Consortium, Timothy D. Spector, Lewis C. Becker, Russell P. Tracy, Winfried März, Andre G. Uitterlinden, Per Eriksson, Francois Cambien, CARDIOGENICS Consortium, Pierre-Emmanuel Morange, Wolfgang Koenig, Nicole Soranzo, Pim van der Harst, Yongmei Liu, Christopher J. O'Donnell, Anders Hamsten

Blood (2012) 120 (24): 4873–4881.

https://doi.org/10.1182/blood-2012-06-436188

Published: 2012

Includes: Supplemental data

Journal Articles

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction

Shirley Uitte de Willige, Megan Miedzak, Angela M. Carter, Ton Lisman, Frits R. Rosendaal, Peter J. Grant, Helen Philippou, Robert A. S. Ariëns

Blood (2011) 117 (24): 6694–6701.

https://doi.org/10.1182/blood-2010-11-320325

Published: 2011

Journal Articles

Interactions between factor XIII and the αC region of fibrinogen

Kerrie A. Smith, Penelope J. Adamson, Richard J. Pease, Jane M. Brown, Anthony J. Balmforth, Paul A. Cordell, Robert A. S. Ariëns, Helen Philippou, Peter J. Grant

Blood (2011) 117 (12): 3460–3468.

https://doi.org/10.1182/blood-2010-10-313601

Published: 2011

Includes: Supplemental data

Journal Articles

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion

Paul A. Cordell, Benjamin T. Kile, Kristina F. Standeven, Emma C. Josefsson, Richard J. Pease, Peter J. Grant

Blood (2010) 115 (13): 2674–2681.

https://doi.org/10.1182/blood-2009-08-231316

Published: 2010

Includes: Supplemental data

Journal Articles

Common variation in the C-terminal region of the fibrinogen β-chain: effects on fibrin structure, fibrinolysis and clot rigidity

Ramzi Ajjan, Bernard C. B. Lim, Kristina F. Standeven, Robert Harrand, Sarah Dolling, Fladia Phoenix, Richard Greaves, Radwa H. Abou-Saleh, Simon Connell, D. Alastair M. Smith, John W. Weisel, Peter J. Grant, Robert A. S. Ariëns

Blood (2008) 111 (2): 643–650.

https://doi.org/10.1182/blood-2007-05-091231

Published: 2008

Journal Articles

Functional analysis of fibrin γ-chain cross-linking by activated factor XIII: determination of a cross-linking pattern that maximizes clot stiffness

Kristina F. Standeven, Angela M. Carter, Peter J. Grant, John W. Weisel, Irina Chernysh, Leona Masova, Susan T. Lord, Robert A. S. Ariëns

Blood (2007) 110 (3): 902–907.

https://doi.org/10.1182/blood-2007-01-066837

Published: 2007

Journal Articles

Genetics of fibrin clot structure: a twin study

Emma J. Dunn, Robert A. Ariëns, Marlies de Lange, Harold Snieder, John H. Turney, Timothy D. Spector, Peter J. Grant

Blood (2004) 103 (5): 1735–1740.

https://doi.org/10.1182/blood-2003-07-2247

Published: 2004

Journal Articles

Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms

Robert A. S. Ariëns, Thung-Shenq Lai, John W. Weisel, Charles S. Greenberg, Peter J. Grant

Blood (2002) 100 (3): 743–754.

https://doi.org/10.1182/blood.V100.3.743

Published: 2002

Journal Articles

The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure

Robert A. S. Ariëns, Helen Philippou, Chandrasekaran Nagaswami, John W. Weisel, David A. Lane, Peter J. Grant

Blood (2000) 96 (3): 988–995.

https://doi.org/10.1182/blood.V96.3.988

Published: 2000

Journal Articles

α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism

Angela M. Carter, Andrew J. Catto, Hans P. Kohler, Robert A. S. Ariëns, Max H. Stickland, Peter J. Grant

Blood (2000) 96 (3): 1177–1179.

https://doi.org/10.1182/blood.V96.3.1177

Published: 2000

Journal Articles

Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease

David A. Lane, Peter J. Grant

Blood (2000) 95 (5): 1517–1532.

https://doi.org/10.1182/blood.V95.5.1517.005k48_1517_1532

Published: 2000

Journal Articles

Association of a Common Polymorphism in the Factor XIII Gene With Venous Thrombosis

Andrew J. Catto, Hans P. Kohler, Julie Coore, Michael W. Mansfield, Max H. Stickland, Peter J. Grant

Blood (1999) 93 (3): 906–908.

https://doi.org/10.1182/blood.V93.3.906

Published: 1999

NARROW

Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity

The activation peptide cleft exposed by thrombin cleavage of FXIII-A 2 contains a recognition site for the fibrinogen α chain

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction

Interactions between factor XIII and the αC region of fibrinogen

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion

Common variation in the C-terminal region of the fibrinogen β-chain: effects on fibrin structure, fibrinolysis and clot rigidity

Functional analysis of fibrin γ-chain cross-linking by activated factor XIII: determination of a cross-linking pattern that maximizes clot stiffness

Genetics of fibrin clot structure: a twin study

Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms

The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure

α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism

Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease

Association of a Common Polymorphism in the Factor XIII Gene With Venous Thrombosis

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American Society of Hematology

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American Society of Hematology

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