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Journal Articles

Inhibition of Bcl-2 Signaling by Small Molecule BH3 Inhhibitor GX15-070 as a Novel Therapeutic Strategy in AML.

Julie C. Watt, Marina Konopleva, M.D., Ph.D., Rooha Contractor, Ismael Samudio, Ph.D., David Harris, Zeev Estrov, M.D., Jean Viallet, M.D., Michael Andreeff, M.D., Ph.D.

Blood (2006) 108 (11): 2584.

https://doi.org/10.1182/blood.V108.11.2584.2584

Published: 2006

Journal Articles

Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

Yoko Tabe, Marina Konopleva, Rooha Contractor, Mark Munsell, Wendy D. Schober, Linhua Jin, Yuko Tsutsumi-Ishii, Isao Nagaoka, Jun Igari, Michael Andreeff

Blood (2006) 107 (4): 1546–1554.

https://doi.org/10.1182/blood-2004-10-4126

Published: 2006

Journal Articles

Mechanisms of Apoptosis Induction by BH3 Inhibitor ABT-737 in AML.

Michael Andreeff, MD, PhD, Rooha Contractor, Peter P. Ruvolo, PhD, Xingming Deng, MD, PhD, Ismael Samudio, PhD, Yue-Xi Shi, Teresa McQueen, BS, Rui-Yu Wang, MD, PhD, Wendy Schober, Xiaoyang Ling, PhD, Frank C. Marini, PhD, David Harris, Zeev Estrov, MD, James McCubrey, PhD, W. Stratford May, MD, PhD, Marina Konopleva, MD, PhD

Blood (2005) 106 (11): 244.

https://doi.org/10.1182/blood.V106.11.244.244

Published: 2005

Journal Articles

Mechanisms and Activity of PPARγ-Active Triterpenoids CDDO and CDDO-Me in Leukemias.

Marina Konopleva, MD, PhD, Ismael Samudio, PhD, Twee Tsao, Steven M. Kornblau, MD, Yue-Xi Shi, Teresa McQueen, BS, Rooha Contractor, Michael B. Sporn, MD, Colin J. Meyer, MD, Warren Huff, Stephen H. Safe, PhD, Hagop Kantarjian, MD, Michael Andreeff, MD, PhD

Blood (2005) 106 (11): 2460.

https://doi.org/10.1182/blood.V106.11.2460.2460

Published: 2005

Journal Articles

Inhibition of Bcl-2 Signaling by Small Molecule BH3 Inhibitor GX15-070 as a Novel Therapeutic Strategy in AML.

Rooha Contractor, Marina Konopleva, MD, PhD, Ismael Samudio, PhD, Hagop Kantarjian, MD, Michael Andreeff, MD, PhD

Blood (2005) 106 (11): 3372.

https://doi.org/10.1182/blood.V106.11.3372.3372

Published: 2005

Journal Articles

Relationship between m-TOR-Mediated Upregulation of Glycolysis, Chemoresistance, and Prognosis in Patients with ALL.

Daniela Buglio, PhD, Marina Konopleva, MD, PhD, Teresa McQueen, BS, Ismael Samudio, PhD, Kristine R. Broglio, MS, BS, Vivian Ruvolo, Rooha Contractor, Wenjing Chen, MS, Hagop Kantarjian, MD, Michael Andreeff, MD, PhD, Mary A. Weiser, MD, PhD

Blood (2005) 106 (11): 12.

https://doi.org/10.1182/blood.V106.11.12.12

Published: 2005

Journal Articles

Novel Role of HDAC Inhibitors in Bone Marrow Microenvironment: Activation of Leukemia Cell Phagocytosis through Annexin A1.

Yoko Tabe, MD, PhD, Rooha Contractor, Susanne Radke, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2005) 106 (11): 2219.

https://doi.org/10.1182/blood.V106.11.2219.2219

Published: 2005

Journal Articles

Triterpenoid Methyl-CDDO Is a Potent Inducer of Apoptosis in CD34 + AML Progenitor Cells Via Activation of SAPK Pathways and Inhibition of MAPK Cascades.

Marina Konopleva, M.D., Ph.D., Peter Ruvolo, Ph.D., Rooha Contractor, Svitlana Kurinna, Yue-Xi Shi, Teresa McQueen, Michele Milella, M.D., Michael Andreeff, M.D., Ph.D.

Blood (2004) 104 (11): 2533.

https://doi.org/10.1182/blood.V104.11.2533.2533

Published: 2004

Journal Articles

High Glucose Activates AKT Signaling and Induces Upregulation of Genes Encoding Glycolytic Enzymes Glut-1 and HK-2 in Acute Lymphocytic Leukemia.

Daniela Buglio, M.D., Wendy Schober, Rooha Contractor, Teresa McQueen, Zhihong Zeng, M.D., Hagop Kantarjian, M.D., Mary A. Weiser, M.D., Ph.D., Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.

Blood (2004) 104 (11): 2049.

https://doi.org/10.1182/blood.V104.11.2049.2049

Published: 2004

Journal Articles

Histone Deacetylase Inhibitor Depsipeptide (FK228) Induces Apoptosis through Histone Acetylation and Upregulation of Annexin A1 in AML1-ETO Expressing Kasumi-1 Cells.

Yoko Tabe, M.D., Ph.D., Rooha Contractor, Susanne Radke, Ph.D., Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.

Blood (2004) 104 (11): 4343.

https://doi.org/10.1182/blood.V104.11.4343.4343

Published: 2004

Journal Articles

Inhibition of Bcl-2 Signaling at Nanomolar Concentrations by Small Molecule BH3 Inhibitor, ABT-737 as a Novel Therapeutic Strategy in Acute Myeloid Leukemia (AML).

Rooha Contractor, Marina Konopleva, M.D., Ph.D., Xingming Deng, M.D., Ph.D., David Harris, Peter Ruvolo, Ph.D., Zeev Estrov, M.D., W. Stratford May, M.D., Ph.D., Saul H. Rosenberg, Ph.D., Michael Andreeff, M.D., Ph.D.

Blood (2004) 104 (11): 760.

https://doi.org/10.1182/blood.V104.11.760.760

Published: 2004

Journal Articles

A Novel Ring-Substituted Diindolylmethane 1,1-bis [3′-(5-methoxyindolyl)]-1-(p-t-butylphenyl) Methane Abrogates ERK Activation and Induces Apoptosis in Acute Myeloid Leukemia (AML).

Rooha Contractor, Ismael J. Samudio, Ph.D., Zeev Estrov, M.D., David Harris, James A. McCubrey, Ph.D., Stephen H. Safe, Ph.D., Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.

Blood (2004) 104 (11): 3399.

https://doi.org/10.1182/blood.V104.11.3399.3399

Published: 2004

NARROW

Inhibition of Bcl-2 Signaling by Small Molecule BH3 Inhhibitor GX15-070 as a Novel Therapeutic Strategy in AML.

Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

Mechanisms of Apoptosis Induction by BH3 Inhibitor ABT-737 in AML.

Mechanisms and Activity of PPARγ-Active Triterpenoids CDDO and CDDO-Me in Leukemias.

Inhibition of Bcl-2 Signaling by Small Molecule BH3 Inhibitor GX15-070 as a Novel Therapeutic Strategy in AML.

Relationship between m-TOR-Mediated Upregulation of Glycolysis, Chemoresistance, and Prognosis in Patients with ALL.

Novel Role of HDAC Inhibitors in Bone Marrow Microenvironment: Activation of Leukemia Cell Phagocytosis through Annexin A1.

Triterpenoid Methyl-CDDO Is a Potent Inducer of Apoptosis in CD34 + AML Progenitor Cells Via Activation of SAPK Pathways and Inhibition of MAPK Cascades.

High Glucose Activates AKT Signaling and Induces Upregulation of Genes Encoding Glycolytic Enzymes Glut-1 and HK-2 in Acute Lymphocytic Leukemia.

Histone Deacetylase Inhibitor Depsipeptide (FK228) Induces Apoptosis through Histone Acetylation and Upregulation of Annexin A1 in AML1-ETO Expressing Kasumi-1 Cells.

Inhibition of Bcl-2 Signaling at Nanomolar Concentrations by Small Molecule BH3 Inhibitor, ABT-737 as a Novel Therapeutic Strategy in Acute Myeloid Leukemia (AML).

A Novel Ring-Substituted Diindolylmethane 1,1-bis [3′-(5-methoxyindolyl)]-1-(p-t-butylphenyl) Methane Abrogates ERK Activation and Induces Apoptosis in Acute Myeloid Leukemia (AML).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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