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Journal Articles

Expression of CXCR4 and CXCR7 Receptors for Stromal Derived Factor-1 (SDF- 1) Is Differently Regulated in Human Rhabdomyosarcomas (RMS): The Biological Consequences

Maciek Tarnowski, Ph.D., Radoslaw Maksym, Ryan Reca, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D., Magdalena Kucia, Ph.D.

Blood (2008) 112 (11): 4764.

https://doi.org/10.1182/blood.V112.11.4764.4764

Published: 2008

Journal Articles

The Studies in Various Murine Strains with Defects in Activation of Complement Cascade (CC) Reveal Both Pivotal and Pleiotropic Role of CC in Mobilization of Hematopoietic Stem/Progenitor Cells.

Marcin Wysoczynski, Ryan Reca, PhD, Wu Wan, Magda Kucia, PhD, Marina Botto, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2007) 110 (11): 774.

https://doi.org/10.1182/blood.V110.11.774.774

Published: 2007

Journal Articles

Beta Glucan Enhances Hematopoietic Stem Cell Mobilization.

Stephanie Wagner, MD, Daniel Cramer, PhD, Richard Hansen, Ryan Reca, PhD, Mariusz Ratajczak, PhD, Bing Li, PhD, Damian Laber, MD, Jun Yan, MD,PhD

Blood (2006) 108 (11): 1348.

https://doi.org/10.1182/blood.V108.11.1348.1348

Published: 2006

Journal Articles

The CD45 − LIN − Adult Marrow-Derived CXCR4 + SSEA-1 + Oct-4 + Very Small Embryonic-Like (VSEL) Stem Cells Form In Vitro Spheres Which May Differentiate into CD45 + Hematopoietic Cells.

Janina Ratajczak, MD, PhD, Magda Kucia, PhD, Ewa Zuba-Surma, PhD, Ryan Reca, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2006) 108 (11): 280.

https://doi.org/10.1182/blood.V108.11.280.280

Published: 2006

Journal Articles

Mobilization Studies in Immunodeficient Mice Support a Role of Complement in Modulating the Trafficking of Hematopoietic Stem Cells (HSC) - A Pivotal Role of C3 Cleavage Fragments in Retention and C5 Fragments in Mobilization/Egress of HSC.

Ryan Reca, PhD, Marcin Wysoczynski, Kucia Magda, PhD, Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2006) 108 (11): 3375.

https://doi.org/10.1182/blood.V108.11.3375.3375

Published: 2006

Journal Articles

The Unexpected Role of C3a-C3aR Axis in Maturation of Erythroid Cells - Implications for Pathogenesis of Hypoxia-Related Polycythemias.

Janina Ratajczak, MD, PhD, Ryan Reca, PhD, Bogdan Machalinski, MD, PhD, Jaroslaw Maciejewski, MD, PhD, Mary Laughlin, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2006) 108 (11): 651.

https://doi.org/10.1182/blood.V108.11.651.651

Published: 2006

Journal Articles

An Evidence That Murine Marrow-Derived CXCR4 + SSEA-1 + Oct-4 + Very Small Embryonic-Like (VSEL) Stem Cells Are Pluripotent and Express Several Primordial Germ Cell (PGC) Markers - Hypotesis for Developmental Deposition of PGC in Various Organs.

Magda Kucia, PhD, Ewa Zuba-Surma, PhD, Ryan Reca, PhD, Janina Ratajczak, MD, PhD, Mariusz Ratajczak, MD, PhD

Blood (2006) 108 (11): 1676.

https://doi.org/10.1182/blood.V108.11.1676.1676

Published: 2006

Journal Articles

Immunodeficient Mice Are Poor Mobilizers -Novel Evidence That Demonstrates a Pivotal Role of Complement in Triggering Mobilization of HSPC.

Ryan Reca, PhD, Marcin Wysoczynski, Richard Hansen, Magda Kucia, PhD, Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2005) 106 (11): 1976.

https://doi.org/10.1182/blood.V106.11.1976.1976

Published: 2005

Journal Articles

Novel Evidence That Statin-Mediated Perturbation of Lipid Raft Formation Ameliorates Bleeding- Related Thrombocytosis.

Marcin Wysoczynski, Ryan Reca, PhD, Magda Kucia, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2005) 106 (11): 2164.

https://doi.org/10.1182/blood.V106.11.2164.2164

Published: 2005

Journal Articles

LIF-LIF-R and SDF-1-CXCR4 Axes Regulate Overlapping and Complementary Steps of Metastasis of Rhabdomyosarcoma - Implication for Developing Better Antimetastatic Therapies.

Kasia Miekus, Marcin Wysoczynski, Ryan Reca, MD, PhD, Gozdzik Jolanta, MD, PhD, Bertolone J. Salvatore, MD, Anna Janowska-Wieczorek, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2005) 106 (11): 2296.

https://doi.org/10.1182/blood.V106.11.2296.2296

Published: 2005

Journal Articles

A Population of Small CXCR4 + SSEA-1 + Oct-4 + Embryonic-Like Stem Cells Identified in Adult Bone Marrow.

Magda Kucia, PhD, Ryan Reca, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD.

Blood (2005) 106 (11): 3623.

https://doi.org/10.1182/blood.V106.11.3623.3623

Published: 2005

Journal Articles

Defective Engraftment of HSPC from C3aR −/ − Mice Reveals an Underappreciated Role of C3a-C3aR Axis in Stem Cell Homing to Bone Marrow.

Ryan Reca, PhD, Magda Kucia, PhD, Jarek Baran, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2005) 106 (11): 1259.

https://doi.org/10.1182/blood.V106.11.1259.1259

Published: 2005

Journal Articles

Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

Marcin Wysoczynski, Ryan Reca, Janina Ratajczak, Magda Kucia, Neeta Shirvaikar, Marek Honczarenko, Michael Mills, Jens Wanzeck, Anna Janowska-Wieczorek, Mariusz Z. Ratajczak

Blood (2005) 105 (1): 40–48.

https://doi.org/10.1182/blood-2004-04-1430

Published: 2005

Journal Articles

CXCR4 Is a PAX Family Transcription Factor Regulated Gene.

Ryan Reca, Kacper Jankowski, Grzegorz Przybylski, MD, PhD, Anna Janowska-Wieczorek, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2004) 104 (11): 4205.

https://doi.org/10.1182/blood.V104.11.4205.4205

Published: 2004

Journal Articles

More Evidence That the Phenomenon of “Plasticity” of Hematopoietic Stem Cells (HSC) and Potential Involvement of BM-Derived Cells in Organ Regeneration Could Be Explained by the Presence of a Heterogenous Population of Tissue Committed Stem Cells (TCSC) Residing/Hiding out in Bone Marrow.

Magda Kucia, PhD, Marcin Wysoczynski, Ryan Reca, Marcin Majka, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2004) 104 (11): 4173.

https://doi.org/10.1182/blood.V104.11.4173.4173

Published: 2004

Journal Articles

The Novel Role of the Third Complement Component (C3) in Megakaryopoiesis: Implications for Pathogenesis of Reactive Thrombocytosis.

Marcin Wysoczynski, Ryan Reca, Magda Kucia, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2004) 104 (11): 2906.

https://doi.org/10.1182/blood.V104.11.2906.2906

Published: 2004

Journal Articles

A Potential New Application of Mobilization/Leukapheresis for Enrichment of Peripheral Blood in Circulating Non-Hematopoietic CXCR4 + CD45 − Tissue-Committed Stem Cells (TCSC) for Organ/Tissue Regeneration.

Magda Kucia, PhD, Ryan Reca, Marcin Wysoczynski, Jolanta Gozdzik, MD, PhD, Janina Ratajczak, MD, PhD, Anna Janowska-Wieczorek, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2004) 104 (11): 151.

https://doi.org/10.1182/blood.V104.11.151.151

Published: 2004

Journal Articles

Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

Janina Ratajczak, Ryan Reca, Magda Kucia, Marcin Majka, Daniel J. Allendorf, Jarek T. Baran, Anna Janowska-Wieczorek, Rick A. Wetsel, Gordon D. Ross, Mariusz Z. Ratajczak

Blood (2004) 103 (6): 2071–2078.

https://doi.org/10.1182/blood-2003-06-2099

Published: 2004

Journal Articles

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

Ryan Reca, Dimitrios Mastellos, Marcin Majka, Leah Marquez, Janina Ratajczak, Silvia Franchini, Aleksandra Glodek, Marek Honczarenko, Lynn A. Spruce, Anna Janowska-Wieczorek, John D. Lambris, Mariusz Z. Ratajczak

Blood (2003) 101 (10): 3784–3793.

https://doi.org/10.1182/blood-2002-10-3233

Published: 2003

Journal Articles

Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment

Anna Janowska-Wieczorek, Marcin Majka, Jacek Kijowski, Monika Baj-Krzyworzeka, Ryan Reca, A. Robert Turner, Janina Ratajczak, Steven G. Emerson, M. Anna Kowalska, Mariusz Z. Ratajczak

Blood (2001) 98 (10): 3143–3149.

https://doi.org/10.1182/blood.V98.10.3143

Published: 2001

NARROW

Expression of CXCR4 and CXCR7 Receptors for Stromal Derived Factor-1 (SDF- 1) Is Differently Regulated in Human Rhabdomyosarcomas (RMS): The Biological Consequences

The Studies in Various Murine Strains with Defects in Activation of Complement Cascade (CC) Reveal Both Pivotal and Pleiotropic Role of CC in Mobilization of Hematopoietic Stem/Progenitor Cells.

Beta Glucan Enhances Hematopoietic Stem Cell Mobilization.

The CD45 − LIN − Adult Marrow-Derived CXCR4 + SSEA-1 + Oct-4 + Very Small Embryonic-Like (VSEL) Stem Cells Form In Vitro Spheres Which May Differentiate into CD45 + Hematopoietic Cells.

Mobilization Studies in Immunodeficient Mice Support a Role of Complement in Modulating the Trafficking of Hematopoietic Stem Cells (HSC) - A Pivotal Role of C3 Cleavage Fragments in Retention and C5 Fragments in Mobilization/Egress of HSC.

The Unexpected Role of C3a-C3aR Axis in Maturation of Erythroid Cells - Implications for Pathogenesis of Hypoxia-Related Polycythemias.

An Evidence That Murine Marrow-Derived CXCR4 + SSEA-1 + Oct-4 + Very Small Embryonic-Like (VSEL) Stem Cells Are Pluripotent and Express Several Primordial Germ Cell (PGC) Markers - Hypotesis for Developmental Deposition of PGC in Various Organs.

Immunodeficient Mice Are Poor Mobilizers -Novel Evidence That Demonstrates a Pivotal Role of Complement in Triggering Mobilization of HSPC.

Novel Evidence That Statin-Mediated Perturbation of Lipid Raft Formation Ameliorates Bleeding- Related Thrombocytosis.

LIF-LIF-R and SDF-1-CXCR4 Axes Regulate Overlapping and Complementary Steps of Metastasis of Rhabdomyosarcoma - Implication for Developing Better Antimetastatic Therapies.

A Population of Small CXCR4 + SSEA-1 + Oct-4 + Embryonic-Like Stem Cells Identified in Adult Bone Marrow.

Defective Engraftment of HSPC from C3aR −/ − Mice Reveals an Underappreciated Role of C3a-C3aR Axis in Stem Cell Homing to Bone Marrow.

Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

CXCR4 Is a PAX Family Transcription Factor Regulated Gene.

More Evidence That the Phenomenon of “Plasticity” of Hematopoietic Stem Cells (HSC) and Potential Involvement of BM-Derived Cells in Organ Regeneration Could Be Explained by the Presence of a Heterogenous Population of Tissue Committed Stem Cells (TCSC) Residing/Hiding out in Bone Marrow.

The Novel Role of the Third Complement Component (C3) in Megakaryopoiesis: Implications for Pathogenesis of Reactive Thrombocytosis.

A Potential New Application of Mobilization/Leukapheresis for Enrichment of Peripheral Blood in Circulating Non-Hematopoietic CXCR4 + CD45 − Tissue-Committed Stem Cells (TCSC) for Organ/Tissue Regeneration.

Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment

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American Society of Hematology

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ASH Publications

American Society of Hematology

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