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Ryan Yen
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Journal Articles

Identification of Multivariable microRNA and Clinical Biomarkers Panels to Predict Imatinib Response in Chronic Myeloid Leukemia at Diagnosis

Andrew Wu, Ryan Yen, Sarah Grasedieck, Hanyang Lin, Helen Nakamoto, Donna L. Forrest, Connie J. Eaves, Xiaoyan Jiang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4547.
https://doi.org/10.1182/blood-2023-180252
Published: 2023
Journal Articles

Targeting a Highly Deregulated eIF4F Translation Initiation Complex Sensitises IM-Resistant Cells to Tyrosine Kinase Inhibitors and Effectively Suppresses BCR-ABL1 Protein Expression

Ryan Yen, Lambert Yue, Steven Pelech, Xiaoyan Jiang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3864.
https://doi.org/10.1182/blood-2022-167088
Published: 2022
Journal Articles

Identification of Key microRNAs As Predictive Biomarkers of Nilotinib Response in Chronic Myeloid Leukemia: A Sub-Analysis of the Enestxtnd Clinical Trial

Andrew Wu, Ryan Yen, Sarah Grasedieck, Hanyang Lin, Jiechuang Su, Katharina Rothe, Helen Nakamoto, Donna L. Forrest, Connie J. Eaves, Xiaoyan Jiang
Journal: Blood
Blood (2022) 140 (Supplement 1): 12169–12170.
https://doi.org/10.1182/blood-2022-168534
Published: 2022
Journal Articles

Identification of a Highly Deregulated eIF4F Translation Initiation Complex in Drug-Resistant BCR-ABL + Cells By a Phospho-Proteomic Antibody Microarray

Ryan Yen, Lambert Yue, Steven Pelech, Xiaoyan Jiang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3583.
https://doi.org/10.1182/blood-2021-149185
Published: 2021
Journal Articles

Inhibition of PAK6-Mediated Survival and Cell Cycle Controls Selectively Targets Therapy-Resistant CML Stem/Progenitor Cells

Andrew Wu, BSc, Min Chen, PhD, Ryan Yen, BSc, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-140459
Published: 2020
Journal Articles

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Hanyang Lin, Katharina Rothe, Min Chen, Andrew Wu, Artem Babaian, Ryan Yen, Jonathan Zeng, Jens Ruschmann, Oleh I. Petriv, Kieran O'Neill, Tobias Maetzig, David J. H. F. Knapp, Naoto Nakamichi, Ryan Brinkman, Inanc Birol, Donna L. Forrest, Carl Hansen, R. Keith Humphries, Connie J. Eaves, Xiaoyan Jiang
Journal: Blood
Blood (2020) 136 (5): 596–609.
https://doi.org/10.1182/blood.2019003636
Published: 2020
Includes: Supplemental data
Journal Articles

The AHI-1-BCR-ABL-DNM2 Complex Mediates Mitochondrial Dynamics in Drug-Resistant BCR-ABL + Cells

Ryan Yen, BSc, Lambert Yue, BSc, Steven Pelech, PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 189.
https://doi.org/10.1182/blood-2019-128712
Published: 2019
Journal Articles

Inhibition of the MiR-185-PAK6-Mediated Survival and Metabolic Pathways Selectively Targets Drug-Resistant CML Stem/Progenitor Cells

Andrew Wu, BSc, Katharina Rothe, PhD, Min Chen, PhD, Hanyang Lin, PhD, Artem Babaian, PhD, Ryan Yen, BSc, Donna L. Forrest, MD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4138.
https://doi.org/10.1182/blood-2019-127826
Published: 2019