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S.-W. Grace Cheng
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Journal Articles

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis

Tobias Berg, Silvia Thoene, Damian Yap, Tracee Wee, Nathalie Schoeler, Patty Rosten, Emilia Lim, Misha Bilenky, Andrew J. Mungall, Thomas Oellerich, Sherry Lee, Courteney K. Lai, Patricia Umlandt, Anisa Salmi, Harry Chang, Lisa Yue, David Lai, S.-W. Grace Cheng, Ryan D. Morin, Martin Hirst, Hubert Serve, Marco A. Marra, Gregg B. Morin, Randy D. Gascoyne, Samuel A. Aparicio, R. Keith Humphries
Journal: Blood
Blood (2014) 123 (25): 3914–3924.
https://doi.org/10.1182/blood-2012-12-473439
Published: 2014
Includes: Supplemental data
Journal Articles

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

Damian B. Yap, Justin Chu, Tobias Berg, Matthieu Schapira, S.-W. Grace Cheng, Annie Moradian, Ryan D. Morin, Andrew J. Mungall, Barbara Meissner, Merrill Boyle, Victor E. Marquez, Marco A. Marra, Randy D. Gascoyne, R. Keith Humphries, Cheryl H. Arrowsmith, Gregg B. Morin, Samuel A. J. R. Aparicio
Journal: Blood
Blood (2011) 117 (8): 2451–2459.
https://doi.org/10.1182/blood-2010-11-321208
Published: 2011
Includes: Supplemental data