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Gregg B. Morin
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Journal Articles

UBR5 Mutations in Mantle Cell Lymphoma Lead to Increased Proliferation through a Cyclin D1-Dependent Mechanism

Olga Kutovaya, PhD, Stacy Hung, Elena Viganò, PhD, Adele Telenius, Bruce W Woolcock, Barbara Meissner, PhD, Shane Colborne, BSc, Randy D. Gascoyne, MD, Diego Villa, MD, Ryan D. Morin, PhD, BSc, MSc, David W. Scott, PhD MD, FRACP, FRCPA, Gregg B Morin, PhD, Christian Steidl, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2849.
https://doi.org/10.1182/blood-2018-99-118524
Published: 2018
Journal Articles

Functional Investigation of the Gene NFKBIZ and the Impact of 3'UTR Mutations in Diffuse Large B-Cell Lymphoma

Sarah E Arthur, BSc, Anja Mottok, MD PhD, Miguel Alcaide, PhD, Christopher Rushton, BSc, Bruno M. Grande, BSc, Daisuke Ennishi, MDPhD, Jordan Davidson, BSc, Kevin R Bushell, BSc, MSc, Randy D. Gascoyne, MD, Marco A Marra, PhD, Joseph M Connors, MD, Gregg B Morin, PhD, David W. Scott, MD PhD FRACP, FRCPA, Christian Steidl, MD, Ryan D. Morin, PhDBSc,MSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 1228.
https://doi.org/10.1182/blood.V130.Suppl_1.1228.1228
Published: 2017
Journal Articles

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis

Tobias Berg, Silvia Thoene, Damian Yap, Tracee Wee, Nathalie Schoeler, Patty Rosten, Emilia Lim, Misha Bilenky, Andrew J. Mungall, Thomas Oellerich, Sherry Lee, Courteney K. Lai, Patricia Umlandt, Anisa Salmi, Harry Chang, Lisa Yue, David Lai, S.-W. Grace Cheng, Ryan D. Morin, Martin Hirst, Hubert Serve, Marco A. Marra, Gregg B. Morin, Randy D. Gascoyne, Samuel A. Aparicio, R. Keith Humphries
Journal: Blood
Blood (2014) 123 (25): 3914–3924.
https://doi.org/10.1182/blood-2012-12-473439
Published: 2014
Includes: Supplemental data
Journal Articles

Characterization Of The Effects Of Mutated EZH2 On Expression and Epigenome In a Mouse Lymphoma Model

Tobias Berg, MD, Silvia Thoene, PhD, Damian Yap, PhD, Tracee Wee, Nathalie Schoeler, Patty Rosten, Emilia Lim, Misha Bilenky, Andrew J Mungall, Ph.D., Thomas Oellerich, Patricia Umlandt, Anisa Salmi, Harry Chang, Lisa Yue, David Lai, Grace Cheng, PhD, Hubert Serve, MD, Ryan D Morin, Martin Hirst, Marco A. Marra, PhD, Gregg B. Morin, PhD, Randy D. Gascoyne, MD, Samuel A. Aparicio, PhD, R. Keith Humphries, PhD
Journal: Blood
Blood (2013) 122 (21): 346.
https://doi.org/10.1182/blood.V122.21.346.346
Published: 2013
Journal Articles

Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL + Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors

Xiaohu Liu, Min Chen, PhD, Paolo Lobo, Jianghong An, Ph.D., SW. Grace Cheng, Annie Moradian, Gregg B. Morin, PhD, Filip Van Petegem, PhD, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 966.
https://doi.org/10.1182/blood.V118.21.966.966
Published: 2011
Journal Articles

Mutated EZH2 Collaborates with Myc in Inducing Lymphoma in a Mouse Model

Tobias Berg, MD, Damian Yap, PhD, Silvia Thoene, PhD, Tracee Wee, Nathalie Schoeler, Patricia Umlandt, Harry Chang, Lisa Yue, David Lai, Grace Cheng, PhD, Ryan D Morin, M.Sc., Martin Hirst, Marco A. Marra, PhD, Gregg B. Morin, PhD, Randy D. Gascoyne, MD, Samuel A. Aparicio, PhD, R. Keith Humphries, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 227.
https://doi.org/10.1182/blood.V118.21.227.227
Published: 2011
Journal Articles

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

Damian B. Yap, Justin Chu, Tobias Berg, Matthieu Schapira, S.-W. Grace Cheng, Annie Moradian, Ryan D. Morin, Andrew J. Mungall, Barbara Meissner, Merrill Boyle, Victor E. Marquez, Marco A. Marra, Randy D. Gascoyne, R. Keith Humphries, Cheryl H. Arrowsmith, Gregg B. Morin, Samuel A. J. R. Aparicio
Journal: Blood
Blood (2011) 117 (8): 2451–2459.
https://doi.org/10.1182/blood-2010-11-321208
Published: 2011
Includes: Supplemental data
Journal Articles

Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

Brief Report
Richard C. Allsopp, Gregg B. Morin, Ronald DePinho, Calvin B. Harley, Irving L. Weissman
Journal: Blood
Blood (2003) 102 (2): 517–520.
https://doi.org/10.1182/blood-2002-07-2334
Published: 2003