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Spurthi Patil
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Journal Articles

Functional and Multi-Omics Signatures of Mitapivat Efficacy upon Activation of Pyruvate Kinase in Red Blood Cells from Patients with Sickle Cell Disease

Angelo D'Alessandro, Kang Le, Maureen Lundt, Quan Li, Emily Dunkelberger, Troy Cellmer, Andrew J Worth, Spurthi Patil, Chris Huston, Abby Grier, Monika monikA.dzieciatkow, Daniel Stephenson, William A Eaton, Swee Lay Thein
Journal: Blood
Blood (2023) 142 (Supplement 1): 2485.
https://doi.org/10.1182/blood-2023-181213
Published: 2023
Journal Articles

A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study of Mitapivat in Patients with Sickle Cell Disease: RISE UP Phase 2 Results

Modupe Idowu, Lucas Otieno, Bogdan Dumitriu, Clarisse LC Lobo, Swee Lay Thein, Biree Andemariam, Obiageli E Nnodu, Adlette Inati, Alexander K Glaros, Sara Teresinha Olalla Saad, Pablo Bartolucci, Raffaella Colombatti, Ali T Taher, Miguel R Abboud, Abdulafeez Oluyadi, Varsha Iyer, Ophelia Yin, Susan Morris, Amber M Yates, Hui Shao, Spurthi Patil, Rolandas Urbstonaitis, Ahmar U Zaidi, Wally R Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 271.
https://doi.org/10.1182/blood-2023-187033
Published: 2023
Journal Articles

Results from the Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers

Xiaoshu Dai Gurov, Elizabeth Merica, Varsha Iyer, Annie Claeys, Spurthi Patil, Rolandas Urbstonaitis, James Xiao, Michael U. Callaghan
Journal: Blood
Blood (2022) 140 (Supplement 1): 5426–5427.
https://doi.org/10.1182/blood-2022-157719
Published: 2022