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Journal Articles

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Anna L. Brown, PhD BSc, Mark Armstrong, MSc, David Lawrence, Paul Wang, Peer Arts, PhD, Nicolas Duployez, PharmD, PhD, Jane Churpek, MD, Kiran Tawana, MD, Erin Degelman, MSc, BSc, Georges Natsoulis, PhD, Monica L. Guzman, PhD, Mrinal M. Patnaik, MD MBBS, Akiko Shimamura, MD PhD, Alan B. Cantor, MD PhD, Tim Ripperger, MD PhD, Brigitte Schlegelberger, MD PhD, Doris Steinemann, PhD, Courtney D. DiNardo, MD MSc, Cristina Mecucci, MD PhD, Elvira DRP Velloso, MD PhD, Fabio PS Santos, MD, Marcela CA Silva, Uma Borate, MD, Shannon K. McWeeney, PhD, Grzegorz Nalepa, MD PhD, Susanne Ragg, MD PhD, Erika Mijin Kwon, PhD, Anupriya Agarwal, PhD, Stephen Langabeer, PhD, Jeffery M. Klco, MD PhD, Jun J. Yang, PhD, Cecily Forsyth, FRACP, FRCPA, MBBS, Sally Mapp, MD PhD, Helen Mar Fan, MD, Lesley Rawlings, PhD, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Andrew H Wei, MBBS,PhD, Inderjeet Dokal, MD, Tom Vulliamy, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Deepak Singhal, MBBS, MD FRACP, FRCPA, Susan Branford, PhD, Elli Papaemmanuil, PhD, Jean Soulier, MDPhD, Stefan Fröhling, MD, Alwin Kramer, MD, Guy Sauvageau, MD PhD, Neil Morgan, Carolyn Owen, Csaba Bödör, PhD, Jude Fitzgibbon, Hugh Y. Rienhoff, Jr., MD, Mineo Kurokawa, MD PhD, Lucy Godley, MD PhD, Claude Preudhomme, Paul P Liu, MD PhD, Nicola Poplawski, MD, Christopher N. Hahn, PhD, Hamish S. Scott, PhD

Blood (2018) 132 (Supplement 1): 5241.

https://doi.org/10.1182/blood-2018-99-118017

Published: 2018

Journal Articles

Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDH mut -Driven DNA Hypermethylation in AML Stem Cells

Blood (2017) 130 (Supplement 1): 472.

https://doi.org/10.1182/blood.V130.Suppl_1.472.472

Published: 2017

Journal Articles

The RET Receptor Tyrosine Kinase Promotes Acute Myeloid Leukemia through Protection of FLT3-ITD Mutants from Autophagic Degradation

Saskia Rudat, MSc, Anja Pfaus, MSc, Claudia Bühler, MD, Sophie Rabe, MSc, Lars Bullinger, MD, Stefan Gröschel, MD, Stephen M. Sykes, PhD, Michael D. Milsom, PhD, Jana M. Ellegast, MD, Stefan Fröhling, MD, Claudia Scholl, MD

Blood (2016) 128 (22): 2849.

https://doi.org/10.1182/blood.V128.22.2849.2849

Published: 2016

Journal Articles

CDK4/6 Inhibitor Palbociclib for Treatment of KMT2A -Rearranged Acute Myeloid Leukemia: Interim Analysis of the AMLSG 23-14 Trial

Stefan Fröhling, MD, Mridul Agrawal, MD, Nikolaus Jahn, MD, Lars R. Fransecky, MD, Claudia D. Baldus, MD, Ralph Wäsch, MD, Michael Lübbert, MD, Gina Walter, PhD, Patrizia Jensen, Claudia Scholl, MD, Marianne Habdank, Konstanze Döhner, Hartmut Döhner, MD, Richard F. Schlenk, MD

Blood (2016) 128 (22): 1608.

https://doi.org/10.1182/blood.V128.22.1608.1608

Published: 2016

Journal Articles

Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline RUNX1 Mutations

Anna L Brown, PhD, Christopher N Hahn, PhD, Catherine Carmichael, Ella Wilkins, Milena Babic, BMPharBio (Hons), Chan-Eng Chong, PhD, Xiao-Chun Li, Joelle Michaud, Ping Cannon, Nicola Poplawski, MBChB, DipPaed, FRACP, MD, Meryl Altree, Kerry Phillips, Louise Jaensch, Miriam Fine, Andreas W Schreiber, PhD, Jinghua Feng, PhD, Lesley Rawlings, PhD, Cassandra Vakulin, Carolyn Butcher, Richard D'Andrea, PhD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Nigel Patton, Cecily Forsyth, MBBS, FRACP, FRCPA, Sally Mapp, PhD MD, Helen Mar Fan, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Julian Cooney, MD, Mark S Currie, MD, Uday R. Popat, MD, Kenneth Bradstock, MBBS, PhD, April D. Sorrell, MD, Carolyn J. Owen, MD MDes(UK), FRCPC, Marshall S Horwitz, MD PhD, Devendra Hiwase, MBBS, FRACP, FRCPA, MD PhD, Alwin Krämer, MD, Stefan Fröhling, MD, Lucy A Godley, MD PhD, Jane E Churpek, MD, Hamish S Scott, BSc, PhD FFSc (RCPA), FAHMS

Blood (2016) 128 (22): 1212.

https://doi.org/10.1182/blood.V128.22.1212.1212

Published: 2016

Journal Articles

Cdx2 Cooperates with Flt3-ITD to Induce Acute Myeloid Leukaemia in Mice

Therese Vu, BSc, Claudia Bruedigam, Axia Song, Solene Guignes, Rebecca Austin, Sebastien Jacquelin, Alistair Chalk, Carl Walkley, PhD BPharm, Claudia Scholl, Stefan Fröhling, MD, Steven W. Lane, MD

Blood (2015) 126 (23): 557.

https://doi.org/10.1182/blood.V126.23.557.557

Published: 2015

Journal Articles

Requirement For CDK6 In MLL-Rearranged Acute Myeloid Leukemia

Theresa Placke, PhD, Katrin Faber, PhD, Atsushi Nonami, MD, Helmut R. Salih, MD, Stephen M. Sykes, PhD, David E. Root, PhD, David A. Barbie, MD, William C. Hahn, MD, PhD, Michael D. Milsom, PhD, Claudia Scholl, MD, Stefan Fröhling, MD

Blood (2013) 122 (21): 3782.

https://doi.org/10.1182/blood.V122.21.3782.3782

Published: 2013

Journal Articles

Prognostic Impact of BAALC Expression in the Context of Other Molecular Markers in Cytogenetically Normal Acute Myeloid Leukemia.

Konstanze Dohner, MD, Andrea Corbacioglu, PhD, Karina Eiwen, Judith Ewert, Stefan Frohling, MD, Lars Bullinger, MD, Juergen Krauter, MD, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Hartmut Dohner, MD, Richard F. Schlenk, MD

Blood (2007) 110 (11): 3485.

https://doi.org/10.1182/blood.V110.11.3485.3485

Published: 2007

Journal Articles

Gene Mutations as Predicitive Markers for Postremission Therapy in Younger Adults with Normal Karyotype AML.

Richard F. Schlenk, MD, Andrea Corbacioglu, MD, Jürgen Krauter, MD, Lars Bullinger, MD, Michael Morgan, MD, Daniela Späth, MD, Irina Schäfer, MD, Stefan Frohling, MD, Arnold Ganser, MD, Hartmut Dohner, MD, Konstanze Dohner, MD

Blood (2006) 108 (11): 4.

https://doi.org/10.1182/blood.V108.11.4.4

Published: 2006

Journal Articles

Characterization of NPM1 -Mutated/ FLT3 ITD-Negative Acute Myeloid Leukemia with Normal Karyotype by Gene Expression Profiling.

Lars Bullinger, MD, Konstanze Dohner, MD, Raphael Kranz, Frank G. Rucker, MD, Stefan Frohling, MD, Richard F. Schlenk, MD, Jonathan R. Pollack, MD, PhD, Hartmut Dohner, MD

Blood (2006) 108 (11): 155.

https://doi.org/10.1182/blood.V108.11.155.155

Published: 2006

Journal Articles

Minimal Residual Disease (MRD) Monitoring in CBFB-MYH11 Acute Myeloid Leukemia (AML) Is of Prognostic Relevance for Relapse-Free Survival.

Andrea Corbacioglu, PhD, Claudia Scholl, MD, Karina Eiwen, Lars Bullinger, MD, Stefan Frohling, MD, Hartmut Dohner, MD, Richard F. Schlenk, MD, Konstanze Dohner, MD

Blood (2006) 108 (11): 2298.

https://doi.org/10.1182/blood.V108.11.2298.2298

Published: 2006

Journal Articles

A FLT3 Gene-Expression Signature Outperforms FLT3 Status in Predicting Clinical Outcome for Patients with Normal Karyotype AML.

Lars Bullinger, MD, Konstanze Dohner, MD, Christoph Stirner, Frank G. Rucker, MD, Stefan Frohling, MD, Young H. Kim, Richard F. Schlenk, MD, Robert Tibshirani, PhD, Hartmut Dohner, MD, Jonathan R. Pollack, MD, PhD

Blood (2006) 108 (11): 2311.

https://doi.org/10.1182/blood.V108.11.2311.2311

Published: 2006

Journal Articles

Gene Expression Profiling Identifies Distinct Subclasses in Core Binding Factor Acute Myeloid Leukemia.

Lars Bullinger, MD, Stephan Kurz, Konstanze Dohner, MD, Claudia Scholl, MD, Stefan Frohling, MD, Richard F. Schlenk, MD, Hartmut Dohner, MD, Jonathan R. Pollack, MD, PhD

Blood (2005) 106 (11): 673.

https://doi.org/10.1182/blood.V106.11.673.673

Published: 2005

Journal Articles

Prognostic Gene-Expression Signatures in Adult Acute Myeloid Leukemia with Normal Karyotype.

Lars Bullinger, MD, Eric Bair, PhD, Raphael Kranz, Konstanze Dohner, MD, Stefan Frohling, MD, Richard F. Schlenk, MD, Robert Tibshirani, PhD, Hartmut Dohner, MD, Jonathan R. Pollack, MD, PhD

Blood (2005) 106 (11): 756.

https://doi.org/10.1182/blood.V106.11.756.756

Published: 2005

Journal Articles

MLL/AF9 Fusion Transcript Quantification in t(9;11)-Positive AML Identify Patients with High Risk of Relapse.

Claudia Scholl, MD, Karina Eiwen, Stefan Frohling, MD, Richard F. Schlenk, MD, Hartmut Dohner, MD, Konstanze Dohner, MD

Blood (2004) 104 (11): 3015.

https://doi.org/10.1182/blood.V104.11.3015.3015

Published: 2004

Journal Articles

Identification of Distinct inv(16) Subclasses in Adult Acute Myeloid Leukemia Based on Gene Expression Profiling.

Lars Bullinger, MD, Claudia Scholl, MD, Eric Bair, Konstanze Dohner, MD, Stefan Frohling, MD, Richard F. Schlenk, MD, Robert Tibshirani, PhD, Hartmut Dohner, MD, Jonathan R. Pollack, MD, PhD

Blood (2004) 104 (11): 2037.

https://doi.org/10.1182/blood.V104.11.2037.2037

Published: 2004

Journal Articles

Identification of Genomic Imbalances in AML with Complex Karyotype Using Matrix-Based Comparative Genomic Hybridization.

Frank G. Rucker, Carsten Schwanen, MD, Daniel Lipka, Swen Wessendorf, MD, Stefan Frohling, MD, Hans Kestler, Peter Lichter, PhD, Martin Bentz, MD, Konstanze Dohner, MD, Hartmut Dohner, MD

Blood (2004) 104 (11): 3382.

https://doi.org/10.1182/blood.V104.11.3382.3382

Published: 2004

NARROW

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDH mut -Driven DNA Hypermethylation in AML Stem Cells

The RET Receptor Tyrosine Kinase Promotes Acute Myeloid Leukemia through Protection of FLT3-ITD Mutants from Autophagic Degradation

CDK4/6 Inhibitor Palbociclib for Treatment of KMT2A -Rearranged Acute Myeloid Leukemia: Interim Analysis of the AMLSG 23-14 Trial

Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline RUNX1 Mutations

Cdx2 Cooperates with Flt3-ITD to Induce Acute Myeloid Leukaemia in Mice

Requirement For CDK6 In MLL-Rearranged Acute Myeloid Leukemia

Prognostic Impact of BAALC Expression in the Context of Other Molecular Markers in Cytogenetically Normal Acute Myeloid Leukemia.

Gene Mutations as Predicitive Markers for Postremission Therapy in Younger Adults with Normal Karyotype AML.

Characterization of NPM1 -Mutated/ FLT3 ITD-Negative Acute Myeloid Leukemia with Normal Karyotype by Gene Expression Profiling.

Minimal Residual Disease (MRD) Monitoring in CBFB-MYH11 Acute Myeloid Leukemia (AML) Is of Prognostic Relevance for Relapse-Free Survival.

A FLT3 Gene-Expression Signature Outperforms FLT3 Status in Predicting Clinical Outcome for Patients with Normal Karyotype AML.

Gene Expression Profiling Identifies Distinct Subclasses in Core Binding Factor Acute Myeloid Leukemia.

Prognostic Gene-Expression Signatures in Adult Acute Myeloid Leukemia with Normal Karyotype.

MLL/AF9 Fusion Transcript Quantification in t(9;11)-Positive AML Identify Patients with High Risk of Relapse.

Identification of Distinct inv(16) Subclasses in Adult Acute Myeloid Leukemia Based on Gene Expression Profiling.

Identification of Genomic Imbalances in AML with Complex Karyotype Using Matrix-Based Comparative Genomic Hybridization.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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