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Journal Articles

A phase 3 randomized trial of mavorixafor, a CXCR4 antagonist, for WHIM syndrome

Blood (2024) 144 (1): 35–45.

https://doi.org/10.1182/blood.2023022658

Published: 2024

Includes: Supplemental data

Journal Articles

Plasma Proteome Profiling of Sickle Cell Patients Reveals Activation of Inflammatory Pathways during Steady State and Vaso-Occlusive Crisis

Lydian A. de Ligt, Aafke E. Gaartman, Kadère Konté, Taco W. Kuijpers, Karin Fijnvandraat, Bart J. Biemond, Robin van Bruggen, Erfan Nur

Blood (2023) 142 (Supplement 1): 1108.

https://doi.org/10.1182/blood-2023-179239

Published: 2023

Journal Articles

IL-7 receptor signaling drives human B-cell progenitor differentiation and expansion

Fabian M. P. Kaiser, Iga Janowska, Roberta Menafra, Melanie de Gier, Jakov Korzhenevich, Ingrid Pico-Knijnenburg, Indu Khatri, Ansgar Schulz, Taco W. Kuijpers, Arjan C. Lankester, Lukas Konstantinidis, Miriam Erlacher, Susan Kloet, Pauline A. van Schouwenburg, Marta Rizzi, Mirjam van der Burg

Blood (2023) 142 (13): 1113–1130.

https://doi.org/10.1182/blood.2023019721

Published: 2023

Includes: Supplemental data

Journal Articles

Pleiotropic Effects of Hydroxyurea on Red Blood Cell and Neutrophil Phenotype in Patients with Sickle Cell Disease; Data from the Notice Study

Aafke E. Gaartman, Lydian A. de Ligt, Anton T.J. Tool, Boukje M. Beuger, Martijn Veldthuis, Taco W. Kuijpers, Rob van Zwieten, Bart J. Biemond, Robin Van Bruggen, Erfan Nur

Blood (2022) 140 (Supplement 1): 2551–2553.

https://doi.org/10.1182/blood-2022-169070

Published: 2022

Journal Articles

Formation of neutrophil extracellular traps requires actin cytoskeleton rearrangements

Evelien G. G. Sprenkeler, Anton T. J. Tool, Stefanie S. V. Henriet, Robin van Bruggen, Taco W. Kuijpers

Blood (2022) 139 (21): 3166–3180.

https://doi.org/10.1182/blood.2021013565

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Global Phase 3, Randomized, Placebo-Controlled Trial with Open-Label Extension Evaluating the Oral CXCR4 Antagonist Mavorixafor in Patients with WHIM Syndrome (4WHIM): Trial Design and Enrollment

Blood (2021) 138 (Supplement 1): 4310.

https://doi.org/10.1182/blood-2021-153346

Published: 2021

Journal Articles

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome

Matthew C. Sims, Louisa Mayer, Janine H. Collins, Tadbir K. Bariana, Karyn Megy, Cecile Lavenu-Bombled, Denis Seyres, Laxmikanth Kollipara, Frances S. Burden, Daniel Greene, Dave Lee, Antonio Rodriguez-Romera, Marie-Christine Alessi, William J. Astle, Wadie F. Bahou, Loredana Bury, Elizabeth Chalmers, Rachael Da Silva, Erica De Candia, Sri V. V. Deevi, Samantha Farrow, Keith Gomez, Luigi Grassi, Andreas Greinacher, Paolo Gresele, Dan Hart, Marie-Françoise Hurtaud, Anne M. Kelly, Ron Kerr, Sandra Le Quellec, Thierry Leblanc, Eva B. Leinøe, Rutendo Mapeta, Harriet McKinney, Alan D. Michelson, Sara Morais, Diane Nugent, Sofia Papadia, Soo J. Park, John Pasi, Gian Marco Podda, Man-Chiu Poon, Rachel Reed, Mallika Sekhar, Hanna Shalev, Suthesh Sivapalaratnam, Orna Steinberg-Shemer, Jonathan C. Stephens, Robert C. Tait, Ernest Turro, John K. M. Wu, Barbara Zieger, NIHR BioResource, Taco W. Kuijpers, Anthony D. Whetton, Albert Sickmann, Kathleen Freson, Kate Downes, Wendy N. Erber, Mattia Frontini, Paquita Nurden, Willem H. Ouwehand, Remi Favier, Jose A. Guerrero

Blood (2020) 136 (17): 1956–1967.

https://doi.org/10.1182/blood.2019004776

Published: 2020

Includes: Supplemental data

Journal Articles

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

Blood (2020) 135 (24): 2171–2181.

https://doi.org/10.1182/blood.2019002633

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis

Blood (2018) 131 (7): 830–835.

https://doi.org/10.1182/blood-2017-07-796151

Published: 2018

Includes: Supplemental data

Journal Articles

Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease

Sanne M. Meinderts, Joep W. R. Sins, Karin Fijnvandraat, Sietse Q. Nagelkerke, Judy Geissler, Michael W. Tanck, Christine Bruggeman, Bart J. Biemond, Anita W. Rijneveld, Jean-Louis H. Kerkhoffs, Sadaf Pakdaman, Anoosha Habibi, Robin van Bruggen, Taco W. Kuijpers, France Pirenne, Timo K. van den Berg

Blood (2017) 130 (19): 2121–2130.

https://doi.org/10.1182/blood-2017-05-784876

Published: 2017

Includes: Supplemental data

Journal Articles

RhIg-prophylaxis is not influenced by FCGR2/3 polymorphisms involved in red blood cell clearance

Tamara C. Stegmann, Barbera Veldhuisen, Sietse Q. Nagelkerke, Dian Winkelhorst, Henk Schonewille, Esther P. Verduin, Taco W. Kuijpers, Masja de Haas, Gestur Vidarsson, C. Ellen van der Schoot

Blood (2017) 129 (8): 1045–1048.

https://doi.org/10.1182/blood-2016-05-716365

Published: 2017

Includes: Supplemental data

Journal Articles

Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages

Sietse Q. Nagelkerke, Gillian Dekkers, Iwan Kustiawan, Fleur S. van de Bovenkamp, Judy Geissler, Rosina Plomp, Manfred Wuhrer, Gestur Vidarsson, Theo Rispens, Timo K. van den Berg, Taco W. Kuijpers

Blood (2014) 124 (25): 3709–3718.

https://doi.org/10.1182/blood-2014-05-576835

Published: 2014

Includes: Supplemental data

Journal Articles

RhD Immunization Despite Adequate Immunoprophylaxis: Role of Fc Gamma Receptor Gene Polymorphisms

Tamara C Stegmann, Sietse Q Nagelkerke, MD, Dian van Winkelhorst, MD, Taco W Kuijpers, MD PhD, Gestur Vidarsson, PhD, C. Ellen van der Schoot, MD PhD

Blood (2014) 124 (21): 759.

https://doi.org/10.1182/blood.V124.21.759.759

Published: 2014

Journal Articles

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

Roel P. Gazendam, John L. van Hamme, Anton T. J. Tool, Michel van Houdt, Paul J. J. H. Verkuijlen, Martin Herbst, Johannes G. Liese, Frank L. van de Veerdonk, Dirk Roos, Timo K. van den Berg, Taco W. Kuijpers

Blood (2014) 124 (4): 590–597.

https://doi.org/10.1182/blood-2014-01-551473

Published: 2014

Includes: Supplemental data

Journal Articles

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

Xi Wen Zhao, Roel P. Gazendam, Agata Drewniak, Michel van Houdt, Anton T. J. Tool, John L. van Hamme, Iwan Kustiawan, Alexander B. Meijer, Hans Janssen, David G. Russell, Lisette van de Corput, Kiki Tesselaar, Jaap J. Boelens, Ingrid Kuhnle, Jutte Van Der Werff Ten Bosch, Taco W. Kuijpers, Timo K. van den Berg

Blood (2013) 122 (1): 109–111.

https://doi.org/10.1182/blood-2013-03-494039

Published: 2013

Includes: Supplemental data

Journal Articles

Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency

Agata Drewniak, Roel P. Gazendam, Anton T. J. Tool, Michel van Houdt, Machiel H. Jansen, John L. van Hamme, Ester M. M. van Leeuwen, Dirk Roos, Emmanuel Scalais, Carine de Beaufort, Hans Janssen, Timo K. van den Berg, Taco W. Kuijpers

Blood (2013) 121 (13): 2385–2392.

https://doi.org/10.1182/blood-2012-08-450551

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

A novel flow cytometry–based platelet aggregation assay

Iris M. De Cuyper, Marjolein Meinders, Edith van de Vijver, Dirk de Korte, Leendert Porcelijn, Masja de Haas, Johannes A. Eble, Karl Seeger, Sergio Rutella, Daria Pagliara, Taco W. Kuijpers, Arthur J. Verhoeven, Timo K. van den Berg, Laura Gutiérrez

Blood (2013) 121 (10): e70–e80.

https://doi.org/10.1182/blood-2012-06-437723

Published: 2013

Includes: Supplemental data

Journal Articles

Memory CD4 + CCR5 + T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1

Madeleine J. Bunders, Chris M. van der Loos, Paul L. Klarenbeek, John L. van Hamme, Kees Boer, Jim C. H. Wilde, Niek de Vries, Rene A. W. van Lier, Neeltje Kootstra, Steven T. Pals, Taco W. Kuijpers

Blood (2012) 120 (22): 4383–4390.

https://doi.org/10.1182/blood-2012-06-437566

Published: 2012

Includes: Supplemental data

Journal Articles

Telomere Length and Telomerase Complex Mutations in Pediatric Acute Myeloid Leukemia

Anna M. Aalbers, Rodrigo T. Calado, Neal S. Young, Christian M. Zwaan, Colin O. Wu, Sachiko Kajigaya, PhD, Eva A. Coenen, André Baruchel, Karin Geleijns, Valerie de Haas, Gertjan J.L. Kaspers, MD, PhD, Taco W. Kuijpers, Dirk Reinhardt, MD, Jan Trka, MD, PhD, Martin Zimmermann, Rob Pieters, MD, PhD, Vincent H.J. van der Velden, Marry M. van den Heuvel-Eibrink

Blood (2012) 120 (21): 1482.

https://doi.org/10.1182/blood.V120.21.1482.1482

Published: 2012

Journal Articles

IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells

Jeroen den Dunnen, Lisa T. C. Vogelpoel, Tomasz Wypych, Femke J. M. Muller, Leonie de Boer, Taco W. Kuijpers, Sebastiaan A. J. Zaat, Martien L. Kapsenberg, Esther C. de Jong

Blood (2012) 120 (1): 112–121.

https://doi.org/10.1182/blood-2011-12-399931

Published: 2012

Includes: Supplemental data

NARROW

A phase 3 randomized trial of mavorixafor, a CXCR4 antagonist, for WHIM syndrome

Plasma Proteome Profiling of Sickle Cell Patients Reveals Activation of Inflammatory Pathways during Steady State and Vaso-Occlusive Crisis

IL-7 receptor signaling drives human B-cell progenitor differentiation and expansion

Pleiotropic Effects of Hydroxyurea on Red Blood Cell and Neutrophil Phenotype in Patients with Sickle Cell Disease; Data from the Notice Study

Formation of neutrophil extracellular traps requires actin cytoskeleton rearrangements

Global Phase 3, Randomized, Placebo-Controlled Trial with Open-Label Extension Evaluating the Oral CXCR4 Antagonist Mavorixafor in Patients with WHIM Syndrome (4WHIM): Trial Design and Enrollment

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis

Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease

RhIg-prophylaxis is not influenced by FCGR2/3 polymorphisms involved in red blood cell clearance

Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages

RhD Immunization Despite Adequate Immunoprophylaxis: Role of Fc Gamma Receptor Gene Polymorphisms

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency

A novel flow cytometry–based platelet aggregation assay

Memory CD4 + CCR5 + T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1

Telomere Length and Telomerase Complex Mutations in Pediatric Acute Myeloid Leukemia

IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells

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American Society of Hematology

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