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Tadashi Nagai
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Journal Articles

CD25 Expression Is Associated with Inferior Clinical Outcomes in Elderly Patients with Acute Myeloid Leukemia

Shin-ichiro Fujiwara, Kazuo Muroi, Raine Tatara, Kiyoshi Okazuka, Sato Kazuya, Iekuni Oh, Ken Ohmine, Takahiro Suzuki, Tadashi Nagai
Journal: Blood
Blood (2014) 124 (21): 3678.
https://doi.org/10.1182/blood.V124.21.3678.3678
Published: 2014
Journal Articles

Profiles Of De Novo CD25-Positive Mature B-Cell Lymphomas

Shin-ichiro Fujiwara, Raine Tatara, Kiyoshi Okazuka, Iekuni Oh, Ken Ohmine, Takahiro Suzuki, Masaki Mori, Tadashi Nagai, Keiya Ozawa, MD, PhD, Kazuo Muroi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4308.
https://doi.org/10.1182/blood.V122.21.4308.4308
Published: 2013
Journal Articles

Clinical Features of Newly Diagnosed CD25-Positive Follicular Lymphoma

Shin-ichiro Fujiwara, Kazuo Muroi, Raine Tatara, Ken Ohmine, Takahiro Suzuki, Masaki Mori, Tadashi Nagai, Akira Tanaka, Keiya Ozawa
Journal: Blood
Blood (2012) 120 (21): 1543.
https://doi.org/10.1182/blood.V120.21.1543.1543
Published: 2012
Journal Articles

Overcoming Resistance to 5-Azacytidine in Acute Myelogenous Leukemia

Piyanuch Sripayap, Tadashi Nagai, Mitsuyo Uesawa, Hiroyuki Kobayashi, Tomonori Tsukahara, Ken Ohmine, Kazuo Muroi, Gary Baley, Keiya Ozawa
Journal: Blood
Blood (2012) 120 (21): 1370.
https://doi.org/10.1182/blood.V120.21.1370.1370
Published: 2012
Journal Articles

Clinical Features of De Novo CD25-Positive Diffuse Large B-Cell Lymphoma

Shin-ichiro Fujiwara, Kazuo Muroi, Yuji Hirata, Kazuya Sato, Tomohiro Matsuyama, Ken Ohmine, Takahiro Suzuki, Katsutoshi Ozaki, Masaki Mori, M.D, Ph.D, Tadashi Nagai, MD, PhD, Keiya Ozawa, M.D, Ph.D
Journal: Blood
Blood (2011) 118 (21): 2666.
https://doi.org/10.1182/blood.V118.21.2666.2666
Published: 2011
Journal Articles

Stat3 Activation in Donor CD4 T-Cells Is Critical for Acute Gvhd

Katsutoshi Ozaki, Haruko Matsu, MD, PhD, Keiko Hatanaka, Akiko Meguro, MD, PhD, Iekuni Oh, MD, PhD, Raine Tatara, MD, PhD, Takahiro Suzuki, Masaki Mori, M.D, Ph.D, Tadashi Nagai, MD, PhD, Kazuo Muroi, MD, PhD, Keiya Ozawa, M.D, Ph.D
Journal: Blood
Blood (2011) 118 (21): 1906.
https://doi.org/10.1182/blood.V118.21.1906.1906
Published: 2011
Journal Articles

Phase I Study of Clofarabine (JC0707) in Adult Japanese Patients with Acute Myeloid Leukemia (AML)

Takahiro Yamauchi, MD, PhD, Tatsuya Suzuki, MD, PhD, Kiyoshi Ando, MD, PhD, Tadashi Nagai, MD, PhD, Kazuhiko Kakihana, MD, PhD, Yasuhiko Miyata, MD, PhD, Reginald Ewesuedo, MD, Yasuhiro Tabata, MD, PhD, Michinori Ogura
Journal: Blood
Blood (2011) 118 (21): 4295.
https://doi.org/10.1182/blood.V118.21.4295.4295
Published: 2011
Journal Articles

The Bone Marrow Hematopoietic Microenvironment Is Functionally Impaired in Iron-Overloaded Mice,

Hiroshi Okabe, Takahiro Suzuki, Eisuke Uehara, Masuzu Ueda, Tadashi Nagai, MD, PhD, Keiya Ozawa, M.D, Ph.D
Journal: Blood
Blood (2011) 118 (21): 3173.
https://doi.org/10.1182/blood.V118.21.3173.3173
Published: 2011
Journal Articles

Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study

Clinical Trials & Observations
Shigeki Ohtake, Shuichi Miyawaki, Hiroyuki Fujita, Hitoshi Kiyoi, Katsuji Shinagawa, Noriko Usui, Hirokazu Okumura, Koichi Miyamura, Chiaki Nakaseko, Yasushi Miyazaki, Atsushi Fujieda, Tadashi Nagai, Takahisa Yamane, Masafumi Taniwaki, Masatomo Takahashi, Fumiharu Yagasaki, Yukihiko Kimura, Norio Asou, Hisashi Sakamaki, Hiroshi Handa, Sumihisa Honda, Kazunori Ohnishi, Tomoki Naoe, Ryuzo Ohno
Journal: Blood
Blood (2011) 117 (8): 2358–2365.
https://doi.org/10.1182/blood-2010-03-273243
Published: 2011
Journal Articles

A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study

Clinical Trials & Observations
Shuichi Miyawaki, Shigeki Ohtake, Shin Fujisawa, Hitoshi Kiyoi, Katsuji Shinagawa, Noriko Usui, Toru Sakura, Koichi Miyamura, Chiaki Nakaseko, Yasushi Miyazaki, Atsushi Fujieda, Tadashi Nagai, Takahisa Yamane, Masafumi Taniwaki, Masatomo Takahashi, Fumiharu Yagasaki, Yukihiko Kimura, Norio Asou, Hisashi Sakamaki, Hiroshi Handa, Sumihisa Honda, Kazunori Ohnishi, Tomoki Naoe, Ryuzo Ohno
Journal: Blood
Blood (2011) 117 (8): 2366–2372.
https://doi.org/10.1182/blood-2010-07-295279
Published: 2011
Journal Articles

“Incidental Carcinomas” Detected by PET/CT Scans In the Patients with Malignant Lymphoma: A Single-Center Experience with 363 Patients

Kazuya Sato, MD, PhD, Katsutoshi Ozaki, MD, PhD, Tomohiro Matsuyama, MD, Ken Ohmine, MD, PhD, Takahiro Suzuki, MD, PhD, Masaki Mori, MD, PhD, Tadashi Nagai, MD, PhD, Kazuo Muroi, MD, PhD, Keiya Ozawa, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4132.
https://doi.org/10.1182/blood.V116.21.4132.4132
Published: 2010
Journal Articles

Sustained Superior Long-Term Outcomes of Imatinib Therapy In Japanese Patients with Newly Diagnosed Chronic Myelogenous Leukemia In Chronic Phase: Sub-Analysis According to the Mean Daily Dose of Imatinib and the Plasma Trough Levels In JALSG CML202 Study After 66 Months Follow-up.

Chiaki Nakaseko, MD, Kazunori Ohnishi, MD, Jin Takeuchi, MD, Shin Fujisawa, MD, Tadashi Nagai, MD, Shigeki Ohtake, MD, PhD, Hirohito Yamazaki, MD, Tetsuzo Tauchi, MD, Kiyotoshi Imai, Naoki Mori, MD, Fumiharu Yagasaki, MD, Hideki Akiyama, MD, Yasuhiro Maeda, MD, Noriko Usui, MD, Yoshio Saburi, MD, Takashi Ishida, MD, Hiroshi Kosugi, MD, Koichi Miyamura, MD, Yasushi Miyazaki, MD, Hiroshi Handa, MD, Akira Yokota, MD, Kenji Matsumoto, MD, Katsumichi Fujimaki, MD, Toshimitsu Matsui, MD, Hitoshi Kiyoi, MD, Shuichi Miyawaki, MD, Ryuzo Ohno, MD, Tomoki Naoe, MD
Journal: Blood
Blood (2010) 116 (21): 3417.
https://doi.org/10.1182/blood.V116.21.3417.3417
Published: 2010
Journal Articles

Ectopic Expression and Role of RCAN1 in Myeloid Leukemia Cells.

Shin-ichiro Fujiwara, Tadashi Nagai, Satoru Kikuchi, Mitsuyo Uesawa, Chihiro Sakurai, Ken Ohmine, Jiro Kikuchi, Yusuke Furukawa, Keiya Ozawa
Journal: Blood
Blood (2009) 114 (22): 1274.
https://doi.org/10.1182/blood.V114.22.1274.1274
Published: 2009
Journal Articles

C-Cbl Regulates Interaction of Immature Hematopoietic Cells with the Bone Marrow Microenvironment by Rac GTPase-Mediated Cytoskeletal Signals.

Eisuke Uehara, Takahiro Suzuki, Hiroshi Okabe, Masuzu Ueda, Tadashi Nagai, Masashi Sanada, Seishi Ogawa, Keiya Ozawa
Journal: Blood
Blood (2009) 114 (22): 3643.
https://doi.org/10.1182/blood.V114.22.3643.3643
Published: 2009
Journal Articles

Mesenchymal Stem Cells Inhibit Th17 Differentiation through PGE2 Production.

Raine Tatara, Katsutoshi Ozaki, Lekuni Oh, Keiko Hatanaka, Akiko Meguro, Haruko Matsu, Kazuya Sato, Tadashi Nagai, Kazuo Muroi, Keiya Ozawa
Journal: Blood
Blood (2009) 114 (22): 3633.
https://doi.org/10.1182/blood.V114.22.3633.3633
Published: 2009
Journal Articles

Vincristine Potentiates the Anti-Leukemia Effect of the Aurora Kinase Inhibitor VE-465 by Enhancing Apoptosis in Myeloid Leukemia Cells.

Ken Ohmine, MD, PhD, Tadashi Nagai, MD, PhD, Kozue Yoshida, MD, PhD, Shin-ichiro Fujiwara, MD, PhD, Mitsuyo Uesawa, MD, Chihiro Sakurai, MD, Keiya Ozawa, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2762.
https://doi.org/10.1182/blood.V114.22.2762.2762
Published: 2009
Journal Articles

Long-Term Follow-up of the Randomized JALSG AML 201 Study Comparing High Dose Ara-C Therapy with Conventional Consolidation Therapy in Adult Acute Myeloid Leukemia (AML)

Shuichi Miyawaki, Shigeki Ohtake, Shin Fujisawa, Hitoshi Kiyoi, Katsuji Shinagawa, Noriko Usui, Kohichi Miyamura, MD, Miki Nishimura, MD, Yasushi Miyazaki, Kazuhiro Nishii, Tadashi Nagai, Takahisa Yamane, MD, Masafumi Taniwaki, Masatomo Takahashi, MD, Fumiharu Yagasaki, Yukihiko Kimura, Norio Asou, Sumihisa Honda, Kazunori Ohnishi, Tomoki Naoe, Ryuzo Ohno
Journal: Blood
Blood (2008) 112 (11): 135.
https://doi.org/10.1182/blood.V112.11.135.135
Published: 2008
Journal Articles

Updated Results of JALSG AML201 Study Comparing Intensified Daunorubicin with Idarubicin in Patients with De Novo Acute Myeloid Leukemia: Effect of Hematopoietic Stem Cell Transplantation.

Shigeki Ohtake, MD, Shuichi Miyawaki, MD, Hiroyuki Fujita, MD, Hitoshi Kiyoi, MD, Katsuji Shinagawa, MD, Noriko Usui, MD, Kohichi Miyamura, MD, Miki Nishimura, MD, Yasushi Miyazaki, MD, Kazuhiro Nishii, MD, Tadashi Nagai, MD, Takahisa Yamane, MD, Masafumi Taniwaki, MD, Masatomo Takahashi, MD, Fumiharu Yagasaki, MD, Yukihiko Kimura, MD, Norio Asou, MD, Sumihisa Honda, Ph.D., Kazunori Ohnishi, MD, Tomoki Naoe, MD, Ryuzo Ohno, MD
Journal: Blood
Blood (2008) 112 (11): 2171.
https://doi.org/10.1182/blood.V112.11.2171.2171
Published: 2008
Journal Articles

Bortezomib Overcomes Cell Adhesion-Mediated Drug Resistance Via Down-Regulation of VLA-4 Expression in Multiple Myeloma.

Kaoru Hatano, Jiro Kikuchi, Masaaki Takatoku, Rumi Shimizu, Taeko Wada, Masuzu Ueda, Masaharu Nobuyoshi, Iekuni Oh, Kazuya Sato, Takahiro Suzuki, Katsutoshi Ozaki, Masaki Mori, Tadashi Nagai, Kazuo Muroi, Yasuhiko Kano, Yusuke Furukawa, Keiya Ozawa
Journal: Blood
Blood (2008) 112 (11): 1634.
https://doi.org/10.1182/blood.V112.11.1634.1634
Published: 2008
Journal Articles

Lower Dose of Imatinib Provides Outcomes Similar to the Standard Dose Imatinib in Japanese Patients with Early Chronic-Phase CML: The Interim Analyses of JALSG CML202 Study.

Kazunori Ohnishi, Miki Nishimura, Jin Takeuchi, Shin Fujisawa, Tadashi Nagai, Koichi Miyamura, Yukihiko Kimura, Fumiharu Yagasaki, Hideki Akiyama, Noriko Usui, Shigeki Ohtake, on behalf of JALSG
Journal: Blood
Blood (2007) 110 (11): 1044.
https://doi.org/10.1182/blood.V110.11.1044.1044
Published: 2007