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Journal Articles

Loss of Zyx Impairs Neutrophil Production in Zebrafish Embryos

Katsuhiro Konno, Kasem Kulkeaw, Takenobu Nii, PhD, Ayako Kaneyuki, Daisuke Sugiyama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5001.
https://doi.org/10.1182/blood-2019-126644
Published: 2019
Journal Articles

Dual Targeting of Mitochondrial Unfolded Protein Response and BCL2 in Acute Myeloid Leukemia

Ran Zhao, BS, Sarah Zarabi, MD, Takenobu Nii, PhD, Ondrej Halgas, PhD, Yulia Jitkova, PhD, Vivian Ruvolo, Lauren Heese, Yuki Nishida, MD PhD, Gautam M. Borthakur, MD, Kensuke Kojima, MD PhD, Martin Stogniew, Wolfgang Oster, MD, Emil Pai, PhD, Eric Davis, MD, Hagop M. Kantarjian, MD, Aaron D Schimmer, MD PhD, Michael Andreeff, MD PhD, Jo Ishizawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2562.
https://doi.org/10.1182/blood-2019-127101
Published: 2019
Journal Articles

The Novel Imipridone ONC212 Induces Pronounced Anti-Leukemia Effects in Vitro and In Vivo and Is Highly Synergistic with the BCL-2 Inhibitor ABT-199

Takenobu Nii, PhD, Jo Ishizawa, MD PhD, Varun Vijay Prabhu, BPharm, MS, PhD, Vivian Ruvolo, PhD, Neel Madhukar, Ran Zhao, Hong Mu, MD PhD, Lauren Heese, Kensuke Kojima, MD PhD, Mathew Garnett, Ultan McDermott, Cyril H Benes, Neil Charter, Sean Deacon, Olivier Elemento, PhD, Joshua E. Allen, PhD, Wolfgang Oster, MD, Martin Stogniew, Michael Andreeff, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2616.
https://doi.org/10.1182/blood.V130.Suppl_1.2616.2616
Published: 2017
Journal Articles

ONC212 Is a Potent Member of the Imipridone Class of Anti-Cancer Compounds That Induces p53-Independent Apoptosis in Hematological Malignancies

Takenobu Nii, PhD, Jo Ishizawa, MD PhD, Ran Zhao, Jianfang Zeng, MD PhD, Dhruv Chachad, Kensuke Kojima, MD PhD, Marina Konopleva, MD PhD, Richard Eric Davis, MD, Joshua E Allen, PhD, Martin Stogniew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4059.
https://doi.org/10.1182/blood.V128.22.4059.4059
Published: 2016
Journal Articles

Single-Cell-State Culture of Human Pluripotent Stem Cells Increases Transfection Efficiency

Takenobu Nii, PhD, Hiroshi Kohara, PhD, Tomotoshi Marumoto, MD PhD, Tetsushi Sakuma, PhD, Takashi Yamamoto, PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2037.
https://doi.org/10.1182/blood.V126.23.2037.2037
Published: 2015
Journal Articles

Newly Developed Measles Viral Vector Can Efficiently Transduce Multiple Genes into naïve T Cells

Takafumi Hiramoto, PhD, Maino Tahara, PhD, Yoshie Miura, PhD, Yuichiro Nakatsu, PhD, Toru Kubota, MD PhD, Ryo Kurita, PhD, Hiroshi Hamana, PhD, Chika Sakamoto, Megumi Narusawa, PhD, Saori Yamaguchi, Hiroaki Ono, MD, Jiuan Liao, PhD, Takenobu Nii, PhD, Yuto Takishima, Michiyo Okada, Yumiko Matsumura, DVM PhD, Yoshihiro Tanaka, PhD, Kazunari Yamada, MD, PhD, Yasuki Hijikata, MD PhD, Hiroshi Kohara, PhD, Sonoko Ishihara, MD PhD, Toshihisa Tsuruta, MD PhD, Toshihiko Okazaki, MD PhD, Hiroyuki Kishi, MD PhD, Atsushi Muraguchi, MD PhD, Akihide Ryo, MD PhD, Makoto Takeda, MD PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4798.
https://doi.org/10.1182/blood.V124.21.4798.4798
Published: 2014
Journal Articles

Improved Hematopoietic Differentiation of Primate Embryonic Stem Cells

Takenobu Nii, PhD, Tomotoshi Marumoto, MD PhD, Saori Yamaguchi, Hirotaka Kawano, Yoshie Kametani, PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2918.
https://doi.org/10.1182/blood.V124.21.2918.2918
Published: 2014
Journal Articles

Induced Hematopoietic Differentiation Of Common Marmoset Embryonic Stem Cells By LYL1 Can Give Rise To Hematopoietic Stem Cells Having The Enhanced Bone Marrow Reconstitution Capability

Hirotaka Kawano, Tomotoshi Marumoto, MD, PhD, Takafumi Hiramoto, PhD, Michiyo Okada, Tomoko Inoue, PhD, Takenobu Nii, Jiyuan Liao, Saori Yamaguchi, Hiroyuki Inoue, MD, PhD, Erika Sasaki, PhD, Yoshie Miura, PhD, Kenzaburo Tani, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1192.
https://doi.org/10.1182/blood.V122.21.1192.1192
Published: 2013
Journal Articles

Efficient Hematopoietic Differentiation of Common Marmoset Embryonic Stem Cells by the Inhibition of Their Self-Renewal Pathway.

Takenobu Nii, Tomotoshi Marumoto, MD, PhD, Hirotaka Kawano, Saori Yamaguchi, Yoko Nagai, Jiyuan Liao, Michiyo Okada, Yoshie Miura, PhD, Kenzaburo Tani, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2311.
https://doi.org/10.1182/blood.V120.21.2311.2311
Published: 2012
Journal Articles

Efficient Differentiation of Common Marmoset Embryonic Stem Cells Into Hemangioblast-Like Cells by the Inhibition of PI3K-AKT Pathway

Takenobu Nii, Tomotoshi Marumoto, MD, PhD, Hirotaka Kawano, Saori Yamaguchi, Yoko Nagai, Yoshie Miura, PhD, Jiyuan Liao, Michiyo Okada, Kenzaburo Tani, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2206.
https://doi.org/10.1182/blood.V118.21.2206.2206
Published: 2011
Journal Articles

LYL1, Class II Basic Helix-Loop-Helix Transcription Factor, Induces the Differentiation of Common Marmoset Embryonic Stem Cells to Hematopoietic Stem Cells

Hirotaka Kawano, Tomotoshi Marumoto, MD, PhD, Michiyo Okada, Tomoko Inoue, PhD, Takenobu Nii, Jiyuan Liao, Saori Yamaguchi, Yoko Nagai, Hiroyuki Inoue, MD, PhD, Erika Sasaki, PhD, Yoshie Miura, PhD, Kenzaburo Tani, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2348.
https://doi.org/10.1182/blood.V118.21.2348.2348
Published: 2011
Journal Articles

Inhibition of PTEN Tumor Suppressor Promotes the Generation of Induced Pluripotent Stem Cells

Jiyuan Liao, Tomotoshi Marumoto, MD, PhD, Shinji Okano, Saori Yamaguchi, Takenobu Nii, Hirotaka Kawano, Yoko Nagai, Chika Sakamoto, Michiyo Okada, Yoshie Miura, PhD, Hiroyuki Inoue, MD, PhD, Masato Tanaka, Kaori Nagatoshi, Kohichi Kawahara, PhD, Akira Suzuki, MD, PhD, Kenzaburo Tani, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3122.
https://doi.org/10.1182/blood.V118.21.3122.3122
Published: 2011