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Journal Articles

Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies

Blood (2021) 137 (3): 349–363.

https://doi.org/10.1182/blood.2020007292

Published: 2021

Includes: Supplemental data

Journal Articles

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery

Elie Haddad, Brent R. Logan, Linda M. Griffith, Rebecca H. Buckley, Roberta E. Parrott, Susan E. Prockop, Trudy N. Small, Jessica Chaisson, Christopher C. Dvorak, Megan Murnane, Neena Kapoor, Hisham Abdel-Azim, Imelda C. Hanson, Caridad Martinez, Jack J. H. Bleesing, Sharat Chandra, Angela R. Smith, Matthew E. Cavanaugh, Soma Jyonouchi, Kathleen E. Sullivan, Lauri Burroughs, Suzanne Skoda-Smith, Ann E. Haight, Audrey G. Tumlin, Troy C. Quigg, Candace Taylor, Blachy J. Dávila Saldaña, Michael D. Keller, Christine M. Seroogy, Kenneth B. Desantes, Aleksandra Petrovic, Jennifer W. Leiding, David C. Shyr, Hélène Decaluwe, Pierre Teira, Alfred P. Gillio, Alan P. Knutsen, Theodore B. Moore, Morris Kletzel, John A. Craddock, Victor Aquino, Jeffrey H. Davis, Lolie C. Yu, Geoffrey D. E. Cuvelier, Jeffrey J. Bednarski, Frederick D. Goldman, Elizabeth M. Kang, Evan Shereck, Matthew H. Porteus, James A. Connelly, Thomas A. Fleisher, Harry L. Malech, William T. Shearer, Paul Szabolcs, Monica S. Thakar, Mark T. Vander Lugt, Jennifer Heimall, Ziyan Yin, Michael A. Pulsipher, Sung-Yun Pai, Donald B. Kohn, Jennifer M. Puck, Morton J. Cowan, Richard J. O'Reilly, Luigi D. Notarangelo

Blood (2018) 132 (17): 1737–1749.

https://doi.org/10.1182/blood-2018-03-840702

Published: 2018

Includes: Supplemental data

Journal Articles

Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype

Hye Sun Kuehn, Julie E. Niemela, Karthik Sreedhara, Jennifer L. Stoddard, Jennifer Grossman, Christian A. Wysocki, M. Teresa de la Morena, Mary Garofalo, Jingga Inlora, Michael P. Snyder, David B. Lewis, Constantine A. Stratakis, Thomas A. Fleisher, Sergio D. Rosenzweig

Blood (2017) 130 (13): 1553–1564.

https://doi.org/10.1182/blood-2017-05-782177

Published: 2017

Includes: Supplemental data

Journal Articles

JMML and RALD (Ras-associated autoimmune leukoproliferative disorder): common genetic etiology yet clinically distinct entities

Katherine R. Calvo, Susan Price, Raul C. Braylan, Joao Bosco Oliveira, Michael Lenardo, Thomas A. Fleisher, V. Koneti Rao

Blood (2015) 125 (18): 2753–2758.

https://doi.org/10.1182/blood-2014-11-567917

Published: 2015

Includes: Supplemental data

Journal Articles

Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell–depleted stem cell transplantation

Nirali N. Shah, Kristin Baird, Cynthia P. Delbrook, Thomas A. Fleisher, Mark E. Kohler, Shakuntala Rampertaap, Kimberly Lemberg, Carolyn K. Hurley, David E. Kleiner, Melinda S. Merchant, Stefania Pittaluga, Marianna Sabatino, David F. Stroncek, Alan S. Wayne, Hua Zhang, Terry J. Fry, Crystal L. Mackall

Blood (2015) 125 (5): 784–792.

https://doi.org/10.1182/blood-2014-07-592881

Published: 2015

Journal Articles

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor

Blood (2014) 123 (15): 2308–2316.

https://doi.org/10.1182/blood-2013-09-527226

Published: 2014

Includes: Supplemental data

Journal Articles

Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations

Susan Price, Pamela A. Shaw, Amy Seitz, Gyan Joshi, Joie Davis, Julie E. Niemela, Katie Perkins, Ronald L. Hornung, Les Folio, Philip S. Rosenberg, Jennifer M. Puck, Amy P. Hsu, Bernice Lo, Stefania Pittaluga, Elaine S. Jaffe, Thomas A. Fleisher, V. Koneti Rao, Michael J. Lenardo

Blood (2014) 123 (13): 1989–1999.

https://doi.org/10.1182/blood-2013-10-535393

Published: 2014

Includes: Supplemental data

Journal Articles

Study On The Fertility Status Of Females With Primary Mediastinal B-Cell Lymphoma Following Treatment With Dose-Adjusted EPOCH-Rituximab

Helen Gharwan, MD, DSc, Kieron Dunleavy, MD, Margaret Shovlin, RN, Antonio T Fojo, MD, PhD, Thomas A. Fleisher, MD, Wyndham H Wilson, MD, PhD, Cliona Grant, MD

Blood (2013) 122 (21): 1779.

https://doi.org/10.1182/blood.V122.21.1779.1779

Published: 2013

Journal Articles

Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans

Hye Sun Kuehn, Julie E. Niemela, Andreia Rangel-Santos, Mingchang Zhang, Stefania Pittaluga, Jennifer L. Stoddard, Ashleigh A. Hussey, Moses O. Evbuomwan, Debra A. Long Priel, Douglas B. Kuhns, C. Lucy Park, Thomas A. Fleisher, Gulbu Uzel, João B. Oliveira

Blood (2013) 121 (16): 3117–3125.

https://doi.org/10.1182/blood-2012-12-469544

Published: 2013

Includes: Supplemental data

Journal Articles

Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia

Thomas A. Waldmann, Kevin C. Conlon, Donn M. Stewart, TatYana A. Worthy, John E. Janik, Thomas A. Fleisher, Paul S. Albert, William D. Figg, Shawn D. Spencer, Mark Raffeld, Jean R. Decker, Carolyn K. Goldman, Bonita R. Bryant, Michael N. Petrus, Stephen P. Creekmore, John C. Morris

Blood (2013) 121 (3): 476–484.

https://doi.org/10.1182/blood-2012-08-450585

Published: 2013

Includes: Supplemental data

Journal Articles

Clinical Spectrum of RAS-Associated Autoimmune Leukoproliferative Disorder (RALD): A Distinct Clinical Entity Mimicking Juvenile Myelomonocytioc Leukemia (JMML) or Chronic Myelomonocytic Leukemia (CMML)

V. Koneti Rao, Joao Bosco Oliveira, MD, PhD, Julie Niemela, PhD, Joie Davis, NP, Susan Price, Hyesun Kuehn, Katherine R Calvo, MD, PhD, Stefania Pittaluga, Eric J. Werner, MD, Joohee Lee, MD, Mustafa Barbour, MD, Marc Natter, MD, Mignon L. Loh, MD, Thomas A Fleisher

Blood (2012) 120 (21): 1033.

https://doi.org/10.1182/blood.V120.21.1033.1033

Published: 2012

Journal Articles

Expanding Spectrum of Malignancies in ALPS: A Cancer Predisposing Syndrome?.

Katie Perkins, NP, Joie Davis, NP, Susan Price, RN, Julie Niemela, PhD, Andreas R. Huber, MD, Donna A. Wall, MD, Stefania Pittaluga, MD, PhD, Thomas A. Fleisher, MD, V. Koneti Rao, MD

Blood (2012) 120 (21): 2149.

https://doi.org/10.1182/blood.V120.21.2149.2149

Published: 2012

Journal Articles

The BH3 Mimetic, Small Molecule, ABT-737, Was Effective As Lympholytic Therapy in the MRL/lpr −/− Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS)

Kennichi C. Dowdell, PhD, Lu Lianghao, MD, PhD, V. Koneti Rao, Thomas A. Fleisher, MD, Joao Bosco Oliveira, MD, PhD

Blood (2011) 118 (21): 695.

https://doi.org/10.1182/blood.V118.21.695.695

Published: 2011

Journal Articles

Yttrium-90 Radiolabeled Daclizumab, An Anti-CD25 Monoclonal Antibody, Provides Effective Therapy for Refractory and Relapsed Hodgkin's Lymphoma,

Blood (2011) 118 (21): 3706.

https://doi.org/10.1182/blood.V118.21.3706.3706

Published: 2011

Journal Articles

The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome

David H. McDermott, Qian Liu, Jean Ulrick, Nana Kwatemaa, Sandra Anaya-O'Brien, Scott R. Penzak, Joao Oliveira Filho, Debra A. Long Priel, Corin Kelly, Mary Garofalo, Patricia Littel, Martha M. Marquesen, Diane Hilligoss, Rosamma DeCastro, Thomas A. Fleisher, Douglas B. Kuhns, Harry L. Malech, Philip M. Murphy

Blood (2011) 118 (18): 4957–4962.

https://doi.org/10.1182/blood-2011-07-368084

Published: 2011

Includes: Supplemental data

Journal Articles

Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand

Ashish Jain, Joseph A. Kovacs, David L. Nelson, Stephen A. Migueles, Stefania Pittaluga, William Fanslow, Xiying Fan, Duane W. Wong, Justin Massey, Ronald Hornung, Margaret R. Brown, Jacob J. Spinner, Shuying Liu, Victoria Davey, Harry A. Hill, Hans Ochs, Thomas A. Fleisher

Blood (2011) 118 (14): 3811–3817.

https://doi.org/10.1182/blood-2011-04-351254

Published: 2011

Includes: Supplemental data

Journal Articles

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

Thomas A. Waldmann, Enrico Lugli, Mario Roederer, Liyanage P. Perera, Jeremy V. Smedley, Rhonda P. Macallister, Carolyn K. Goldman, Bonita R. Bryant, Jean M. Decker, Thomas A. Fleisher, H. Clifford Lane, Michael C. Sneller, Roger J. Kurlander, David E. Kleiner, John M. Pletcher, William D. Figg, Jason L. Yovandich, Stephen P. Creekmore

Blood (2011) 117 (18): 4787–4795.

https://doi.org/10.1182/blood-2010-10-311456

Published: 2011

Includes: Supplemental data

Journal Articles

Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis

Julie E. Niemela, Lianghao Lu, Thomas A. Fleisher, Joie Davis, Iusta Caminha, Marc Natter, Laurel A. Beer, Kennichi C. Dowdell, Stefania Pittaluga, Mark Raffeld, V. Koneti Rao, João B. Oliveira

Blood (2011) 117 (10): 2883–2886.

https://doi.org/10.1182/blood-2010-07-295501

Published: 2011

Includes: Supplemental data

Journal Articles

Rituximab Is Associated with Prolonged Immunoglobulin Deficiency In Newly Diagnosed Patients with Aggressive B-Cell Lymphoma Receiving Immunochemotherapy

Kieron Dunleavy, MD, Benjamin L.W. Reiter, Cliona M. Grant, MD, Margaret Shovlin, RN, George W. Wright, Thomas A. Fleisher, MD, Wyndham H. Wilson, MD, PhD

Blood (2010) 116 (21): 2881.

https://doi.org/10.1182/blood.V116.21.2881.2881

Published: 2010

Journal Articles

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop

Joao B. Oliveira, Jack J. Bleesing, Umberto Dianzani, Thomas A. Fleisher, Elaine S. Jaffe, Michael J. Lenardo, Frederic Rieux-Laucat, Richard M. Siegel, Helen C. Su, David T. Teachey, V. Koneti Rao

Blood (2010) 116 (14): e35–e40.

https://doi.org/10.1182/blood-2010-04-280347

Published: 2010

Includes: Supplemental data

NARROW

Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery

Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype

JMML and RALD (Ras-associated autoimmune leukoproliferative disorder): common genetic etiology yet clinically distinct entities

Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell–depleted stem cell transplantation

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor

Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations

Study On The Fertility Status Of Females With Primary Mediastinal B-Cell Lymphoma Following Treatment With Dose-Adjusted EPOCH-Rituximab

Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans

Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia

Clinical Spectrum of RAS-Associated Autoimmune Leukoproliferative Disorder (RALD): A Distinct Clinical Entity Mimicking Juvenile Myelomonocytioc Leukemia (JMML) or Chronic Myelomonocytic Leukemia (CMML)

Expanding Spectrum of Malignancies in ALPS: A Cancer Predisposing Syndrome?.

The BH3 Mimetic, Small Molecule, ABT-737, Was Effective As Lympholytic Therapy in the MRL/lpr −/− Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS)

Yttrium-90 Radiolabeled Daclizumab, An Anti-CD25 Monoclonal Antibody, Provides Effective Therapy for Refractory and Relapsed Hodgkin's Lymphoma,

The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome

Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis

Rituximab Is Associated with Prolonged Immunoglobulin Deficiency In Newly Diagnosed Patients with Aggressive B-Cell Lymphoma Receiving Immunochemotherapy

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop

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American Society of Hematology

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American Society of Hematology

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