1-8 of 8
Tim CP Somervaille
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

MSC Reprogramming and Aberrant Inflammatory Signaling in Myelofibrosis: Insights from Single-Cell RNA-Sequencing of Trephine Bone Marrow Cells

Naseer J Basma, Alexia J Strickson, Kristian Gurashi, Maria Kleppe, Hugh Young Rienhoff Jr., Jr., Tim CP Somervaille
Journal: Blood
Blood (2023) 142 (Supplement 1): 743.
https://doi.org/10.1182/blood-2023-181674
Published: 2023
Journal Articles

Transform-1: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, International Phase 3 Study of Navitoclax in Combination with Ruxolitinib Versus Ruxolitinib Plus Placebo in Patients with Untreated Myelofibrosis

Naveen Pemmaraju, Adam J Mead, Tim CP Somervaille, James K McCloskey, Francesca Palandri, Steffen Koschmieder, David Lavie, Brian Leber, Su-Peng Yeh, Maria Teresa Gómez-Casares, Emanuele Ammatuna, Ho-Jin Shin, Keita Kirito, Eric Jourdan, Timothy Devos, Hun S Chuah, Atanas Radinoff, Andrija Bogdanovic, Rastislav Moskal, Qi Jiang, Avijeet S Chopra, Elektra Papadopoulos, Jalaja Potluri, Francesco Passamonti
Journal: Blood
Blood (2023) 142 (Supplement 1): 620.
https://doi.org/10.1182/blood-2023-173509
Published: 2023
Journal Articles

NK-2 Homeobox Transcription Factor NKX2-3 Confers Differentiation Block in NPM1-Mutated in Acute Myeloid Leukaemia

John A Chadwick, Bettina Wingelhofer, Tim CP Somervaille
Journal: Blood
Blood (2023) 142 (Supplement 1): 2759.
https://doi.org/10.1182/blood-2023-182990
Published: 2023
Journal Articles

Results from a Phase 2 Study of Navitoclax in Combination with Ruxolitinib in Patients with Primary or Secondary Myelofibrosis

Claire N Harrison, Professor, Jacqueline S Garcia, MD, Ruben A Mesa, MD, Tim CP Somervaille, MD PhD, Rami S. Komrokji, MD, Naveen Pemmaraju, MD, Catriona Jamieson, MD PhD, Nikolaos Papadantonakis, MDPhDMSc, James M. Foran, MD, Casey L. O'Connell, MD, Leanne Holes, BS, MBA,, Jia Jia, PhD MBA, Jason Harb, PhD, Jessica Hutti, PhD, Josef T. Prchal, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 671.
https://doi.org/10.1182/blood-2019-130158
Published: 2019
Journal Articles

Iadademstat Shows Efficacy in Elderly AML Patients in Combination with Azacitidine. Alice Trial

Carlos Buesa, PhD, Tim CP Somervaille, MD PhD, Mabel Arevalo, PhD, Jordi Xaus, PhD, Sonia Gutierrez, Roger Bullock, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3839.
https://doi.org/10.1182/blood-2019-125121
Published: 2019
Journal Articles

An Open-Label Phase I/IIa Study to Evaluate the Safety and Efficacy of CCS1477, a First in Clinic Inhibitor of the p300/CPB Bromodomains, As Monotherapy in Patients with Advanced Haematological Malignancies

Tomasz Knurowski, PhD MD, Karen Clegg, PhD, Nigel Brooks, PhD, Fay Ashby, Neil A Pegg, PhD, William West, PhD, Harriet S Walter, Tim CP Somervaille, MD PhD, Steven Knapper, DM, Andrew Davies, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1266.
https://doi.org/10.1182/blood-2019-124797
Published: 2019
Journal Articles

CCS1477: A Novel Small Molecule Inhibitor of p300/CBP Bromodomain for the Treatment of Acute Myeloid Leukaemia and Multiple Myeloma

Nigel Brooks, PhD, Meera Raja, PhD, Barbara W Young, PhD, Gary J Spencer, PhD, Tim CP Somervaille, MD PhD, Neil A Pegg, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2560.
https://doi.org/10.1182/blood-2019-124707
Published: 2019
Journal Articles

Genome-Wide CRISPR-Cas9 Screen Identifies Sensitizers to LSD1 Inhibition in MLL-Translocated Human AML Cells

Gauri Deb, MS, PhD, Bettina Wingelhofer, PhD, Emma Williams, PhD, Hui-Sun Leong, PhD, Tim CP Somervaille, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 178.
https://doi.org/10.1182/blood-2018-178
Published: 2018