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Journal Articles

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Atanas Kamburow, PhD, Robert A. Redd, MS, Michael Lawrence, PhD, Margaretha G.M. Roemer, MSc, Amy Li, Marita Ziepert, PhD, Annette M. Staiger, PhD, Jeremiah Wala, Matthew D. Ducar, MS, Ignaty Leshchiner, PhD, Esther Rheinbay, PhD, Amaro Taylor-Weiner, BS, Caroline Coughlin, BS, Julian Hess, Chandra Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, MD, Brian K Link, MD, Anne J Novak, PhD, James R. Cerhan, MD PhD, Thomas M Habermann, MD, Reiner Siebert, PhD, Andreas Rosenwald, Aaron R. Thorner, PhD, Matthew Meyerson, MDPhD, Todd R. Golub, MD, Rameen Beroukhim, Gerald Wulf, MD, German Ott, MD, Scott J. Rodig, MDPhD, Stefano Monti, PhD, Donna S. Neuberg, ScD, Markus Loeffler, MD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD

Blood (2017) 130 (Supplement 1): 38.

https://doi.org/10.1182/blood.V130.Suppl_1.38.38

Published: 2017

Journal Articles

Identification and Validation of Molecular Markers of Tumor Cell Resistance to Natural Killer Cells through CRISPR-Based Screens and Large-Scale Phenotypic Screens of Pooled Tumor Cell Lines

Michal Sheffer, PhD, Lotte Wieten, PhD, Channing Yu, MD PhD, Yiguo Yu, PhD, Olga Dashevsky, PhD, Emily Lowry, Jennifer Roth, Aviad Tsherniak, PhD, Chris C Mader, Sam Bender, Jordan Bryan, Cong Zhu, Li Wang, Ricardo De Matos Simoes, PhD, Sara Gandolfi, MD, Eugen Dhimolea, PhD, Megan Bariteau, Todd R. Golub, MD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 623.

https://doi.org/10.1182/blood.V130.Suppl_1.623.623

Published: 2017

Journal Articles

Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution

Jens G Lohr, MD PhD, Sora Kim, Joshua Gould, Birgit Knoechel, MD PhD, Yotam Drier, PhD, Daniel Gray, PhD, Nicole Birrer, Bang Wong, Gavin Ha, PhD, Cheng-Zhong Zhang, PhD, Guangwu Guo, Matthew Meyerson, MD PhD, Andrew Yee, Jesse Boehm, PhD, Noopur Raje, MD, Todd R. Golub, MD

Blood (2016) 128 (22): 800.

https://doi.org/10.1182/blood.V128.22.800.800

Published: 2016

Journal Articles

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

Blood (2015) 126 (23): 3922.

https://doi.org/10.1182/blood.V126.23.3922.3922

Published: 2015

Journal Articles

The Somatic Cancer Genome

Todd R. Golub, MD

Blood (2014) 124 (21): SCI-4.

https://doi.org/10.1182/blood.V124.21.SCI-4.SCI-4

Published: 2014

Journal Articles

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Blood (2014) 124 (21): 74.

https://doi.org/10.1182/blood.V124.21.74.74

Published: 2014

Journal Articles

Ex Vivo expansion Of Umbilical Cord Blood CD34+ Cells Under Hypoxic Conditions Using Novel Compound#999 With Cytokines

Saadiya Khan, MD, Alison L. Stewart, PhD, Siddhartha Mukherjee, MD, PhD, Stuart L. Scheiber, Benjamin L. Ebert, MD, DPhil, Todd R. Golub, MD, David T. Scadden, M.D., Malcolm A.S. Moore, D.Phil

Blood (2013) 122 (21): 4508.

https://doi.org/10.1182/blood.V122.21.4508.4508

Published: 2013

Journal Articles

A Structural Basis for p53-Deficiency, Deregulated Cell Cycle and Unfavorable Outcome in Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MD, PhD, Stefano Monti, PhD, Kunihiko Takeyama, MD, PhD, Scott J Rodig, MD, PhD, Yansheng Hao, MD, PhD, Kelly T Yeda, Haig Inguilizian, MD, Craig Mermel, Treeve Currie, Ahmet Dogan, MD, PhD, Jeffery Kutok, MD, PhD, Rameen Beroukhim, MD, PhD, Donna S. Neuberg, ScD, Thomas M Habermann, MD, Gad Getz, PhD, Andrew L. Kung, MD, PhD, Todd R. Golub, MD, Margaret A. Shipp, MD

Blood (2012) 120 (21): 1534.

https://doi.org/10.1182/blood.V120.21.1534.1534

Published: 2012

Journal Articles

Identification of Small Molecules Selectively Targeting Leukemic Stem Cells within Their Stromal Niche

Alissa R. Kahn, MD, Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Benjamin L. Ebert, MD, PhD, Todd R. Golub, MD, Malcolm A.S. AS Moore

Blood (2012) 120 (21): 413.

https://doi.org/10.1182/blood.V120.21.413.413

Published: 2012

Journal Articles

Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma

Blood (2012) 120 (21): 571.

https://doi.org/10.1182/blood.V120.21.571.571

Published: 2012

Journal Articles

Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics

Blood (2011) 118 (21): 760.

https://doi.org/10.1182/blood.V118.21.760.760

Published: 2011

Journal Articles

The Mutational Landscape of Diffuse Large B Cell Lymphoma

Blood (2011) 118 (21): 259.

https://doi.org/10.1182/blood.V118.21.259.259

Published: 2011

Journal Articles

Selective Targeting of Leukemic Over Normal Stem Cells by the Serotonin Receptor Antagonist SB-216641

Alissa R. Kahn, MD, Kimberly A. Hartwell, PhD, Peter G. Miller, PhD, Benjamin L. Ebert, MD, D.Phil, Todd R. Golub, MD, Malcolm A.S. Moore, D.Phil

Blood (2011) 118 (21): 1884.

https://doi.org/10.1182/blood.V118.21.1884.1884

Published: 2011

Journal Articles

Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1

Blood (2011) 118 (21): 463.

https://doi.org/10.1182/blood.V118.21.463.463

Published: 2011

Journal Articles

Multiple Myeloma Sequencing Reveals Subclonality and Timing of Genetic Alterations

Jens Lohr, MD, PhD, Petar Stojanov, Michael S Lawrence, Daniel Auclair, PhD, Scott Carter, Carrie Sougnez, Joshua Gould, Peter Cruz-Gordillo, Michael A Chapman, Gad Getz, Todd R. Golub, MD

Blood (2011) 118 (21): 2897.

https://doi.org/10.1182/blood.V118.21.2897.2897

Published: 2011

Journal Articles

Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1

Bjoern Chapuy, MD, PhD, Michael R Green, PhD, Jun Lu, PhD, Stefano Monti, PhD, Yansheng Hao, MD, PhD, Kelly T Yeda, Scott J Rodig, Treeve Currie, Kunihiko Takeyama, MD, PhD, Todd R Golub, MD, PhD, Jeffery Kutok, MD, PhD, Margaret A. Shipp, MD

Blood (2010) 116 (21): 746.

https://doi.org/10.1182/blood.V116.21.746.746

Published: 2010

Journal Articles

Leukemic and Normal Stem Cell Transcriptional Signatures Determined by Functional Assays Are Predictive of the Overall Survival of AML Patients.

Kolja Eppert, MSc, PhD, Katsuto Takenaka, MD, Björn Nilsson, M.D., Ph.D., Eric R Lechman, M.Sc., Ph.D., Vicki Ling, MSc, Joseph Beyene, PhD, Angelo J Canty, PhD, Jayne S Danska, PhD, Mark D Minden, MD, Todd R. Golub, MD, Benjamin L Ebert, MD, PhD, John E Dick, PhD

Blood (2009) 114 (22): 389.

https://doi.org/10.1182/blood.V114.22.389.389

Published: 2009

Journal Articles

HOXA9 Is a Novel Therapeutic Target in Multiple Myeloma.

Michael A Chapman, Jean-Philippe Brunet, Jonathan J Keats, PhD, Angela Baker, Mazhar Adli, Anna C. Schinzel, Gregory Ahmann, BS, Harview Christina, Anna Moore, Vijayalakshmi Shanmugam, Louise M. Perkins, PhD, Daniel Auclair, PhD, William C. Hahn, MD, PhD, Bradley E. Bernstein, MD, Leif Bergsagel, Rafael Fonseca, John Carpten, Jeffrey Trent, Todd R. Golub, MD

Blood (2009) 114 (22): 832.

https://doi.org/10.1182/blood.V114.22.832.832

Published: 2009

Journal Articles

Genomics and Systems Biology.

Todd R. Golub, MD

Blood (2008) 112 (11): sci-51.

https://doi.org/10.1182/blood.V112.11.sci-51.sci-51

Published: 2008

Journal Articles

Interim Analyses of the MMRC Reference Collection Identifies Recurrent Genomic-Level Events in Multiple Myeloma and Demonstrates That CDKN2C/p18 Deletion Is the Pre-Eminent Copy Number Alteration in Poor Prognosis Disease

Michael A Chapman, Jean-Philippe Brunet, Angela Baker, Jonathan Keats, Gregory Ahmann, BS, Anna C Schinzel, PhD, Anna Moore, Vijayalakshmi Shanmugam, Louise M. Perkins, PhD, Daniel Auclair, PhD, William C. Hahn, M.D., Ph.D, P. Leif Bergsagel, MD, Rafael Fonseca, MD, John Carpten, Jeffrey Trent, Todd R. Golub, MD

Blood (2008) 112 (11): 497.

https://doi.org/10.1182/blood.V112.11.497.497

Published: 2008

NARROW

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Identification and Validation of Molecular Markers of Tumor Cell Resistance to Natural Killer Cells through CRISPR-Based Screens and Large-Scale Phenotypic Screens of Pooled Tumor Cell Lines

Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

The Somatic Cancer Genome

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Ex Vivo expansion Of Umbilical Cord Blood CD34+ Cells Under Hypoxic Conditions Using Novel Compound#999 With Cytokines

A Structural Basis for p53-Deficiency, Deregulated Cell Cycle and Unfavorable Outcome in Diffuse Large B-Cell Lymphoma

Identification of Small Molecules Selectively Targeting Leukemic Stem Cells within Their Stromal Niche

Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma

Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics

The Mutational Landscape of Diffuse Large B Cell Lymphoma

Selective Targeting of Leukemic Over Normal Stem Cells by the Serotonin Receptor Antagonist SB-216641

Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1

Multiple Myeloma Sequencing Reveals Subclonality and Timing of Genetic Alterations

Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1

Leukemic and Normal Stem Cell Transcriptional Signatures Determined by Functional Assays Are Predictive of the Overall Survival of AML Patients.

HOXA9 Is a Novel Therapeutic Target in Multiple Myeloma.

Genomics and Systems Biology.

Interim Analyses of the MMRC Reference Collection Identifies Recurrent Genomic-Level Events in Multiple Myeloma and Demonstrates That CDKN2C/p18 Deletion Is the Pre-Eminent Copy Number Alteration in Poor Prognosis Disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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