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Anna C. Schinzel
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Journal Articles

Inhibition of CDK4/CDK6 Sensitizes Myeloma to IMiD By Reducing the MEIS2 to Cereblon Ratio That Accelerates IKZF1 and IKZF3 Degradation

Xiangao Huang, PhD, David Jayabalan, BSMS, MSc, Maurizio Di Liberto, PhD, Zhengming Chen, PhD, Anna C Schinzel, PhD, Scott Ely, MD MPH, Adriana C Rossi, MD MHS, Roger N Pearse, MD PhD, Ekta Aneja, MBBS, Morton Coleman, MD, Joseph M Lane, MD, William C. Hahn, MD PhD, Tomer M Mark, MD MSc, Ruben Niesvizky, MD, Selina Chen-Kiang, PhD
Journal: Blood
Blood (2015) 126 (23): 500.
https://doi.org/10.1182/blood.V126.23.500.500
Published: 2015
Journal Articles

Sensitizing shRNA Screen for Molecular Targets in CDK4/CDK6-Based Combination Therapy in Multiple Myeloma

Xiangao Huang, PhD, Maurizio Di Liberto, PhD, David Chiron, PhD, Ruben Niesvizky, MD, Anna C. Schinzel, PhD, William C. Hahn, MD PhD, Selina Chen-Kiang, PhD
Journal: Blood
Blood (2014) 124 (21): 3440.
https://doi.org/10.1182/blood.V124.21.3440.3440
Published: 2014
Journal Articles

Synergistic Loss of IRF4 and Induction of IRF7 Sensitizes Primary Myeloma Cells to IMiD Killing by IFNβ in Prolonged Early G1 Arrest Induced by CDK4/CDK6 Inhibition

Xiangao Huang, PhD, David Jayabalan, B.S.M.S, Maurizio Di Liberto, Ph.D., Jackson D Harvey, B.S., Anna C. Schinzel, PhD, Tomer M Mark, MD, MSc, Mohamad Hussein, MD, Sophia Randolph, MD, PhD, William C. Hahn, MD, PhD, Ruben Niesvizky, MD, Selina Chen-Kiang, PhD
Journal: Blood
Blood (2012) 120 (21): 572.
https://doi.org/10.1182/blood.V120.21.572.572
Published: 2012
Journal Articles

Inhibition of c-Myc Expression and Function in Hematologic Malignancies

Ghayas C Issa, MD, Jake E Delmore, Michael R McKeown, Madeleine E Lemieux, Peter B Rahl, Hannah M. Jacobs, Efstathios Kastritis, MD, Timothy Gilpatrick, Ronald M Paranal, Jun Qi, Junwei Shi, Marta Chesi, Anna C. Schinzel, PhD, Christopher R. Vakoc, M.D., Ph.D., P.Leif Bergsagel, MD, Paul G. Richardson, MD, Richard Young, PhD, William C. Hahn, MD, PhD, Irene M. Ghobrial, MD, Kenneth C Anderson, MD, Andrew L. Kung, MD, PhD, Constantine S. Mitsiades, MD, PhD, James E Bradner, MD
Journal: Blood
Blood (2011) 118 (21): 1409.
https://doi.org/10.1182/blood.V118.21.1409.1409
Published: 2011
Journal Articles

Intersecting Chemical Genomic and Genetic Screens Identifies Glycogen Synthase Kinase-3α (GSK-3α) as a Modulator of Differentiation In Acute Myeloid Leukemia

Versha Banerji, MD, Kenneth N. Ross, PhD, Loretta S. Li, MD, Stacey M. Frumm, Anna C. Schinzel, PhD, Cynthia K. Hahn, Rose M. Kakoza, MD, Kwan T. Chow, Linda Ross, PhD, Haig Inguilizian, MD, Ilene Galinsky, ANP, Richard M Stone, MD, Daniel J DeAngelo, MD, PhD, William C. Hahn, MD, PhD, Andrew L. Kung, MD, PhD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2010) 116 (21): 1000.
https://doi.org/10.1182/blood.V116.21.1000.1000
Published: 2010
Journal Articles

HOXA9 Is a Novel Therapeutic Target in Multiple Myeloma.

Michael A Chapman, Jean-Philippe Brunet, Jonathan J Keats, PhD, Angela Baker, Mazhar Adli, Anna C. Schinzel, Gregory Ahmann, BS, Harview Christina, Anna Moore, Vijayalakshmi Shanmugam, Louise M. Perkins, PhD, Daniel Auclair, PhD, William C. Hahn, MD, PhD, Bradley E. Bernstein, MD, Leif Bergsagel, Rafael Fonseca, John Carpten, Jeffrey Trent, Todd R. Golub, MD
Journal: Blood
Blood (2009) 114 (22): 832.
https://doi.org/10.1182/blood.V114.22.832.832
Published: 2009
Journal Articles

NOVEL Pathways Modulate TUMOR CELL Susceptibility to NK CELLS.

Roberto Bellucci, Ph.D, Hong-Nam Nguyen, Allison Martin, Anna C. Schinzel, PhD, Stefan Heinrichs, PhD, William C. Hahn, MD, PhD, Jerome Ritz, MD
Journal: Blood
Blood (2009) 114 (22): 277.
https://doi.org/10.1182/blood.V114.22.277.277
Published: 2009
Journal Articles

High-Throughput RNA Interference Screening Identifies Synthetic Lethality Between Oncogenic KRAS Dependency and Suppression of STK33

Claudia Scholl, Stefan Frohling, Ian F. Dunn, David A. Barbie, Anna C. Schinzel, So Young Kim, Serena J. Silver, Lars Bullinger, Peter Sandy, Jesse S. Boehm, David E. Root, Tyler Jacks, William C. Hahn, D. Gary Gilliland
Journal: Blood
Blood (2008) 112 (11): 3806.
https://doi.org/10.1182/blood.V112.11.3806.3806
Published: 2008
Journal Articles

Interim Analyses of the MMRC Reference Collection Identifies Recurrent Genomic-Level Events in Multiple Myeloma and Demonstrates That CDKN2C/p18 Deletion Is the Pre-Eminent Copy Number Alteration in Poor Prognosis Disease

Michael A Chapman, Jean-Philippe Brunet, Angela Baker, Jonathan Keats, Gregory Ahmann, BS, Anna C Schinzel, PhD, Anna Moore, Vijayalakshmi Shanmugam, Louise M. Perkins, PhD, Daniel Auclair, PhD, William C. Hahn, M.D., Ph.D, P. Leif Bergsagel, MD, Rafael Fonseca, MD, John Carpten, Jeffrey Trent, Todd R. Golub, MD
Journal: Blood
Blood (2008) 112 (11): 497.
https://doi.org/10.1182/blood.V112.11.497.497
Published: 2008
Journal Articles

A High-Throughput Arrayed Lentiviral RNAi Screen To Identify Novel Oncogenes in Multiple Myeloma.

Anna C. Schinzel, PhD, Mike Chapman, MD, Ben Wittner, PhD, Yashaswi Shrestha, Sridhar Ramaswamy, MD, Todd R. Golub, MD, William C. Hahn, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 4770.
https://doi.org/10.1182/blood.V110.11.4770.4770
Published: 2007