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Journal Articles

KDM6A regulates immune response genes in multiple myeloma

Daphné Dupéré-Richer, Alberto Riva, Benjamin G. Barwick, Sayantan Maji, Heidi Casellas Román, Jianping Li, Umasankar De, Amin Sobh, Gabrielle Quickstad, Crissandra Piper, Marta Kulis, Teresa Ezponda, José Ignacio Martín-Subero, Giovanni Tonon, Weizhou Zhang, Constantine S. Mitsiades, Lawrence H. Boise, Richard L. Bennett, Jonathan D. Licht

Blood (2024) 144 (14): 1508–1520.

https://doi.org/10.1182/blood.2024024518

Published: 2024

Includes: Supplemental data

Journal Articles

Myeloma and DNA damage

Giovanni Tonon

Blood (2024) 143 (6): 488–495.

https://doi.org/10.1182/blood.2023021384

Published: 2024

Journal Articles

Time of Origin and Environmental Drivers of Leukemia Immune Escape after Transplantation

Cristina Toffalori, Riccardo Bergamin, Alice Antonello, Anna Francesca Tortorelli, Giorgio Orofino, Matteo Cristante, Lucrezia Della Volpe, Salvatore Milite, Nicola Calonaci, Giorgia Gandolfi, Aurora Maurizio, Raffaella Greco, Gabriele Bucci, Dejan Lazarevic, Raffaella Di Micco, Giovanni Tonon, Fabio Ciceri, Giulio Caravagna, Luca Vago

Blood (2023) 142 (Supplement 1): 362.

https://doi.org/10.1182/blood-2023-188623

Published: 2023

Journal Articles

The winding road toward the myeloma mouse

Giovanni Tonon

Blood (2021) 137 (1): 7–8.

https://doi.org/10.1182/blood.2020007942

Published: 2021

Journal Articles

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Elisa Sala, MD, Francesca Biavasco, MD, Gabriele Bucci, PhD, Cristina Toffalori, PhD, Donatella Biancolini, PhD, Elena Antonini, MSc, Matteo Giovanni Carrabba, MD, Bernhard Gentner, MD, Cristina Tresoldi, MSc, Massimo Bernardi, MD, Dejan Lazarevic, MD, Giovanni Tonon, MD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2019) 134 (Supplement_1): 511.

https://doi.org/10.1182/blood-2019-124725

Published: 2019

Journal Articles

Combining Whole Exome Sequencing and Rnaseq to Provide a Comprehensive Landscape of the Mechanisms of Post-Transplantation Leukemia Relapse

Lucia Zanotti, PhD, Gabriele Bucci, PhD, Francesco Santaniello, Cristina Toffalori, Donatella Biancolini, PhD, Ettore Zapparoli, Laura Zito, Matteo Giovanni Carrabba, MD, Friedrich Stoelzel, Martin Bornhäuser, Massimo Bernardi, MD, Jacopo Peccatori, Chiara Bonini, MD, Davide Cittaro, PhD, Dejan Lazarevic, Giovanni Tonon, MD PhD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2018) 132 (Supplement 1): 819.

https://doi.org/10.1182/blood-2018-99-111769

Published: 2018

Journal Articles

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Alessandra Romano, MDPhD, Laura Oliva, PhD, Jose Manuel Manteiga, Todoerti Katia, Lorenzo Canziani, Matteo Trudu, Francesca Fontana, Michela Ghizzinardi, Ugo Orfanelli, Magda Marcatti, MD, Fabio Ciceri, MD, Giovanni Tonon, MD PhD, Antonino Neri, MD, Claudio Cerichione, MD PhD, Francesco Di Raimondo, MD, Simone Cenci, MD

Blood (2017) 130 (Supplement 1): 3051.

https://doi.org/10.1182/blood.V130.Suppl_1.3051.3051

Published: 2017

Journal Articles

Profiling the Genomic Landscape at the Early Stages of CLL: Low Genomic Complexity and Paucity of Driver Mutations in MBL and Indolent CLL

Andreas Agathangelidis, Viktor Ljungström, Lydia Scarfò, Claudia Fazi, Maria Gounari, Tatiana Pandzic, Lesley-Ann Sutton, Kostas Stamatopoulos, MD PhD, Giovanni Tonon, Richard Rosenquist, MD PhD, Paolo Ghia

Blood (2016) 128 (22): 3214.

https://doi.org/10.1182/blood.V128.22.3214.3214

Published: 2016

Journal Articles

HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment

Roberta Valsecchi, Nadia Coltella, Daniela Belloni, Manfredi Ponente, Elisa ten Hacken, Cristina Scielzo, Lydia Scarfò, Maria Teresa Sabrina Bertilaccio, Paola Brambilla, Elisa Lenti, Filippo Martinelli Boneschi, Andrea Brendolan, Elisabetta Ferrero, Marina Ferrarini, Paolo Ghia, Giovanni Tonon, Maurilio Ponzoni, Federico Caligaris-Cappio, Rosa Bernardi

Blood (2016) 127 (16): 1987–1997.

https://doi.org/10.1182/blood-2015-07-657056

Published: 2016

Includes: Supplemental data

Journal Articles

Targeting Replicative Stress to Treat Hematological Disorders

Francesca Cottini, MD, Giovanni Tonon, MD PhD, Teru Hideshima, MD, PhD, Paul G. Richardson, MD, Kenneth C Anderson

Blood (2015) 126 (23): 2419.

https://doi.org/10.1182/blood.V126.23.2419.2419

Published: 2015

Journal Articles

The AP-1 Transcription Factor JunB Promotes Multiple Myeloma (MM) Cell Proliferation, Survival and Drug Resistance in the Bone Marrow Microenvironment

Fengjuan Fan, PhD, Sonia Vallet, MD, Martin Sattler, PhD, Giovanni Tonon, MDPhD, Muhammad Hasan Bashari, Latifa Bakiri, PhD, Hartmut Goldschmidt, MD, Erwin F. Wagner, PhD, Dirk Jaeger, MD, Klaus Podar, MD PhD

Blood (2014) 124 (21): 3446.

https://doi.org/10.1182/blood.V124.21.3446.3446

Published: 2014

Journal Articles

An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia

Panagiotis Ntziachristos, PhD, Aristotelis Tsirigos, Grant Welstead, Thomas Trimarchi, Linda Holmfeldt, PhD, Takashi Satoh, Elisabeth M. Paietta, PhD, Martin S. Tallman, MD, Jacob M. Rowe, MD, Giovanni Tonon, MDPhD, Jared Becksfort, MS, Laurens Kruidenier, Rab K Prinjha, Pieter Van Vlierberghe, Rudolph Jaenisch, PhD, Adolfo A. Ferrando, MD PhD, Charles G. Mullighan, MBBS, MSc, MD, Iannis Aifantis

Blood (2014) 124 (21): 56.

https://doi.org/10.1182/blood.V124.21.56.56

Published: 2014

Journal Articles

Angiogenesis Associated with Alterations of the Bone Marrow Microenvironment Predicts Multiple Myeloma Progression to Symptomatic Disease in Mice and Humans

Arianna Calcinotto, Maurilio Ponzoni, Roberto Ria, Matteo Grioni, Elena Cattaneo, Isabella Villa, Maria Teresa Sabrina Bertilaccio, Marta Chesi, PhD, Alessandro Rubinacci, Giovanni Tonon, MDPhD, Peter Leif Bergsagel, MD PhD, Angelo Vacca, MD PhD, Matteo Bellone, MD

Blood (2014) 124 (21): 5678.

https://doi.org/10.1182/blood.V124.21.5678.5678

Published: 2014

Journal Articles

Loss of the Histone Demethylase UTX Contributes to Multiple Myeloma and Sensitizes Cells to EZH2 Inhibitors

Teresa Ezponda, PhD, Relja Popovic, PhD, Yupeng Zheng, PhD, Behnam Nabet, Christine Will, MS, Eliza C Small, PhD, Manuela Occhionorelli, PhD, Giovanni Tonon, MDPhD, Jonathan J. Keats, PhD, Neil L Kelleher, PhD, Jonathan D. Licht

Blood (2014) 124 (21): 611.

https://doi.org/10.1182/blood.V124.21.611.611

Published: 2014

Journal Articles

Synthetic Lethal Approaches to Exploit Replicative Stress in Aggressive Myeloma

Francesca Cottini, Teru Hideshima, MDPhD, Rikio Suzuki, MDPhD, Paul G. Richardson, Kenneth C. Anderson, MD, Giovanni Tonon, MDPhD

Blood (2014) 124 (21): 173.

https://doi.org/10.1182/blood.V124.21.173.173

Published: 2014

Journal Articles

Serine/Threonine Kinase STK4 Is a Novel Target in Myeloma

Francesca Cottini, Teru Hideshima, MDPhD, Sara Buhrlage, PhD, Nathanael S. Gray, PhD, Paul G. Richardson, Giovanni Tonon, MDPhD, Kenneth C Anderson, MD

Blood (2014) 124 (21): 645.

https://doi.org/10.1182/blood.V124.21.645.645

Published: 2014

Journal Articles

The Oncogene MYC Triggers Replicative Stress and DNA Damage In Multiple Myeloma

Francesca Cottini, MD, Teru Hideshima, MD, PhD, Giovanni Tonon, MD, PhD, Kenneth C. Anderson, MD

Blood (2013) 122 (21): 3114.

https://doi.org/10.1182/blood.V122.21.3114.3114

Published: 2013

Journal Articles

The Role of the ABL1/YAP1/P73 Axis in Prevention of DNA Damage-Mediated Apoptosis in Multiple Myeloma

Francesca Cottini, Teru Hideshima, MD, PhD, Martin Sattler, PhD, Federico Caligaris-Cappio, MD, Kenneth C. Anderson, MD, Giovanni Tonon, MD PhD

Blood (2012) 120 (21): 725.

https://doi.org/10.1182/blood.V120.21.725.725

Published: 2012

Journal Articles

Metabolomics Identifies Potential Biomarkers of Multiple Myeloma Development and Progression

Francesca Fontana, MD, PhD, Josè Manuel garcia Manteiga, PhD, Magda Marcatti, MD, Francesca Lorentino, MD, Giovanni Tonon, MD, PhD, Fabio Ciceri, MD, Roberto Sitia, MD, Simone Cenci, MD

Blood (2012) 120 (21): 3985.

https://doi.org/10.1182/blood.V120.21.3985.3985

Published: 2012

Journal Articles

Targeting Mcl-1 for Multiple Myeloma (MM) Therapy: Drug-Induced Generation of Mcl-1 Fragment Mcl-1 128–350 Triggers MM Cell Death V ia c- Jun Upregulation

Fengjuan Fan, PhD, Giovanni Tonon, MD PhD, Martin Sattler, PhD, Alexander Schimming, Hartmut Goldschmidt, MD, PhD, Joseph Opferman, Ph.D, Kenneth C. Anderson, MD, Dirk Jaeger, MD, Klaus Podar, MD, PhD

Blood (2012) 120 (21): 3959.

https://doi.org/10.1182/blood.V120.21.3959.3959

Published: 2012

NARROW

KDM6A regulates immune response genes in multiple myeloma

Myeloma and DNA damage

Time of Origin and Environmental Drivers of Leukemia Immune Escape after Transplantation

The winding road toward the myeloma mouse

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Combining Whole Exome Sequencing and Rnaseq to Provide a Comprehensive Landscape of the Mechanisms of Post-Transplantation Leukemia Relapse

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Profiling the Genomic Landscape at the Early Stages of CLL: Low Genomic Complexity and Paucity of Driver Mutations in MBL and Indolent CLL

HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment

Targeting Replicative Stress to Treat Hematological Disorders

The AP-1 Transcription Factor JunB Promotes Multiple Myeloma (MM) Cell Proliferation, Survival and Drug Resistance in the Bone Marrow Microenvironment

An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia

Angiogenesis Associated with Alterations of the Bone Marrow Microenvironment Predicts Multiple Myeloma Progression to Symptomatic Disease in Mice and Humans

Loss of the Histone Demethylase UTX Contributes to Multiple Myeloma and Sensitizes Cells to EZH2 Inhibitors

Synthetic Lethal Approaches to Exploit Replicative Stress in Aggressive Myeloma

Serine/Threonine Kinase STK4 Is a Novel Target in Myeloma

The Oncogene MYC Triggers Replicative Stress and DNA Damage In Multiple Myeloma

The Role of the ABL1/YAP1/P73 Axis in Prevention of DNA Damage-Mediated Apoptosis in Multiple Myeloma

Metabolomics Identifies Potential Biomarkers of Multiple Myeloma Development and Progression

Targeting Mcl-1 for Multiple Myeloma (MM) Therapy: Drug-Induced Generation of Mcl-1 Fragment Mcl-1 128–350 Triggers MM Cell Death V ia c- Jun Upregulation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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