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Journal Articles

Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study

Blood (2021) 138 (16): 1429–1440.

https://doi.org/10.1182/blood.2021011719

Published: 2021

Includes: Supplemental data

Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Veronika Bachanova, MD PhD, David H. McKenna, MD, Xianghua Luo, PhD, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD MS, Erica D. Warlick, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Guy Brachya, PhD, Tony Peled, MSc, Jeffrey S. Miller, MD

Blood (2019) 134 (Supplement_1): 777.

https://doi.org/10.1182/blood-2019-130476

Published: 2019

Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc

Blood (2019) 134 (Supplement_1): 3718.

https://doi.org/10.1182/blood-2019-131124

Published: 2019

Journal Articles

Enhanced In Vivo Persistence and Proliferation of NK Cells Expanded in Culture with the Small Molecule Nicotinamide: Development of a Clinical-Applicable Method for NK Expansion

Tony Peled, Guy Brachya, Nurit Persi, Chana Lador, Esti Olesinski, Efrat Landau, Einat Galamidi, Amnon Peled, Jeffrey S. Miller, MD, Veronika Bachanova, MD PhD

Blood (2017) 130 (Supplement 1): 657.

https://doi.org/10.1182/blood.V130.Suppl_1.657.657

Published: 2017

Journal Articles

Successful Engraftment of Donor Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord® ( Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and a Second Unmanipulated Cord Blood Unit after Myeloablative Chemotherapy in Pediatric Patients with Severe Sickle Cell Disease

Suhag H Parikh, MD, Joel Brochstein, MD, Paul L. Martin, MD PhD, Mitchell E. Horwitz, MD, Einat Galamidi, MD, Iddo Peleg, MSc, MBA, Uri Goshen, M.MDSc., Aurelie Schwarzbach, MSc, David A. Snyder, PhD, Tony Peled, MSc, Joanne Kurtzberg, MD

Blood (2016) 128 (22): 3651.

https://doi.org/10.1182/blood.V128.22.3651.3651

Published: 2016

Journal Articles

StemEx®(Copper Chelation Based) Ex Vivo Expanded Umbilical Cord Blood Stem Cell Transplantation (UCBT) Accelerates Engraftment and Improves 100 Day Survival In Myeloablated Patients Compared To a Registry Cohort Undergoing Double Unit UCBT: Results Of a Multicenter Study Of 101 Patients With Hematologic Malignancies

Blood (2013) 122 (21): 295.

https://doi.org/10.1182/blood.V122.21.295.295

Published: 2013

Journal Articles

Improved Homing To Bone Marrow, Spleen and Lung Of Adoptively Infused NK Cells Expanded Ex Vivo With The Small Molecule Nicotinamide Using Feeder-Free Conditions

Gabi M. Frei, Maria Berg, Tony Peled, MSc, Robert N. Reger, Ritesh Kotecha, Toshihiro Onishi, MD, Luis Espinoza-Calderon, Nurit Persi, Chana Lador, Amnon Peled, Richard W. Childs, MD

Blood (2013) 122 (21): 897.

https://doi.org/10.1182/blood.V122.21.897.897

Published: 2013

Journal Articles

Nicotinamide (NAM) Increases Surface Expression of CD62L On in Vitro Expanded NK Cells

Ewelina K. Mamcarz, MD, Maria Berg, Tony Peled, Gabi M Frei, Robert Reger, Xin Tian, Ph.D., Richard Childs, MD

Blood (2012) 120 (21): 4355.

https://doi.org/10.1182/blood.V120.21.4355.4355

Published: 2012

Journal Articles

Nicotinamide, a Form of Vitamin B 3 , Promotes Expansion of Natural Killer Cells That Display Increased In Vivo Survival and Cytotoxic Activity,

Gabi M Frei, Nurit Persi, Chana Lador, Amnon Peled, PhD, Yael C Cohen, Arnon Nagler, Tony Peled

Blood (2011) 118 (21): 4035.

https://doi.org/10.1182/blood.V118.21.4035.4035

Published: 2011

Journal Articles

Nicotinamide, a Recognized Inhibitor of SIRT1, Promotes Expansion in Ex Vivo Cultures of Short and Long-Term Repopulating Cells.

Tony Peled, Hadas Shoham, Dorit Aschengrau, Dima Yackoubov, Gabi Frei, Arnon Nagler, Katia Beider, Amnon Peled

Blood (2009) 114 (22): 2431.

https://doi.org/10.1182/blood.V114.22.2431.2431

Published: 2009

Journal Articles

Experimental Double Cord Blood Transplantation (DCBT) of An Expanded Unit Together with a Non-Manipulated Unit in NOD/SCID Mice.

Tony Peled, Hadas Shoham, Oshrat Golan, Dorit Ashengrau, Dima Yaacobov, Gabi Frei, Arnon Nagler, Eitan Fibach, Amnon Peled

Blood (2008) 112 (11): 2313.

https://doi.org/10.1182/blood.V112.11.2313.2313

Published: 2008

Journal Articles

Antagonists to Retinoid Receptors Down-Regulate CD38 Expression and Inhibit In Vitro Differentiation of Cord Blood Derived CD34+ Cells.

Tony Peled, Ela Glukhman, Sophie Adi, Efrat Landau, Nira Hasson, Chana Lador, Julie Mandel, Eitan Fibach

Blood (2006) 108 (11): 3652.

https://doi.org/10.1182/blood.V108.11.3652.3652

Published: 2006

Journal Articles

Nicotinamide Modulates Ex-Vivo Expansion of Cord Blood Derived CD34+ Cells Cultured with Cytokines and Promotes Their Homing and Engraftment in SCID Mice.

Tony Peled, Sophie Adi, Iddo Peleg, Noga G. Rosenheimer, Yaron Daniely, Arnon Nagler, Eitan Fibach, Amnon Peled

Blood (2006) 108 (11): 725.

https://doi.org/10.1182/blood.V108.11.725.725

Published: 2006

Journal Articles

Ex-Vivo Expanded Human Bone Marrow-Derived AC133+ Cells To Treat Myocardial Infarction.

Frida Grynspan, Ph.D., Moshe Marikovsky, Ph.D., Efrat Landau, M.Sc., Tony Peled, Arnon Nagler, MD, Radka Holbova, Victor Guetta, MD, Shmuel Fuchs, MD, Shimon Feinberg, MD, Jonathan Leor, MD

Blood (2004) 104 (11): 154.

https://doi.org/10.1182/blood.V104.11.154.154

Published: 2004

NARROW

Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Enhanced In Vivo Persistence and Proliferation of NK Cells Expanded in Culture with the Small Molecule Nicotinamide: Development of a Clinical-Applicable Method for NK Expansion

Successful Engraftment of Donor Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord® ( Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and a Second Unmanipulated Cord Blood Unit after Myeloablative Chemotherapy in Pediatric Patients with Severe Sickle Cell Disease

Improved Homing To Bone Marrow, Spleen and Lung Of Adoptively Infused NK Cells Expanded Ex Vivo With The Small Molecule Nicotinamide Using Feeder-Free Conditions

Nicotinamide (NAM) Increases Surface Expression of CD62L On in Vitro Expanded NK Cells

Nicotinamide, a Form of Vitamin B 3 , Promotes Expansion of Natural Killer Cells That Display Increased In Vivo Survival and Cytotoxic Activity,

Nicotinamide, a Recognized Inhibitor of SIRT1, Promotes Expansion in Ex Vivo Cultures of Short and Long-Term Repopulating Cells.

Experimental Double Cord Blood Transplantation (DCBT) of An Expanded Unit Together with a Non-Manipulated Unit in NOD/SCID Mice.

Antagonists to Retinoid Receptors Down-Regulate CD38 Expression and Inhibit In Vitro Differentiation of Cord Blood Derived CD34+ Cells.

Nicotinamide Modulates Ex-Vivo Expansion of Cord Blood Derived CD34+ Cells Cultured with Cytokines and Promotes Their Homing and Engraftment in SCID Mice.

Ex-Vivo Expanded Human Bone Marrow-Derived AC133+ Cells To Treat Myocardial Infarction.

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American Society of Hematology

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American Society of Hematology

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