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Journal Articles

Antisense Oligonucleotide Mediated Depletion of Factor XI Prevents Vascular Occlusion in An Experimental Thrombosis Model in Primates

Jeff R. Crosby, PhD, Ulla M Marzec, MS, Chenguang Zhao, Dacao Gao, Alexey S Revenko, PhD, Anton Matafonov, MD, David Gailani, MD, Robert MacLeod, Ph.D., Andras Gruber, MD, Stephen Hanson, PhD, Brett P. Monia, PhD

Blood (2011) 118 (21): 2250.

https://doi.org/10.1182/blood.V118.21.2250.2250

Published: 2011

Journal Articles

A Locally Administered Novel Heparin Complex Attenuates Collagen-Induced Platelet Activation and Thrombosis In Vivo ,

Riitta Lassila, MD, PhD, Associate Professor, Annukka Jouppila, M.Sci, Ulla M Marzec, MS, Stephen R Hanson, PhD, Prof.

Blood (2011) 118 (21): 3361.

https://doi.org/10.1182/blood.V118.21.3361.3361

Published: 2011

Journal Articles

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Erik I. Tucker, PhD, Ulla M Marzec, MS, Philberta Y Leung, PhD, Stephen R Hanson, PhD, Prof., Norah G Verbout, PhD, Sawan Hurst, MS, Owen J.T. McCarty, PhD, David Gailani, MD, Andras Gruber, MD

Blood (2011) 118 (21): 1173.

https://doi.org/10.1182/blood.V118.21.1173.1173

Published: 2011

Journal Articles

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

Erik I. Tucker, Ulla M. Marzec, Tara C. White, Sawan Hurst, Sandra Rugonyi, Owen J. T. McCarty, David Gailani, András Gruber, Stephen R. Hanson

Blood (2009) 113 (4): 936–944.

https://doi.org/10.1182/blood-2008-06-163675

Published: 2009

Journal Articles

Potential of Activated Prothrombin Complex Concentrate and Activated Factor VII to Reverse the Anticoagulant Effects of Rivaroxaban in Primates

András Gruber, MD, Ulla M Marzec, Ulf Buetehorn, Stephen Hanson, PhD, Elisabeth Perzborn

Blood (2008) 112 (11): 3825.

https://doi.org/10.1182/blood.V112.11.3825.3825

Published: 2008

Journal Articles

Moderate Pharmacological Platelet Count Reduction Limits Thrombus Formation without Hemostatic Impairment in Primates

Erik I Tucker, Ulla M Marzec, Sawan Hurst, András Gruber, MD, Stephen R Hanson, PhD

Blood (2008) 112 (11): 1033.

https://doi.org/10.1182/blood.V112.11.1033.1033

Published: 2008

Journal Articles

Inhibition of Factor XI Decreases Thrombin Production and Prevents Vascular Occlusion in Experimental Thrombosis in Primates.

Erik I. Tucker, BS, Ulla M. Marzec, MS, Andras Gruber, MD, Stephen R. Hanson, PhD

Blood (2007) 110 (11): 763.

https://doi.org/10.1182/blood.V110.11.763.763

Published: 2007

Journal Articles

Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates

András Gruber, Ulla M. Marzec, Leslie Bush, Enrico Di Cera, José A. Fernández, Michelle A. Berny, Erik I. Tucker, Owen J. T. McCarty, John H. Griffin, Stephen R. Hanson

Blood (2007) 109 (9): 3733–3740.

https://doi.org/10.1182/blood-2006-07-035147

Published: 2007

Journal Articles

Thrombomodulin-Dependent Protein C Activator Treatment Improves the Short-Term Outcome of Experimental Ischemic Stroke in Mice.

Andras Gruber, MD, Patricia D. Hurn, PhD, Sawan Hurst, BS, Leslie Bush, MS, Ulla M. Marzec, MS, Erik Tucker, BS, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2006) 108 (11): 895.

https://doi.org/10.1182/blood.V108.11.895.895

Published: 2006

Journal Articles

Antithrombotic Activity of PRT54021, a Potent Oral Direct Factor Xa Inhibitor, Can Be Monitored Using a Novel Prothrombinase Inhibition Bioassay.

Uma Sinha, PhD, Susan T. Edwards, MS, Paul W. Wong, BS, Suzanne M. Delaney, PhD, Nisha Nanda, PhD, Ulla M. Marzec, MS, Yvonne Pak, PhD, Stanley J. Hollenbach, JD, Stephen R. Hanson, PhD

Blood (2006) 108 (11): 907.

https://doi.org/10.1182/blood.V108.11.907.907

Published: 2006

Journal Articles

Safe Interruption of Ongoing Thrombosis by the Protein C Activator Thrombin Analog, W215A/E217A; a Comparison to Enoxaparin in Primates.

Ulla M. Marzec, MS, Leslie Bush, MA, Erik Tucker, BS, Andras Gruber, MD, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2006) 108 (11): 909.

https://doi.org/10.1182/blood.V108.11.909.909

Published: 2006

Journal Articles

Subcutaneous Dosing of CRA-027483, a Small Molecule FVIIa Inhibitor, Prevents Arterial Thrombosis in a Baboon Model.

Ulla M. Marzec, Juthamas Sukbuntherng, Ph.D, Stacie A. Dalrymple, Ph.D, Wendy B. Young, Ph.D, Dange Vijaykumar, PhD, Peter R. Young, Ph.D, Stephen R. Hanson, PhD

Blood (2005) 106 (11): 1867.

https://doi.org/10.1182/blood.V106.11.1867.1867

Published: 2005

Journal Articles

Comparison of Enoxaparin to the Thrombin Variant Protein C Activator, W215A/E217A, in a Primate Model of Thrombosis.

Ulla M. Marzec, Leslie Bush, MA, Andras Gruber, MD, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2005) 106 (11): 1868.

https://doi.org/10.1182/blood.V106.11.1868.1868

Published: 2005

Journal Articles

Sustained Pharmacological Activation of Protein C (PC) in Baboons.

Andras Gruber, MD, Jose A. Fernandez, MD, PhD, Ulla M. Marzec, Leslie Bush, John H. Griffin, PhD, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2004) 104 (11): 3499.

https://doi.org/10.1182/blood.V104.11.3499.3499

Published: 2004

Journal Articles

Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers

Laurence A. Harker, Lorin K. Roskos, Ulla M. Marzec, Richard A. Carter, Judith K. Cherry, Birgitta Sundell, Ellen N. Cheung, Dixon Terry, William Sheridan

Blood (2000) 95 (8): 2514–2522.

https://doi.org/10.1182/blood.V95.8.2514

Published: 2000

Journal Articles

Treatment of Thrombocytopenia in Chimpanzees Infected With Human Immunodeficiency Virus by Pegylated Recombinant Human Megakaryocyte Growth and Development Factor

Laurence A. Harker, Ulla M. Marzec, Francis Novembre, I. Birgitta Sundell, Edmund K. Waller, Simon Karpatkin, Harold M. McClure, Andrew B. Kelly, Richard B. Stead

Blood (1998) 91 (12): 4427–4433.

https://doi.org/10.1182/blood.V91.12.4427

Published: 1998

Journal Articles

Ineffective Platelet Production in Thrombocytopenic Human Immunodeficiency Virus–Infected Patients

James L. Cole, Ulla M. Marzec, Clifford J. Gunthel, Simon Karpatkin, Lydia Worford, I. Birgitta Sundell, Jeffrey L. Lennox, Janet L. Nichol, Laurence A. Harker

Blood (1998) 91 (9): 3239–3246.

https://doi.org/10.1182/blood.V91.9.3239

Published: 1998

Journal Articles

Prevention of Thrombocytopenia and Neutropenia in a Nonhuman Primate Model of Marrow Suppressive Chemotherapy by Combining Pegylated Recombinant Human Megakaryocyte Growth and Development Factor and Recombinant Human Granulocyte Colony-Stimulating Factor

Laurence A. Harker, Ulla M. Marzec, Andrew B. Kelly, Ellen Cheung, Aaron Tomer, Janet L. Nichol, Stephen R. Hanson, Richard B. Stead

Blood (1997) 89 (1): 155–165.

https://doi.org/10.1182/blood.V89.1.155

Published: 1997

NARROW

Antisense Oligonucleotide Mediated Depletion of Factor XI Prevents Vascular Occlusion in An Experimental Thrombosis Model in Primates

A Locally Administered Novel Heparin Complex Attenuates Collagen-Induced Platelet Activation and Thrombosis In Vivo ,

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

Potential of Activated Prothrombin Complex Concentrate and Activated Factor VII to Reverse the Anticoagulant Effects of Rivaroxaban in Primates

Moderate Pharmacological Platelet Count Reduction Limits Thrombus Formation without Hemostatic Impairment in Primates

Inhibition of Factor XI Decreases Thrombin Production and Prevents Vascular Occlusion in Experimental Thrombosis in Primates.

Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates

Thrombomodulin-Dependent Protein C Activator Treatment Improves the Short-Term Outcome of Experimental Ischemic Stroke in Mice.

Antithrombotic Activity of PRT54021, a Potent Oral Direct Factor Xa Inhibitor, Can Be Monitored Using a Novel Prothrombinase Inhibition Bioassay.

Safe Interruption of Ongoing Thrombosis by the Protein C Activator Thrombin Analog, W215A/E217A; a Comparison to Enoxaparin in Primates.

Subcutaneous Dosing of CRA-027483, a Small Molecule FVIIa Inhibitor, Prevents Arterial Thrombosis in a Baboon Model.

Comparison of Enoxaparin to the Thrombin Variant Protein C Activator, W215A/E217A, in a Primate Model of Thrombosis.

Sustained Pharmacological Activation of Protein C (PC) in Baboons.

Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers

Treatment of Thrombocytopenia in Chimpanzees Infected With Human Immunodeficiency Virus by Pegylated Recombinant Human Megakaryocyte Growth and Development Factor

Ineffective Platelet Production in Thrombocytopenic Human Immunodeficiency Virus–Infected Patients

Prevention of Thrombocytopenia and Neutropenia in a Nonhuman Primate Model of Marrow Suppressive Chemotherapy by Combining Pegylated Recombinant Human Megakaryocyte Growth and Development Factor and Recombinant Human Granulocyte Colony-Stimulating Factor

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American Society of Hematology

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American Society of Hematology

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