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Journal Articles

Characterization of Complete Lncrnas Transcriptome Reveals Expression of Lncrnas As a Prognostic Factor and Linc-Smilo As a Potential Therapeutic Target in Multiple Myeloma

Arantxa Carrasco, Teresa Ezponda, Cem Meydan, PhD, Luis Vitores Valcárcel, MSc, Raquel Ordoñez, PhD, Marta Kulis, PhD, Leire Garate, Estíbaliz Miranda, Victor Segura, PhD, Elizabeth Guruceaga, Amaia Vilas-Zornoza, PhD, Diego Alignani, PhD, Laura Castro, Marien Pascual, PhD, Ane Amundarain, Halima El Omri, Ruba Yasin, MBBS, MRCP, Maria Jose Calasanz, PhD BSc, Francisco J Planes, Bruno Paiva, PhD, Christopher Mason, PhD, Jesús San-Miguel, Inaki Martin Subero, PhD, Ari M Melnick, MD, Felipe Prosper, MD PhD, Xabier Agirre, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4323.
https://doi.org/10.1182/blood-2019-123008
Published: 2019
Journal Articles

ZFP36L1, a Novel Potential Tumor Supressor Gene in Myelofibrosis, Epigenetically Deregulated By Methylation of the Enhancer Region

Nicolas Martinez-Calle, MD MSc, Marien Pascual, PhD, Raquel Ordoñez, MSc, Edurne San Jose Eneriz, PhD, Victor Segura, PhD, Giancarlo Castellano, PhD, Jose J. Rifon, MD, Maria Jose Calasanz, BSc, PhD, José I. Martin-Subero, PhD, Xabier Agirre, PhD, Felipe Prosper, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2936.
https://doi.org/10.1182/blood.V130.Suppl_1.2936.2936
Published: 2017
Journal Articles

New Insights into the Mechanism of Action (MoA) of First-in-Class IgG-Based Bcma T-Cell Bispecific Antibody (TCB) for the Treatment of Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Klaus Strein, MD PhD, Minh Diem Vu, PhD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 2096.
https://doi.org/10.1182/blood.V128.22.2096.2096
Published: 2016
Journal Articles

Critical Analysis on the Mechanism of Action (MoA) of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Daniel Ajona, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 2105.
https://doi.org/10.1182/blood.V128.22.2105.2105
Published: 2016
Journal Articles

High-Throughput Characterization and New Insight into the Role of Tumor Associated Macrophages (TAMs) in Multiple Myeloma (MM)

Paula Arana, Aintzane Zabaleta, Marta Lasa, Patricia Maiso, PhD, Diego Alignani, Tomas Jelinek, MD, Victor Segura, PhD, Wouter van den Bossche, Cristina Teodosio, Daniela Damasceno, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, Joan Bladé, Jacques J.M. van Dongen, MD PhD, Jesus San Miguel, MD PhD, Alberto Orfao, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 482.
https://doi.org/10.1182/blood.V128.22.482.482
Published: 2016
Journal Articles

Non-Invasive Genetic Profiling Is Highly Applicable in Multiple Myeloma (MM) through Characterization of Circulating Tumor Cells (CTCs)

Leire Burgos, Diego Alignani, Juan-Jose Garces, Lourdes Ortiz, Tomas Jelinek, MD, Victor Segura, PhD, Luzalba Sanoja, Maria-Jose Calasanz, Xabier Agirre, PhD, Felipe Prosper, MD, Paula Rodriguez-Otero, MD PhD, Rafael Rios, Joaquin Martinez-Lopez, Luis Palomera, MD PhD, Maria Teresa Zudaire, Rafael Del Orbe, MD, Jacques J.M. van Dongen, MD PhD, Alberto Orfao, MD PhD, Bruno Paiva, PhD, Jesus San Miguel, MD PhD
Journal: Blood
Blood (2016) 128 (22): 801.
https://doi.org/10.1182/blood.V128.22.801.801
Published: 2016
Journal Articles

Long Non-Coding RNAs Annotation and Their Involvement in Multiple Myeloma

Arantxa Carrasco, Teresa Ezponda, Cem Meydan, PhD, Marta Kulis, Raquel Ordoñez, Leire Garate, Victor Segura, PhD, Diego Alignani, Bruno Paiva, PhD, Jesus San Miguel, MD PhD, José I. Martin Subero, PhD, Ari Melnick, MD, Felipe Prosper, MD, Xabier Agirre, PhD
Journal: Blood
Blood (2016) 128 (22): 4420.
https://doi.org/10.1182/blood.V128.22.4420.4420
Published: 2016
Journal Articles

Whole-Genome Epigenomic Analysis in Multiple Myeloma Reveals DNA Hypermethylation of B-Cell Specific Enhancers

Xabier Agirre, PhD, Giancarlo Castellano, Marien Pascual, Simon Health, Marta Kulis, Victor Segura, PhD, Anke Bergmann, Anna Esteve, Angelika Merkel, Emanuele Raineri, Lidia Agueda, Julie Blanc, David Richardson, Laura Clarke, Nuria Russiñol, Ana C. Queirós, Renée Beekman, Juan R. Rodriguez-Madoz, Edurne San José-Enériz, PhD, Fang Fang, Norma Carmen Gutierrez, PhD MD, José M García-Verdugo, Michael I. Robson, Eric C. Schirmer, Elisabeth Guruceaga, Joost H.A. Martens, Marta Gut, María José Calasanz, PhD, Paul Flicek, Reiner Siebert, Elias Campo, MD PhD, Jesus F. San Miguel, Ari M Melnick, MD, Hendrik G. Stunnenberg, Ivo G. Gut, Felipe Prosper, MD, Jose Ignacio Martín-Subero
Journal: Blood
Blood (2014) 124 (21): 2032.
https://doi.org/10.1182/blood.V124.21.2032.2032
Published: 2014
Journal Articles

Unraveling a novel transcription factor code determining the human arterial-specific endothelial cell signature

Xabier L. Aranguren, Xabier Agirre, Manu Beerens, Giulia Coppiello, Maialen Uriz, Ine Vandersmissen, Mohammed Benkheil, Joaquin Panadero, Natalia Aguado, Alberto Pascual-Montano, Victor Segura, Felipe Prósper, Aernout Luttun
Journal: Blood
Blood (2013) 122 (24): 3982–3992.
https://doi.org/10.1182/blood-2013-02-483255
Published: 2013
Includes: Supplemental data
Journal Articles

Homeobox NKX2-3 Is Over-Expressed in Human B-Cell Lymphomas and Drives Marginal Zone B-Cell Lymphomagenesis in Mice

Eloy F Robles, PhD, Beatriz Aldaz, MSc, Takashi Akasaka, MD, PhD, Laura Macri Pellizzeri, MSc, Eduardo Martinez-Anso, PhD, Xavier Aguirre, PhD, Felipe Prosper, MD, Idoia Martin-Guerrero, PhD, Victor Segura, PhD, Maria José Calasanz, PhD, Isidro Sanchez-Garcia, MD, Elena Campos-Sanchez, MSc, Cesar Cobaleda, PhD, Charlotte Cresson, MSc, Cyril Broccardo, PhD, Reiner Siebert, Prof., Dr. med., Xabier Sagaert, MD, Martin JS Dyer, MA, DPhil, FRCP, FRCPath, Jose A Martinez-Climent, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 260.
https://doi.org/10.1182/blood.V118.21.260.260
Published: 2011
Journal Articles

HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation

Xiaoyu Jiang, PhD, Isabel Romero-Camarero, Ph.D, Xiaoqing Lu, M.D, Carolina Vicente-Dueñas, Ines Gonzalez-Herrero, Teresa Flores, Juan Luis Garcia, George McNamara, Ph.D, Christian Kunder, Yasodha Natkunam, MD, PhD, Victor Segura, PhD, Lorenna Fontan-Gabas, Jose A Martinez-Climent, MD, PhD, Ash A Alizadeh, MD/PhD, Cesar Cobaleda, PhD, Isidro Sanchez-Garcia, MD, Izidore S Lossos, MD
Journal: Blood
Blood (2011) 118 (21): 584.
https://doi.org/10.1182/blood.V118.21.584.584
Published: 2011
Journal Articles

Preclinical Activity of LBH589 Alone or in Combination with Chemotherapy in a Xenogeneic Mouse Model of Human Acute Lymphoblastic Leukemia

Xabier Agirre, PhD, Amaia Vilas-Zornoza, PhD, Gloria Abizanda, Cristina Moreno, Victor Segura, PhD, Alba De Martino Rodriguez, Edurne San José-Enériz, Estíbaliz Miranda, José Ignacio Martín-Subero, Leire Garate, María J. Blanco-Prieto, José A. García de Jalón, Jose J. Rifon, MD, Jose A Martinez-Climent, MD, PhD, Juan Cruz Cigudosa, José Román-Gómez, Maria José Calasanz, PhD, Josep-Maria Ribera, MD, PhD, Felipe Prosper, MD
Journal: Blood
Blood (2011) 118 (21): 1520.
https://doi.org/10.1182/blood.V118.21.1520.1520
Published: 2011