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Vincent Muczynski
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Journal Articles

NVG-222: A First-in-Class Autoregulating Half-Life Extended ROR1xCD3 T Cell Engager Heralding a New Class of Safer Drugs

David Granger, Vincent Muczynski, Patricia Henne, Annalisa Baccaro, Dinusha Fernando, Mittal Shah, John Devlin, Kieran O'Donovan, Amit C. Nathwani
Journal: Blood
Blood (2023) 142 (Supplement 1): 2820.
https://doi.org/10.1182/blood-2023-189058
Published: 2023
Journal Articles

AAV-Mediated Expression of a Single-Chain FVIII Mimetic Antibody Efficiently Corrects Bleeding in Haemophilia a Mice

Vincent Muczynski, Eric Bun, Lewis Tanner, Jenny H. McIntosh, Olivier D. Christophe, Amit C. Nathwani
Journal: Blood
Blood (2023) 142 (Supplement 1): 482.
https://doi.org/10.1182/blood-2023-186285
Published: 2023
Journal Articles

Pre-Clinical Development of a First in Class Half-Life Extended T Cell Engager Targeting ROR-1

David Granger, Patricia Henne, Annalisa Baccaro, Dinusha Fernando, Jasmine Gore, Ephraim Gbajumo, Vincent Muczynski, Mittal Shah, Kieran O'Donovan, Kerry Chester, Amit C. Nathwani
Journal: Blood
Blood (2022) 140 (Supplement 1): 7810–7811.
https://doi.org/10.1182/blood-2022-168961
Published: 2022
Journal Articles

A FVIII-Mimetic Bispecific Antibody with an Embedded Self-Regulation Mechanism Reduces the Risk of Prothrombotic Events for the Treatment of Haemophilia a

Vincent Muczynski, Angel Smith, Thibaud Sefiane, Olivier D. Christophe, Peter J. Lenting, David Granger, Kerry Chester, Amit C. Nathwani
Journal: Blood
Blood (2022) 140 (Supplement 1): 677–678.
https://doi.org/10.1182/blood-2022-169482
Published: 2022
Journal Articles

A hemophilia A mouse model for the in vivo assessment of emicizumab function

Stephen Ferrière, Ivan Peyron, Olivier D. Christophe, Charlotte Kawecki, Caterina Casari, Vincent Muczynski, Amit Nathwani, Alexandre Kauskot, Peter J. Lenting, Cécile V. Denis
Journal: Blood
Blood (2020) 136 (6): 740–748.
https://doi.org/10.1182/blood.2019004334
Published: 2020
Includes: Supplemental data
Journal Articles

A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation

Brief Report
Vincent Muczynski, Caterina Casari, François Moreau, Gabriel Aymé, Charlotte Kawecki, Paulette Legendre, Valerie Proulle, Olivier D. Christophe, Cécile V. Denis, Peter J. Lenting
Journal: Blood
Blood (2018) 132 (11): 1193–1197.
https://doi.org/10.1182/blood-2018-01-829523
Published: 2018
Includes: Supplemental data
Journal Articles

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions

Vincent Muczynski, Gabriel Aymé, Véronique Regnault, Marc Vasse, Delphine Borgel, Paulette Legendre, Amine Bazaa, Amélie Harel, Cécile Loubière, Peter J. Lenting, Cécile V. Denis, Olivier D. Christophe
Journal: Blood
Blood (2017) 129 (17): 2443–2454.
https://doi.org/10.1182/blood-2016-06-724351
Published: 2017
Includes: Supplemental data
Journal Articles

Von Willebrand Factor Interaction with FVIII: Development of Long Acting FVIII Therapies

Peter J Lenting, PhD, Vincent Muczynski, PhD, Gabriel Aymé, PhD, Cecile V. Denis, PhD, Olivier D. Christophe, PhD
Journal: Blood
Blood (2016) 128 (22): SCI-8.
https://doi.org/10.1182/blood.V128.22.SCI-8.SCI-8
Published: 2016
Journal Articles

Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X

Vincent Muczynski, Amine Bazaa, Cécile Loubière, Amélie Harel, Ghislaine Cherel, Cécile V. Denis, Peter J. Lenting, Olivier D. Christophe
Journal: Blood
Blood (2016) 127 (6): 778–786.
https://doi.org/10.1182/blood-2015-05-647032
Published: 2016
Includes: Supplemental data