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Journal Articles

Glucagon-like Peptide-2 (GLP-2) Treatment Reduces Gvhd-Related Mortality in a Pre-Clinical Transplant Model Via Expansion of Macrophages with Tolerogenic Potential

David W Harle, BBiomedSc, Rodney J Macedo Gonzales, MD PhD, Felix D Rozenberg, BSc, Alexandra Matschiner, Rajat Bansal, MD, Stephen M Lagana, MD, Huihui Ma, MD PhD, Elisha Pinker, Kirubel S Belay, BSc, Ximi K Wang, BSc, Tiffany Thomas, PhD, Markus Y Mapara, MD PhD, Anne-Catrin Uhlemann, MD, Yi Zhang, MD PhD, Ran Reshef, MDMSc

Blood (2020) 136 (Supplement 1): 26–28.

https://doi.org/10.1182/blood-2020-143105

Published: 2020

Journal Articles

Graft-Versus-Host Disease Causes the Failure of Donor Hematopoietic Progenitor Cells to Reconstitute Plasmacytoid Dendritic Cells That Promote Tolerance of Donor T Cells Against the Host

Yuanyuan Tian, Lijun Meng, PhD, Hongshuang Yu, Ying Wang, PhD, Tien Bui, Shin Mineishi, MD, Hong Zheng, MD PhD, Stefania Gallucci, MD, Yanyun Zhang, Shaoyan Hu, MD PhD, Yi Zhang, MD PhD

Blood (2019) 134 (Supplement_1): 193.

https://doi.org/10.1182/blood-2019-128721

Published: 2019

Journal Articles

Artesunate Inhibits Graft-Versus-Host Disease in Mice Via a Mechanism of Inducing Mitochondrial Calcium Overloading in Activated T Cells

Ying Wang, PhD, Shan He, PhD, Yongnian Liu, Robert Hooper, PhD, Hongshuang Yu, Yuanyuan Tian, Bui Tien, Bryant M Schultz, John W Elrod, PhD, Jonathan Soboloff, Yi Zhang, MD PhD

Blood (2019) 134 (Supplement_1): 4432.

https://doi.org/10.1182/blood-2019-131115

Published: 2019

Journal Articles

Low Levels of Plasmacytoid Dendritic Cells at the Time of Engraftment Are a Valuable Severe aGVHD Indicator in Children Undergoing Allogeneic Stem Cell Transplantation

Bohan Li, Xinran Chu, Lijun Meng, PhD, Peifang Xiao, MD, Jie Li, MD, Jun Lu, MD, Yi Zhang, MD PhD, Shaoyan Hu, MD PhD

Blood (2019) 134 (Supplement_1): 3288.

https://doi.org/10.1182/blood-2019-128191

Published: 2019

Journal Articles

MLL Histone Methyltransferase Restrains Effector Differentiation and PD-1 Expression in Human CD8 + T Cells While Promoting Their Proliferation

Janaki Purushe, Hongxin Sun, PhD, Shan He, PhD, Yali Dou, PhD, Yi Zhang, MD, PhD

Blood (2016) 128 (22): 863.

https://doi.org/10.1182/blood.V128.22.863.863

Published: 2016

Journal Articles

The Epigenetic Regulator Ezh2 Is An Effective Target For Controlling Th1 Cell-Mediated Acquired Aplastic Anemia In Mice

Qing Tong, MD, Shan He, PhD, Fang Xie, Amanda Wong, Kazuhiro Mochizuki, MD, PhD, Yongnian Liu, MS, Izumi Mochizuki, MD, Shin Mineishi, MD, Yi Zhang, MD, PhD

Blood (2013) 122 (21): 2467.

https://doi.org/10.1182/blood.V122.21.2467.2467

Published: 2013

Journal Articles

The Histone Methyltransferase Ezh2 Is a Crucial Epigenetic Regulator Of Allogeneic T Cell Responses and Graft-Versus-Host Disease In Mice

Shan He, PhD, Fang Xie, Yongnian Liu, MS, Qing Tong, MS, Kazuhiro Mochizuki, MD, PhD, Philip E Lapinski, PhD, Pavan Reddy, MD, Izumi Mochizuki, MD, Arul M. Chinnaiyan, MD, PhD, Shin Mineishi, MD, Philip D King, PhD, Yi Zhang, MD, PhD

Blood (2013) 122 (21): 137.

https://doi.org/10.1182/blood.V122.21.137.137

Published: 2013

Journal Articles

Identification of Previously Uncharacterized Delta 4-Positive Inflammatory Plasmacytoid Dendritic Cells That Play Important Roles in Eliciting Graft-Versus-Host Disease in Mice

Kazuhiro Mochizuki, MD, PhD, Fang Xie, MD, Shan He, PhD, Qing Tong, MS, Yongnian Liu, MS, Yajun Guo, MD, PhD, Koji Kato, MD, PhD, Hideo Yagita, PhD, Shin Mineishi, Yi Zhang, MD, PhD

Blood (2012) 120 (21): 337.

https://doi.org/10.1182/blood.V120.21.337.337

Published: 2012

Journal Articles

Histone Methyltransferase Ezh2 Controls T-Cell Immunity by Regulating Bioenergetic Metabolism

Shan He, PhD, Fang Xie, MD, Qing Tong, MS, Kazuhiro Mochizuki, MD, PhD, Yongnian Liu, MS, Philip E Lapinski, PhD, Shin Mineishi, Ram Shankar Mani, MD, Victor E Marquez, Arul M. Chinnaiyan, MD, PhD, Philip D King, PhD, Yi Zhang, MD, PhD

Blood (2012) 120 (21): 953.

https://doi.org/10.1182/blood.V120.21.953.953

Published: 2012

Journal Articles

Inhibition of Histone Methylation Arrests Ongoing Graft-Versus-Host Diseases in Mice by Selectively Inducing Apoptosis of Alloreactive Effector T Cells

Shan He, PhD, Jina Wang, MD, Koji Kato, MD, PhD, Fang Xie, MD, Sooryanarayana Varambally, MD, Shin Mineishi, MD, Rork Kuick, MS, Kazuhiro Mochizuki, MD, Yongnian Liu, MS, Evelyn Nieves, PhD, Ram Mani, MD, Arul M. Chinnaiyan, MD, PhD, Victor E. Marquez, PhD, Yi Zhang, MD, PhD

Blood (2011) 118 (21): 820.

https://doi.org/10.1182/blood.V118.21.820.820

Published: 2011

Journal Articles

Inhibition of Notch Signaling in T Cells Prevents Immune-Mediated Bone Marrow Failure.

Gloria T Shan, BS, Ivy Tran, Ashley R Sandy, BS, Ann Friedman, BS, Yi Zhang, MD, PhD, Ivan Maillard, MD, PhD

Blood (2009) 114 (22): 180.

https://doi.org/10.1182/blood.V114.22.180.180

Published: 2009

Journal Articles

Alloreactive CD8 + Effector T Cells Proliferate and Persist Upon Chronic Exposure to Alloantigens through Reactivation of Stem Cell Transcriptional Programs.

Koji Kato, MD, Shuaiying Cui, Rork Kuick, Shin Mineishi, MD, Elizabeth Hexner, MD, James LM Ferrara, MD, DSc, Victor E Marquez, PhD, Stephen G. Emerson, MD, PhD, Yi Zhang, MD, PhD

Blood (2009) 114 (22): 2444.

https://doi.org/10.1182/blood.V114.22.2444.2444

Published: 2009

Journal Articles

Notch Signaling Is a Critical Regulator of Allogeneic T Cell Responses Mediating Graft-Versus-Host Disease.

Yi Zhang, MD, PhD, Ashley R Sandy, BS, Jina Wang, Koji Kato, MD, Shan He, Ivy Tran, Gloria Tran Shan, Ann Friedman, Elizabeth Hexner, MD, Stephen G. Emerson, MD, PhD, Warren S. Pear, MD, PhD, Ivan Maillard, MD, PhD

Blood (2009) 114 (22): 230.

https://doi.org/10.1182/blood.V114.22.230.230

Published: 2009

Journal Articles

Down Regulation of CXC Chemokine Receptor 3 Impedes the Ability of Anti-CXCR3 Antibody To Block Graft-Versus-Host Disease.

Shan He, MA, Qi Cao, MA, Min Jin, BA, Stephen G. Emerson, MD, PhD, Yi Zhang, MD, PhD, Yanyun Zhang, MD, PhD

Blood (2007) 110 (11): 3235.

https://doi.org/10.1182/blood.V110.11.3235.3235

Published: 2007

Journal Articles

Host-Reactive Donor CD8+ T Memory Stem Cells but Not Mature T Memory Cells Primed Against Leukemic Cells Mediate Potent Graft-Versus-Leukemia Effect.

Elizabeth O. Hexner, MD, Dale Frank, MD, Stephen G. Emerson, MD, PhD, Yi Zhang, MD, PhD

Blood (2006) 108 (11): 190.

https://doi.org/10.1182/blood.V108.11.190.190

Published: 2006

Journal Articles

Bone Marrow Derived, De Novo Generated CD4+ T Cells Are Previously Unsuspected Participants in CD8+ T Cell-Mediated Graft-Versus-Host Disease.

Yi Zhang, MD, PhD, Elizabeth Hexner, MD, Dale Frank, MD, Joe Gerard, BS, Frank Kung, BS, Stephen G. Emerson, MD, Ph.D

Blood (2005) 106 (11): 581.

https://doi.org/10.1182/blood.V106.11.581.581

Published: 2005

NARROW

Glucagon-like Peptide-2 (GLP-2) Treatment Reduces Gvhd-Related Mortality in a Pre-Clinical Transplant Model Via Expansion of Macrophages with Tolerogenic Potential

Graft-Versus-Host Disease Causes the Failure of Donor Hematopoietic Progenitor Cells to Reconstitute Plasmacytoid Dendritic Cells That Promote Tolerance of Donor T Cells Against the Host

Artesunate Inhibits Graft-Versus-Host Disease in Mice Via a Mechanism of Inducing Mitochondrial Calcium Overloading in Activated T Cells

Low Levels of Plasmacytoid Dendritic Cells at the Time of Engraftment Are a Valuable Severe aGVHD Indicator in Children Undergoing Allogeneic Stem Cell Transplantation

MLL Histone Methyltransferase Restrains Effector Differentiation and PD-1 Expression in Human CD8 + T Cells While Promoting Their Proliferation

The Epigenetic Regulator Ezh2 Is An Effective Target For Controlling Th1 Cell-Mediated Acquired Aplastic Anemia In Mice

The Histone Methyltransferase Ezh2 Is a Crucial Epigenetic Regulator Of Allogeneic T Cell Responses and Graft-Versus-Host Disease In Mice

Identification of Previously Uncharacterized Delta 4-Positive Inflammatory Plasmacytoid Dendritic Cells That Play Important Roles in Eliciting Graft-Versus-Host Disease in Mice

Histone Methyltransferase Ezh2 Controls T-Cell Immunity by Regulating Bioenergetic Metabolism

Inhibition of Histone Methylation Arrests Ongoing Graft-Versus-Host Diseases in Mice by Selectively Inducing Apoptosis of Alloreactive Effector T Cells

Inhibition of Notch Signaling in T Cells Prevents Immune-Mediated Bone Marrow Failure.

Alloreactive CD8 + Effector T Cells Proliferate and Persist Upon Chronic Exposure to Alloantigens through Reactivation of Stem Cell Transcriptional Programs.

Notch Signaling Is a Critical Regulator of Allogeneic T Cell Responses Mediating Graft-Versus-Host Disease.

Down Regulation of CXC Chemokine Receptor 3 Impedes the Ability of Anti-CXCR3 Antibody To Block Graft-Versus-Host Disease.

Host-Reactive Donor CD8+ T Memory Stem Cells but Not Mature T Memory Cells Primed Against Leukemic Cells Mediate Potent Graft-Versus-Leukemia Effect.

Bone Marrow Derived, De Novo Generated CD4+ T Cells Are Previously Unsuspected Participants in CD8+ T Cell-Mediated Graft-Versus-Host Disease.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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