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Shuaiying Cui
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Journal Articles

SR-18292 Induces Fetal Hemoglobin Synthesis and Reduces Disease Pathology in Sickle Cell Mice

Yanan Sun, Hajar Benmhammed, Alawi Habara, Martin H. Steinberg, Shuaiying Cui
Journal: Blood
Blood (2023) 142 (Supplement 1): 5258.
https://doi.org/10.1182/blood-2023-186314
Published: 2023
Journal Articles

Targeting Transcriptional Co-Activator PGC-1a for the Treatment of Sickle Cell Disease

Alawi Habara, MBBS, MSc, Cuong LE, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, Shuaiying Cui, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2254.
https://doi.org/10.1182/blood-2019-123959
Published: 2019
Journal Articles

Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis

Cuong Quang Le, Greggory Myers, Alawi Habara, Natee Jearawiriyapaisarn, George J. Murphy, David H. K. Chui, Martin H. Steinberg, James Douglas Engel, Shuaiying Cui
Journal: Blood
Blood (2019) 133 (22): 2455–2459.
https://doi.org/10.1182/blood.2018892737
Published: 2019
Includes: Supplemental data
Journal Articles

Regulating Transcriptional Co-Activator PGC-1α for the Treatment of Sickle Cell Disease

Alawi Habara, MBBS, MSc, Cuong LE, PhD, George J Murphy, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, Shuaiying Cui, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2358.
https://doi.org/10.1182/blood-2018-99-111022
Published: 2018
Journal Articles

LSD1 Inhibitors Induce Fetal Hemoglobin in Primary Human Erythroid Cells

Cuong LE, PhD, Greggory Myers, Alawi Habara, MBBS, MSc, David H.K. Chui, MD, Martin H. Steinberg, MD, James Douglas Engel, PhD, Shuaiying Cui, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1066.
https://doi.org/10.1182/blood-2018-99-117675
Published: 2018
Journal Articles

A Long Noncoding RNA from the HBS1L-MYB Intergenic Region on Chr6q23 Regulates Human Fetal Hemoglobin Expression

Tasha A. Morrison, MPH,BA, Ibifiri Wilcox, BS, Hong-Yuan Luo, PhD, John Farrell, PhD, Ryo Kurita, PhD, Yukio Nakamura, MD PhD, George J Murphy, PhD, Shuaiying Cui, PhD, Martin H. Steinberg, MD, David H.K. Chui, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 288.
https://doi.org/10.1182/blood.V130.Suppl_1.288.288
Published: 2017
Journal Articles

In Vivo Effects of LSD1 Inhibition By Small Chemical Inhibitors in Sickle Cell Mice

Cuong Le, PhD, Greggory Myers, Alawi Habara, Natee Jearawiriyapaisarn, PhD, Mary Lee, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, James Engel, PhD, Shuaiying Cui, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 968.
https://doi.org/10.1182/blood.V130.Suppl_1.968.968
Published: 2017
Journal Articles

Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons

Vinzon Ibanez, Kestis Vaitkus, Angela Rivers, Robert Molokie, Shuaiying Cui, James Douglas Engel, Joseph DeSimone, Donald Lavelle
Journal: Blood
Blood (2017) 129 (2): 260–263.
https://doi.org/10.1182/blood-2016-10-746727
Published: 2017
Journal Articles

Activity of RN-1, an LSD-1 Inhibitor, on Fetal Globin Expression in Sickle Mice and Sickle Erythroid Progenitors

Shuaiying Cui, PhD, Jose Sangerman, PhD, Seyed Mehdi Nouraie, MD, PhD, Yan Dai, PhD, Oluwakemi Owoyemi, MD MPH, Robert E. Taylor, MD PhD, Susan P. Perrine, MD
Journal: Blood
Blood (2015) 126 (23): 961.
https://doi.org/10.1182/blood.V126.23.961.961
Published: 2015
Journal Articles

The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice

Shuaiying Cui, Kim-Chew Lim, Lihong Shi, Mary Lee, Natee Jearawiriyapaisarn, Greggory Myers, Andrew Campbell, David Harro, Shigeki Iwase, Raymond C. Trievel, Angela Rivers, Joseph DeSimone, Donald Lavelle, Yogen Saunthararajah, James Douglas Engel
Journal: Blood
Blood (2015) 126 (3): 386–396.
https://doi.org/10.1182/blood-2015-02-626259
Published: 2015
Includes: Supplemental data
Journal Articles

Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes

Shuaiying Cui, Osamu Tanabe, Michael Sierant, Lihong Shi, Andrew Campbell, Kim-Chew Lim, James Douglas Engel
Journal: Blood
Blood (2015) 125 (9): 1477–1487.
https://doi.org/10.1182/blood-2014-10-605022
Published: 2015
Includes: Supplemental data
Journal Articles

Improved Anemia, Organomegaly and Sustained Fetal Hemoglobin Induction within Aging TR2/TR4 Overexpressing UAB Sickle Cell Mice

Andrew Campbell, MD, Kori Bradley, Ama Amachong, Jennifer Addo, Rebekah Urbonya, Kwaku Osei Bonsu, David Harro, David Giacherio, Ph.D, Lihong Shi, PhD, Shuaiying Cui, Ph.D, Osamu Tanabe, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3248.
https://doi.org/10.1182/blood.V120.21.3248.3248
Published: 2012
Journal Articles

Notch signaling is a critical regulator of allogeneic CD4 + T-cell responses mediating graft-versus-host disease

Yi Zhang, Ashley R. Sandy, Jina Wang, Vedran Radojcic, Gloria T. Shan, Ivy T. Tran, Ann Friedman, Koji Kato, Shan He, Shuaiying Cui, Elizabeth Hexner, Dale M. Frank, Stephen G. Emerson, Warren S. Pear, Ivan Maillard
Journal: Blood
Blood (2011) 117 (1): 299–308.
https://doi.org/10.1182/blood-2010-03-271940
Published: 2011
Includes: Supplemental data
Journal Articles

Alloreactive CD8 + Effector T Cells Proliferate and Persist Upon Chronic Exposure to Alloantigens through Reactivation of Stem Cell Transcriptional Programs.

Koji Kato, MD, Shuaiying Cui, Rork Kuick, Shin Mineishi, MD, Elizabeth Hexner, MD, James LM Ferrara, MD, DSc, Victor E Marquez, PhD, Stephen G. Emerson, MD, PhD, Yi Zhang, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2444.
https://doi.org/10.1182/blood.V114.22.2444.2444
Published: 2009