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Journal Articles

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Yongsheng Huang, Kajal Sitwala, Joel Bronstein, Daniel Sanders, Monisha Dandekar, Cailin Collins, Gordon Robertson, James MacDonald, Timothee Cezard, Misha Bilenky, Nina Thiessen, Yongjun Zhao, Thomas Zeng, Martin Hirst, Alfred Hero, Steven Jones, Jay L. Hess

Blood (2012) 119 (2): 388–398.

https://doi.org/10.1182/blood-2011-03-341081

Published: 2012

Includes: Supplemental data

Journal Articles

Hoxa9 and Meis1 Bind Highly Conserved Elements Near Targets Regulated in Leukemia Cells.

Kajal V. Sitwala, M.D., Ph.D., Yongsheng Huang, Monisha Dandekar, M.D., Gordon Robertson, Ph.D., Timothee Cezard, Misha Bilenky, Ph.D., Nina Thiessen, Yongjun Zhao, Thomas Zeng, Martin Hirst, Ph.D., Alfred Hero, Ph.D., Steven Jones, Ph.D., Jay Hess, M.D., Ph.D.

Blood (2008) 112 (11): 3362.

https://doi.org/10.1182/blood.V112.11.3362.3362

Published: 2008

Journal Articles

Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

George Mulligan, Constantine Mitsiades, Barb Bryant, Fenghuang Zhan, Wee J. Chng, Steven Roels, Erik Koenig, Andrew Fergus, Yongsheng Huang, Paul Richardson, William L. Trepicchio, Annemiek Broyl, Pieter Sonneveld, John D. Shaughnessy, Jr, P. Leif Bergsagel, David Schenkein, Dixie-Lee Esseltine, Anthony Boral, Kenneth C. Anderson

Blood (2006) 109 (8): 3177–3188.

https://doi.org/10.1182/blood-2006-09-044974

Published: 2006

Includes: Supplemental data

Journal Articles

Metaphase Cytogenetics Adds to Gene Expression Profiling in the Identification of High Risk Multiple Myeloma.

Guido Tricot, MD, PhD, Fenghuang Zhan, MD, PhD, Bart Barlogie, MD, PhD, Yongsheng Huang, PhD, Jeffrey Sawyer, PhD, John Shaughnessy, PhD

Blood (2006) 108 (11): 114.

https://doi.org/10.1182/blood.V108.11.114.114

Published: 2006

Journal Articles

A Validated Gene Expression Signature of High Risk Multiple Myeloma Is Defined by Deregulated Expression of Genes Mapping to Chromosome 1.

John D. Shaughnessy, Jr., Fenghuang Zhan, Bart Burington, Yongsheng Huang, Ichiro Hanamura, James P. Stewart, Klaus Hollmig, Mauricio Pineda-Roman, Guido Tricot, Frits van Rhee, Maurizio Zangari, John Crowley, Bart Barlogie

Blood (2006) 108 (11): 111.

https://doi.org/10.1182/blood.V108.11.111.111

Published: 2006

Journal Articles

CKS1B, Mapping to an Amplicon on Chromosome 1q21 and over Expressed in Aggressive Disease, Regulates Multiple Myeloma Growth and Survival through p27 Kip1 -Dependent and Independent Mechanisms.

Fenghuang Zhan, Simona Colla, James B. Chen, James P. Stewart, Xiaosong Wu, Yongsheng Huang, Ichiro Hanamura, Bart Burington, Shmuel Yaccoby, Joshua Epstein, Bart Barlogie, John D. Shaughnessy, Jr.

Blood (2006) 108 (11): 3408.

https://doi.org/10.1182/blood.V108.11.3408.3408

Published: 2006

Journal Articles

An Update on the Role of Thalidomide (THAL) in Total Therapy 2 (TT2) for Newly Diagnosed Patients with Multiple Myeloma (MM): Analysis of Subgroups Defined by Standard Prognostic Factors (SPF) and Gene Expression Profiling (GEP)-Derived Subgroups.

John D. Shaughnessy, Jr., Jeffrey Haessler, Jerry Zeldis, Yongsheng Huang, Fenghuang Zhan, Jeffrey Sawyer, Elias Anaissie, Frits van Rhee, Guido Tricot, Joshua Epstein, Maurizio Zangari, Mauricio Pineda-Roman, Klaus Hollmig, John Crowley, Bart Barlogie

Blood (2006) 108 (11): 3389.

https://doi.org/10.1182/blood.V108.11.3389.3389

Published: 2006

Journal Articles

Testing Standard and Genetic Markers in 220 Patients with Multiple Myeloma (MM) with Complete Data Sets: Superiority of Molecular Genetics.

John D. Shaughnessy, Jr., Jeffrey Haessler, Ichiro Hanamura, Yongsheng Huang, James P. Stewart, Fenghuang Zhan, Jeffrey Sawyer, Elias Anaissie, Frits van Rhee, Guido Tricot, Joshua Epstein, Maurizio Zangari, Mauricio Pineda-Roman, Klaus Hollmig, John Crowley, Bart Barlogie

Blood (2006) 108 (11): 3391.

https://doi.org/10.1182/blood.V108.11.3391.3391

Published: 2006

Journal Articles

DNA Repair Genes Are Upregulated in Multiple Myeloma (MM) Patients Relapsing after Tandem Transplantation.

Guido Tricot, MD, PhD, Fenghuang Zhan, MD, PhD, Yongsheng Huang, PhD, Bart Barlogie, MD, PhD, John Shaughnessy, PhD

Blood (2006) 108 (11): 3392.

https://doi.org/10.1182/blood.V108.11.3392.3392

Published: 2006

Journal Articles

A Gene Expression Signature of Benign Monoclonal Gammopathy Evident in Multiple Myeloma Is Linked to Good Prognosis.

Fenghuang Zhan, Bart Barlogie, Varant Arzoumanian, Yongsheng Huang, Klaus Hollmig, Mauricio Pineda-Roman, Guido Tricot, Frits van Rhee, Maurizio Zangari, Madhav Dhodapkar, John D. Shaughnessy, Jr.

Blood (2006) 108 (11): 3393.

https://doi.org/10.1182/blood.V108.11.3393.3393

Published: 2006

Journal Articles

TP53 Gene Expression, Correlated with 17p13 Deletion, Is a Significant and Independent Adverse Prognostic Factor in Multiple Myeloma Treated with High-Dose Therapy and Auto-Transplants.

Wei Xiong, Fenghuang Zhan, Yongsheng Huang, Bart Barlogie, John D. Shaughnessy, Jr.

Blood (2006) 108 (11): 3394.

https://doi.org/10.1182/blood.V108.11.3394.3394

Published: 2006

Journal Articles

Evaluation of NCAM and DKK1 Expression in Multiple Myeloma and MGUS by Gene and Tissue Microarrays: Expression Accompanies Progression.

Sushil Gupta, Yongsheng Huang, James Stewart, Fenghuang Zhan, Bart Barlogie, John D. Shaughnessy, Jr.

Blood (2006) 108 (11): 3399.

https://doi.org/10.1182/blood.V108.11.3399.3399

Published: 2006

Journal Articles

CS1 Is Expressed on Myeloma Cells from Early Stage, Late Stage, and Drug-Treated Multiple Myeloma Patients, and Is Selectively Targeted by the HuLuc63 Antibody.

Susann Szmania, BS, Balaji Balasa, PhD, Priyangi Malaviarachchi, BS, Fenguhuang Zhan, MD,PhD, Yongsheng Huang, MS, Aparna Draksharapu, MD, Vladimir Vexler, PhD, John Shaughnessy, Jr., PhD, Bart Barlogie, MD,PhD, Guido Tricot, MD,PhD, Daniel Afar, PhD, van Rhee Frits, MD,PhD

Blood (2006) 108 (11): 660.

https://doi.org/10.1182/blood.V108.11.660.660

Published: 2006

Journal Articles

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1

Blood (2006) 109 (6): 2276–2284.

https://doi.org/10.1182/blood-2006-07-038430

Published: 2006

Journal Articles

Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis

Fenghuang Zhan, Bart Barlogie, Varant Arzoumanian, Yongsheng Huang, David R. Williams, Klaus Hollmig, Mauricio Pineda-Roman, Guido Tricot, Frits van Rhee, Maurizio Zangari, Madhav Dhodapkar, John D. Shaughnessy, Jr

Blood (2006) 109 (4): 1692–1700.

https://doi.org/10.1182/blood-2006-07-037077

Published: 2006

Includes: Supplemental data

Journal Articles

The molecular classification of multiple myeloma

Blood (2006) 108 (6): 2020–2028.

https://doi.org/10.1182/blood-2005-11-013458

Published: 2006

Includes: Supplemental data

Journal Articles

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation

Ichiro Hanamura, James P. Stewart, Yongsheng Huang, Fenghuang Zhan, Madhumita Santra, Jeffrey R. Sawyer, Klaus Hollmig, Maurizio Zangarri, Mauricio Pineda-Roman, Frits van Rhee, Federica Cavallo, Bart Burington, John Crowley, Guido Tricot, Bart Barlogie, John D. Shaughnessy, Jr

Blood (2006) 108 (5): 1724–1732.

https://doi.org/10.1182/blood-2006-03-009910

Published: 2006

Includes: Supplemental data

Journal Articles

Beta-Catenin and N-Cadherin in Myeloma: Implications for Adhesion and Migration.

Fenghuang Zhan, MD, PhD, Simona Colla, PhD, Ya-Wei Qiang, MD, PhD, Owen Stephens, BS, Yongsheng Huang, MS, Bart Barlogie, MD, PhD, John Shaughnessy, Jr., PhD

Blood (2005) 106 (11): 2497.

https://doi.org/10.1182/blood.V106.11.2497.2497

Published: 2005

Journal Articles

Gene Expression Profiling (GEP) in Multiple Myeloma (MM): Comparison of Purified MM Cells (PMM), Random Bone Marrow Biopsies (RBX) and Fine Needle Biopsies from Focal Lesions (FNBX).

Yongsheng Huang, Fenghuang Zhan, Bart Barlogie, John Shaughnessy

Blood (2005) 106 (11): 1535.

https://doi.org/10.1182/blood.V106.11.1535.1535

Published: 2005

Journal Articles

Frequent Gains of Chromosome Arm 1q21 in Plasma Cell Dyscrasia Detected by Fluorescence In Situ Hybridization: Incidence Increases from MGUS to Relapsed Myeloma and Is Related to Disease Progression and Prognosis.

Ichiro Hanamura, MD, Peter Stewart, PhD, Frederica Cavallo, MD, Bart Burington, MS, Erik Rasmussen, MS, John Crowley, PhD, Fenghuang Zhan, MD, PhD, Yongsheng Huang, MS, Bart Barlogie, MD, PhD, John Shaughnessy, PhD

Blood (2005) 106 (11): 1553.

https://doi.org/10.1182/blood.V106.11.1553.1553

Published: 2005

NARROW

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Hoxa9 and Meis1 Bind Highly Conserved Elements Near Targets Regulated in Leukemia Cells.

Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

Metaphase Cytogenetics Adds to Gene Expression Profiling in the Identification of High Risk Multiple Myeloma.

A Validated Gene Expression Signature of High Risk Multiple Myeloma Is Defined by Deregulated Expression of Genes Mapping to Chromosome 1.

CKS1B, Mapping to an Amplicon on Chromosome 1q21 and over Expressed in Aggressive Disease, Regulates Multiple Myeloma Growth and Survival through p27 Kip1 -Dependent and Independent Mechanisms.

An Update on the Role of Thalidomide (THAL) in Total Therapy 2 (TT2) for Newly Diagnosed Patients with Multiple Myeloma (MM): Analysis of Subgroups Defined by Standard Prognostic Factors (SPF) and Gene Expression Profiling (GEP)-Derived Subgroups.

Testing Standard and Genetic Markers in 220 Patients with Multiple Myeloma (MM) with Complete Data Sets: Superiority of Molecular Genetics.

DNA Repair Genes Are Upregulated in Multiple Myeloma (MM) Patients Relapsing after Tandem Transplantation.

A Gene Expression Signature of Benign Monoclonal Gammopathy Evident in Multiple Myeloma Is Linked to Good Prognosis.

TP53 Gene Expression, Correlated with 17p13 Deletion, Is a Significant and Independent Adverse Prognostic Factor in Multiple Myeloma Treated with High-Dose Therapy and Auto-Transplants.

Evaluation of NCAM and DKK1 Expression in Multiple Myeloma and MGUS by Gene and Tissue Microarrays: Expression Accompanies Progression.

CS1 Is Expressed on Myeloma Cells from Early Stage, Late Stage, and Drug-Treated Multiple Myeloma Patients, and Is Selectively Targeted by the HuLuc63 Antibody.

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1

Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis

The molecular classification of multiple myeloma

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation

Beta-Catenin and N-Cadherin in Myeloma: Implications for Adhesion and Migration.

Gene Expression Profiling (GEP) in Multiple Myeloma (MM): Comparison of Purified MM Cells (PMM), Random Bone Marrow Biopsies (RBX) and Fine Needle Biopsies from Focal Lesions (FNBX).

Frequent Gains of Chromosome Arm 1q21 in Plasma Cell Dyscrasia Detected by Fluorescence In Situ Hybridization: Incidence Increases from MGUS to Relapsed Myeloma and Is Related to Disease Progression and Prognosis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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