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Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 99.
https://doi.org/10.1182/blood-2019-125359
Published: 2019
Journal Articles

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biophysical Forces of Blood Flow

Lindsay N. Theodore, BS, Vanessa Lundin, PhD, Paul J. Wrighton, PhD, Andrew G. Cox, PhD, Patricia Sousa, Wolfram Goessling, MD PhD, Donald E. Ingber, MD PhD, George Q. Daley, MD PhD, Trista E. North, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1147.
https://doi.org/10.1182/blood.V130.Suppl_1.1147.1147
Published: 2017
Journal Articles

Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation

Diamantis G. Konstantinidis, Katie M. Giger, Mary Risinger, Suvarnamala Pushkaran, Ping Zhou, Phillip Dexheimer, Satwica Yerneni, Paul Andreassen, Ursula Klingmüller, James Palis, Yi Zheng, Theodosia A. Kalfa
Journal: Blood
Blood (2015) 126 (12): 1473–1482.
https://doi.org/10.1182/blood-2014-12-616169
Published: 2015
Includes: Supplemental data
Journal Articles

Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness

Yongzhi Qiu, PhD, Ashley C Brown, PhD, David R Myers, PhD, Yumiko Sakurai, MSc, Robert Mannino, BS, Reginald Tran, BS, Byungwook Ahn, PhD, Elaissa Hardy, PhD, Matthew F Kee, Sanjay Kumar, MD, PhD, Gang Bao, PhD, Thomas H Barker, PhD, Wilbur A Lam, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1438.
https://doi.org/10.1182/blood.V124.21.1438.1438
Published: 2014
Journal Articles

RhoA Gtpase Regulates Erythroblast Cytokinesis and Enucleation By Dynamic Coordination Of The Microtubule-Actomyosin Machineries For Successful Abscission

Diamantis G. Konstantinidis, PhD, Suvarnamala Pushkaran, M.Sc., Katie M. Giger, PhD, Ping Zhou, B.S., Paul R. Andreassen, PhD, Ursula Klingmuller, PhD, James Palis, M.D., Yi Zheng, PhD, Theodosia A. Kalfa, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 311.
https://doi.org/10.1182/blood.V122.21.311.311
Published: 2013
Journal Articles

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue

Max Lerchenberger, Bernd Uhl, Konstantin Stark, Gabriele Zuchtriegel, Annekathrin Eckart, Meike Miller, Daniel Puhr-Westerheide, Marc Praetner, Markus Rehberg, Alexander G. Khandoga, Kirsten Lauber, Steffen Massberg, Fritz Krombach, Christoph A. Reichel
Journal: Blood
Blood (2013) 122 (5): 770–780.
https://doi.org/10.1182/blood-2012-12-472944
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

Hyperangiotensinemia Induces Stem Cell/Progenitor Mobilization and De-Adhesion From BM Endothelial Cells Through AT2R Signaling and Inhibition of RhoA Activity

Kyung-Hee Chang, PhD, Ramesh C Nayak, Ph.D., Katie Bezold, Ashley Ficker, Swarnava Roy, PhD, Xuan Zhou, Megan Pirman, Susan Dunn, Yi Zheng, PhD, Punam Malik, MD, Jose A. Cancelas, M.D. PhD
Journal: Blood
Blood (2012) 120 (21): 3466.
https://doi.org/10.1182/blood.V120.21.3466.3466
Published: 2012
Journal Articles

Erythroid Specific RhoA Deficiency Causes Dysplastic and Inefficient Fetal Erythropoiesis with Lethal Embryonic Anemia Due to Defects in Erythroblast Cytokinesis and Enucleation

Diamantis Konstantinidis, PhD, Suvarnamala Pushkaran, M.Sc., Ursula Klingmuller, PhD, James Palis, MD, Yi Zheng, PhD, Theodosia A Kalfa, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 82.
https://doi.org/10.1182/blood.V120.21.82.82
Published: 2012
Journal Articles

RhoA Is An Essential Regulator of Mitosis and Survival During Hematopoietic Stem Cell Differentiation to Multipotent Progenitors

Xuan Zhou, Jaime Meléndez, Yuxin Feng, Richard Lang, Yi Zheng
Journal: Blood
Blood (2011) 118 (21): 1273.
https://doi.org/10.1182/blood.V118.21.1273.1273
Published: 2011
Journal Articles

RhoA GTPase Is Dispensable for Hematopoietic Stem Cell Maintenance but Essential for Multipotent Progenitor and Lower Hierarchical Hematopoietic Differentiation.

Xuan Zhou, Jaime Melendez, Yuxin Feng, Richard Lang, Yi Zheng
Journal: Blood
Blood (2010) 116 (21): 2618.
https://doi.org/10.1182/blood.V116.21.2618.2618
Published: 2010
Journal Articles

Loss of the WASP-Interacting Protein, CIP4, Results In Murine Thrombocytopenia: Insights Into the Pathophysiology of WASP-Related Thrombocytopenia

Jorie Aardema, Zak Whichard, Ted Strom, MD, PhD, David Rawlings, MD, PhD, Seth J. Corey, MD
Journal: Blood
Blood (2010) 116 (21): 382.
https://doi.org/10.1182/blood.V116.21.382.382
Published: 2010
Journal Articles

HGAL Directly Interacts with Both Myosin and Actin and Increases the Binding of Myosin to Actin

Xiaoqing Lu, MD, Kazmierczak Katarzyna, Ph.D, Xiaoyu Jiang, PhD, James Watt, Jeffrey R Moore, Ph.D, Danuta Szczesna-Cordary, Ph.D, Izidore S Lossos, MD
Journal: Blood
Blood (2010) 116 (21): 3097.
https://doi.org/10.1182/blood.V116.21.3097.3097
Published: 2010
Journal Articles

Caspase Activated Rock-1 Allows Erythroblasts Enucleation Independently of Cytokine Signaling

Genevieve Courtois, Julie Vandekerckhove, Yunhua Chang, jean-Antoine Ribeil, Joelle Kersual, Najet Debili, William Vainchenker, Bruno R. Varet, MD, Olivier Hermine
Journal: Blood
Blood (2008) 112 (11): 2885.
https://doi.org/10.1182/blood.V112.11.2885.2885
Published: 2008