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Journal Articles

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets

Shailaja Hegde, Huzoor Akbar, Ashley M. Wellendorf, Shawnagay Nestheide, James F. Johnson, Xueheng Zhao, Kenneth D. Setchell, Yi Zheng, Jose A. Cancelas

Blood (2024) 144 (16): 1732–1746.

https://doi.org/10.1182/blood.2023021453

Published: 2024

Includes: Supplemental data

Journal Articles

Conditioning for alloengraftment in FA

Yi Zheng

Blood (2024) 143 (21): 2120–2122.

https://doi.org/10.1182/blood.2024024447

Published: 2024

Journal Articles

Homozygous CEBPA Mutations Predict Favorable Outcomes in AML Patients

Lili PAN, Shenglong Lin, Yi Zheng, Yixin Ma, Yining Li, Yuwei Xie, Yuanhua Cai, Xiaofan Li, Shaoyuan Wang

Blood (2023) 142 (Supplement 1): 2850.

https://doi.org/10.1182/blood-2023-184624

Published: 2023

Journal Articles

Efficacy, Safety, and Population Pharmacokinetics of Eltrombopag in Children with Different Severities of Aplastic Anemia

Wei Zhang, Li-xian Chang, Bei-bei Zhao, Dan-dan Shan, Bo-hao Tang, Fan Yang, Yue Zhou, Guo-xiang Hao, Yi Zheng, Ya-hui Zhang, John Van Den Anker, Xiaofan Zhu, Li Zhang, Wei Zhao

Blood (2023) 142 (Supplement 1): 1345.

https://doi.org/10.1182/blood-2023-181581

Published: 2023

Journal Articles

Conserved and Unique Regulatory Mechanisms of RUNX1 in Hematopoietic Stem/Progenitor Cell Subpopulations in Both Normal Hematopoiesis and FPD/AML Development

Chen Wang, Yi Zheng, Cuiqing Fan, Zhaowei Tu, Xiongwei Cai, Jianqiang Wu, Gang Huang

Blood (2023) 142 (Supplement 1): 1314.

https://doi.org/10.1182/blood-2023-190129

Published: 2023

Journal Articles

Targeting G3BP2 Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment Via ELF1-MCL1 Axis

Zhixiang Chen, Yuanhua Cai, Xiaolin Lai, Xuechun Wang, Xiongbin Yan, Yaping Wang, Fuquan Tu, Wanting Wu, Yang Li, Lili Pan, Yi Zheng, Jinggang Li, Xiaofan Li, Shaoyuan Wang

Blood (2023) 142 (Supplement 1): 410.

https://doi.org/10.1182/blood-2023-178489

Published: 2023

Journal Articles

Identification of a Novel FAM135B Cancer Susceptibility Mutation in a Family with Multiple Cases of MLL -Rearranged AML

Li-li PAN, Yanling Sun, Xiaolin Lai, Luya Ye, Xue-chun Wang, Zhi-xiang Chen, Yuanhua Cai, Yi Zheng, Yang Li, Ya-ping Wang, Xin Liu, Shao-yuan Wang, Qian-fei Wang

Blood (2022) 140 (Supplement 1): 9107.

https://doi.org/10.1182/blood-2022-165170

Published: 2022

Journal Articles

Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis

Laurel Romano, Katie G. Seu, Julien Papoin, David E. Muench, Diamantis Konstantinidis, André Olsson, Katrina Schlum, Kashish Chetal, Joel Anne Chasis, Narla Mohandas, Betsy J. Barnes, Yi Zheng, H. Leighton Grimes, Nathan Salomonis, Lionel Blanc, Theodosia A. Kalfa

Blood (2022) 140 (14): 1621–1634.

https://doi.org/10.1182/blood.2022015724

Published: 2022

Includes: Supplemental data

Journal Articles

Structure-Activity Relationship Analysis of Analogs of Rhosin, a RhoA Inhibitor, Reveals a New Generation of Improved Antiplatelet Agents

Akhila Dandamudi, William Seibel, Huzoor Akbar, Yi Zheng

Blood (2021) 138 (Supplement 1): 3989.

https://doi.org/10.1182/blood-2021-153108

Published: 2021

Journal Articles

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

Zhaowei Tu, Chen Wang, Ashley K. Davis, Mengwen Hu, Chuntao Zhao, Mei Xin, Q. Richard Lu, Yi Zheng

Blood (2021) 138 (3): 221–233.

https://doi.org/10.1182/blood.2020009997

Published: 2021

Includes: Supplemental data

Journal Articles

Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice

Yue Sheng, Rui Ma, Chunjie Yu, Qiong Wu, Steven Zhang, Kimberly Paulsen, Jiwang Zhang, Hongyu Ni, Yong Huang, Yi Zheng, Zhijian Qian

Blood (2021) 137 (5): 610–623.

https://doi.org/10.1182/blood.2019004688

Published: 2021

Includes: Supplemental data

Journal Articles

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Chen Wang, MD, Weinan Wang, BS, Lei Huang, PhD, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-140769

Published: 2020

Journal Articles

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate

Mark J. Althoff, Ramesh C. Nayak, Shailaja Hegde, Ashley M. Wellendorf, Breanna Bohan, Marie-Dominique Filippi, Mei Xin, Q. Richard Lu, Hartmut Geiger, Yi Zheng, Maria T. Diaz-Meco, Jorge Moscat, Jose A. Cancelas

Blood (2020) 136 (16): 1824–1836.

https://doi.org/10.1182/blood.2019004113

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD

Blood (2019) 134 (Supplement_1): 1191.

https://doi.org/10.1182/blood-2019-127313

Published: 2019

Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 99.

https://doi.org/10.1182/blood-2019-125359

Published: 2019

Journal Articles

The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph + (BCR-ABL1) B-ALL

Nicolas Nassar, PhD, Shailaja N Hegde, PhD, Anjelika Gasilina, Mark Wunderlich, MS, Gurdat Premnauth, Edward Merino, PhD, Yuan Lin, PhD, Reza Ahmadian, PhD, Yi Zheng, PhD, Benjamin Mizukawa, Lisa Privette Vinnedge, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 4647.

https://doi.org/10.1182/blood-2019-130250

Published: 2019

Journal Articles

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Timothy M Chlon, PhD, Emily Stepanchick, Kwangmin Choi, PhD, Yi Zheng, PhD, Kathleen Hueneman, Ashley Davis, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 773.

https://doi.org/10.1182/blood-2019-127471

Published: 2019

Journal Articles

Precision Assessment of on- and Off-Target Effects of mTOR Kinase Inhibitors in a Mouse Model

Cuiqing Fan, PhD, Xiongwei Cai, PhD, Feng Zhang, PhDcandidate, Cindy Hochstetler, PhDcandidate, Xiaoyi Chen, PhD, Fukun Guo, PhD, Weidong Tian, PhD, Yi Zheng, PhD

Blood (2018) 132 (Supplement 1): 2632.

https://doi.org/10.1182/blood-2018-99-115225

Published: 2018

Journal Articles

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Shailaja N Hegde, PhD, Mark J Althoff, BS, Ramesh C. Nayak, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Gang Huang, PhD, Yi Zheng, PhD, Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD

Blood (2018) 132 (Supplement 1): 551.

https://doi.org/10.1182/blood-2018-99-118919

Published: 2018

Journal Articles

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

Chen Wang, PhDcandidate, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD

Blood (2018) 132 (Supplement 1): 1325.

https://doi.org/10.1182/blood-2018-99-116919

Published: 2018

NARROW

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets

Conditioning for alloengraftment in FA

Homozygous CEBPA Mutations Predict Favorable Outcomes in AML Patients

Efficacy, Safety, and Population Pharmacokinetics of Eltrombopag in Children with Different Severities of Aplastic Anemia

Conserved and Unique Regulatory Mechanisms of RUNX1 in Hematopoietic Stem/Progenitor Cell Subpopulations in Both Normal Hematopoiesis and FPD/AML Development

Targeting G3BP2 Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment Via ELF1-MCL1 Axis

Identification of a Novel FAM135B Cancer Susceptibility Mutation in a Family with Multiple Cases of MLL -Rearranged AML

Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis

Structure-Activity Relationship Analysis of Analogs of Rhosin, a RhoA Inhibitor, Reveals a New Generation of Improved Antiplatelet Agents

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph + (BCR-ABL1) B-ALL

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Precision Assessment of on- and Off-Target Effects of mTOR Kinase Inhibitors in a Mouse Model

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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