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Shailaja Hegde
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Journal Articles

ZE74-0282 is a novel JH2 domain JAK2 inhibitor with promising pre-clinical activity in JAK2 V617F mutant diseases

Free
Shailaja Hegde, Alexander Khvat, Ruben Karapetian, Brian Ledwith, Fraser Pickersgill, Megan Johnstone, Eric Vick, Emily Curran, Iain Dukes, Amy Burd, Nikolay Savchuk, Vladislav Parchincky, Igor Rezekin, Erin Hertlein, John Byrd
Journal: Blood
Blood (2025) 146 (Supplement 1): 1988.
https://doi.org/10.1182/blood-2025-1988
Published: 2025
Journal Articles

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets

Free
Shailaja Hegde, Huzoor Akbar, Ashley M. Wellendorf, Shawnagay Nestheide, James F. Johnson, Xueheng Zhao, Kenneth D. Setchell, Yi Zheng, Jose A. Cancelas
Journal: Blood
Blood (2024) 144 (16): 1732–1746.
https://doi.org/10.1182/blood.2023021453
Published: 2024
Includes: Supplemental data
Journal Articles

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate

Free
Mark J. Althoff, Ramesh C. Nayak, Shailaja Hegde, Ashley M. Wellendorf, Breanna Bohan, Marie-Dominique Filippi, Mei Xin, Q. Richard Lu, Hartmut Geiger, Yi Zheng, Maria T. Diaz-Meco, Jorge Moscat, Jose A. Cancelas
Journal: Blood
Blood (2020) 136 (16): 1824–1836.
https://doi.org/10.1182/blood.2019004113
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Scribble Controls HSC Self-Renewal through Polarity-Dependent Activation of the Hippo Signaling Pathway

Free
Mark J Althoff, BS, Ramesh C. Nayak, PhD, Shailaja Hegde, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 710.
https://doi.org/10.1182/blood.V130.Suppl_1.710.710
Published: 2017
Journal Articles

Δ 12 -prostaglandin J 3 , an omega-3 fatty acid–derived metabolite, selectively ablates leukemia stem cells in mice

Free
Shailaja Hegde, Naveen Kaushal, Kodihalli C. Ravindra, Christopher Chiaro, Kelsey T. Hafer, Ujjawal H. Gandhi, Jerry T. Thompson, John P. van den Heuvel, Mary J. Kennett, Pamela Hankey, Robert F. Paulson, K. Sandeep Prabhu
Journal: Blood
Blood (2011) 118 (26): 6909–6919.
https://doi.org/10.1182/blood-2010-11-317750
Published: 2011
Includes: Supplemental data
Journal Articles

Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signaling

Free
John M. Perry, Omid F. Harandi, Prashanth Porayette, Shailaja Hegde, Arun K. Kannan, Robert F. Paulson
Journal: Blood
Blood (2009) 113 (4): 911–918.
https://doi.org/10.1182/blood-2008-03-147892
Published: 2009
Includes: Supplemental data
Journal Articles

Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells

Free
Ke Li, Madhu P. Menon, Vinit G. Karur, Shailaja Hegde, Don M. Wojchowski
Journal: Blood
Blood (2003) 102 (9): 3147–3153.
https://doi.org/10.1182/blood-2003-01-0078
Published: 2003