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James F. Johnson
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Journal Articles

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets

Shailaja Hegde, Huzoor Akbar, Ashley M. Wellendorf, Shawnagay Nestheide, James F. Johnson, Xueheng Zhao, Kenneth D. Setchell, Yi Zheng, Jose A. Cancelas
Journal: Blood
Blood (2024) 144 (16): 1732–1746.
https://doi.org/10.1182/blood.2023021453
Published: 2024
Includes: Supplemental data
Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 99.
https://doi.org/10.1182/blood-2019-125359
Published: 2019
Journal Articles

Signaling and cytoskeletal requirements in erythroblast enucleation

Diamantis G. Konstantinidis, Suvarnamala Pushkaran, James F. Johnson, Jose A. Cancelas, Stefanos Manganaris, Chad E. Harris, David A. Williams, Yi Zheng, Theodosia A. Kalfa
Journal: Blood
Blood (2012) 119 (25): 6118–6127.
https://doi.org/10.1182/blood-2011-09-379263
Published: 2012
Journal Articles

Rational Targeting of the Signaling GTPase Cdc42 Establishes a Non-Myeloid Ablative Regimen for Hematopoietic Stem Cell Engraftment In Mouse Models

Wei Liu, M.D., M.S., Wei Du, MD, PhD, James F Johnson, BS, Qishen Pang, PhD, Yi Zheng, Ph.D.
Journal: Blood
Blood (2010) 116 (21): 73.
https://doi.org/10.1182/blood.V116.21.73.73
Published: 2010
Journal Articles

Rac1 targeting suppresses p53 deficiency–mediated lymphomagenesis

Emily E. Bosco, Wenjun Ni, Lei Wang, Fukun Guo, James F. Johnson, Yi Zheng
Journal: Blood
Blood (2010) 115 (16): 3320–3328.
https://doi.org/10.1182/blood-2009-02-202440
Published: 2010
Includes: Supplemental data
Journal Articles

A Novel Method of Mobilizing Leukemia Initiating Cells by a Small Molecule Cdc42 Activity-Specific Inhibitor (CASIN) for Acute Myeloid Leukemia Therapy.

Wei Liu, MD, MS, Benjamin Mizukawa, MD, Mark Wunderlich, MS, James F Johnson, James C. Mulloy, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2009) 114 (22): 13.
https://doi.org/10.1182/blood.V114.22.13.13
Published: 2009
Journal Articles

Rac1 GTPase Targeting Inhibits p53-Deficiency Mediated Lymphomagenesis.

Emily E Bosco, PhD, James F Johnson, Wenjun Ni, Yi Zheng, PhD
Journal: Blood
Blood (2008) 112 (11): 1764.
https://doi.org/10.1182/blood.V112.11.1764.1764
Published: 2008
Journal Articles

Rac GTPases Regulate Erythropoiesis Both in the Early Steps of Differentiation and in Enucleation.

Theodosia A. Kalfa, MD, PhD, Suvarnamala Pushkaran, Jose A. Cancelas, MD, PhD, James F. Johnson, Deidre Daria, Hartmut Geiger, PhD, David A. Williams, MD, Yi Zheng, PhD
Journal: Blood
Blood (2007) 110 (11): 1714.
https://doi.org/10.1182/blood.V110.11.1714.1714
Published: 2007
Journal Articles

Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton

Theodosia A. Kalfa, Suvarnamala Pushkaran, Narla Mohandas, John H. Hartwig, Velia M. Fowler, James F. Johnson, Clinton H. Joiner, David A. Williams, Yi Zheng
Journal: Blood
Blood (2006) 108 (12): 3637–3645.
https://doi.org/10.1182/blood-2006-03-005942
Published: 2006
Journal Articles

Deficiency of Rac1 and Rac2 GTPases Perturbs Erythroid Proliferation and Differentiation but Not Enucleation.

Theodosia A. Kalfa, MD,PhD, Suvarnamala Pushkaran, Jose A. Cancelas, MD, PhD, Michael Jansen, PhD, James F. Johnson, Kristen Hebel, David A. Williams, MD, Yi Zheng, PhD
Journal: Blood
Blood (2006) 108 (11): 467.
https://doi.org/10.1182/blood.V108.11.467.467
Published: 2006
Journal Articles

Rac2 GTPase Plays a Critical Role in Platelet Adhesion as Well as in Sustenance and Perpetuation of Platelet Aggregation.

Huzoor Akbar, PhD, James F. Johnson, David A. Williams, MD, Yi Zheng, PhD
Journal: Blood
Blood (2004) 104 (11): 3523.
https://doi.org/10.1182/blood.V104.11.3523.3523
Published: 2004
Journal Articles

Erythrocyte Cytoskeletal Defects Induced in Mice by Deletion of Rac GTPases.

Theodosia A. Kalfa, MD, PhD, Suvarnamala Pushkaran, James F. Johnson, Qian Wei, David A. Williams, MD, Yi Zheng, PhD
Journal: Blood
Blood (2004) 104 (11): 1573.
https://doi.org/10.1182/blood.V104.11.1573.1573
Published: 2004