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Journal Articles

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Hui Gai, MD, Rafa Gras~Pena, PhD, Yogendra Verma, MS, Vincent Fateh, BS, Kazuya Ikeda, MD, Beruh Dejene, MS, Dullei Min, Jing Wang, MD, Tomek Swigut, PhD, Ken I. Weinberg, MD, Georg A. Hollander, MD, Sarah Heilshorn, PhD, Maria-Grazia Roncarolo, MD, Vittorio Sebastiano, PhD, Katja G. Weinacht, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5092.
https://doi.org/10.1182/blood-2018-99-117499
Published: 2018
Journal Articles

GVHD clears the Aire in thymic selection

Mojibade N. Hassan, Edmund K. Waller
Journal: Blood
Blood (2015) 125 (17): 2593–2595.
https://doi.org/10.1182/blood-2015-03-630871
Published: 2015
Journal Articles

Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4 + T cells in acute GVHD

Brief Report
Simone Dertschnig, Mathias M. Hauri-Hohl, Madeleine Vollmer, Georg A. Holländer, Werner Krenger
Journal: Blood
Blood (2015) 125 (17): 2720–2723.
https://doi.org/10.1182/blood-2014-08-597245
Published: 2015
Includes: Supplemental data
Journal Articles

Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells

Jorieke H. Peters, Hans J. P. M. Koenen, Esther Fasse, Henk J. Tijssen, Jan N. M. IJzermans, Patricia J. T. A. Groenen, Nicolaas P. M. Schaap, Jaap Kwekkeboom, Irma Joosten
Journal: Blood
Blood (2013) 122 (13): 2213–2223.
https://doi.org/10.1182/blood-2013-03-489443
Published: 2013
Includes: Supplemental data
Journal Articles

Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD

Brief Report
Simone Dertschnig, Gretel Nusspaumer, Robert Ivanek, Mathias M. Hauri-Hohl, Georg A. Holländer, Werner Krenger
Journal: Blood
Blood (2013) 122 (5): 837–841.
https://doi.org/10.1182/blood-2012-12-474759
Published: 2013
Includes: Supplemental data
Journal Articles

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance

François-Xavier Hubert, Sarah A. Kinkel, Gayle M. Davey, Belinda Phipson, Scott N. Mueller, Adrian Liston, Anna I. Proietto, Ping Z. F. Cannon, Simon Forehan, Gordon K. Smyth, Li Wu, Christopher C. Goodnow, Francis R. Carbone, Hamish S. Scott, William R. Heath
Journal: Blood
Blood (2011) 118 (9): 2462–2472.
https://doi.org/10.1182/blood-2010-06-286393
Published: 2011
Includes: Supplemental data
Journal Articles

Hypomorphic Rag mutations can cause destructive midline granulomatous disease

Suk See De Ravin, Edward W. Cowen, Kol A. Zarember, Narda L. Whiting-Theobald, Douglas B. Kuhns, Netanya G. Sandler, Daniel C. Douek, Stefania Pittaluga, Pietro L. Poliani, Yu Nee Lee, Luigi D. Notarangelo, Lei Wang, Frederick W. Alt, Elizabeth M. Kang, Joshua D. Milner, Julie E. Niemela, Mary Fontana-Penn, Sara H. Sinal, Harry L. Malech
Journal: Blood
Blood (2010) 116 (8): 1263–1271.
https://doi.org/10.1182/blood-2010-02-267583
Published: 2010
Journal Articles

Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome

Brief Report
Pietro Luigi Poliani, Fabio Facchetti, Maria Ravanini, Andrew Richard Gennery, Anna Villa, Chaim M. Roifman, Luigi D. Notarangelo
Journal: Blood
Blood (2009) 114 (1): 105–108.
https://doi.org/10.1182/blood-2009-03-211029
Published: 2009
Includes: Supplemental data
Journal Articles

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes

Kai Kisand, Maire Link, Anette S. B. Wolff, Anthony Meager, Liina Tserel, Tõnis Org, Astrid Murumägi, Raivo Uibo, Nick Willcox, Katarina Trebušak Podkrajšek, Tadej Battelino, Anna Lobell, Olle Kämpe, Kari Lima, Antonella Meloni, Berrin Ergun-Longmire, Noel K. Maclaren, Jaakko Perheentupa, Kai J. E. Krohn, Hamish S. Scott, Eystein S. Husebye, Pärt Peterson
Journal: Blood
Blood (2008) 112 (7): 2657–2666.
https://doi.org/10.1182/blood-2008-03-144634
Published: 2008
Includes: Supplemental data
Journal Articles

Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma

Signe Hässler, Chris Ramsey, Mikael C. Karlsson, Disa Larsson, Björn Herrmann, Björn Rozell, Magnus Backheden, Leena Peltonen, Olle Kämpe, Ola Winqvist
Journal: Blood
Blood (2006) 108 (6): 1941–1948.
https://doi.org/10.1182/blood-2006-04-019679
Published: 2006
Includes: Supplemental data