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Frederick W. Alt
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Journal Articles

Elucidating Unifying Mechanisms for Inherited Predisposition to Childhood Acute Lymphoblastic Leukemia

Lara Wahlster, Anna-Lena Neehus, Andrew Lee, Alexis Caulier, Chen Weng, Susan Black, Jensen Pak, Jorge Diego Martin Rufino, Yiwen Zhang, Xiang Li, Travis Fleming, Mateusz Antoszewski, Sam Ha, Allison Zhang, Nicole Castano, Richard A Voit, Frederick W. Alt, Vijay G. Sankaran
Journal: Blood
Blood (2024) 144 (Supplement 1): 5709.
https://doi.org/10.1182/blood-2024-209255
Published: 2024
Journal Articles

Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency

Brief Report
Wenxia Jiang, Brian J. Lee, Chen Li, Richard L. Dubois, Monica Gostissa, Frederick W. Alt, Shan Zha
Journal: Blood
Blood (2015) 125 (17): 2665–2668.
https://doi.org/10.1182/blood-2015-01-622621
Published: 2015
Includes: Supplemental data
Journal Articles

Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function

Lisa S. Westerberg, Carin Dahlberg, Marisa Baptista, Christopher J. Moran, Cynthia Detre, Marton Keszei, Michelle A. Eston, Frederick W. Alt, Cox Terhorst, Luigi D. Notarangelo, Scott B. Snapper
Journal: Blood
Blood (2012) 119 (17): 3966–3974.
https://doi.org/10.1182/blood-2010-09-308197
Published: 2012
Includes: Supplemental data
Journal Articles

The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia

Brief Report
Alejandro Gutierrez, Alex Kentsis, Takaomi Sanda, Linda Holmfeldt, Shann-Ching Chen, Jianhua Zhang, Alexei Protopopov, Lynda Chin, Suzanne E. Dahlberg, Donna S. Neuberg, Lewis B. Silverman, Stuart S. Winter, Stephen P. Hunger, Stephen E. Sallan, Shan Zha, Frederick W. Alt, James R. Downing, Charles G. Mullighan, A. Thomas Look
Journal: Blood
Blood (2011) 118 (15): 4169–4173.
https://doi.org/10.1182/blood-2010-11-318873
Published: 2011
Includes: Supplemental data
Journal Articles

Hypomorphic Rag mutations can cause destructive midline granulomatous disease

Suk See De Ravin, Edward W. Cowen, Kol A. Zarember, Narda L. Whiting-Theobald, Douglas B. Kuhns, Netanya G. Sandler, Daniel C. Douek, Stefania Pittaluga, Pietro L. Poliani, Yu Nee Lee, Luigi D. Notarangelo, Lei Wang, Frederick W. Alt, Elizabeth M. Kang, Joshua D. Milner, Julie E. Niemela, Mary Fontana-Penn, Sara H. Sinal, Harry L. Malech
Journal: Blood
Blood (2010) 116 (8): 1263–1271.
https://doi.org/10.1182/blood-2010-02-267583
Published: 2010
Journal Articles

Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation

William Giblin, Monalisa Chatterji, Gerwin Westfield, Tehmina Masud, Brian Theisen, Hwei-Ling Cheng, Jeffrey DeVido, Frederick W. Alt, David O. Ferguson, David G. Schatz, JoAnn Sekiguchi
Journal: Blood
Blood (2009) 113 (13): 2965–2975.
https://doi.org/10.1182/blood-2008-07-165167
Published: 2009
Includes: Supplemental data
Journal Articles

Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations

Craig H. Bassing, Sheila Ranganath, Mike Murphy, Velibor Savic, Meagan Gleason, Frederick W. Alt
Journal: Blood
Blood (2008) 111 (4): 2163–2169.
https://doi.org/10.1182/blood-2007-08-104760
Published: 2008
Includes: Supplemental data
Journal Articles

Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation

Rhine R. Shen, David O. Ferguson, Mathilde Renard, Katrina K. Hoyer, Unkyu Kim, Xingpei Hao, Frederick W. Alt, Robert G. Roeder, Herbert C. Morse, III, Michael A. Teitell
Journal: Blood
Blood (2006) 108 (6): 1991–1998.
https://doi.org/10.1182/blood-2006-02-001354
Published: 2006
Includes: Supplemental data
Journal Articles

Activating Notch1 mutations in mouse models of T-ALL

Brief Report
Jennifer O'Neil, Jennifer Calvo, Keith McKenna, Veena Krishnamoorthy, Jon C. Aster, Craig H. Bassing, Frederick W. Alt, Michelle Kelliher, A. Thomas Look
Journal: Blood
Blood (2006) 107 (2): 781–785.
https://doi.org/10.1182/blood-2005-06-2553
Published: 2006
Includes: Supplemental data
Journal Articles

Activating Notch1 Mutations in Mouse Models of T-ALL.

Jennifer O’Neil, PhD, Jennifer Calvo, Keith McKenna, Veena Krishnamoorthy, Jon C. Aster, MD, PhD, Craig H. Bassing, PhD, Frederick W. Alt, PhD, Michelle Kelliher, PhD, A. Thomas Look, MD
Journal: Blood
Blood (2005) 106 (11): 2609.
https://doi.org/10.1182/blood.V106.11.2609.2609
Published: 2005