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David G. Schatz
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Journal Articles

Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1 -dependent immune deficiencies

Patrick M. Brauer, Itai M. Pessach, Erik Clarke, Jared H. Rowe, Lisa Ott de Bruin, Yu Nee Lee, Carmen Dominguez-Brauer, Anne M. Comeau, Geneve Awong, Kerstin Felgentreff, Yuhang H. Zhang, Andrea Bredemeyer, Waleed Al-Herz, Likun Du, Francesca Ververs, Marion Kennedy, Silvia Giliani, Gordon Keller, Barry P. Sleckman, David G. Schatz, Frederic D. Bushman, Luigi D. Notarangelo, Juan Carlos Zúñiga-Pflücker
Journal: Blood
Blood (2016) 128 (6): 783–793.
https://doi.org/10.1182/blood-2015-10-676304
Published: 2016
Includes: Supplemental data
Journal Articles

Mechanisms of Clonal Evolution of Pre-Leukemic Clones in Childhood Pre-B Acute Lymphoblastic Leukemia

Srividya Swaminathan, PhD, Lars Klemm, Eugene Park, Anthony M Ford, PhD, Soo-mi Kweon, PhD, Daniel Trageser, Brian Hasselfeld, Nadine Henke, Huimin Geng, PhD, Klaus Schwarz, MD, Rafael Casellas, David G. Schatz, PhD, Michael R Lieber, MD PhD, Elli Papaemmanuil, PhD, Mel Greaves, PhD, Markus Muschen, MD PhD
Journal: Blood
Blood (2014) 124 (21): 861.
https://doi.org/10.1182/blood.V124.21.861.861
Published: 2014
Journal Articles

Protecting the Genome: Mechanisms Targeting Somatic Hypermutation

David G. Schatz, PhD, Jean-Marie Buerstedde, Jukka Alinikula, Jessica McDonald, Kristen Kohler, Hiroshi Arakawa
Journal: Blood
Blood (2013) 122 (21): SCI-13.
https://doi.org/10.1182/blood.V122.21.SCI-13.SCI-13
Published: 2013
Journal Articles

Cooperation Between Aid and the Rag1/Rag2 V(D)J Recombinase Drives Clonal Evolution of Childhood Acute Lymphoblastic Leukemia

Srividya Swaminathan, B Tech, Lars Klemm, MSc, Anthony M. Ford, PhD, Klaus Schwarz, MD, Rafael Casellas, Lothar Hennighausen, Huimin Geng, PhD, David G. Schatz, Michael R. Lieber, MD, PhD, Mel Greaves, MD, PhD, Markus Muschen, MD
Journal: Blood
Blood (2012) 120 (21): 519.
https://doi.org/10.1182/blood.V120.21.519.519
Published: 2012
Journal Articles

Dendritic cell–mediated activation-induced cytidine deaminase (AID)–dependent induction of genomic instability in human myeloma

Srinivas Koduru, Ellice Wong, Till Strowig, Ranjini Sundaram, Lin Zhang, Matthew P. Strout, Richard A. Flavell, David G. Schatz, Kavita M. Dhodapkar, Madhav V. Dhodapkar
Journal: Blood
Blood (2012) 119 (10): 2302–2309.
https://doi.org/10.1182/blood-2011-08-376236
Published: 2012
Journal Articles

The Role of DNA Repair in the Pathogenesis of Activation Induced Cytidine Deaminase Dependent B Cell Lymphoma

Xiwen Gu, Ph.D., Carmen J. Booth, D.V.M., Ph.D., David G. Schatz, Ph.D., Matthew P. Strout, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 397.
https://doi.org/10.1182/blood.V118.21.397.397
Published: 2011
Journal Articles

Regulation of the Mutation Threshold During Immune Diversification by Activation Induced Cytidine Deaminase,

Matthew P. Strout, M.D., Ph.D., Naomi Philip, David G. Schatz, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3244.
https://doi.org/10.1182/blood.V118.21.3244.3244
Published: 2011
Journal Articles

Infectious Origins of Childhood Leukemia

Lars Klemm, Srividya Swaminathan, Anthony M Ford, Klaus Schwarz, MD, David G. Schatz, Ph.D., Michael R. Lieber, MD, PhD, Melvin F Greaves, Markus Muschen
Journal: Blood
Blood (2011) 118 (21): 751.
https://doi.org/10.1182/blood.V118.21.751.751
Published: 2011
Journal Articles

IL7Rα Signaling Prevents Premature Expression of AID In Human Pre-B Cells: Implications for Clonal Evolution of Childhood Leukemia

Srividya Swaminathan, Lars Klemm, Soo-mi Kweon, Anthony Ford, Klaus Schwarz, Rafael Casellas, Lothar Hennighausen, David G. Schatz, Michael R. Lieber, Mel F. Greaves, Markus Muschen
Journal: Blood
Blood (2010) 116 (21): 26.
https://doi.org/10.1182/blood.V116.21.26.26
Published: 2010
Journal Articles

Negative Regulation of Activation-Induced Cytidine Deaminase Protein Prevents Aberrant Somatic Hypermutation and Lymphomagenesis.

Matthew P. Strout, M.D., Ph.D., David G. Schatz, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 94.
https://doi.org/10.1182/blood.V114.22.94.94
Published: 2009
Journal Articles

Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation

William Giblin, Monalisa Chatterji, Gerwin Westfield, Tehmina Masud, Brian Theisen, Hwei-Ling Cheng, Jeffrey DeVido, Frederick W. Alt, David O. Ferguson, David G. Schatz, JoAnn Sekiguchi
Journal: Blood
Blood (2009) 113 (13): 2965–2975.
https://doi.org/10.1182/blood-2008-07-165167
Published: 2009
Includes: Supplemental data
Journal Articles

A Role for Small RNA Molecules during the DNA Repair Phase of Somatic Hypermutation

Matthew P. Strout, M.D., Ph.D., David G. Schatz, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 785.
https://doi.org/10.1182/blood.V112.11.785.785
Published: 2008