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Journal Articles

Interaction of Plasmacytoid Dendritic Cells and Myeloma Cells Trigger Tumor Promoting Transcriptional Changes in Multiple Myeloma Cells

Arghya Ray, PhD, Leutz Buon, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 510.

https://doi.org/10.1182/blood-2019-123333

Published: 2019

Journal Articles

Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

Sophia Adamia, PhD, Daisuke Ogiya, MD PhD, Ivane Abiatari, MD, Sigitas J Verselis, PhD, Michael P. Chu, David M. Dorfman, MD PhD, Linda M. Pilarski, PhD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 3079.

https://doi.org/10.1182/blood-2019-131243

Published: 2019

Journal Articles

Blockade of Ubiquitin Receptor Rpn13 in Plasmacytoid Dendritic Cells Enhances Anti-Myeloma Immunity

Arghya Ray, PhD, Yan Song, PhD, Ting DU, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 3098.

https://doi.org/10.1182/blood-2019-122901

Published: 2019

Journal Articles

Preclinical Validation of Alpha-Enolase (ENO1) As a Novel Immunometabolic Target in Multiple Myeloma

Arghya Ray, PhD, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 856.

https://doi.org/10.1182/blood-2019-123328

Published: 2019

Journal Articles

Development of Novel Second Generation DC/Tumor Fusion Vaccine in Lymphoma

Shira Orr, PhD, Marzia Capelletti, PhD MBBS, Haider Ghiasuddin, Dina Stroopinsky, PhD, Jessica Liegel, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Adam Morin, Robin M. Joyce, MD, Salvia Jain, MD, Jon E. Arnason, MD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD

Blood (2019) 134 (Supplement_1): 392.

https://doi.org/10.1182/blood-2019-124768

Published: 2019

Journal Articles

Bispecific T-Cell Engager (BiTE) Antibody Based Immunotherapy for Treatment of Relapsed Refractory Multiple Myeloma (RRMM): A Systematic Review of Preclinical and Clinical Trials

Zunairah Shah, MBBS, Mustafa Nadeem Malik, MD, Syeda Sabeeka Batool, MBBS, MD, Sravanthi Kotapati, MBBS, Aisha Akhtar, MBBS, Owais ur Rehman, MBBS, Marium Ghani, MBBS, Maryam Sadiq, MBBS, Arshia Akbar, MD, Aqsa Ashraf, MBBS, Arafat Ali Ali Farooqui, MD, Muhammad Abdullah Yousaf, MBBS, MD, Muhaddis Ejaz Ahmad, MD, Hafiz Muhammad Fazeel, MBBS, Faiz Anwer, MD

Blood (2019) 134 (Supplement_1): 5567.

https://doi.org/10.1182/blood-2019-129652

Published: 2019

Journal Articles

Identification and Isolation of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients through the Identification of T-Cells Capable to Establish Stable Interactions with Leukemic Cells

Estefania Garcia-Guerrero, Luis I. Sanchez-Abarca, PhD, Esther Domingo, PhD, Teresa Ramos, PhD, Jose Antonio Bejarano-García, Jose A Gonzalez-Campos, MD, Teresa Caballero-Velázquez, MD PhD, José A. Pérez-Simón, MD PhD

Blood (2018) 132 (Supplement 1): 3336.

https://doi.org/10.1182/blood-2018-99-118118

Published: 2018

Journal Articles

First-in-Human, Multicenter Phase I Study of IPH4102, First-in-Class Humanized Anti-KIR3DL2 Monoclonal Antibody, in Relapsed/Refractory Cutaneous T-Cell Lymphomas: Preliminary Safety, Exploratory and Clinical Activity Results

Blood (2016) 128 (22): 1826.

https://doi.org/10.1182/blood.V128.22.1826.1826

Published: 2016

Journal Articles

Potential for Dendritic Cell Stimulated De Novo Anti-Leukaemia CD4 T Cell Response in the Bone Marrow Tumour Microenvironment during Induction Chemotherapy

Kate L E Phillips, PhD, Joanne E Dean, BSc, Brian F Flanagan, PhD, Steve E Christmas, DPhil, Russell D Keenan, MB ChB, PhD FRCP, FRCPath

Blood (2016) 128 (22): 2524.

https://doi.org/10.1182/blood.V128.22.2524.2524

Published: 2016

Journal Articles

A Novel Dendritic Cell-Derived Vaccine in Multiple Myeloma

Rebecca Karp Leaf, MD, Dina Stroopinsky, PhD, Athalia Rachel Pyzer, MD, Ada M. Kruisbeek, PhD, Sandra Van Wetering, PhD, Abigail J. Washington, BA, Leandra Cole, BA, Myrna R. Nahas, MD, Salvia Jain, MD, Arie Apel, MD, Jon Arnason, MD, Ayad Hamdan, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD

Blood (2016) 128 (22): 4484.

https://doi.org/10.1182/blood.V128.22.4484.4484

Published: 2016

Journal Articles

Blockade of PD-1 in Combination with Dendritic Cell/Myeloma Fusion Cell Vaccination Following Autologous Stem Cell Transplantation Is Well Tolerated, Induces Anti-Tumor Immunity and May Lead to Eradication of Measureable Disease

Blood (2015) 126 (23): 4218.

https://doi.org/10.1182/blood.V126.23.4218.4218

Published: 2015

Journal Articles

Concomitant Administration of Gene-Modified T Cells Expressing a Chimeric CD16-CD3ζ Receptor with Mogamulizmab Synergistically Suppresses Adult T Cell Leukemia Cells in Vivo

Kazushi Tanimoto, MD PhD, Hiroshi Fujiwara, MD PhD, Hiroki Tanaka, MD, Fumihiro Ochi, MD, Hiroaki Asai, MDPhD, Sachiko Okamoto, PhD, Junichi Mineno, PhD, Kiyotaka Kuzushima, MD PhD, Hiroshi Shiku, MD PhD, John Barrett, MD, Masaki Yasukawa, MD PhD

Blood (2014) 124 (21): 307.

https://doi.org/10.1182/blood.V124.21.307.307

Published: 2014

Journal Articles

Seven Year Followup for Bystander Vaccine Therapy in Mantle Cell Lymphoma (MCL)

Bijal D. Shah, MD, Jianguo Tao, MD PhD, Paul A. Chervenick, MD, Marcie L Riches, MD MS, Javier Pinilla-Ibarz, MD PhD, Lynn C. Moscinski, MD, Scott Antonia, MD, Eduardo M. Sotomayor, MD, Sophie Dessureault, MD

Blood (2014) 124 (21): 3083.

https://doi.org/10.1182/blood.V124.21.3083.3083

Published: 2014

Journal Articles

Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma

Holbrook E Kohrt, MD PhD, Jaqueline Chu, MD, Joshua Brody, MD, Debra K Czerwinski, Cariad Chester, Mohith Sadaram, BS, Ranjana Advani, MD, Youn H. Kim, MD, Richard T. Hoppe, MD, Susan J. Knox, MD PhD, Irene Wapnir, MD, Robert J. Tibshirani, PhD, Ron Levy, MD

Blood (2014) 124 (21): 3092.

https://doi.org/10.1182/blood.V124.21.3092.3092

Published: 2014

Journal Articles

Enhancing Natural Killer Cell-Mediated Lysis of Lymphoma Cells By Combining Therapeutic Antibodies with CD20-Specific Immunoligands Engaging NKG2D or NKp30

Matthias Peipp, PhD, Christian Kellner, PhD, Andreas Günther, MD, Andreas Humpe, MD, Roland Repp, MD, Katja Klausz, PhD, Stefanie Derer, PhD, Thomas Valerius, MD, Jan G.J. van de Winkel, PhD, Paul W.H.I. Parren, PhD, Martin Gramatzki, MD

Blood (2014) 124 (21): 1779.

https://doi.org/10.1182/blood.V124.21.1779.1779

Published: 2014

Journal Articles

TLR7 Ligand Potentiates GM-CSF-Initiated Antitumor Immunity Through Activation Of Plasmacytoid Dendritic Cells

Megumi Narusawa, Hiroyuki Inoue, MD, PhD, Chika Sakamoto, Yumiko Matsumura, DVM PhD, Atsushi Takahashi, MD, PhD, Ayumi Watanabe, Tomoko Inoue, PhD, Shohei Miyamoto, Koichi Takayama, MD, PhD, Makoto Inoue, PhD, Mamoru Hasegawa, PhD, Yoichi Nakanishi, MD, PhD, Kenzaburo Tani, MD, PhD

Blood (2013) 122 (21): 4491.

https://doi.org/10.1182/blood.V122.21.4491.4491

Published: 2013

Journal Articles

Preclinical Evaluation Of Engineered T Cells In Multiple Myeloma: Uncovering a Mechanism Of Immune Escape

Zandra K. Klippel, MD, Jeffrey Chou, MD, PhD, Andrea M. H. Towlerton, Paul F Robbins, PhD, Lilien Voong, William I. Bensinger, MD, H. Lokhorst, Tuna Mutis, MD, PhD, Lihua Elizabeth Budde, MD, PhD, Edus H. Warren, III, MD, PhD

Blood (2013) 122 (21): 4205.

https://doi.org/10.1182/blood.V122.21.4205.4205

Published: 2013

Journal Articles

Autologous Whole Tumor Cell Vaccination Early After Allogeneic Stem Cell Transplantation Elicits Anti-Tumor T Cell Responses in Patients with Advanced Chronic Lymphocytic Leukemia (CLL)

Blood (2012) 120 (21): 1892.

https://doi.org/10.1182/blood.V120.21.1892.1892

Published: 2012

Journal Articles

Human Multiple Myeloma and Breast Cancer Cells Evade Immune Rejection Through Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6.

Mathias Witzens-Harig, MD, Dirk Hose, MD, PhD, Simone Jünger, Christina Pfirschke, Nisit Khandelwal, Anja Seckinger, MD, Heinke Conrad, Bettina Brackertz, Thierry Reme, Brigittte Gückel, Tobias Meissner, Michael Hundemer, Anthony D Ho, MD, Jean-Francois Rossi, MD, PhD, Kai Neben, MD, Helga Bernhard, MD, Hartmut Goldschmidt, MD, Bernard Klein, Philipp Beckhove

Blood (2012) 120 (21): 2942.

https://doi.org/10.1182/blood.V120.21.2942.2942

Published: 2012

Journal Articles

TCL1: a shared tumor-associated antigen for immunotherapy against B-cell lymphomas

Jinsheng Weng, Seema Rawal, Fuliang Chu, Hyun Jun Park, Rakesh Sharma, David A. Delgado, Luis Fayad, Michelle Fanale, Jorge Romaguera, Amber Luong, Larry W. Kwak, Sattva S. Neelapu

Blood (2012) 120 (8): 1613–1623.

https://doi.org/10.1182/blood-2011-09-382838

Published: 2012

Includes: Supplemental data

NARROW

Interaction of Plasmacytoid Dendritic Cells and Myeloma Cells Trigger Tumor Promoting Transcriptional Changes in Multiple Myeloma Cells

Altered Genomic and Epigenetic Profiling of Myeloma Bone Marrow Stromal Cells Identifies Targets for Current and Future Immunotherapeutic Approaches

Blockade of Ubiquitin Receptor Rpn13 in Plasmacytoid Dendritic Cells Enhances Anti-Myeloma Immunity

Preclinical Validation of Alpha-Enolase (ENO1) As a Novel Immunometabolic Target in Multiple Myeloma

Development of Novel Second Generation DC/Tumor Fusion Vaccine in Lymphoma

Bispecific T-Cell Engager (BiTE) Antibody Based Immunotherapy for Treatment of Relapsed Refractory Multiple Myeloma (RRMM): A Systematic Review of Preclinical and Clinical Trials

Identification and Isolation of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients through the Identification of T-Cells Capable to Establish Stable Interactions with Leukemic Cells

First-in-Human, Multicenter Phase I Study of IPH4102, First-in-Class Humanized Anti-KIR3DL2 Monoclonal Antibody, in Relapsed/Refractory Cutaneous T-Cell Lymphomas: Preliminary Safety, Exploratory and Clinical Activity Results

Potential for Dendritic Cell Stimulated De Novo Anti-Leukaemia CD4 T Cell Response in the Bone Marrow Tumour Microenvironment during Induction Chemotherapy

A Novel Dendritic Cell-Derived Vaccine in Multiple Myeloma

Blockade of PD-1 in Combination with Dendritic Cell/Myeloma Fusion Cell Vaccination Following Autologous Stem Cell Transplantation Is Well Tolerated, Induces Anti-Tumor Immunity and May Lead to Eradication of Measureable Disease

Concomitant Administration of Gene-Modified T Cells Expressing a Chimeric CD16-CD3ζ Receptor with Mogamulizmab Synergistically Suppresses Adult T Cell Leukemia Cells in Vivo

Seven Year Followup for Bystander Vaccine Therapy in Mantle Cell Lymphoma (MCL)

Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma

Enhancing Natural Killer Cell-Mediated Lysis of Lymphoma Cells By Combining Therapeutic Antibodies with CD20-Specific Immunoligands Engaging NKG2D or NKp30

TLR7 Ligand Potentiates GM-CSF-Initiated Antitumor Immunity Through Activation Of Plasmacytoid Dendritic Cells

Preclinical Evaluation Of Engineered T Cells In Multiple Myeloma: Uncovering a Mechanism Of Immune Escape

Autologous Whole Tumor Cell Vaccination Early After Allogeneic Stem Cell Transplantation Elicits Anti-Tumor T Cell Responses in Patients with Advanced Chronic Lymphocytic Leukemia (CLL)

Human Multiple Myeloma and Breast Cancer Cells Evade Immune Rejection Through Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6.

TCL1: a shared tumor-associated antigen for immunotherapy against B-cell lymphomas

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