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Journal Articles

NEK2 Promotes Bortezomib Resistance through Enhancing Autophagy By Upregulation of Beclin1 in Multiple Myeloma Cells

Jiliang Xia, PhD, Yanjuan He, MD, Bin Meng, Jingyu Zhang, Xuan Wu, Xiangling Feng, PhD, Chunmei Kuang, Jiaojiao Guo, Yinghong Zhu, Qian Lei, Yongjun Guan, Yi Shen, MD PhD, Lugui Qiu, MD PhD, Wen Zhou, PhD

Blood (2019) 134 (Supplement_1): 4332.

https://doi.org/10.1182/blood-2019-126617

Published: 2019

Journal Articles

Autophagy in Endothelial Cells Regulates Their Hematopoiesis Supporting Ability

Yuan Kong, MD PhD, Xie-Na Cao, Zhong-Shi Lyu, PhD, Xiao-Dong Mo, Qi Wen, MD, Hong-Yan Zhao, MD, Yu-Hong Chen, Yu Wang, Ying-Jun Chang, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang

Blood (2019) 134 (Supplement_1): 4425.

https://doi.org/10.1182/blood-2019-122227

Published: 2019

Journal Articles

Inhibition of TLR4 Signaling Affects Mitochondrial Fitness Overcoming Bortezomib Resistance in Myeloma Plasma Cells

Cesarina Giallongo, PhD, Daniele Tibullo, PhD, Giuseppina Camiolo, Fabrizio Puglisi, Daniela Cambria, Alessandro Barbato, Nunziatina Laura Parrinello, PhD, Alessandra Romano, MD PhD, Concetta Conticello, MD, Angela Amorini, PhD, Giovanni Li Volti, MD PhD, Giuseppe Lazzarino, Giuseppe A. Palumbo, MD PhD, Francesco Di Raimondo, MD

Blood (2019) 134 (Supplement_1): 3073.

https://doi.org/10.1182/blood-2019-129812

Published: 2019

Journal Articles

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Wulin Aerbajinai, MD PhD, Jianqiong Zhu, MD, Chutima Kumkhaek, PhD, Kyung Chin, Griffin Rodgers, MD

Blood (2019) 134 (Supplement_1): 2318.

https://doi.org/10.1182/blood-2019-130318

Published: 2019

Journal Articles

Hexokinase-2 Regulates Hypoxia-Inducible Autophagy, Leading to Enhance Anti-Apoptotic Capability of Refractory Multiple Myeloma

Sho Ikeda, MD PhD, Fumito Abe, MD PhD, Matsuda Yuka, Akihiro Kitadate, MD PhD, Takahiro Kobayashi, MD PhD, Naoto Takahashi, MD PhD, Hiroyuki Tagawa, MD PhD

Blood (2019) 134 (Supplement_1): 1787.

https://doi.org/10.1182/blood-2019-123360

Published: 2019

Journal Articles

Oxphos Inhibition Induces Formation of Tunneling Nanotubes in AML Cells and Facilitates Mitochondrial Transfer from BM Stroma to AML That Contributes to Microenvironment-Mediated Drug-Resistance of AML

Blood (2019) 134 (Supplement_1): 911.

https://doi.org/10.1182/blood-2019-125007

Published: 2019

Journal Articles

ATG5 Dependent Autophagy in Graft-Versus-Host Disease Target Organs Mitigates Disease Severity Post Allogeneic Bone Marrow Transplant

Austin Taylor, BA, Kay Oravecz-Wilson, Hideaki Fujiwara, Stephanie Kim, Dan Peltier, Molly Radosevich, Yaping Sun, Pavan Reddy

Blood (2019) 134 (Supplement_1): 1914.

https://doi.org/10.1182/blood-2019-131879

Published: 2019

Journal Articles

Emerging Mechanisms of Cellular Iron Transport and Trafficking

Caroline Philpott, Moon-Suhn Ryu, PhD

Blood (2018) 132 (Supplement 1): SCI-2.

https://doi.org/10.1182/blood-2018-99-109519

Published: 2018

Journal Articles

Chloroquine Derivative Lys05 Overcomes Hypoxia-Induced Chemoresistance in Acute Myeloid Leukemia through Metabolic Disruption

Matthew Johnson, Kaitlyn Dykstra, PhD, Tara Cronin, BA, Linda Lutgen-Dunckley, Brandon L Martens, BS, Monica L. Guzman, PhD, Eunice S. Wang, MD

Blood (2018) 132 (Supplement 1): 3948.

https://doi.org/10.1182/blood-2018-99-116961

Published: 2018

Journal Articles

Inhibiting the Core Autophagy Enzyme ATG4B with Novel Drugs Sensitizes Resistant Leukemic Stem/Progenitor Cells to Standard Targeted Therapy

Katharina Rothe, PhD, Akie Watanabe, Donna L. Forrest, MD, Sharon Gorski, PhD, Robert Young, PhD, Xiaoyan Jiang, MDPhD

Blood (2018) 132 (Supplement 1): 933.

https://doi.org/10.1182/blood-2018-99-117309

Published: 2018

Journal Articles

Inhibition of Unc-51-like Kinase 1 (ULK1) with Novel Small Molecular Inhibitor MRT68921 Preferentially Induces Apoptosis and Autophagy in FLT3-ITD- Mutated Acute Myeloid Leukemia

Jieun Jang, MD, Hoi-kyung Jeung, So-Young Seol, Haerim Chung, MD, Yu Ri Kim, MD, June-Won Cheong, MD PhD, Yoo Hong Min, MD PhD

Blood (2018) 132 (Supplement 1): 3499.

https://doi.org/10.1182/blood-2018-99-115833

Published: 2018

Journal Articles

Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/RarÎ± Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: In Vitro and In Vivo studies

Dijiong Wu, Keding Shao, MD, Qihao Zhou, MD, Jie Sun, Ziqi Wang, Fei Yan, Tingting Liu, Xiangping Wu, Baodong Ye, He Huang, MD PhD, Yuhong Zhou

Blood (2018) 132 (Supplement 1): 2646.

https://doi.org/10.1182/blood-2018-99-115699

Published: 2018

Journal Articles

Arginine Depletion in Combination with Canavanine Supplementation Induces Massive Cell Death in Myeloma Cells By Interfering with Their Protein Metabolism and Bypassing Potential Rescue Mechanisms

Johannes Windschmitt, Björn Jacobi, MD, Yagmur Bülbül, Lilli Sester, Janine Tappe, Christof Hiebel, PhD, Christian Behl, PhD, Matthias Theobald, Markus Munder, MD

Blood (2018) 132 (Supplement 1): 3205.

https://doi.org/10.1182/blood-2018-99-113396

Published: 2018

Journal Articles

Chronic Lymphocytic Leukaemia Relies on Lipid Scavenging and Synthesis As an Energy Source

Lauren A Thurgood, PhD, Lara Escane, BMedSci, BSci (Hons), Christie A Bader, BSci (Hons), PhD, Karen M Lower, BSc (Hons), PhD GradCertEd (HighEd), Doug A Brooks, BSci, BSci (Hons), PhD, Bryone J. Kuss, PhD, BMBS, FRCPA, FRACP

Blood (2018) 132 (Supplement 1): 3117.

https://doi.org/10.1182/blood-2018-99-120241

Published: 2018

Journal Articles

Resistance to Nutrient Deprivation Via Metabolic Re-Programming As Mechanism of 'Metastasis' Promotion in Multiple Myeloma

Ioanna Savvidou, MD, Sahan Chandrasekara, MD, Maoshan Chenn, PhD, Tiffany Khong, BSc, PhD, Andrew Spencer, MBBS, FRACP, FRCPA, DM

Blood (2018) 132 (Supplement 1): 3218.

https://doi.org/10.1182/blood-2018-99-112802

Published: 2018

Journal Articles

IL-7 Either Promotes or Inhibits Autophagy, Depending on the Stress Context, to Promote the Viability of T-Cell Acute Lymphoblastic Leukemia Cells

Daniel Ribeiro, PhD, Inês Lopes, Marta Abreu, Carlos Custódia, MSc, Joao Barata, PhD

Blood (2018) 132 (Supplement 1): 2822.

https://doi.org/10.1182/blood-2018-99-119037

Published: 2018

Journal Articles

Development of Inhibitors of PIP4K2 As a Treatment for Patients with Hematologic Malignancies

Blood (2018) 132 (Supplement 1): 213.

https://doi.org/10.1182/blood-2018-99-118355

Published: 2018

Journal Articles

Altered Transcriptome Uniquely Associated with AML Vs. Normal Hematopoiesis

Yu Fan, Ying Hu, Cu Nguyen, Chunhua Yan, Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jenny L. Smith, MSc, MD, Qingrong Chen, E. Anders Kolb, MD, Soheil Meshinchi, MD PhD, Daoud Meerzaman

Blood (2017) 130 (Supplement 1): 3792.

https://doi.org/10.1182/blood.V130.Suppl_1.3792.3792

Published: 2017

Journal Articles

Activation of Autophagy in Models of SF3B1 Mutant MDS

Blood (2017) 130 (Supplement 1): 4230.

https://doi.org/10.1182/blood.V130.Suppl_1.4230.4230

Published: 2017

Journal Articles

Inhibition of p62-ZZ Domain-Mediated Signaling Overcomes Bortezomib Resistance in Multiple Myeloma Cells Independent of Their p53 Status

Silvia Marino, PhD, Daniela Nicoleta Petrusca, PhD, Rebecca Silberman, MD, Denise Toscani, PhD, Judith L Anderson, Nicola Giuliani, MD PhD, Xiang-Qun Xie, PhD, Noriyoshi Kurihara, DDS, PhD, G David Roodman, MD PhD

Blood (2017) 130 (Supplement 1): 4421.

https://doi.org/10.1182/blood.V130.Suppl_1.4421.4421

Published: 2017

NARROW

NEK2 Promotes Bortezomib Resistance through Enhancing Autophagy By Upregulation of Beclin1 in Multiple Myeloma Cells

Autophagy in Endothelial Cells Regulates Their Hematopoiesis Supporting Ability

Inhibition of TLR4 Signaling Affects Mitochondrial Fitness Overcoming Bortezomib Resistance in Myeloma Plasma Cells

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Hexokinase-2 Regulates Hypoxia-Inducible Autophagy, Leading to Enhance Anti-Apoptotic Capability of Refractory Multiple Myeloma

Oxphos Inhibition Induces Formation of Tunneling Nanotubes in AML Cells and Facilitates Mitochondrial Transfer from BM Stroma to AML That Contributes to Microenvironment-Mediated Drug-Resistance of AML

ATG5 Dependent Autophagy in Graft-Versus-Host Disease Target Organs Mitigates Disease Severity Post Allogeneic Bone Marrow Transplant

Emerging Mechanisms of Cellular Iron Transport and Trafficking

Chloroquine Derivative Lys05 Overcomes Hypoxia-Induced Chemoresistance in Acute Myeloid Leukemia through Metabolic Disruption

Inhibiting the Core Autophagy Enzyme ATG4B with Novel Drugs Sensitizes Resistant Leukemic Stem/Progenitor Cells to Standard Targeted Therapy

Inhibition of Unc-51-like Kinase 1 (ULK1) with Novel Small Molecular Inhibitor MRT68921 Preferentially Induces Apoptosis and Autophagy in FLT3-ITD- Mutated Acute Myeloid Leukemia

Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/RarÎ± Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: In Vitro and In Vivo studies

Arginine Depletion in Combination with Canavanine Supplementation Induces Massive Cell Death in Myeloma Cells By Interfering with Their Protein Metabolism and Bypassing Potential Rescue Mechanisms

Chronic Lymphocytic Leukaemia Relies on Lipid Scavenging and Synthesis As an Energy Source

Resistance to Nutrient Deprivation Via Metabolic Re-Programming As Mechanism of 'Metastasis' Promotion in Multiple Myeloma

IL-7 Either Promotes or Inhibits Autophagy, Depending on the Stress Context, to Promote the Viability of T-Cell Acute Lymphoblastic Leukemia Cells

Development of Inhibitors of PIP4K2 As a Treatment for Patients with Hematologic Malignancies

Altered Transcriptome Uniquely Associated with AML Vs. Normal Hematopoiesis

Activation of Autophagy in Models of SF3B1 Mutant MDS

Inhibition of p62-ZZ Domain-Mediated Signaling Overcomes Bortezomib Resistance in Multiple Myeloma Cells Independent of Their p53 Status

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American Society of Hematology

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ASH Publications

American Society of Hematology

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