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Journal Articles

Antitumor immunity and T-cell avidity

Peter Brossart

Blood (2020) 136 (4): 378–380.

https://doi.org/10.1182/blood.2020006562

Published: 2020

Journal Articles

A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity

Marthe C. J. Roex, Lois Hageman, Sabrina A. J. Veld, Esther van Egmond, Conny Hoogstraten, Christian Stemberger, Lothar Germeroth, Hermann Einsele, J. H. Frederik Falkenburg, Inge Jedema

Blood (2020) 136 (4): 455–467.

https://doi.org/10.1182/blood.2019004443

Published: 2020

Includes: Supplemental data

Journal Articles

Gastrointestinal (GI) Involvement with Non-Hodgkin's Lymphoma (NHL) Impacts Outcome; A Retrospective Single Tertiary Care Center Analysis of Clinico-Pathologic Characteristics Provides an Alternate Insight to Presentation and Outcome

Ghada Zakout, FRCPATH, MRCP (UK), MBBCh (Hon), Charalampia Kyriakou

Blood (2019) 134 (Supplement_1): 5246.

https://doi.org/10.1182/blood-2019-127152

Published: 2019

Journal Articles

Elispots and Ex Vivo Expansion of FVIII-Specific T-Cell Clones Confirm Specificity of CD4 + T-Cell Responses to Self-FVIII in Healthy Non-Hemophilic Blood Donors

Ahmad Faisal Karim, PhD, Pooja Vir, PhD, Devi Gunasekera, MBBS, Allen I. Stering, MD, Kenneth Lieuw, MD PhD, Kathleen P. Pratt, PhD

Blood (2019) 134 (Supplement_1): 2413.

https://doi.org/10.1182/blood-2019-124803

Published: 2019

Journal Articles

High Avidity IgM-Based CD20xCD3 Bispecific Antibody (IGM-2323) for Enhanced T-Cell Dependent Killing with Minimal Cytokine Release

Ramesh Baliga, PhD, Keyu Li, PhD, Marigold Manlusoc, Paul Hinton, Dean Ng, PhD, Madeline Tran, Bing Shan, PhD, Hai Lu, Avneesh Saini, PhD, Sachi Rahman, Yuan Cao, PhD, Chitra Saraiya, Marvin Peterson, PhD, Steve Carroll, PhD, Daniel Chen, MD PhD, Bruce Keyt, PhD

Blood (2019) 134 (Supplement_1): 1574.

https://doi.org/10.1182/blood-2019-131650

Published: 2019

Journal Articles

Bifunctional PD-1 × αCD3 × αCD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia

Monika Herrmann, Christina Krupka, Katrin Deiser, Bettina Brauchle, Anetta Marcinek, Ana Ogrinc Wagner, Felicitas Rataj, Ralph Mocikat, Klaus H. Metzeler, Karsten Spiekermann, Sebastian Kobold, Nadja C. Fenn, Karl-Peter Hopfner, Marion Subklewe

Blood (2018) 132 (23): 2484–2494.

https://doi.org/10.1182/blood-2018-05-849802

Published: 2018

Includes: Supplemental data

Journal Articles

Development of a Bifunctional Checkpoint Inhibitory T Cell Engager (CiTE) to Reverse Adaptive Immune Escape in AML

Monika Herrmann, PhD, Christina Krupka, PhD, Katrin Deiser, PhD, Bettina Lindl, Ralph Mocikat, MD, Klaus H. Metzeler, MD, Karsten Spiekermann, MD, Sebastian Kobold, MD, Nadja Fenn, PhD, Karl-Peter Hopfner, PhD, Marion Subklewe, MD

Blood (2018) 132 (Supplement 1): 4069.

https://doi.org/10.1182/blood-2018-99-119624

Published: 2018

Journal Articles

Manufacture of Clinical-Grade Universal Antigen Presenting Cells (UAPC) for the Ex Vivo Expansion and Activation of Natural Killer (NK) Cells

Enli Liu, MD, Sonny Ang, PhD, Yijiu Tong, Li Li, MD, Rafet Basar, MD, Lucila Kerbauy, MD, May Daher, Pinaki P Banerjee, PhD, Francesca Lorraine Wei Inng Lim, MD, Indreshpal Kaur, PhD, Richard E Champlin, MD, Elizabeth J. Shpall, MD, Katy Rezvani, MD PhD

Blood (2018) 132 (Supplement 1): 2061.

https://doi.org/10.1182/blood-2018-99-118804

Published: 2018

Journal Articles

A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens

Blood (2018) 132 (18): 1911–1921.

https://doi.org/10.1182/blood-2018-04-843763

Published: 2018

Includes: Supplemental data

Journal Articles

TCR-Identical CD8+ T-Cells Can Have Distinct Killing Efficacy Determined By Events Beyond the T-Cell Receptor

Julie M Glanville, Anne-Marie Moody, Yanchun Peng, Stephan Taylor, Kristin Ladell, Geraldine Gillespie, Godelieve de Bree, Dilair Baban, Guillaume Stewart-Jones, Claire Cullen, Adam J Mead, MD PhD, Emmanuela Repapi, Sarah Rowland-Jones, Alison Simmons, David A Price, Tao Dong, Andrew McMichael

Blood (2017) 130 (Supplement 1): 692.

https://doi.org/10.1182/blood.V130.Suppl_1.692.692

Published: 2017

Journal Articles

TCR-Ligand Dissociation-Rate, a Reliable and Determining Parameter, Identifying Tumor-Reactive CD8 T Cells of High Avidity and Functional Potency

Nathalie Rufer, PhD MD, Mathilde Allard, PhD, Barbara Couturaud, Laura Carretero, PhD, Julien Schmidt, PhD, Minh Ngoc Duong, PhD, Petra Baumgaertner, PhD, Philippe Gannon, PhD, Daniel Speiser, MD, Michael Hebeisen, PhD

Blood (2016) 128 (22): 5894.

https://doi.org/10.1182/blood.V128.22.5894.5894

Published: 2016

Journal Articles

Development of Novel Non-Immunoglobulin Centyrin-Based Cars (CARTyrins) Targeting Human Bcma

Burton Earle Barnett, PhD, Xinxin Wang, PhD, David L. Hermanson, PhD, Yening Tan, B.S., Eric M. Osertag, MD PhD, Devon J. Shedlock, PhD

Blood (2016) 128 (22): 4557.

https://doi.org/10.1182/blood.V128.22.4557.4557

Published: 2016

Journal Articles

T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire

Ruth A. Ettinger, Pedro Paz, Eddie A. James, Devi Gunasekera, Fred Aswad, Arthur R. Thompson, Dana C. Matthews, Kathleen P. Pratt

Blood (2016) 128 (16): 2043–2054.

https://doi.org/10.1182/blood-2015-11-682468

Published: 2016

Includes: Supplemental data

Journal Articles

CD4 Treg and CD4 Tcon Utilize Distinct TCR Vbeta Repertoires in Response to Alloantigen

Anandharaman Veerapathran, PhD, Micheal Schell, PhD, Francisca Beato, B.S, TzuHua Juan, MPH, Sean Yoder, M.S, Brian C Betts, MD, Joseph A Pidala, MD, PhD, Claudio Anasetti, MD

Blood (2015) 126 (23): 4286.

https://doi.org/10.1182/blood.V126.23.4286.4286

Published: 2015

Journal Articles

Impact of Splenomegaly in the Presence of Negative PET FDG Avidity on Allogeneic Hematopoietic Cell Transplant Outcomes in Patients with Lymphoid Malignancies

Farhad Khimani, MD, Daniel K. Jeong, MD, Taiga Nishihori, MD, Ernesto Ayala, MD, Joseph A Pidala, MD, PhD, Frederick L. Locke, MD, Gage Kenneth, Julio C. Chavez, MD, Claudio Anasetti, MD, Mohamed A. Kharfan-Dabaja, MD

Blood (2015) 126 (23): 5524.

https://doi.org/10.1182/blood.V126.23.5524.5524

Published: 2015

Journal Articles

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

Cornelis A.M. van Bergen, Simone A.P. Van Luxemburg-Heijs, Matthijs Eefting, MD, Maria W. Honders, Inge Jedema, PhD, Constantijn J.M. Halkes, MD, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2013) 122 (21): 2014.

https://doi.org/10.1182/blood.V122.21.2014.2014

Published: 2013

Journal Articles

Prognostic Significance Of Positron Emission Tomography-Computed Tomography In Patients With Marginal Zone Lymphoma

Cheolwon Suh, Ji Hyun Park, Jr., MD, Dok Hyun Yoon, MD, Jooryung Huh, MD, Jin Sook Ryu, M.D Ph.D, Chan-Sik Park, MD

Blood (2013) 122 (21): 4324.

https://doi.org/10.1182/blood.V122.21.4324.4324

Published: 2013

Journal Articles

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

Nathalie Schmitt, Jacinta Bustamante, Laure Bourdery, Salah Eddine Bentebibel, Stephanie Boisson-Dupuis, Fran Hamlin, Mau V. Tran, Derek Blankenship, Virginia Pascual, Daniel A. Savino, Jacques Banchereau, Jean-Laurent Casanova, Hideki Ueno

Blood (2013) 121 (17): 3375–3385.

https://doi.org/10.1182/blood-2012-08-448902

Published: 2013

Includes: Supplemental data

Journal Articles

γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs

Cordula Gründer, Suzanne van Dorp, Samantha Hol, Esther Drent, Trudy Straetemans, Sabine Heijhuurs, Kirsten Scholten, Wouter Scheper, Zsolt Sebestyen, Anton Martens, Roland Strong, Jürgen Kuball

Blood (2012) 120 (26): 5153–5162.

https://doi.org/10.1182/blood-2012-05-432427

Published: 2012

Includes: Supplemental data

Journal Articles

Prevalence and Clinical Significance of Low Avidity HPA-1a Antibodies in Women Exposed to HPA-1a During Pregnancy

Julie A. Peterson, PhD, Adam Kanack, Dhirendra Nayak, Daniel W. Bougie, PhD, Janice McFarland, MD, Brian Curtis, PhD, Richard H. Aster, MD

Blood (2012) 120 (21): 266.

https://doi.org/10.1182/blood.V120.21.266.266

Published: 2012

NARROW

Antitumor immunity and T-cell avidity

A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity

Gastrointestinal (GI) Involvement with Non-Hodgkin's Lymphoma (NHL) Impacts Outcome; A Retrospective Single Tertiary Care Center Analysis of Clinico-Pathologic Characteristics Provides an Alternate Insight to Presentation and Outcome

Elispots and Ex Vivo Expansion of FVIII-Specific T-Cell Clones Confirm Specificity of CD4 + T-Cell Responses to Self-FVIII in Healthy Non-Hemophilic Blood Donors

High Avidity IgM-Based CD20xCD3 Bispecific Antibody (IGM-2323) for Enhanced T-Cell Dependent Killing with Minimal Cytokine Release

Bifunctional PD-1 × αCD3 × αCD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia

Development of a Bifunctional Checkpoint Inhibitory T Cell Engager (CiTE) to Reverse Adaptive Immune Escape in AML

Manufacture of Clinical-Grade Universal Antigen Presenting Cells (UAPC) for the Ex Vivo Expansion and Activation of Natural Killer (NK) Cells

A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens

TCR-Identical CD8+ T-Cells Can Have Distinct Killing Efficacy Determined By Events Beyond the T-Cell Receptor

TCR-Ligand Dissociation-Rate, a Reliable and Determining Parameter, Identifying Tumor-Reactive CD8 T Cells of High Avidity and Functional Potency

Development of Novel Non-Immunoglobulin Centyrin-Based Cars (CARTyrins) Targeting Human Bcma

T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire

CD4 Treg and CD4 Tcon Utilize Distinct TCR Vbeta Repertoires in Response to Alloantigen

Impact of Splenomegaly in the Presence of Negative PET FDG Avidity on Allogeneic Hematopoietic Cell Transplant Outcomes in Patients with Lymphoid Malignancies

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

Prognostic Significance Of Positron Emission Tomography-Computed Tomography In Patients With Marginal Zone Lymphoma

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs

Prevalence and Clinical Significance of Low Avidity HPA-1a Antibodies in Women Exposed to HPA-1a During Pregnancy

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American Society of Hematology

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