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Journal Articles

Topoisomerase I-DNA Covalent Complexes in Myeloid Malignancies: A Potential Biomarker for Topoisomerase I Inhibitor Sensitivity

Mira A. Kohorst, MD, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Cristina Correia, Keith W. Pratz, MD, B. Douglas Smith, MD, Scott H. Kaufmann, MD PhD

Blood (2018) 132 (Supplement 1): 5146.

https://doi.org/10.1182/blood-2018-99-115667

Published: 2018

Journal Articles

New Bone Marrow Failure Genes: DNAJC21 and ERCC6L2

Inderjeet Dokal, MD

Blood (2017) 130 (Supplement 1): SCI-22.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-22.SCI-22

Published: 2017

Journal Articles

Irinotecan Induces Complete Remission in MLL -Rearranged Acute Lymphoblastic Leukemia Xenografts

Patricia Garrido Castro, PhD, Mark Kerstjens, MSc, Sandra S Pinhanços, MSc, Pauline Schneider, BSc, Priscilla Wander, MSc, Rob Pieters, MD PhD, Ronald Stam, PhD

Blood (2017) 130 (Supplement 1): 3877.

https://doi.org/10.1182/blood.V130.Suppl_1.3877.3877

Published: 2017

Journal Articles

Molecular and Pharmacological Inhibition of ATP Binding Cassette Transporter ABCB6 Decreases Chemoresistance in Acute Myeloid Leukemia

Sreeja Karathedath, PhD, Raveen Stephen Stallon Illangeswaran, M.Sc.,, Saswati Das, MSc., Bharathi M Rajamani, Srujan Kumar Marepally, M.Sc., PhD, Partha Kasturi, PhD, Vikram Mathews, MD DM, Shaji Ramachandran Velayudhan, M.Sc., PhD, Poonkuzhali Balasubramanian, MSc, PhD

Blood (2017) 130 (Supplement 1): 1254.

https://doi.org/10.1182/blood.V130.Suppl_1.1254.1254

Published: 2017

Journal Articles

Impact and Function of Somatic PHF6 Mutations in Myeloid Neoplasms

Brittney Dienes, Bartlomiej P Przychodzen, Michael Clemente, MS, Wenyi Shen, MD, Chantana Polprasert, MD, Naoko Hosono, MDPhD, Satoru Miyano, PhD, Yuichi Shiraishi, PhD, Kenichi Yoshida, MD, Seishi Ogawa, MD PhD, Mikkael A. Sekeres, MD MS, Yogen Saunthararajah, MD, Jaroslaw P. Maciejewski, MD PhD, Hideki Makishima, MD PhD

Blood (2014) 124 (21): 3581.

https://doi.org/10.1182/blood.V124.21.3581.3581

Published: 2014

Journal Articles

AML Specific Targeted Drugs Identified By Drug Sensitivity and Resistance Testing: Comparison of Ex Vivo Patient Cells with in Vitro Cell Lines

Disha Malani, MSc, Astrid Murumägi, PhD, Bhagwan Yadav, MSc, Tea Pemovska, MSc, John Patrick Mpindi, MSc, Mika Kontro, MD, Tero Aittokallio, PhD, Caroline A Heckman, PhD, Kimmo Porkka, MD PhD, Krister Wennerberg, PhD, Maija Wolf, PhD, Olli Kallioniemi, MD PhD

Blood (2014) 124 (21): 2163.

https://doi.org/10.1182/blood.V124.21.2163.2163

Published: 2014

Journal Articles

Cotylenin Α, a Fusicoccane Diterpene Glycoside with a Complex Sugar Moiety, and Vincristine Synergistically Inhibit the Growth of Myeloma Cell in Vitro and in Vivo

Tsutomu Takahashi, MD PhD, Yoshio Honma, PhD, Koshi Kawakami, MDPhD, Junji Suzumiya

Blood (2014) 124 (21): 5721.

https://doi.org/10.1182/blood.V124.21.5721.5721

Published: 2014

Journal Articles

Impact Of Rad50 On Telomere Recombination Mechanisms In Primary Bone Marrow and B-Cell Lymphomas Lacking Telomerase

Tammy Morrish, Vivek Behera, Joshua Budman, Stephen Dria, Michelle Morgan, David Velliquette, Dulat Bekbolysnov, Alyza Skaist, Sarah Wheelan

Blood (2013) 122 (21): 3807.

https://doi.org/10.1182/blood.V122.21.3807.3807

Published: 2013

Journal Articles

Flow Cytometric Quantification of All Cell Cycle Phases and Apoptosis in a Two-Color Fluorescence Plot

Olivier Herault, MD, PhD, Christine Vignon, PhD

Blood (2012) 120 (21): 4720.

https://doi.org/10.1182/blood.V120.21.4720.4720

Published: 2012

Journal Articles

AR-67, a DNA Topo-Isomerase I Inhibitor, Demonstrates Acceptable Tolerability and Preliminary Activity in a Phase II Trial of Patients with Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML),

Naval Daver, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, Gautam Borthakur, Farhad Ravandi, MD, Tapan Kadia, Zeev Estrov, Marina Konopleva, M.D., Ph.D., Stefan Faderl, MD, Jorge E. Cortes

Blood (2011) 118 (21): 3820.

https://doi.org/10.1182/blood.V118.21.3820.3820

Published: 2011

Journal Articles

A Role for Splicing Factors and R-Loop Formation in the Pathophysiology of Fanconi Anemia.

Allison M Green, M.Phil., Natalie Collins, M.D., PhD, Simonne Longerich, PhD, Patrick Sung, PhD, Gary M Kupfer, M.D.

Blood (2010) 116 (21): 3371.

https://doi.org/10.1182/blood.V116.21.3371.3371

Published: 2010

Journal Articles

Some CLL Cells Bind Myosin-Exposed Apoptotic Cells. Exposure of Cytoplasmic Myosin Results From Transfer of Caspase-3 Dependent Cleavage Products to the Outer Cell Membrane

Xiaoxuan Cui, MD, PhD, Lu Zhang, MS, Amanda R Magli, BSE, Rosa Catera, PhD, Jonathan E Kolitz, MD, Steven L. Allen, MD, Kanti R Rai, MD, Nicholas Chiorazzi, MD, Charles C Chu, PhD

Blood (2010) 116 (21): 3900.

https://doi.org/10.1182/blood.V116.21.3900.3900

Published: 2010

Journal Articles

Multi-Dimensional Resistance Phenotype Allows Subpopulation of Quiescent Chronic Myeloid Leukemia Stem Cells to Universally Escape From Therapeutic Attack

Inge Jedema, PhD, Linda van Dreunen, Renate S. Hagedoorn, J.H. Frederik Falkenburg, MD, PhD

Blood (2010) 116 (21): 203.

https://doi.org/10.1182/blood.V116.21.203.203

Published: 2010

Journal Articles

Biological and Molecular Characterization by Integrative Genomics Approach of CMA-03/06, a Newly Established Interleukin-6 Independent Variant of the CMA-03 Human Myeloma Cell Line.

Donata Verdelli, PhD, Lucia Nobili, PhD, Katia Todoerti, PhD, Laura Mosca, PhD, Sonia Fabris, PhD, Giorgio Lambertenghi Deliliers, MD, Antonino Neri, MD

Blood (2009) 114 (22): 1814.

https://doi.org/10.1182/blood.V114.22.1814.1814

Published: 2009

Journal Articles

Tanespimycin Reverses Bortezomib-Induced Inhibition of Granulopoiesis.

Bruce D. Car, BVSc, PhD, DACVP, DABT, Oliver P. Flint, PhD, Jan Oberdoerster, PhD, DABT, Jennifer Price, William R. Foster, Brian Gemzik, PhD, David Berman, MD, PhD

Blood (2009) 114 (22): 3846.

https://doi.org/10.1182/blood.V114.22.3846.3846

Published: 2009

Journal Articles

Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M

Thiyam Ramsing Singh, Sietske T. Bakker, Sheba Agarwal, Michael Jansen, Elke Grassman, Barbara C. Godthelp, Abdullah Mahmood Ali, Chang-hu Du, Martin A. Rooimans, Qiang Fan, Kebola Wahengbam, Jurgen Steltenpool, Paul R. Andreassen, David A. Williams, Hans Joenje, Johan P. de Winter, Amom Ruhikanta Meetei

Blood (2009) 114 (1): 174–180.

https://doi.org/10.1182/blood-2009-02-207811

Published: 2009

Includes: Supplemental data

Journal Articles

Frequently Occurring B-CLL Antibodies Recognize Apoptotic Cells That Expose Non-Muscle Myosin Heavy Chain IIA

Charles C Chu, PhD, Rosa Catera, PhD, Sebastien Didier, MS, Lu Zhang, MA, Briana Agagnina, Steven L Allen, MD, Kanti R Rai, MD, Nicholas Chiorazzi, MD

Blood (2008) 112 (11): 3123.

https://doi.org/10.1182/blood.V112.11.3123.3123

Published: 2008

Journal Articles

Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member B (ANP32B), a Novel Caspase-3 Substrate, Exerts Anti-Apoptotic Effects on Acute Myeloid Leukemic Cells.

Yun Yu, Shao-Ming Shen, Li-Shun Wang, Qian Zhao, Guo-Qiang Chen

Blood (2008) 112 (11): 1337.

https://doi.org/10.1182/blood.V112.11.1337.1337

Published: 2008

Journal Articles

Horizontal Gene Transfer through Apoptotic Bodies Confers a Possible Mechanism of Epithelial Chimerism after Allogeneic Hematopoietic Cell Transplantation.

Miguel Waterhouse, Maria Themeli, Jurgen Finke, Alexandros Spyridonidis

Blood (2008) 112 (11): 2320.

https://doi.org/10.1182/blood.V112.11.2320.2320

Published: 2008

Journal Articles

Early Apoptotic Cells Detected by 7-Aminoactinomycin and Annexin V Are Positive for Fluorescence Tagged Activated Caspase-9 Inhibitor (Red-LEHD-FMK)

Kar Lai Lee, Frances M Gibson

Blood (2008) 112 (11): 4728.

https://doi.org/10.1182/blood.V112.11.4728.4728

Published: 2008

NARROW

Topoisomerase I-DNA Covalent Complexes in Myeloid Malignancies: A Potential Biomarker for Topoisomerase I Inhibitor Sensitivity

New Bone Marrow Failure Genes: DNAJC21 and ERCC6L2

Irinotecan Induces Complete Remission in MLL -Rearranged Acute Lymphoblastic Leukemia Xenografts

Molecular and Pharmacological Inhibition of ATP Binding Cassette Transporter ABCB6 Decreases Chemoresistance in Acute Myeloid Leukemia

Impact and Function of Somatic PHF6 Mutations in Myeloid Neoplasms

AML Specific Targeted Drugs Identified By Drug Sensitivity and Resistance Testing: Comparison of Ex Vivo Patient Cells with in Vitro Cell Lines

Cotylenin Α, a Fusicoccane Diterpene Glycoside with a Complex Sugar Moiety, and Vincristine Synergistically Inhibit the Growth of Myeloma Cell in Vitro and in Vivo

Impact Of Rad50 On Telomere Recombination Mechanisms In Primary Bone Marrow and B-Cell Lymphomas Lacking Telomerase

Flow Cytometric Quantification of All Cell Cycle Phases and Apoptosis in a Two-Color Fluorescence Plot

AR-67, a DNA Topo-Isomerase I Inhibitor, Demonstrates Acceptable Tolerability and Preliminary Activity in a Phase II Trial of Patients with Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML),

A Role for Splicing Factors and R-Loop Formation in the Pathophysiology of Fanconi Anemia.

Some CLL Cells Bind Myosin-Exposed Apoptotic Cells. Exposure of Cytoplasmic Myosin Results From Transfer of Caspase-3 Dependent Cleavage Products to the Outer Cell Membrane

Multi-Dimensional Resistance Phenotype Allows Subpopulation of Quiescent Chronic Myeloid Leukemia Stem Cells to Universally Escape From Therapeutic Attack

Biological and Molecular Characterization by Integrative Genomics Approach of CMA-03/06, a Newly Established Interleukin-6 Independent Variant of the CMA-03 Human Myeloma Cell Line.

Tanespimycin Reverses Bortezomib-Induced Inhibition of Granulopoiesis.

Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M

Frequently Occurring B-CLL Antibodies Recognize Apoptotic Cells That Expose Non-Muscle Myosin Heavy Chain IIA

Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member B (ANP32B), a Novel Caspase-3 Substrate, Exerts Anti-Apoptotic Effects on Acute Myeloid Leukemic Cells.

Horizontal Gene Transfer through Apoptotic Bodies Confers a Possible Mechanism of Epithelial Chimerism after Allogeneic Hematopoietic Cell Transplantation.

Early Apoptotic Cells Detected by 7-Aminoactinomycin and Annexin V Are Positive for Fluorescence Tagged Activated Caspase-9 Inhibitor (Red-LEHD-FMK)

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American Society of Hematology

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American Society of Hematology

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