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Journal Articles

Administration of Andexanet Alfa for Direct Factor Xa Inhibitor Reversal Precludes Therapeutic Heparinization for Cardiopulmonary Bypass

Nabil K. Thalji, MD PhD, Prakash A Patel, MD, Rodney M. Camire, PhD

Blood (2019) 134 (Supplement_1): 3640.

https://doi.org/10.1182/blood-2019-125955

Published: 2019

Journal Articles

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Ahmed Kouta, Walter Jeske, PhD, Rick Duff, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 165.

https://doi.org/10.1182/blood-2019-131943

Published: 2019

Journal Articles

Aptamers as Rapid Onset and Rapidly Reversible Antithrombotic Agents

Bruce A. Sullenger, PhD

Blood (2019) 134 (Supplement_1): SCI-16.

https://doi.org/10.1182/blood-2019-121056

Published: 2019

Journal Articles

Signaling mechanisms inducing hyporesponsiveness of phagocytes during systemic inflammation

Nicole Freise, Alina Burghard, Theresa Ortkras, Niklas Daber, Achmet Imam Chasan, Saskia-L. Jauch, Olesja Fehler, Julia Hillebrand, Mosab Schakaki, Jessica Rojas, Bodo Grimbacher, Thomas Vogl, Andreas Hoffmeier, Sven Martens, Johannes Roth, Judith Austermann

Blood (2019) 134 (2): 134–146.

https://doi.org/10.1182/blood.2019000320

Published: 2019

Includes: Supplemental data

Journal Articles

Cleavage of Anti-PF4/H IgG Antibodies By Ides, and Potential Benefit in the Treatment of Heparin-Induced Thrombocytopenia

Claire Kizlik-Masson, Quentin Deveuve, Yuhang Zhou, MD PhD, Caroline Vayne, PharmD, Gilles Thibault, PharmD, PhD, Steven Edward McKenzie, MD PhD, Claire Pouplard, PharmD, PhD, Stéphane Loyau, Jérôme Rollin, PhD, Yves Gruel, MD PhD

Blood (2018) 132 (Supplement 1): 518.

https://doi.org/10.1182/blood-2018-99-114450

Published: 2018

Journal Articles

Heparin Vs Direct Thrombin Inhibitors in Patients with Previous HIT Undergoing Cardiothoracic Surgery: The Cleveland Clinic Experience

Daniel S Carlson, DO, Keith R. McCrae, MD, Shruti Chaturvedi, MBBS,MS

Blood (2018) 132 (Supplement 1): 425.

https://doi.org/10.1182/blood-2018-99-115375

Published: 2018

Journal Articles

Anti-PF4/Heparin Antibody Levels in Bacteremia, Fungemia and Sepsis

Satish Maharaj, MBBS, Simone Chang, MBBS, Karan Seegobin, MBBS, Fauzia Rana, MD, Marwan Shaikh, MD

Blood (2018) 132 (Supplement 1): 3752.

https://doi.org/10.1182/blood-2018-99-117917

Published: 2018

Journal Articles

Platelet Trends Are Not Predictive of Heparin Induced Thrombocytopenia in Patients on Extra Corporeal Membrane Oxygenation

Daniel Stapor, Anil Rengan, MD, Mark Weiner, MD, Huaqing Zhao, MS, PhD, Nadia Ali, MD

Blood (2018) 132 (Supplement 1): 3767.

https://doi.org/10.1182/blood-2018-99-115396

Published: 2018

Journal Articles

Fibrinogen Concentrate Vs. Cryoprecipitate for Acquired Hypofibrinogenemia in Cardiac Surgery — the FIBRES Study

Jo Carroll, Keyvan Karkouti

Blood (2018) 132 (Supplement 1): 5080.

https://doi.org/10.1182/blood-2018-99-118078

Published: 2018

Journal Articles

Incidence of Thrombocytopenia and Heparin Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO) Compared to Cardiopulmonary Bypass and the Limited Sensitivity of Pre-Test Probability Score

Deepa Jayakody Arachchillage, MD MRCP, FRCPath, Sanjay Khanna, Christophe Vandenbriele, Jonthan Dutton, Alex Rosenberg, MRCP, FCICM, FFICM, TC Aw, FRCA, Winston Banya, Maurizio Passariello, EDIC, Michael Laffan, DM, FRCP, FRCPath, Stephane Ledot, EDIC, MD, Brijesh Patel, MRCP, FRCA, FFICM , PhD

Blood (2018) 132 (Supplement 1): 2451.

https://doi.org/10.1182/blood-2018-99-119143

Published: 2018

Journal Articles

Frequency of Anti-PF4/Heparin Antibodies in Patients Treated with Extra-Corporeal Membrane Oxygenation and Detection By Sensitized Serotonin Release Assay of Pathogenic Heparin-Induced Thrombocytopenia Antibodies

Caroline Vayne, PharmD, Marc-Antoine May, MD, Thierry Bourguignon, MD PhD, Eric Lemoine, MD, Eve-Anne Guéry, PharmD, Jérôme Rollin, PhD, Yves Gruel, MD PhD, Claire Pouplard, PharmD, PhD

Blood (2018) 132 (Supplement 1): 1143.

https://doi.org/10.1182/blood-2018-99-114571

Published: 2018

Journal Articles

Laboratory Assays to Address the Problem of Heparin-Protamine Balance Following Neonatal Open Heart Surgery

Julie A. Peterson, PhD, Susan A. Maroney, DVM, PhD, Wes Zwifelhofer, BS, Jeremy P. Wood, PhD, Rachel Bercovitz, MD MS, Ronald K. Woods, MD PhD, Alan E. Mast, MDPhD

Blood (2017) 130 (Supplement 1): 1111.

https://doi.org/10.1182/blood.V130.Suppl_1.1111.1111

Published: 2017

Journal Articles

Plasma Proteolytic Cascade Activation and Control during Neonatal Cardiopulmonary Bypass Surgery

Susan A. Maroney, DVM, PhD, Julie A. Peterson, PhD, Wes Zwifelhofer, BS, Rachel Bercovitz, MD MS, Ronald K. Woods, MD PhD, Alan E. Mast, MDPhD

Blood (2017) 130 (Supplement 1): 2356.

https://doi.org/10.1182/blood.V130.Suppl_1.2356.2356

Published: 2017

Journal Articles

Three Factor Prothrombin Complex Concentrates in Cardiac Surgery: A Novel Algorithmic Approach to Perioperative Bleeding

Nazish Khalid Hashmi, MD, Kamrouz Ghadimi, Jacob Schroder, Jerrold Levy, MD, Ian J Welsby, MD

Blood (2016) 128 (22): 5035.

https://doi.org/10.1182/blood.V128.22.5035.5035

Published: 2016

Journal Articles

Efficacy and Safety of Prothrombin Complex Concentrate in Patients Undergoing Major Cardiac Surgery

Deepa Jayakody Arachchillage, Simona Deplano, Eleanor Dunnett, Steve Owen, Louise Tillyer, Michael Laffan

Blood (2016) 128 (22): 3852.

https://doi.org/10.1182/blood.V128.22.3852.3852

Published: 2016

Journal Articles

RNA Aptamer Against FXa Synergizes with FXa Catalytic Site Inhibitors to Effectively and Reversibly Anticoagulate Blood in an Ex Vivo Oxygenator Circuit

Ruwan Gunaratne, MA, James Frederiksen, MD, Nabil K. Thalji, BS, Michelle D Ho, Gowthami M Arepally, MD, Rodney M. Camire, PhD, Bruce A. Sullenger, PhD

Blood (2016) 128 (22): 3823.

https://doi.org/10.1182/blood.V128.22.3823.3823

Published: 2016

Journal Articles

High Resolution Igh Repertoire Analysis Reveals the Human Fetal Liver As the Origin of Life-Long, Innate B Lymphopoiesis

Anindita Roy, MDPhD, Vojtech Bystry, Georg Bohn, Katerina Goudevenou, Tomas Reigl, Maria Papaioannou, Adam Krejci, Sorcha O'Byrne, Aristeidis Chaidos, Andrea Grioni, Nikos Darzentas, Irene Roberts, Anastasios Karadimitris

Blood (2016) 128 (22): 127.

https://doi.org/10.1182/blood.V128.22.127.127

Published: 2016

Journal Articles

Characterization of Human and Murine Anti-Protamine/Heparin Antibodies

Grace M. Lee, MD, Manali Joglekar, MS, Sanjay Khandelwal, Rui Qi, BS, Lubica Rauova, MD PhD, Gowthami M Arepally, MD

Blood (2015) 126 (23): 3461.

https://doi.org/10.1182/blood.V126.23.3461.3461

Published: 2015

Journal Articles

Impact of Four-Factor Prothrombin Complex Concentrate on Urgent Warfarin-Reversal in Patients with Ventricular Assist Devices Going for Heart Transplants

Ding Wen Wu, MD PhD, Uehlinger Joan, MD, Szymanski James, MD, Mohandas Kala, MD, Ronald Walsh, MD, Sadiqa Karim, MD, Evan Himchak, MD, Ritu Gupta, MD, Daniel Goldstein, MD

Blood (2015) 126 (23): 3568.

https://doi.org/10.1182/blood.V126.23.3568.3568

Published: 2015

Journal Articles

Lung Damage and Thrombocytopenia

Mo Yang, PhD, En Yu Liang, Li Xia Zhou, Beng H Chong, PhD, Chunfu Li, MD

Blood (2015) 126 (23): 4638.

https://doi.org/10.1182/blood.V126.23.4638.4638

Published: 2015

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Administration of Andexanet Alfa for Direct Factor Xa Inhibitor Reversal Precludes Therapeutic Heparinization for Cardiopulmonary Bypass

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Aptamers as Rapid Onset and Rapidly Reversible Antithrombotic Agents

Signaling mechanisms inducing hyporesponsiveness of phagocytes during systemic inflammation

Cleavage of Anti-PF4/H IgG Antibodies By Ides, and Potential Benefit in the Treatment of Heparin-Induced Thrombocytopenia

Heparin Vs Direct Thrombin Inhibitors in Patients with Previous HIT Undergoing Cardiothoracic Surgery: The Cleveland Clinic Experience

Anti-PF4/Heparin Antibody Levels in Bacteremia, Fungemia and Sepsis

Platelet Trends Are Not Predictive of Heparin Induced Thrombocytopenia in Patients on Extra Corporeal Membrane Oxygenation

Fibrinogen Concentrate Vs. Cryoprecipitate for Acquired Hypofibrinogenemia in Cardiac Surgery — the FIBRES Study

Incidence of Thrombocytopenia and Heparin Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO) Compared to Cardiopulmonary Bypass and the Limited Sensitivity of Pre-Test Probability Score

Frequency of Anti-PF4/Heparin Antibodies in Patients Treated with Extra-Corporeal Membrane Oxygenation and Detection By Sensitized Serotonin Release Assay of Pathogenic Heparin-Induced Thrombocytopenia Antibodies

Laboratory Assays to Address the Problem of Heparin-Protamine Balance Following Neonatal Open Heart Surgery

Plasma Proteolytic Cascade Activation and Control during Neonatal Cardiopulmonary Bypass Surgery

Three Factor Prothrombin Complex Concentrates in Cardiac Surgery: A Novel Algorithmic Approach to Perioperative Bleeding

Efficacy and Safety of Prothrombin Complex Concentrate in Patients Undergoing Major Cardiac Surgery

RNA Aptamer Against FXa Synergizes with FXa Catalytic Site Inhibitors to Effectively and Reversibly Anticoagulate Blood in an Ex Vivo Oxygenator Circuit

High Resolution Igh Repertoire Analysis Reveals the Human Fetal Liver As the Origin of Life-Long, Innate B Lymphopoiesis

Characterization of Human and Murine Anti-Protamine/Heparin Antibodies

Impact of Four-Factor Prothrombin Complex Concentrate on Urgent Warfarin-Reversal in Patients with Ventricular Assist Devices Going for Heart Transplants

Lung Damage and Thrombocytopenia

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